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    WALDENSTRÖM MACROGLOBULINEMIA - A STATE-OF-THE-ART REVIEW: PART 1: EPIDEMIOLOGY, PATHOGENESIS, CLINICOPATHOLOGIC CHARACTERISTICS, DIFFERENTIAL DIAGNOSIS, RISK STRATIFICATION, AND C... by Michele Bibas, Shayna Sarosiek, Jorge J. Castillo

    Published 2024-06-01
    Subjects: “…Amyloidosis, Anemia, B cells, BCL2, Bruton tyrosine kinase, Bing-Neel syndrome, Bruton Tyrosine Kinase Inhibitors, Cryoglobulinemia, CXCR4, flow cytometry, hyperviscosity, lymphoplasmacytic lymphoma, MYD88, Waldenström Macroglobulinemia, Peripheral neuropathy.…”
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    Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia by Abhishek Abhishek, Jonathan A Cook, Helen M Parry, Anne Francis, Lelia Duley, Vicki S Barber, Paul Moss, Nicholas Peckham

    Published 2023-09-01
    “…This study aims to determine in patients with chronic lymphocytic leukaemia (CLL) if a 3-week pause in Bruton tyrosine kinase inhibitor therapy (BTKi) starting 1 week before delivery of SARS-CoV-2 vaccine booster, improves vaccine immune response when compared with continuation of BTKi.Methods and analysis An open-label, randomised controlled superiority trial will be conducted in haematology clinics in approximately 10 UK National Health Service (NHS) hospitals. …”
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