-
121
Intelligent diagnosis and prediction of pregnancy induced hypertension in obstetrics and gynecology teaching by integrating GA
Published 2025-02-01“…The objective of this model is to maximize the utility of medical data and enhance treatment quality.ResultsThe refined intelligent feature selection approach identified several significant indicators of pregnancy-related hypertension, such as phosphor dehydrogenase deficiency, body mass index, gestational urinary proteins, vascular endothelial growth factor receptor 1, placental growth factor, thalassemia, and a familial history of diabetes mellitus or hypertension. …”
Get full text
Article -
122
miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation
Published 2025-01-01“…The exposure of HUVECs to Ang-1, angiopoietin-2 (Ang-2), fibroblast growth factor 2 (FGF2), vascular endothelial growth factor (VEGF), or transforming growth factor β (TGFβ) triggers the regulation of PDRG1 expression. …”
Get full text
Article -
123
Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
Published 2025-02-01“…Several other abnormalities in endothelial and platelet activation were identified (including elevated soluble P-selectin, elevated von Willebrand factor, and elevated vascular endothelial growth factor) but these did not change with treatment or predict outcome. …”
Get full text
Article -
124
Neovascular age-related macular degeneration: disease pathogenesis and current state of molecular biomarkers predicting treatment response—a scoping review
Published 2024-05-01“…Age-related macular degeneration is a major cause of blindness, and the development of anti-vascular endothelial growth factor (VEGF) intravitreal treatments has revolutionised the management of the disease. …”
Get full text
Article -
125
Investigation of the Effects of Some Cardiovascular Drugs on Angiogenesis by Transgenic Zebrafish
Published 2023-01-01“…We found that 6 drugs including isosorbide mononitrate, amlodipine, bisoprolol fumarate, carvedilol, irbesartan, and rosuvastatin calcium may affect angiogenesis by vascular endothelial growth factor (VEGF) signaling pathway. Conclusion. …”
Get full text
Article -
126
The Role of Targeted Therapy in Metastatic Renal Cell Carcinoma
Published 2007-01-01“…The most clinically developed targeted therapies in advanced RCC are those that target the vascular endothelial growth factor (VEGF) ligand or receptor (VEGFR) and therapy directed against the mammalian target of rapamycin (mTOR). …”
Get full text
Article -
127
Modeling of chemo-radiotherapy targeting growing vascular tumors: A continuum-level approach.
Published 2025-01-01“…Our model integrates the impact of chemical species on tumor dynamics, and we model -through reaction-diffusion equations- the spatio-temporal evolution of oxygen, vascular endothelial growth factor (VEGF) and chemotherapeutic agents. …”
Get full text
Article -
128
Human Genetics of Diabetic Retinopathy: Current Perspectives
Published 2010-01-01“…Aside from evidence for a few genes including aldose reductase and vascular endothelial growth factor, the genetics of DR remain poorly elucidated. …”
Get full text
Article -
129
Management of Uveitis-Related Choroidal Neovascularization: From the Pathogenesis to the Therapy
Published 2014-01-01“…Its pathogenesis is supposed to be similar to the wet age related macular degeneration: hypoxia, release of vascular endothelial growth factor, stromal cell derived factor 1-alpha, and other mediators seem to be involved in the uveitis-related choroidal neovascularization. …”
Get full text
Article -
130
Is It Safe to Restart Antivascular Endothelial Growth Factor Therapy in Patients with Renal Cell Carcinoma after Cardiac Ischemia?
Published 2015-01-01“…Agents targeting vascular endothelial growth factor (VEGF) represent active drugs in treating patients with advanced renal cell carcinoma (RCC). …”
Get full text
Article -
131
Therapeutic Effect of Cu(II) Complex with Photocatalytic Property on Gastric Cancer by Inhibiting the Proliferation of Tumor Cells
Published 2022-01-01“…However, we also used real-time reverse transcription-polymerase chain reaction (RT-PCR) to detect the activation of vascular endothelial growth factor (VEGF) signaling pathway, and Cell Counting Kit-8 (CCK-8) method was used to calculate the inhibition activity of 1 on gastric cancer cell viability.…”
Get full text
Article -
132
Expression and Significances of Contactin-1 in Human Gastric Cancer
Published 2013-01-01“…This study aimed at determining the relationship between vascular endothelial growth factor-C (VEGF-C), vascular endothelial growth factor receptor-3 (VEGFR-3), and contactin-1 (CNTN-1) expression in gastric cancer (GC). …”
Get full text
Article -
133
Effect of intravitreal injections on the progression and prognosis of primary open-angle glaucoma
Published 2021-12-01“…</i> </p> <p> <i><b>Keywords</b>: intravitreal injections, glaucoma, vascular endothelial growth factor, retinal ganglionic cells, retinal nerve fiber layer, intraocular pressure, optical coherence tomography, optic disc.…”
Get full text
Article -
134
The Amelioration of Detrimental Biochemical Anomalies by Supplementing B, C, and E Vitamins in Subjects with Type 2 Diabetes Mellitus May Reduce the Rate of Development of Diabetic...
Published 2022-01-01“…In this prospective clinical trial, 185 patients with T2DM who received B vitamins, vitamin C, and vitamin E along with antidiabetic medication for five years demonstrated a slower rate of the development of DR and reduced abnormal biochemical mediators like reactive oxygen species (ROS), malondialdehyde (MDA), AGE, and vascular endothelial growth factor (VEGF) compared to 175 T2DM individuals who were treated with only antihyperglycemic drugs.…”
Get full text
Article -
135
Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment
Published 2025-02-01“…HIF-1α regulates critical pathways, including the expression of vascular endothelial growth factor and immune checkpoint upregulation, leading to tumor-infiltrating lymphocyte dysfunction and recruitment of immunosuppressive cells like regulatory T cells and myeloid-derived suppressor cells. …”
Get full text
Article -
136
Primary Congenital Lymphedema Complicated by Hydrops Fetalis: A Case Report and Review of the Literature
Published 2013-01-01“…Primary congenital lymphedema was confirmed via molecular testing of the vascular endothelial growth factor receptor-3 gene. Discussion. …”
Get full text
Article -
137
A Case Report with Severe Thrombocytopenia Induced by Axitinib
Published 2020-01-01“…Axitinib is an oral, second-generation tyrosine kinase inhibitor that is selective for vascular endothelial growth factor receptors (VEGFR). This agent is approved as monotherapy or in combination with immune checkpoint inhibitors for the treatment of metastatic renal cell carcinoma. …”
Get full text
Article -
138
Ultrastructural imaging biomarkers in diabetic macular edema: A major review
Published 2025-01-01“…Diabetic macular edema (DME) is a vision-threatening complication of diabetic retinopathy and causes significant morbidity in patients. Anti-vascular endothelial growth factor (VEGF) agents are the mainstay of treatment for DME, with steroid implants being used for the treatment of anti-VEGF resistant eyes. …”
Get full text
Article -
139
Intraoperative Imaging in Ovarian Cancer: Fact or Fiction?
Published 2011-07-01“…For clinical implementation, the five most prominent targets were identified: folate receptor α, vascular endothelial growth factor, epidermal growth factor receptor, chemokine receptor 4, and matrix metalloproteinase. …”
Get full text
Article -
140
3D-QSAR Study on a Series of VEGFR-2 Kinase Inhibitors: 3-Pyrrole Substituted Indolin-2-Ones Compounds
Published 2013-01-01“…The vascular endothelial growth factor receptor-2 kinases (VEGFR-2) are attractive targets for the development of anticancer agents. …”
Get full text
Article