Determining timeframes to death for imminently dying patients: a retrospective cohort study by Tricia O’Connor, Wai-Man Liu, Juliane Samara, Joanne Lewis, Karen Strickland, Catherine Paterson

“…Consequently, this necessitates a more accurate assessment of empirical data to better inform prognostication and reduce uncertainty around time until death. The aims of this study were to determine the timeframes for palliative care patients (a) between becoming comatose and death, and (b) between being totally dependent and bedfast, and then comatose, or death, using Australia-modified Karnofsky Performance Status (AKPS) scores. …”
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Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom by Lena Hubig, Anna-Katrine Sussex, Alasdair MacCulloch, Derralynn Hughes, Ryan Graham, Liz Morris, Syed Raza, Andrew J. Lloyd, Amanda Sowinski, Katy Gallop

“…The general public rated the health states consistently lower with increasing disease progression. There was greater uncertainty around utility estimates for the severe states, suggesting that participants found it harder to rate them. …”
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Global, regional, and national burden of ischemic heart disease attributable to secondhand smoke from 1990 to 2019 by Xinyue Yang, Zhiqiang Zhang, Jiayi Sun, Wenjuan Zhang

“…Central Asia has the highest ASMR (16 per 100000, 95% uncertainty interval, UI: 12.8–19.4), and Oceania has the highest ASDR (323.2 per 100000, 95% UI: 228.9–443.1 per 100000) in 2019. …”
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Impact of low-dose CT screening for lung cancer on ethnic health inequities in New Zealand: a cost-effectiveness analysis by Sue Crengle, Giorgi Kvizhinadze, Melissa McLeod, Peter Sandiford, Karen Bartholomew

“…Changes in inequities in lung cancer survival and ‘health-adjusted life expectancy’ (HALE) were measured.Results LDCT screening in NZ is likely to be cost-effective for the total population: NZ$34 400 per HALY gained (95% uncertainty interval NZ$27 500 to NZ$42 900) and for Māori separately (using a threshold of gross domestic product per capita NZ$45 000). …”
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Production of green steel from low-grade ores: An end-to-end techno-economic assessment by Alireza Rahbari, M. Shahabuddin, Shabnam Sabah, Geoffrey Brooks, John Pye

“…Summary: Hydrogen ironmaking is the most mature and advanced of the available green steel technologies, but uncertainty exists about its cost effectiveness with anything but the highest ore grades. …”
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Comparative Study of Fuel and Greenhouse Gas Consumption of a Hybrid Vehicle Compared to Spark Ignition Vehicles by Edgar Vicente Rojas-Reinoso, Michael Anacleto-Fernández, Jonathan Utreras-Alomoto, Carlos Carranco-Quiñonez, Carmen Mata

“…Five measurements were generated per route and for each vehicle tested to reduce uncertainty and strengthen the prediction model with a factor of less than 10%. …”
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Drought and flood risk mapping using a GIS-based multi-criteria decision method: A case of the Olifants Basin, South Africa by Luxon Nhamo, James Magidi, Sylvester Mpandeli, Onisimo Mutanga, Stanley Liphadzi, Tafadzwanashe Mabhaudhi

“…In this age of increasing climate risks and uncertainty, droughts and floods have become the most impactful extreme climate events accounting for about 80 % of loss of human life and 70 % of economic losses in sub-Saharan Africa alone. …”
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Evaluation of a pilot family planning educational seminar and subsequent attitudes towards family planning among Muslim communities in Tanzania. by Alexandra A Cordeiro, Hajirah Gumanneh, Aneth Nzali, Valencia J Lambert, Amina Yussuph, Albert Kihunrwa, Yassin Mchondo, Ramadhan Mtita, Hidaya Yahaya, Samuel E Kalluvya, Joyce Wamoyi, Mehrunisha Suleman, Jennifer A Downs, Agrey H Mwakisole

“…Evidence has demonstrated that uncertainty about compatibility with religious beliefs and limited health knowledge hinder uptake of family planning (FP), even among women who would like to prevent or delay childbearing. …”
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Assessing the robustness and implications of econometric estimates of climate sensitivity by Trude Storelvmo, Menghan Yuan, Thomas Leirvik, Kari Alterskjær, Peter C B Phillips, Chris Smith

“…We show that, within uncertainty, this method correctly diagnoses TCR from 20 CMIP6 ESMs if the same input variables are taken from the ESMs that are available from observations. …”
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Comparing the cost-benefit of breast cancer screening programs in rural and urban areas across four economic zones in China: a Markov modeling analysis by Dachuang Zhou, Kejia Zhou, Wenjuan Wang, Hanqiao Shao, Hongliu Zhang, Wenxi Tang

“…The main outcome measured was incremental net benefit (INB) and incremental cost-effectiveness ratio (ICER), with sensitivity analyses to assess uncertainty. Results Using a willingness-to-pay threshold of three times the local per capita Gross domestic product (GDP), the recommended strategies varied across regions. …”
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Determination of Electrolytes in Critical Illness Patients at Different pH Ranges: Whom Shall We Believe, the Blood Gas Analysis or the Laboratory Autoanalyzer? by Christopher Hohmann, Roman Pfister, Kathrin Kuhr, Julia Merkle, Julian Hinzmann, Guido Michels

“…However, there is still uncertainty regarding the convergence of the prementioned assays, and data about the comparability dependent on the pH value are still lacking. …”
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Comparison of Hydrus and iStent microinvasive glaucoma surgery implants in combination with phacoemulsification for treatment of open-angle glaucoma: systematic review and network... by Xiaoyu Wang, Rongrong Hu, Dongyu Guo, Nan Hong, Xiuyuan Xuan

“…Our findings might be of some uncertainty due to the limited included data. Further studies are needed to investigate whether our findings are robust, including high-quality RCTs to directly compare these MIGS devices.…”
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Professional Self-Determination and Professional Identity of Students-Teachers in the Conditions of Individualisation of Education by E. G. Belyakova, I. G. Zakharova

“…In the context of increasing transfessionalism of labour market and growing socio-economic uncertainty, modern students, including future teachers, should not only master the chosen specialty, but also be ready for meaningful entry into the profession. …”
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PFAS residue analysis in fish and fish feed by applying a modified QuEChERS method in combination with LC-HRMS detection by Ourania Koloka, Vasiliki Boti, Dimitra Hela, Triantafyllos Albanis, Ioannis Konstantinou

“…Matrix effect studies demonstrated low, and medium values and the method showed an acceptable expanded uncertainty of <57.66 %. Finally, the modified method was applied to analyze fish and fish feed samples from Greek aquaculture facilities. …”
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Impact of introducing transnasal endoscopy on expanding diagnostic endoscopy services by Nigel Trudgill, Hasan Haboubi, Jeff Turner, Laura Munglani, Tom Crosby, Ben Thomas Crosby, Karen Wright, Kay Charles, Wendy Evans, Megan Mathias, Stevie Davies, Badr Abdalla

“…It is better tolerated compared with standard transoral endoscopy (TOE) but is still rarely used as a diagnostic modality. There is still uncertainty about how well it performs against TOE in diagnostic ability, cost and efficiency.Methods We explored utilising TNE to deal with the growing demand for endoscopy. …”
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Interrogating green social prescribing in South Wales; A multi-stakeholder qualitative exploration. by Menna Brown, Katharine Sarah Aylett

“…Tension between varying stakeholders was also evident, often preceded, or complicated by funding discrepancies, competition, and uncertainty. Stakeholders demanded clarity regarding evaluation outcomes and benchmarking across the sector.…”
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Minimizing Seam Lines in UAV Multispectral Image Mosaics Utilizing Irradiance, Vignette, and BRDF by Hoyong Ahn, Chansol Kim, Seungchan Lim, Cheonggil Jin, Jinsu Kim, Chuluong Choi

“…The accuracy was verified through a validation flight. The radiance uncertainty at the seam line ranged from 3.00 to 5.26% in the 80% lap mode when using nine images around the CRT, and from 4.06 to 6.93% in the 50% lap mode when using all images with the CRT. …”
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Tell me y: anticipation of sex discrepancies in cell-free DNA testing due to maternal genetic abnormalities: a case report by Nuria Balaguer, Emilia Mateu-Brull, Jose Antonio Martínez-Conejero, Ana Cervero, Roser Navarro, Jorge Jiménez-Almazán, Miguel Milán

“…Sex discordance between cell-free DNA (cfDNA) testing and ultrasound examination is rare but can cause significant patient discomfort and uncertainty. Here, we present two clinical cases where a closer examination of raw sequencing data allowed us to anticipate possible discrepancies caused by the insertion of Y-chromosome regions into the maternal genome. …”
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A mixed method exploration of job morale of physicians working in public healthcare settings in Kazakhstan during the COVID-19 pandemic by Alina Kuandyk, Mariya Dmitriyeva, Nazerke Toleukhanova, Maev Conneely, Timur Suleimenov, Dauren Sarssenov, Raimzhan Mamytkhan, Madiyar Sakhayev, Arman Tleubergenov, Medet Toleubayev

“…Four themes emerged from the thematic analysis: (1) fear of uncertainty; (2) media scrutiny; (3) resurgence in appreciation; and (4) heightened sense of duty. …”
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Assisted Parkinsonism Diagnosis Using Multimodal MRI—The Role of Clinical Insights by Tobias Meindl, Alexander Hapfelmeier, Tobias Mantel, Angela Jochim, Jonas Deppe, Silke Zwirner, Jan S. Kirschke, Yong Li, Bernhard Haslinger

“…Individual predicted probabilities were visualized to address diagnostic uncertainty. Results Clinical diagnosis was accurately confirmed using machine learning models with only small differences when using imaging and clinical signs versus imaging variables only (expected multiclass AUC of 0.95 vs. 0.92). …”
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