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7981
Prospective evaluation of the impact of repeated whole prison testing for hepatitis C
Published 2025-02-01Get full text
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7982
Molecular and spatial analysis of tertiary lymphoid structures in Sjogren’s syndrome
Published 2025-01-01Get full text
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7983
Risk factors of aspiration in neurocritical care patients with enteral nutrition (神经重症肠内营养支持患者误吸危险因素分析)
Published 2023-04-01Get full text
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A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells
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7992
Effectiveness of Electronic Quality Improvement Activities to Reduce Cardiovascular Disease Risk in People With Chronic Kidney Disease in General Practice: Cluster Randomized Trial...
Published 2025-02-01“…ConclusionsFHT harnesses the data stored within EMRs to translate guidelines into practice through quality improvement activities and active clinical decision support. …”
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7993
Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric...
Published 2025-02-01“…Our findings reveal that iron rapidly induces T. vaginalis phosphatidylinositol-4-phosphate 5-kinase (TvPI4P5K) translation followed by its degradation, while simultaneously activating TvArf220 binding, which facilitates TvPI4P5K localization to the plasma membrane for PIP2 production. …”
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Unveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility
Published 2025-01-01“…Post-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function. …”
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Subtyping Social Determinants of Health in the "All of Us" Program: Network Analysis and Visualization Study
Published 2025-02-01“…ConclusionsThis study identified SDoH subtypes that had statistically significant biclusteredness and replicability, each of which had significant associations with specific adverse health outcomes and with translational implications for targeted SDoH interventions and health care policies. …”
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7996
Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics
Published 2024-12-01“…GO analysis of DEGs showed enrichment in the molecular functions such as ubiquitin-like protein ligase binding, cellular components such as the nuclear speck and nuclear envelope, and biological processes such as the regulation of translation. KEGG pathway enrichment indicated that the DEGs between IPSDMs and PBDMs might be related to various intracellular pathogen infections.Conclusion·Human IPSDMs and PBDMs exhibit certain similarities and heterogeneity at the single-cell transcriptional level. …”
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Effectiveness and Safety of Preoperative Halo Gravity Traction-Assisted Posterior Spinal Fusion Surgery for Severe and Rigid Scoliosis: A Comparative Matched-Cohort Study
Published 2024-01-01“…However, there was no significant difference in the imaging parameters coronal vertical axis (CVA) and apical vertebral translation (AVT) between the two groups (P>0.05). In the preoperative surgical planning phase before HGT treatment, 26 patients were initially considered candidates for 3-column osteotomy (3CO), while one patient was evaluated as suitable for posterior column osteotomy (PCO). …”
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