Advances in the relationship between AP-1 and tumorigenesis, development and therapy resistance by Xinni Xue, Zhiwei Li, Jiahui Zhao, Ziyi Zhao, Zhihang Li, Yong Li, Yawen Liu, Huan He

“…Abstract Activating protein 1 (AP-1) is a transcription factor composed of several protein families, Jun proteins and Fos proteins are the components of AP-1. …”
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Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma by Mert Cihan, Greta Schmauck, Maximilian Sprang, Miguel A. Andrade-Navarro

“…The constructed networks of microRNA-transcription factor-target genes provide insights into the cellular mechanisms influencing cancer cell survival and therapeutic resistance. …”
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Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation by Vikas Nath, Mithra Baliga, Jack Lewin, Frederico Souza, Israh Akhtar

“…Immunohistochemistry revealed positivity for thyroglobulin and thyroid transcription factor 1, consistent with metastatic follicular thyroid carcinoma (FTC). …”
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Decreases in mRNA by an siRNA Complex Do not Alter Blood Pressure in Mice by Su-Min Ji, Young-Bin Shin, So-Yon Park, Hyeon-Ju Lee, Bermseok Oh

“…CASZ1 is a zinc finger transcription factor that controls apoptosis and cell fate and suppresses neuroblastoma tumor growth by reprogramming gene expression, like a tumor suppressor. …”
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Pax6 regulates neuronal migration and cell proliferation via interacting with Wnt3a during cortical development by Bichao Zhang, Meihua Hou, Jiayan Huang, Yunfei Liu, Ciqing Yang, Juntang Lin

“…Abstract The paired box 6 (Pax6) gene encodes a highly conserved transcription factor, involved in the development of eyes, brain, and endocrine glands. …”
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Biosynthesis of the Essential Fatty Acid Oxidation Cofactor Carnitine Is Stimulated in Heart and Liver after a Single Bout of Exercise in Mice by Tom L. Broderick, Frank A. Cusimano, Chelsea Carlson, Jeganathan Ramesh Babu

“…Liver and heart were removed under the same conditions for measurement of carnitine biosynthesis enzymes (liver butyrobetaine hydroxylase, γ-BBH; heart trimethyllysine dioxygenase, TMLD), organic cation transporter-2 (OCTN2, carnitine transporter), and liver peroxisome proliferator-activated receptor-alpha (PPARα, transcription factor for γ-BBH and OCTN2 synthesis). In exercised mice, FC levels in plasma decreased while heart and liver OCTN2 protein expressed increased, reflecting active uptake of FC. …”
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Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways by Antonia Cianciulli, Rosaria Salvatore, Chiara Porro, Teresa Trotta, Maria Antonietta Panaro

“…Inducible NO synthase (iNOS), nuclear transcription factor-kappa B (NF-κB) p65, MAPKs protein, and suppressors of cytokine signaling (SOCS)1 and SOCS3 were analyzed by western blotting. …”
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Explore the Role of the rs1801133-PPARG Pathway in the H-type Hypertension by Xiuwen Liang, Tingting He, Lihong Gao, Libo Wei, Di Rong, Yu Zhang, Yu Liu

“…Both rs1801133 mutation on Methylenetetrahydrofolate reductase (MTHFR) gene and transcription factor peroxisome proliferator-activated gamma (PPARG) have been associated with plasma homocysteine (Hcy) levels and hypertension. …”
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The Role of Bovine Amniotic Membrane and Hydroxyapatite for the Ridge Preservation by Octarina Octarina, Elly Munadziroh, Fathilah Abdul Razak, Ekowati Handharyani, Meircurius Dwi Condro Surboyo

“…The combination of bovine amniotic membrane and hydroxyapatite has shown promise as a scaffold material containing growth factors that can stimulate osteogenic-related factors such as bone morphogenetic protein 2 (BMP2), Runt-related transcription factor 2 (RUNX2), and osteocalcin. This stimulation leads to collagen production and osteoblast proliferation, resulting in new bone formation. …”
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Role of the Mucin-2 and Kaiso genes in the social behavior of mice by E. N. Kozhevnikova, K. M. Achasova, V. S. Korostina, E. B. Prokhortchouk, E. A. Litvinova

“…The Kaiso gene encodes a transcription factor that is expressed both in the brain and in the intestine. …”
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SOX5-Null Heterozygous Mutation in a Family with Adult-Onset Hyperkinesia and Behavioral Abnormalities by Michael Zech, Katharina Poustka, Sylvia Boesch, Riccardo Berutti, Tim M. Strom, Wolfgang Grisold, Werner Poewe, Juliane Winkelmann

“…SOX5 encodes a conserved transcription factor implicated in cell-fate decisions of the neural lineage. …”
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Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells. by Xiaowen Chen, Joanna Tober, Martin Dominguez, Alan T Tang, Jenna Bockman, Jisheng Yang, Sneha Mani, Chin Nien Lee, Mei Chen, Triloshan Thillaikumaran, Patricia Mericko-Ishizuka, Monica Mainigi, Nancy A Speck, Mark L Kahn

“…We found that the Runx1 transcription factor, which is required to generate HSPCs from HECs, is not expressed by mouse placental ECs. …”
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Comparative transcriptome analyses of different orthosiphon aristatus tissues reveal differentially expressed genes associated with flavonoid biosynthesis by Qiaoxue Wang, Huan Long, Shumeng Liu, Xixi Xu, Qin Zhang, Shanyong Yi

“…Additionally, 5,154 on average DEGs involved in flavonoid biosynthesis could be categorised into 58 transcription factor (TF) families. Among the identified DEGs, a total of 5,897 were common to all tissues, with 212 DEGs strongly associated with flavonoid accumulation in root. …”
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Ponatinib alleviates non-alcoholic steatohepatitis through TFEB-mediated autophagy by Zhuomiao Lin, Meiqing Yang, Xihui Yu, Guozhu Tan, Jiahong Zhong

“…We further discovered that the expression levels of LC3II and lysosomal associated membrane protein 1 (LAMP1) were reduced and the expression level of p62 was upregulated in both mouse and cell models, suggesting that autophagy was inhibited, which was restored by ponatinib treatment. In addition, transcription factor EB (TFEB) is a major regulator of autophagy and lysosome biogenesis and the transcription and protein expression levels of TFEB were decreased in steatosis hepatocytes, which could be ameliorated by ponatinib treatment.ConclusionThese results revealed that the beneficial effects of ponatinib on NASH via TFEB-mediated autophagy.…”
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STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells by Xiangyu Wang, Fengmian Wang, Zhi-Gang Zhang, Xiao-Mei Yang, Rong Zhang

“…STK3 promoted the migration of CD8+ T-cells by activating nuclear transcription factor κB (NF-κB) signaling. STK3 is a potential predictor of OC. …”
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Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells by Zeenath Unnisa, Kameshwar P. Singh, Ellen C. Henry, Catherine L. Donegan, John A. Bennett, Thomas A. Gasiewicz

“…The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor belonging to the Per-Arnt-Sim (PAS) family of proteins. …”
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Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene by Mina Zahiri, Maryam Hassanlou, Amir-Reza Javanmard, Nooshin Bijari

“…Krüppel-like factor 4 (KLF4) is a transcription factor that has different regulatory functions, and it plays a role in various cellular processes. …”
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Bioinformatics analysis of miR-2861 and miR-5011-5p that function as potential tumor suppressors in colorectal carcinogenesis by Alper Aytekin, Hikmet Kadakal, Deniz Mihcioglu, Turkan Gurer

“…The GO and KEGG pathway analysis showed that miR-2861 and miR-5011-5p may participate in multiple the biological process, cellular components, and molecular function subcategories such as mitotic cell cycle, regulation of small GTPase mediated signal transduction, cell death, and acid binding transcription factor activity. It was also revealed that target genes of miRNAs can be found in signaling pathways such as TGF-beta, Rap1, Ras, cAMP, Wnt, mTOR and, PI3K-Akt signaling pathways. …”
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The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases by Lingyi Yang, Shuli Chen, Qiuyu Zhao, Ying Sun, Hong Nie

“…The transcription factor Bach2 which is predominantly expressed in B and T lymphocytes represses the expression of genes by forming heterodimers with small Maf and Batf proteins and binding to the corresponding sequence on the DNA. …”
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Antitumor Activities of Aqueous Cinnamon Extract on 5637 Cell Line of Bladder Cancer through Glycolytic Pathway by Zeynab Aminzadeh, Nasrin Ziamajidi, Roghayeh Abbasalipourkabir, Sajedeh Daei, Sobhan Helbi, Abbas Moridnia

“…For evaluating of aqueous extract of Cinnamon effect on glycolysis, the gene expression of epidermal growth factor receptor 2 (ErbB2), heat shock protein transcription factor1 (HSF1), and lactate dehydrogenase A (LDHA), as well as protein levels of HSF1 and LDHA, LDH activity, glucose consumption, and lactate production, were measured. …”
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