Healthcare-associated infections caused by Candida spp. in critical infants: a look at environmental surfaces by Priscila Guerino Vilela, Isadora Caixeta da Silveira Ferreira, Ralciane de Paula Menezes, Mário Paulo Amante Penatti, Reginaldo dos Santos Pedroso, Denise Von Dolinger de Brito Röder

“…Biofilm was the only virulence factor produced by all nine isolates. Molecular analysis revealed high similarity between one environmental isolate and one clinical isolate of C. parapsilosis sensu stricto. …”
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Temperature Depended Role of Shigella flexneri Invasion Plasmid on the Interaction with Acanthamoeba castellanii by Amir Saeed, David Johansson, Gunnar Sandström, Hadi Abd

“…Shigella flexneri is a Gram-negative bacterium causing the diarrhoeal disease shigellosis in humans. The virulence genes required for invasion are clustered on a large 220 kb plasmid encoding type three secretion system (TTSS) apparatus and virulence factors such as adhesions and invasion plasmid antigens (Ipa). …”
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LysR-Type Transcriptional Regulator VirR Responds to Temperature and pH and Directly Activates the Transcription of virS-Containing Operon in Rhodococcus equi by Tsutomu Kakuda, Takashi Sato, Mari Takuhara, Hirofumi Hagiuda, Yasunori Suzuki

“…Rhodococcus equi—a facultative intracellular pathogen of macrophages—causes bronchopneumonia in foals and patients who are immunocompromised. Virulent strains of R. equi possess a virulence-associated plasmid, which encodes a 15- to 17-kDa surface protein called virulence-associated protein A (VapA). …”
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Multidrug-resistant ST11-KL64 hypervirulent Klebsiella pneumoniae with multiple bla- genes isolated from children's blood by Rongmu Luo, Rongmu Luo, Guannan Ma, Qian Yu, Zhengqin Tian, Qihang Man, Xiangrong Shu, Xuetong Liu, Yupeng Shi, Lei Zhang, Jingbo Wang

“…Genomic analysis revealed that the IncHI1B/repB plasmid carried virulence factors (rmpA, ΔrmpA2, iucABCD, iutA), while IncFII/IncR and IncFII plasmids harbored resistance genes [blaCTX-M-65, blaTEM-1B, rmtB, blaSHV-12, blaKPC-2, qnrS1, blaLAP-2, sul2, dfrA14, tet(A), tet(R)]. …”
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Co-occurrence of entomopathogenic nematodes and earthworms enhances enduring biocontrol activity and microbial diversity in a naturalized plant-soil system by Maryam Chelkha, Rubén Blanco-Pérez, David Labarga, María de Toro, Jorge Dueñas-Hernani, Kyle Wickings, Raquel Campos-Herrera

“…Results showed no significant impact on plant growth. However, EPN virulence decreased after 30 days when applied alone but was maintained or enhanced when combined with EW or CEx. …”
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Association between clinical-biological characteristics of Klebsiella pneumoniae and 28-day mortality in patients with bloodstream infection by Xiaofeng Yu, Yi Zhao, Xiao Sun, Jiahui Luan, Haiyan Wang, Tianyu Sun, Tongtong Lin, Xia Zhou, Wei Yang, Ziguang Deng, Bo Liu, Hongyun Cao

“…Conclusion The carriage of virulence genes rfbA/B/D, which is responsible for the synthesis of O-antigen, was associated with poor prognosis of KP BSI. …”
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Acinetobacter baumannii represses type VI secretion system through a manganese-dependent small RNA-mediated regulation by Somok Bhowmik, Avik Pathak, Shivam Pandey, Kuldip Devnath, Abhiroop Sett, Nishant Jyoti, Timsy Bhando, Jawed Akhter, Saurabh Chugh, Ramandeep Singh, Tarun Kumar Sharma, Ranjana Pathania

“…Furthermore, the derivatives of pAB3 found in recent clinical isolates of A. baumannii harbor expanded antibiotic resistance genes and multiple determinants for virulence factors. Hence, the loss of this plasmid for T6SS activity renders A. baumannii T6+ cells susceptible to antibiotics and compromises their virulence. …”
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Adherence of Helicobacter pylori to the Gastric Mucosa by Marguerite Clyne, Brendan Drumm

“…The mechanism by which H pylori causes disease has not yet been elucidated but adherence to the gastric mucosa is thought to be an important virulence determinant of the organism. What is known about adherence of H pylori to the gastric mucosa is summarized. …”
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PB2 and PA mutations contribute to the pathogenicity of mouse-adapted pdmH1N1-Venus reporter influenza A virus in a mammalian model by Shixiang Wu, Ruonan Yi, Yingying Tao, Huimin Wu, Li Wu, Jiasheng Song, Xin Zhang, Beibei Yang, Xing Wu, Yulong He, Jianhong Shu, Huapeng Feng

“…Above all, we generated a mouse-adapted pdmH1N1 CA04-Venus virus with high virulence and stable green fluorescent Venus protein. …”
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Hypervirulent Klebsiella pneumoniae have better clinical outcomes than classical Klebsiella pneumoniae for lower respiratory tract infection patients by Xianxia Zhuo, Zichen Lei, Danni Pu, Yongli Wu, Jiankang Zhao, Bin Cao

“…All these strains underwent annotation for resistance and virulence factors, with 141 strains undergoing mouse infection experiments to assess their virulence. …”
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Nasopharyngeal carriage of Staphylococcus aureus in a rural population, Sierra Leone by Lisa Maria Kleine, Emmanuel Marx Kanu, Tobias Grebe, Desmond Mohamed Sesay, Henning Loismann, Maxwell Sesay, Tom Theiler, Viktoria Rudolf, Alexander Mellmann, Laura C. Kalkman, Martin P. Grobusch, Frieder Schaumburg

“…Isolates from colonization can therefore provide important information on virulence factors and antimicrobial resistance when data from clinical isolates are lacking. …”
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Distribution of sasX, mupA, and qacA/B genes and determination of genetic relatedness of epidemic methicillin-resistant Staphylococcus aureus strains associated with bloodstream in... by Rui Zhao, Bingyu Du, Lingling Hu, Chenxi Li, Fen Xue, Xing Wang, Changhong Jiang, Jinghua Wang, Yanfeng Zhao

“…IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) exhibits diverse genotypes with varying virulence and resistance profiles, particularly in the context of bloodstream infections (BSI). …”
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A comprehensive analysis of in vitro and in vivo genetic fitness of Pseudomonas aeruginosa using high-throughput sequencing of transposon libraries. by David Skurnik, Damien Roux, Hugues Aschard, Vincent Cattoir, Deborah Yoder-Himes, Stephen Lory, Gerald B Pier

“…During in vivo infection there were major losses of strains with Tn inserts in almost all known virulence factors, as well as respiration, energy utilization, ion pumps, nutritional genes and prophages. …”
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Lack of Outer Membrane Protein A Enhances the Release of Outer Membrane Vesicles and Survival of Vibrio cholerae and Suppresses Viability of Acanthamoeba castellanii by Soni Priya Valeru, Salah Shanan, Haifa Alossimi, Amir Saeed, Gunnar Sandström, Hadi Abd

“…It has been shown that V. cholerae expresses outer membrane proteins as virulence factors playing a role in the adherence to interacted host cells. …”
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An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH by Claire Healy, Sabine Ehrt, Alexandre Gouzy

“…We show that the virulence-associated inorganic phosphate (Pi) uptake system (Pst-1) regulates the ability of Mtb to replicate in acidic conditions. …”
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Examination of the Anaerobic Growth of Campylobacter concisus Strains by Hoyul Lee, Rena Ma, Michael C. Grimm, Stephen M. Riordan, Ruiting Lan, Ling Zhong, Mark Raftery, Li Zhang

“…C. concisus putative virulence proteins were identified using mass spectrometry analysis. …”
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Computational protocol for analyzing whole-genome sequencing data from Staphylococcus aureus clinical isolates by Miquel Sánchez-Osuna, Ivan Erill, Oriol Gasch, Oscar Q. Pich

“…Summary: Analyzing whole-genome sequencing (WGS) data from bacterial isolates is pivotal for understanding virulence and predicting clinical outcomes through association studies. …”
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Prevalence and Characterization of Streptococcus pyogenes Clinical Isolates from Different Hospitals and Clinics in Mansoura by Zeinab M. Helal, Dina E. Rizk, Mohamed M. Adel El-Sokkary, Ramadan Hassan

“…Different isolates were typed serotypically and genotypically by BOX-PCR. Different virulence factors were identified in S. pyogenes isolates. …”
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Priestia flexa as a Novel Urinary Tract Pathogen in Daloa, Côte d’Ivoire: Insights From Genomic Sequencing by Dého Aristide Gbégbé, Okran Beyosse Christophe Kacou, N’goran Parfait N’zi, Djédoux Maxime Angaman

“…On the other hand, two genes conferring resistance to beta-lactam and tetracyclines as well as nine virulence genes were predicted in the genome of 21LM367. …”
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Host-pathogen interaction in invasive Salmonellosis. by Hanna K de Jong, Chris M Parry, Tom van der Poll, W Joost Wiersinga

“…Plasmids also carry putative virulence-associated genes as well as those responsible for antimicrobial resistance. …”
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