-
341
The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies
Published 2025-02-01“…Specifically, increasing temperatures, changing precipitation patterns, and extreme weather events are influencing fungal growth, distribution, and virulence. These factors may expand the geographic range of pathogenic fungi, exposing populations to novel, potentially more virulent, or drug-resistant strains. …”
Get full text
Article -
342
Phenotypic and genotypic screening of multidrug resistant Klebsiella pneumoniae isolated from ready to eat street food in Tanta, Egypt
Published 2025-02-01“…Among ESBLs-encoding-genes, bla SHV was the most prevalent (71.4%) while bla TEM and bla CTX−M−2were equally-present (55.8%).The most prevalent virulence genes were mrkD (92.2%) followed by K2 (63.3%). …”
Get full text
Article -
343
Biofilm as a supracellular organization of pathogenic bacteria
Published 2024-12-01“…Bacteria use QS to regulate activities and behavior including competence, conjugation, symbiosis, virulence, motility, sporulation, antibiotic production and biofilm formation. …”
Get full text
Article -
344
Using In Silico Methods to Identify Protein Tyrosine Kinase A (PtkA) Homolog in Non-Tuberculous Mycobacteria (NTM)
Published 2024-11-01“…PtkA is a crucial protein tyrosine kinase that regulates bacterial growth, stress response, and virulence by phosphorylating various substrates in <i>Mtb</i>. …”
Get full text
Article -
345
Who arrived first? Priority effects on Candida albicans and Pseudomonas aeruginosa dual biofilms
Published 2025-02-01“…Consecutive colonization increases biofilm virulence and negates C. albicans’ protective effect on P. aeruginosa PAET1 against meropenem treatment. …”
Get full text
Article -
346
Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae
Published 2025-02-01“…Targeting the respective molecular interfaces, which are absent in human UGP, could provide a means of selectively inhibiting the bacterial virulence factor UGP and potentially rendering pathogenic species avirulent.IMPORTANCEThe enzyme uridine diphosphate-glucose pyrophosphorylase (UGP) is important for the virulence of bacterial pathogens and, therefore, a potential drug target. …”
Get full text
Article -
347
Fitness costs of Mycobacterium tuberculosis resistant to rifampicin is compensated by rapid Th2 polarization mediated by early and high IL-4 production during mice infection
Published 2025-01-01“…Abstract It was a general belief that drug resistance in Mycobacterium tuberculosis (Mtb) was associated with lesser virulence, particularly rifampicin resistance, which is usually produced by mutations in the RNA polymerase Beta subunit (RpoB). …”
Get full text
Article -
348
Genotypic and Phenotypic Characterizations of Methicillin-Resistant Staphylococcus aureus (MRSA) on Frequently Touched Sites from Public Hospitals in South Africa
Published 2021-01-01“…This study aimed to ascertain the prevalence, genetic relatedness, antibiotic resistance, and virulence profile of MRSA on some frequently touched hospital sites in South Africa. …”
Get full text
Article -
349
Une bactérie multirésistante avant l’ère des antibiotiques : l’agent de la mélioïdose
Published 2023-08-01“…These adaptation mechanisms are also the virulence factors that make melioidosis serious, in particular the efflux pumps that are the main support for its multi-resistance to antibiotics.…”
Get full text
Article -
350
Antibiotic Susceptibility Pattern and Biofilm Formation in Clinical Isolates of Enterococcus spp.
Published 2019-01-01“…It produces different virulence factors. Enterococcus surface protein (esp) is a virulence factor that helps in the adhesion, but its role in biofilm formation is still contradictory. …”
Get full text
Article -
351
Genotypic and Phenotypic Assessment of Hyaluronidase among Type Strains of a Select Group of Staphylococcal Species
Published 2009-01-01“…Hyaluronidases degrade hyaluronic acid, a major polysaccharide of the extracellular matrix of tissues, and are considered important for virulence in a number of Gram-positive and -negative bacteria. …”
Get full text
Article -
352
Incidence, Antibiotic Susceptibility and Characterization of Vibrio parahaemolyticus Isolated from Seafood in Selangor, Malaysia
Published 2021-09-01“…This study aims to investigate the presence of V. parahaemolyticus, their virulence, antibiotic profiles, and plasmid profiles from 77 different kinds of shellfish samples collected from wet markets and supermarkets in Selangor, Malaysia. …”
Get full text
Article -
353
Whole-genome sequencing-based characterization of Salmonella enterica Serovar Enteritidis and Kentucky isolated from laying hens in northwest of Iran, 2022–2023
Published 2025-01-01“…The presence of numerous virulence determinants, SPIs and ARGs in the examined NTS isolates poses a significant risk for food safety. …”
Get full text
Article -
354
Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis
Published 2025-01-01“…Iron uptake is a prerequisite for virulence and is strictly controlled by a global iron uptake regulator, Fur, which acts as a repressor under iron-replete conditions. …”
Get full text
Article -
355
Comparison of phenotypic and genetic traits of ESBL-producing UPEC strains causing recurrent or single episode UTI in postmenopausal women
Published 2025-02-01“…This study aims to characterize the virulence expression and intracellular persistence of ESBL-producing uropathogenic E. coli (E-UPEC) strains isolated from postmenopausal women with recurrent or single episode infections. …”
Get full text
Article -
356
Biochemical, ecological and molecular characterization of Xenorhabdus anantnagensis associated with Steinernema anantnagense from India: evaluating nematode efficacy against Helico...
Published 2025-01-01“…The nematode isolate KP_CU demonstrated high virulence against H. armigera larvae, with complete mortality achieved within 60 h across all tested inoculum levels. …”
Get full text
Article -
357
Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion.
Published 2017-01-01“…We also demonstrated lesser virulence of the natural mutant in the guinea pig animal model. …”
Get full text
Article -
358
A novel broad-spectrum bacteriophage cocktail against methicillin-resistant Staphylococcus aureus: Isolation, characterization, and therapeutic potential in a mastitis mouse model.
Published 2025-01-01“…In silico analyses have confirmed the absence of antimicrobial resistance or virulence factor-encoding genes within their genomes. …”
Get full text
Article -
359
Helicobacter pylori Pathogenicity Factors Related to Gastric Cancer
Published 2017-01-01“…Our results show an elevated prevalence of infection with H. pylori strains carrying known virulence genotypes with high genetic diversity. This highlights the importance of identifying gene variants for an early detection of virulent genotypes.…”
Get full text
Article -
360
Non-albicans Candida Infection: An Emerging Threat
Published 2014-01-01“…Fungi once considered as nonpathogenic or less virulent are now recognized as a primary cause of morbidity and mortality in immunocompromised and severely ill patients. …”
Get full text
Article