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261
Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease
Published 2024-12-01“…Dysfunctional autophagy has been implicated in the development of various diseases, including cancer, neurodegenerative disorders, metabolic diseases, and bacterial or viral infections. Recent studies have highlighted the dual role of autophagy in cancer: while it can act as a tumor suppressor in early stages, it may also support tumor cell survival in advanced stages. …”
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262
Clinical Feature of Intrahepatic B-Lymphocytes in Chronic Hepatitis B
Published 2014-01-01“…Humoral immunity constitutes major defense mechanism against viral infections. However, the association of hepatic injury and B-cells population in chronic hepatitis B virus (HBV) carriers has not been studied well. …”
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263
Development of a respiratory virus risk model with environmental data based on interpretable machine learning methods
Published 2025-02-01“…Abstract In recent years, numerous studies have explored the relationship between atmospheric conditions and respiratory viral infections. However, these investigations have faced certain limitations, such as the use of modestly sized datasets, a restricted geographical focus, and an emphasis on a limited number of respiratory pathogens. …”
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264
Impact of COVID-19 on metabolic parameters in patients with type 2 diabetes mellitus
Published 2025-02-01“…Abstract Background and aim The Coronavirus Disease 2019 (COVID-19) pandemic has disproportionately affected individuals with Type 2 Diabetes Mellitus (T2DM), making them more susceptible to viral infections. Additionally, COVID-19 and the associated lockdown restrictions have influenced metabolic regulatory mechanisms in this population. …”
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265
Influenza B virus infection alters the regenerative potential of murine alveolar type 2 pneumocytes
Published 2025-02-01“…The impact on the cells that survive viral infection in the distal lung epithelia, however, is much less well-characterized. …”
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266
Comparison of Two Field Deployable PCR Platforms for SARS-CoV-2 and Influenza A and B Viruses’ Detection
Published 2025-01-01“…Background: Respiratory viral infections are a major public health challenge and the most diagnosed medical condition, particularly for individuals living in close proximity, like military personnel. …”
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267
Pathogenicity of tick-derived lymphocytic choriomeningitis virus in BALB/c mice
Published 2025-01-01“…Conclusions This study furnishes significant insights into the pathogenic traits of the tick-derived LCMV strain JX14, thereby potentially providing a valuable in vivo research model for examining the immunological responses elicited by chronic viral infections.…”
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268
Recombinant short TNF-BD protein from smallpox virus is pharmacologically active in an experimental septic shock model
Published 2020-05-01“…Tumor necrosis factor (TNF) is one among the key cytokines that mediate the immune system to protect humans against viral infections. Throughout evolution, anthropogenic Variola virus (VARV) has developed effective mechanisms to overcome human defense reactions. …”
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269
Therapeutic applications of novel drug delivery systems of liquorice: An updated review on recent advancements
Published 2024-01-01“…It exhibits broad spectrum biological activities such as anti-inflammatory, immunomodulatory, anti-oxidant, anti-cancer, anti-diabetic, anti-microbial properties and is used in the treatment of different diseases such as cancer, inflammation, viral infections, cardiovascular and respiratory disorders. …”
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270
Distribution of potato mosaic viruses on plants of the <i>Petota</i> Dumort. section of <i>Solanum</i> L. in the VIR collection
Published 2023-07-01“…The VIR collection presents the diversity of the potato gene pool, including potato cultivars and related tuber-forming species. Diagnostics of viral infections in plants saved for several years by obtaining tuber reproductions is an important part of the work on the conservation and sustainable utilization of the potato gene pool. …”
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271
ENDOPROSTHESIS OF THE SHOULDER JOINT IN METASTATIC LESIONS OF THE PROXIMAL HUMERUS DURING IMMUNOSUPPRESSIVE THERAPY
Published 2017-03-01“…Complications associated with the continuous use of immunosuppressive therapy include bacterial and viral infections. It must be emphasized that in the context of immunosuppression bacterial infection is much greater and is accompanied by greater mortality than in patients without immunosuppression. …”
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272
TRIM8 inhibits porcine epidemic diarrhoea virus replication by targeting and ubiquitinately degrading the nucleocapsid protein
Published 2025-01-01“…Tripartite motif 8 (TRIM8) has been shown to play multiple roles in the host’s defence against viral infections. However, the functions of TRIM8 in regulating PEDV infection are still not well understood. …”
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273
Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections
Published 2024-12-01“…Cyclophilin (Cyp) inhibitors are of clinical interest in respect to their antiviral activities in the context of many viral infections including chronic hepatitis B and C. Cyps are a group of enzymes with peptidyl-prolyl isomerase activity (PPIase), known to be required for replication of diverse viruses including hepatitis B and C viruses (HBV and HCV). …”
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274
From thrombosis to tamponade: unveiling severe pericardial effusion in a misdiagnosis case
Published 2025-01-01“…Conclusion Patients with viral infections, specifically COVID-19, are at risk of undiagnosed severe pericardial effusions. …”
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275
Diagnostic ability of myxovirus resistance-A in pediatric cases of viral-acute respiratory tract infections with vitamin A and zinc deficiencies
Published 2025-03-01“…Myxovirus resistance-A (MxA) protein, selectively induced by the activation of type I interferon in response to viral infections, has emerged as a promising biomarker to diagnose viral ARTI. …”
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276
Molecular Evidence of Coinfection with Acute Respiratory Viruses and High Prevalence of SARS-CoV-2 among Patients Presenting Flu-Like Illness in Bukavu City, Democratic Republic of...
Published 2022-01-01“…The coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with clinical manifestation cases that are almost similar to those of common respiratory viral infections. This study determined the prevalence of SARS-CoV-2 and other acute respiratory viruses among patients with flu-like symptoms in Bukavu city, Democratic Republic of Congo. …”
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277
Detection of High- and Low-Risk HPV DNA in Archived Breast Carcinoma Tissues from Ethiopian Women
Published 2021-01-01“…Recently, a number of investigations have linked breast cancer to viral infections. High-risk HPV types, predominantly HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59, are established as carcinogens in humans. …”
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278
Herpes Simplex Virus Type 2 (HSV-2) and Cytomegalovirus (CMV) among Women with Macerated Stillbirth: A Cross-Sectional Hospital-Based Study from Mwanza, Tanzania
Published 2022-01-01“…Stillbirth adversely affects pregnancy outcomes in low- and middle-income countries (LMICs). Viral infections have been implicated as one of the causes of stillbirths. …”
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279
Clinical Activity of Behcet’s Disease Associated with SARS-CoV-2 and Herpes Simplex Virus: Insights from Three Case Reports
Published 2025-01-01“…Sekeloa Selatan No. 1, Bandung, West Java, 40132, Indonesia, Email irna.sufiawati@fkg.unpad.ac.idIntroduction: The Behçet’s Disease Current Activity Form (BDCAF) is crucial for monitoring the progression and treatment efficacy of Behçet’s Disease (BD), an autoimmune disorder that can be triggered or exacerbated by viral infections. Herpes simplex virus type 1 (HSV-1) has long been recognized as a potential trigger for BD, as it can induce systemic inflammation and exacerbate symptoms. …”
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280
Collapsing Pattern Class-IV Lupus Nephritis Presenting as Posterior Reversible Encephalopathy Syndrome and Cardiac Tamponade: A Rare COVID-19 Sequelae
Published 2025-01-01“…Numerous aetiologies have been proposed, including viral infections such as Human Immunodeficiency Virus (HIV), Cytomegalovirus (CMV), Epstein-Barr virus, and Parvovirus B19, as well as medications and acute ischaemia. …”
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