A Unique Trinucleotide-Bloc Mutation-Based Two SARS-CoV-2 Genotypes with Potential Pathogenic Impacts by Mustak Ibn Ayub

“…Although some mutations provide benefits to the virus against human immune response, others may result in their reduced pathogenicity and virulence. By analyzing more than 3000 high-coverage, complete sequences deposited in the GISAID database up to April 2020, here I report the uniqueness of the 28881–28883: GGG > AAC trinucleotide-bloc mutation in the SARS-CoV-2 genome that results in two substrains, described here as SARS-CoV-2g (28881–28883: GGG genotype) and SARS-CoV-2a (28881–28883: AAC genotype). …”
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The dynamics of a delay model of hepatitis B virus infection with logistic hepatocyte growth by Steffen Eikenberry, Sarah Hews, John D. Nagy, Yang Kuang

“…We show that when thebasic reproductive number is greater than 1 there exists a biologically meaningfulchronic steady state, and the stability of this steady state is dependent upon boththe rate of hepatocyte regeneration and the virulence of the disease. When thechronic steady state is unstable, simulations show the existence of an attractingperiodic orbit. …”
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Mechanism of Action of Lacticaseibacillus paracasei HNU502 and Fecal Microbiota Transplantation in Alleviating Antibiotic Side Effects by CHEN Lin, LI Ao, LI Jiahe, ZHANG Zeng, ZHANG Jiachao

“…Moreover, the two approaches ameliorated the metabolic disorders of short-chain fatty acids, inhibited the secretion of pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α as well as blood urea nitrogen (BUN), and effectively reduced virulence factor enrichment. This study contributes to a better understanding of the link between human health and gut microbiota, and provides new therapeutic options for mitigating antibiotic side effects, which is of great significance for improving patients’ health status and quality of life.…”
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Cryptosporidiosis in a Zoonotic Gastrointestinal Disorder Perspective by Thivya Balendran, Devika Iddawela, Sajanee Lenadora

“…We analyzed reports on Cryptosporidium in immunocompromised patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), cancer, primary immunodeficiency, and organ transplant recipients. 134 Articles describing epidemiology, related risk factors, clinical presentation, diagnosis, and possible treatments in the light of pathogenesis, pathophysiology, and virulence factors of Cryptosporidium and immunology of the host are summarized in this study. …”
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A comparative study of replicative properties of antitumor recombinant vaccinia viruses on human glioblastoma cell culture U87 and monkey kidney cell culture CV-1 by R. A. Maksyutov, I. V. Kolosova, T. V. Tregubchak, I. A. Razumov, S. N. Shchelkunov

“…Furthermore, the virus with five virulence genes deleted (genes encoding hemagglutinin, γ-interferonbinding protein, thymidine kinase, complementbinding protein and Bcl2-like inhibitor of apoptosis), which has significantly lower reactogenicity and neurovirulence compared to the original strain LIVP of VACV, was studied. …”
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Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese by Fengju Zhang, Tingzhun Zhu, Zhongjun Zhou, Yudong Wu, Yang Li

“…Further studies are needed to confirm finally whether the two genes are the virulence genes of PM.…”
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Aspergillus fumigatus ctf1–a novel zinc finger transcription factor involved in azole resistance by Xiao Gong, Heng Zhang, Wenxu Cheng, Zhangxuan He, Tianyan Ma, Tian Chen, Yi Sun

“…Thus, our results on the function of ctf1 contribute to the elucidation of the mechanisms underlying A. fumigatus resistance and the factors associated with A. fumigatus virulence.…”
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Effect of innate and induced immunity on infectious bursal disease pathogenesis by A. N. Semina

“…Infection with highly virulent virus strain or chicks’ infection at early age after recovery or subclinical infection results in immunosuppression with more severe consequences. …”
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<i>Trachemys scripta</i> Eggs as Part of a Potential In Vivo Model for Studying Sea Turtle Egg Fusariosis by María Martínez-Ríos, Laura Martín-Torrijos, Javier Diéguez-Uribeondo

“…The pathogen showed high virulence properties (e.g., high disease incidence, severity, and low hatching success) and its ability to modify the pH in both the egg surface and culture media, confirming previously described fungal pathogen models. …”
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A comprehensive review of mycoviruses infecting the plant pathogenic fungus Rosellinia necatrix by Sidra Hassan, Robert H. A. Coutts, Atif Jamal, Ioly Kotta-Loizou, Ioly Kotta-Loizou

“…This article provides a comprehensive overview of mycoviruses infecting plant pathogenic fungus Rosellinia necatrix causing white root rot, including the prevalence of their occurrence, their taxonomic classification, their genomic organization and structure, impacts on their fungal host in terms of phenotype in general and virulence in particular, and their ecological interactions including transmission. …”
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Microbiota Associated with Infections of the Jaws by Elerson Gaetti-Jardim, Luis Fernando Landucci, Kathlenn Liezbeth de Oliveira, Iracy Costa, Robson Varlei Ranieri, Ana Cláudia Okamoto, Christiane Marie Schweitzer

“…This paper discuss the possibility of spread of these infections and their clinical implications for dentistry, as well as their etiology and aspects related to microbial virulence and pathogenesis.…”
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Elucidation of peptide screen for targeted identification of Yersinia pestis by nano-liquid chromatography tandem mass spectrometry by Priya Rani, Syed Imteyaz Alam, Sandeep Singh, Subodh Kumar

“…Additionally, 148 peptides were discovered from proteins of Y. pestis-specific plasmids and chromosomal-associated virulence markers. To validate this screen of 209 peptides, various concentrations of Y. pestis (ranging from 1.3 × 108 to 1.3 × 105 cfu) were spiked into garden soil. …”
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Fertility, gestation outcome and parasite congenital transmissibility in mice infected with TcI, TcII and TcVI genotypes of Trypanosoma cruzi. by Sabrina Cencig, Nicolas Coltel, Carine Truyens, Yves Carlier

“…This study should encourage further investigations using other parasite strains and genotypes to explore the role of virulence and other factors, as well as the mechanisms of such effects on gestation and on the establishment of congenital infection.…”
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Aggressive Infection by K1/ST1265 Klebsiella pneumoniae Leading to Multiple Abscesses: Case Report and Literature Review by Chen L, Qiu C, Lu Y, Lin J, Xu L

“…K1/ST1265 hvKp exhibits exceptionally high virulence and invasiveness, necessitating broad awareness and vigilant monitoring.Keywords: Klebsiella pneumoniae, liver abscess, prostate abscess, brain abscess, serotype K1, sequence type 1265…”
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In vitro photodynamic therapy of Candida albicans, the cause of vulvovaginal candidiasis, is enhanced by Bacillus and Enterococcus probiotics by Zeinab Ghanbari, Ali Makhdoumi

“…Methods: This study examines the combined effects of probiotics (Bacillus and Enterococcus isolated from the fermented pickles) and PDT (using red laser (655 nm, 18 J/cm2) as a light source and methylene blue dye (30 mg/mL) as a photosensitizer) on the in vitro virulence activity of C. albicans including growth, biofilm formation, antifungal resistance, biofilm elimination, and biofilm dispersion. …”
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Molecular Detection of Candida tropicalis Isolated from Immunocompromised Patients with Otitis Media by Aymen Nazar Khalil, Abbas M. Ammari

“…Als2 gene may be play an important role in the virulence of C. tropicalis among immunocompromised patients with otitis media. …”
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Resistance of modern spring barley cultivars to harmful organisms by A. G. Semenova, A. V. Anisimova, O. N. Kovaleva

“…In 2019 and 2020, the incidence of brown rust and powdery mildew was significant, and the virulence of fritfly increased greatly in the same years. …”
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Mercury Intrusion Effects Modelled in Pores with Axial Symmetry and Attenuated Cross Section by Isaac Kornhauser, Carlos Felipe, Juan Marcos Esparza, Armando Domínguez, Fernando Rojas

“…Virtual penetration curves indicate Laplace stable or unstable states as well as the virulence of the irreversible penetration of pores with a varying cross section. …”
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COVID-19 and Decision-Making for Pregnant Women: Taking or Relinquishing Control in Response to a Pandemic by Elizabeth Kaselitz, Chelsea Finkbeiner, Sarah Javaid, Sarah Barringer, Sarah D. Compton, Maria Muzik, Cheryl A. Moyer

“…From the initial unknowns about its virulence during pregnancy, to frequent and rapidly changing hospital guidelines for prenatal care and delivery, pregnant women have felt intense uncertainty and, based on recent research, increased anxiety. …”
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Isolation and Characterization of Gram-Negative Bacterial Species from Pasteurized Dairy Products: Potential Risk to Consumer Health by Solomon H. Mariam

“…Here, samples of pasteurized dairy products were subjected to enrichment/selective cultures to test for possible Salmonella contamination, followed by growth on/in various media to test for phenotypic properties and some virulence characteristics of isolates (catalase, urease, oxidase, gelatinase, etc.). …”
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