Varroa Volatiles Offer Chemical Cues to Honey Bees for Initial Parasitic Recognition by Qinglong Zhao, Xinning Wang, Ahsan Mustafa, Ying Wang, Hongfang Wang, Xuepeng Chi, Baohua Xu, Zhenguo Liu

“…Olfaction mediated by the antennae is a vital sensory modality for arthropods and could be applied as a tool in pest control. The ectoparasitic mite <i>Varroa destructor</i> poses a significant threat to the health of the honey bee <i>Apis mellifera</i> worldwide and has garnered global attention. …”
Get full text

Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…Risk of bias will be assessed using the Risk of Bias 2 tool, and the quality of evidence will be evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation approach.Ethics and dissemination As this review involves secondary analysis of previously published data, ethical approval is not required. …”
Get full text

Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve... by Jay Patel, Priya Bhavsar, Harsh Shah, Sandul Yasobant, Deepak Saxena, Anish Sinha, Somen Saha, Yogesh Patel

“…A semi-structured questionnaire tool was used to collect socio-demographic, clinical, and ADR-related data from the TB patients. …”
Get full text

A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine by Deepa J. Arachchillage, Golzar Mobayen, Mike Laffan, Anna M. Randi, Josefin Ahnström, Charis Pericleous

“…Conclusion: We provide detailed optimization of a robust in vitro model to assess the induction of an inflammation-driven endothelial prothrombotic phenotype that is also sensitive to immunomodulatory therapies, providing a tool for investigating mechanisms of disease and new drugs.…”
Get full text

Regular human insulins versus rapid-acting insulin analogues in children and adolescents with type 1 diabetes: a protocol for a systematic review with meta-analysis and Trial Seque... by Johanne Juul Petersen, Sophie Juul, Caroline Barkholt Kamp, Pascal Faltermeier, Christina Dam Bjerregaard Sillassen, Tiago Jeronimo Dos Santos, Janus Christian Jakobsen

“…Risk of bias will be assessed with the Cochrane Risk of Bias tool—version 2, an eight-step procedure will be used to assess if the thresholds for clinical significance are crossed, and the certainty of the evidence will be assessed by Grading of Recommendations, Assessment, Development and Evaluations (GRADE). …”
Get full text

Diagnostic Accuracy of Procalcitonin for Bacterial Infection in Liver Failure: A Meta-Analysis by Xinchun He, Liang Chen, Haiou Chen, Yuqing Feng, Baining Zhu, Caixia Yang

“…The quality of the studies was evaluated using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. Heterogeneity, pooled diagnostic odds ratio (DOR), pooled sensitivity, pooled specificity, pooled positive likelihood ratio, pooled negative likelihood ratio, the area under the summary receiver operating characteristic curve (SROC), and metaregression analysis were performed using Stata16.0 software. …”
Get full text

Construction and Validation of a Major Depression Risk Predictive Model for Patients with Coronary Heart Disease: Insights from NHANES 2005–2018 by Li-xiang Zhang, Shan-bing Hou, Fang-fang Zhao, Ting-ting Wang, Ying Jiang, Xiao-juan Zhou, Jiao-yu Cao

“…A weighted logistic regression model was applied to construct and validate a nomogram-based prediction tool for major depression in this population. …”
Get full text

Correlation between the white blood cell/platelet ratio and 28-day all-cause mortality in cardiac arrest patients: a retrospective cohort study based on machine learning by Huai Huang, Guangqin Ren, Shanghui Sun, Zhi Li, Yongtian Zheng, Lijuan Dong, Shaoliang Zhu, Xiaosheng Zhu, Wenyu Jiang

“…Key patient characteristics, encompassing demographic data, comorbidities, hematological and biochemical indices, and vital signs, were extracted using PostgreSQL Administration Tool (pgAdmin) software. The Cox proportional hazards model assessed the impact of WPR on mortality outcomes, while Kaplan-Meier survival curves and restricted cubic spline (RCS) analysis further validated the findings. …”
Get full text

Genetic investigations of autosomal recessive inherited ichthyosis impressed by fetal ultrasound: Exome sequencing and haplotype linkage analysis by Ting-Yu Chang, Zhu Wei Lim, Yi-Tzu Chu, Wan-Ju Wu, Mei-Hui Lee, Shun-Ping Chang, Dong-Jay Lee, Wen-Hsiang Lin, Ming Ho, Jin-Chung Shih, Gwo-Chin Ma, Ming Chen

“…Results: WES identified pathogenic mutations in ABCA12 gene in both fetuses. Genome Analysis ToolKit (GATK 4 version 4.2.1.0) was merged using a setting of the trio model for exome variation analysis. …”
Get full text

Mobile application adjunct to the WHO basic emergency care course: a mixed methods study by Juma A Mfinanga, Hendry R Sawe, Anya L Greenberg, Andrea G Tenner, Alexandra Friedman, Paulina Nicholaus, Christian C Rose, Newton Addo, Catherine Reuben Shari, Upendo N George, Michael J Losak

“…We assessed whether a mobile application adjunct (BEC app) can have positive impact on knowledge acquisition and retention compared with the BEC course alone and evaluated perceptions, acceptability and barriers to adoption of such a tool.Design Mixed-methods prospective cohort study.Participants Adult healthcare workers in six health facilities in Tanzania who enrolled in the BEC course and were divided into the control arm (BEC course) or the intervention arm (BEC course plus BEC app).Main outcome measures Changes in knowledge assessment scores, self-efficacy and perceptions of BEC app.Results 92 enrolees, 46 (50%) in each arm, completed the BEC course. 71 (77%) returned for the 4-month follow-up. …”
Get full text

Wildlife policy, the food system and One Health: a complex systems analysis of unintended consequences for the prevention of emerging zoonoses in China, the Democratic Republic of... by Zhuoyu Wang, Tarra L Penney, Mala Ali Mapatano, Chloe Clifford Astbury, Janielle Clarke, Kathleen Chelsea Togño, Shital Desai, Anastassia Demeshko, Russel Aguilar, Angran Li, Zhilei Shi, Cary Wu, Marc K Yambayamba, Hélène Carabin, Valentina De Leon, Eduardo Gallo-Cajiao, Kirsten Melissa Lee, Krishihan Sivapragasam, Mary Wiktorowicz

“…We analysed these CLDs using the ‘fixes that fail’ (FTF) systems archetype, a conceptual tool used to understand and communicate how system adaptation can lead to policy failure. …”
Get full text

Correlation between Therapeutic Efficacy of CD34+ Cell Treatment and Directed In Vivo Angiogenesis in Patients with End-Stage Diffuse Coronary Artery Disease by Tien-Hung Huang, Cheuk-Kwan Sun, Yi-Ling Chen, Pei-Hsun Sung, Chi-Hsiang Chu, Mel S. Lee, Yuan-Ping Lin, Hon-Kan Yip, Fan-Yen Lee

“…We proposed that DIVAA may be a reliable tool for assessing coronary vascularization after CD34+ cell treatment.…”
Get full text

Design and Construction of an Aquaponics System: A Sustainable Approach to Enhancing Local Food Security in Offa, Nigeria by Rofiat Bunmi Mudashiru, Maryam Yusuf-Olawuyi, Aliyu Tijani, Lateef Umar, Francis Okeke, Oluwabunmi Adeyemi, Ismaila Amototo, Fatai Salaudeen

“…The result of the study can be applied as a guide to designing and building an effective aquaponics system and a tool for developing systems that can reduce food insecurity and farming techniques. …”
Get full text

Dataset of microscale atmospheric flow and pollutant concentration large-eddy simulations for varying mesoscale meteorological forcing in an idealized urban environmentZenodo by Eliott Lumet, Thomas Jaravel, Mélanie C. Rochoux

“…Computational Fluid Dynamics (CFD) has emerged as a powerful tool to address this challenge by providing obstacle-resolved flow and dispersion predictions. …”
Get full text

The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis by Lei Liu, Shufu Hou, Aiping Zhu, Bing Yan, Linchuan Li, Dandan Song

“…Therefore, ctDNA can serve as a diagnostic and stratification tool prior to treatment, as well as an effective indicator for monitoring treatment response and disease progression.Systematic Review Registrationwww.inplasy.com, identifier INPLASY2024110018.…”
Get full text

Nailfold Capillaroscopy in Early Stages of Mixed Connective Tissue Disease in a Sample of Egyptian Patients by Yasser A Elmotaleb Gazar, Hesham Salah Hamoud, Sherif Mohamed Ismail

“…Nailfold capillaroscopy (NFC) is a noninvasive diagnostic tool for patients with different connective tissue diseases that permit detection of local microvascular changes that correlate with systemic vascular involvement. …”
Get full text

Aplikasi Jurnal Harian Covid-19 untuk Pemantauan Isolasi Mandiri (PISOM) by Mutiara Anggun, Margaretha Amanda, Tri Ahmad Sandi, Rinto Priambodo

“…This application is tested with Usability Testing using the System Usability Scale (SUS) method, assessment result for this application is at Grade B, in this case the PISOM application can be used as a supporting tool to help health workers monitor Covid-19 patients who are self-isolating at home. …”
Get full text

Functional and effective EEG connectivity patterns in Alzheimer’s disease and mild cognitive impairment: a systematic review by Elizabeth R. Paitel, Christian B. D. Otteman, Mary C. Polking, Henry J. Licht, Kristy A. Nielson, Kristy A. Nielson

“…In AD, greater connectivity was most common during rest, suggesting compensatory resources during task engagement may already be exhausted.ConclusionThe review highlighted EEG connectivity as a powerful tool to advance understanding of AD-related changes in brain communication. …”
Get full text

The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review by Thiago Henrique Teodoro, Katerine Palharini Manfrin Costa, Jonato Prestes, José Campanholi, James Navalta, Guilherme Borges Pereira

“…The quality of the selected studies was assessed using the Cochrane risk of bias tool (ROB2), with data organized and presented in tables and figures.ResultsFourteen studies with 525 participants were included in the analysis. …”
Get full text

Loading rate, geometry, and damage state influence vertical extraction biomechanics in an ex vivo swine dental model by Timothy J. Gadzella, Karyne N. Rabey, Michael R. Doschak, Lindsey Westover, Owen Addison, Owen Addison, Dan L. Romanyk, Dan L. Romanyk

“…The results of these experiments suggest that the axisymmetric FEA model is a powerful tool for predicting a range of conditions and dental complex geometries. …”
Get full text