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521
The History of Methicillin-Resistant Staphylococcus aureus in Brazil
Published 2020-01-01“…Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance. The high adaptability and pathogenic profile of MRSA clones contributed to its spread in hospital and community settings. …”
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522
Water pollution, cholera, and the role of probiotics: a comprehensive review in relation to public health in Bangladesh
Published 2025-01-01“…Recent probiotic advancements include engineering strains that disrupt V. cholerae biofilms and inhibit their virulence. Integrating probiotics with traditional cholera control measures could significantly enhance their effectiveness and provide a multifaceted approach to combating this persistent disease. …”
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523
Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae.
Published 2025-01-01“…Klebsiella pneumoniae is a typical opportunistic pathogen that exhibits multiple virulence factors and antibiotic resistance conditioning mechanisms. …”
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524
Potency of the Consortium of Pseudomonad fluorescent pf-142 and Bacillus mycoides Isolates Against Bacterial Wilt Disease In-Vitro
Published 2024-12-01“…Based on the study, it was known that R. solanacearum caused wilting in chili pepper plants with high virulence. Pseudomonad fluorescent pf-142 and B. mycoides did not produce an inhibition zone, indicating that both were compatible. …”
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525
A CRISPR-Cas9 system protecting E. coli against acquisition of antibiotic resistance genes
Published 2025-01-01“…However, one concern with the use of live bacteria is the risk of the bacteria acquiring genes encoding for AMR or virulence factors through horizontal gene transfer (HGT), and the transformation of the probiotic into a superbug. …”
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526
Convergent evolution of oxidized sugar metabolism in commensal and pathogenic microbes in the inflamed gut
Published 2025-01-01“…Previously considered a pathogen virulence factor, oxidized sugar metabolism is also present in specific commensals and may contribute to their increased relative abundance in gastrointestinal inflammation.…”
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527
Evolution of parasite transmission dispersion
Published 2025-01-01“…Furthermore, parasite adaptation can maintain increased transmission dispersion at endemic equilibria if virulence differs between hosts in a heterogeneous population. …”
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528
Helicobacter pylori Infection in Gastroesophageal Reflux Disease in the Asian Countries
Published 2015-01-01“…The interactions between genetic factors and the virulence of H. pylori infection may be the reason for the low prevalence of GERD in Asian countries. …”
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529
Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
Published 2025-01-01“…Capsule, an essential virulence determinant, is a major cause of the enhanced pathogenicity of hvKP and thus represents an attractive drug target to prevent the devastating clinical outcomes caused by hvKP infection. …”
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530
Mycoketide: A CD1c-Presented Antigen with Important Implications in Mycobacterial Infection
Published 2012-01-01“…Mycobacterium tuberculosis and related mycobacteria species are unique in that the acid-fast bacilli possess a highly lipid-rich cell wall that not simply confers resistance to treatment with acid alcohol, but also controls their survival and virulence. It has recently been established that a fraction of the cell wall lipid components of mycobacteria can function as antigens targeted by the acquired immunity of the host. …”
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531
Advancements in the development of antivirals against SARS-Coronavirus
Published 2025-01-01“…The existence of animal reservoirs of coronaviruses continues to pose a risk of re-emergence with improved fitness and virulence. Given the high death rate (up to 70 percent) and the high rate of severe sickness (up to 68.7 percent in long-COVID patients), it is even more critical to identify new therapies as soon as possible. …”
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532
Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk
Published 2013-01-01“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. …”
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533
Potential Usefulness of Streptococcus pneumoniae Extracellular Membrane Vesicles as Antibacterial Vaccines
Published 2017-01-01“…The EMVs of bacteria play important roles in their virulence, biogenesis mechanisms, and host cell interactions. …”
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534
Inflammasomes, Autophagy, and Cell Death: The Trinity of Innate Host Defense against Intracellular Bacteria
Published 2019-01-01“…Various pathogens produce virulence factors to control inflammasomes, subvert autophagy, and modulate host cell death in order to evade host defense. …”
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535
E. coli Sepsis: Red Flag for Colon Carcinoma—A Case Report and Review of the Literature
Published 2017-01-01“…E. coli strains B2 and D produce cyclomodulin toxins as part of their virulence, which interferes with the cell cycle regulation, promoting chromosomal instability, and increasing susceptibility to cancer. …”
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536
Pathogenic potential of ornithogenic <i>Escherichia coli</i> strains detected in the Earth's polar regions
Published 2024-12-01“…All strains studied were characterized by the presence of extensive virulence. Among the pathogenicity factors identified were haemolysins A, E, F, siderophores, including the yersiniabactin gene cluster, a number of adhesion, colonization and invasion factors, as well as the thermostable enterotoxin EAST-1 and genes that characterize enteroaggregative strains of E. coli (the virulence regulator gene eilA and enteroaggregative protein (air)). …”
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537
The transcriptional regulator Lrp activates the expression of genes involved in the biosynthesis of tilimycin and tilivalline enterotoxins in Klebsiella oxytoca
Published 2025-01-01“…The transcriptional regulator Lrp (leucine-responsive regulatory protein) controls the expression of several bacterial genes involved in virulence. In this work, we have uncovered novel findings that have significant implications. …”
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538
Accurate assembly of full-length consensus for viral quasispecies
Published 2025-02-01“…Reconstructing a robust consensus representation for these diverse mutant strains is essential for recognizing the genetic variations among strains and delving into aspects like virulence, pathogenesis, and selecting therapies. Virus genomes are typically small, often composed of only a few thousand to several hundred thousand nucleotides. …”
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539
Immune Response in H. pylori-Associated Gastritis and Gastric Cancer
Published 2020-01-01“…Some types of immune cells are recruited to enforce an antibacterial response, which could be impeded by H. pylori virulence factors with or without a specific immune cell. …”
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540
Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis
Published 2017-01-01“…Findings about pathogen metabolism can contribute to the identification of relationship between nitrate reductase and the C. pseudotuberculosis pathogenicity, virulence factors, and discovery of drug targets.…”
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