Assessment of Antibiotic Resistance and Efflux Pump Gene Expression in Neisseria Gonorrhoeae Isolates from South Africa by Quantitative Real-Time PCR and Regression Analysis by Nireshni Mitchev, Ravesh Singh, Veron Ramsuran, Arshad Ismail, Mushal Allam, Stanford Kwenda, Florah Mnyameni, Nigel Garrett, Khine Swe Swe-Han, Abraham J. Niehaus, Koleka P. Mlisana

“…This real-time qPCR approach, with few targets, can be further investigated for use as a potentially cost-effective diagnostic tool to detect resistance.…”
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Association of the Preoperative Controlling Nutritional Status (CONUT) Score with Clinicopathological Characteristics in Patients with Papillary Thyroid Carcinoma by Doohwa Kim, Myungsoo Im, Soree Ryang, Mijin Kim, Yun Kyung Jeon, Sang Soo Kim, Bo Hyun Kim

“…Background The Controlling Nutritional Status (CONUT) score is an immunonutritional test tool based on serum albumin, total cholesterol, and lymphocyte counts. …”
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Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation by Talke F. zur Bruegge, Andrea Liese, Sören Donath, Stefan Kalies, Maike Kosanke, Oliver Dittrich-Breiholz, Sandra Czech, Verena N. Bauer, André Bleich, Manuela Buettner

“…Taken together, our findings demonstrate that organoid culture, if standardized, constitutes a good tool for reducing the need for animal experiments and might further improve our understanding of, for example, the role of epithelial cells in inflammatory bowel disease development.…”
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The accuracy of an Online Sequential Extreme Learning Machine in detecting voice pathology using the Malaysian Voice Pathology Database by Nur Ain Nabila Za’im, Fahad Taha AL-Dhief, Mawaddah Azman, Majid Razaq Mohamed Alsemawi, Nurul Mu′azzah Abdul Latiff, Marina Mat Baki

“…Hence, it is a promising artificial intelligence that supports an online application to be used as a screening tool to encourage people to seek medical consultation early for a definitive diagnosis of voice pathology.…”
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Subacromial Pain Syndrome in Breast Cancer Survivors—Are Structural Shoulder Changes Verified by Ultrasound Clinically Relevant? by Ivana Klarić-Kukuz, Jure Aljinović, Blaž Barun, Marko Roki, Benjamin Benzon, Danijela Budimir Mršić, Maja Marinović Guić, Ana Poljičanin

“…Ultrasound is a valuable tool for detecting rotator cuff changes aiding in timely diagnosis of subacromial pain syndrome. …”
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The relationship between the living lab approach and successful implementation of healthcare innovations: an integrative review by Sylvia J van der Burg-Vermeulen, Nina Zipfel, Carel T J Hulshof, Angela G E M de Boer, Bedra Horreh

“…Quality was assessed based on a tool developed by Hawker et al.Results Of the 1173 retrieved articles, 30 studies were included of which 11 of high quality. …”
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Isolation, Identification, and Pathogenicity of Potential Probiotics Isolated from Intestinal Coconut Crab (Birgus latro Linnaeus, 1767) by Muhammad Aris, Tamrin Tamrin, Waode Munaeni, Sudirto Malan, Juharni Juharni, Rusmawati Labenua

“…Molecular identification was performed with sequencing and then analyzed using the Basic Local Alignment Search Tool (BLAST). The selection of isolates from the gastrointestinal tract of coconut crabs showed that the bacteria obtained were Enterobacter tabaci (BL1), Enterobacter hormaechei (BL2), Bacillus horneckiae (BL3), Pseudomonas stutzeri (BL4), and Acinetobacter variabilis (BL5). …”
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Postoperative Harris Hip Score Versus Harris Hip Score Difference in Hip Replacement: What to Report? by Nikolai Ramadanov, Maximilian Voss, Robert Hable, Hassan Tarek Hakam, Robert Prill, Mikhail Salzmann, Dobromir Dimitrov, Roland Becker

“…The Harris Hip Score (HHS) is the most widely used tool for measuring hip function and, in particular, the outcomes of hip surgery. …”
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Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review by Stéphane Cullati, Anita van Zwieten, Catherine Sherrington, Fiona M Blyth, Saman Khalatbari-Soltani, Marcia R Franco, Frerik Smit

“…Using a modified Quality in Prognosis Studies (QUIPS) tool, the risk of bias of included studies will be assessed by one reviewer with 20% of studies also independently appraised by a second reviewer. …”
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Evaluation of learning from Practical Obstetric Multi-Professional Training and its impact on patient outcomes in Australia using Kirkpatrick’s framework: a mixed methods study by Philip DeKoninck, Euan M Wallace, Debra Nestel, Arunaz Kumar, Sam Sturrock, Donna Lucey, Sally Stoyles, Jenny Morgan, Peter Neil, Michelle Schlipalius

“…We explored participants’ acquisition of knowledge and skills, its impact on clinical outcomes and organisational change to integrate the PROMPT programme as a credentialing tool. We also aimed to assess participants’ perception of usefulness of PROMPT in their clinical practice.Study design Mixed methods approach with a pre-test/post-test design.Setting Healthcare network providing obstetric care in Victoria, Australia.Participants Medical and midwifery staff attending PROMPT between 2013 and 2015 (n=508); clinical outcomes were evaluated in two cohorts: 2011–2012 (n=15 361 births) and 2014–2015 (n=12 388 births).Intervention Attendance of the PROMPT programme, a simulation programme taught in multidisciplinary teams to facilitate teaching emergency obstetric skills.Main outcome measure Clinical outcomes compared before and after embedding PROMPT in educational practice.Secondary outcome measure Assessment of knowledge gained by participants through a qualitative analysis and description of process of embedding PROMPT in educational practice.Results There was a change in the management of postpartum haemorrhage by early recognition and intervention. …”
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FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression by Sama Rezasoltani, Elahe Shams, Moein Piroozkhah, Yaser Aidi, Mehdi Azizmohammad Looha, Parmida Bagheri, Roudabeh Behzadi Andouhjerdi, Amir Sadeghi, Leili Rejali, Ehsan Nazemalhosseini-Mojarad

“…The Bioinformatics and Evolutionary Genomics web tool was employed to intersect the sets of shared microRNAs and their common targets. …”
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Design, implementation and evaluation of OSPE exam to evaluate the competence of occupational health and safety engineering students by Samira Rahimnejad, Kamaladdin Abedi, Farough Mohammadian, Ebrahim Darvishi, Ebrahim Mohammadi, Farzaneh Zarei, Madjid Shafiiyan

“…It seems that much more studies should be carried out in the field of health sciences especially regarding exam design and standard scenario writing methods, in order to judge its validity and reliability as an evaluation tool. At the same time, using OSPE as a supplement to traditional exams is very valuable.…”
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Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis by Jens Ivar Brox, Christopher James Rose, Anners Lerdal, Øystein Skare, Unni Olsen, Maren Falch Lindberg, Eva Marie-Louise Denison, Caryl Lynn Gay, Arild Aamodt, Ove Furnes, Kathryn A Lee

“…Blinded assessment with consensus agreement will be applied for inclusion of studies, data extraction and assessment of bias risk (Quality in Prognosis Studies tool). The co-primary outcomes, pain and impaired function, at 12 months after TKA will be analysed separately. …”
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Optimization of the Formulation of Rice Biscuits Supplemented with D. Edulis (L.) Powder Using Response Surface Methodology by Eliane Flore Eyenga, Hippolyte Tene Mouafo, Mercy Bih Loh Achu, Wilfred F. Mbacham, Sali Atanga Ndindeng

“…For this, statistical models were developed, validated, and optimized using the response surface methodology with the Doehlert design as a tool. The results showed that an increase in the substitution rate of margarine with of D. edulis powder enhanced the aroma while the substitution of refined wheat flour with rice flour led to an improvement of the overall quality of the biscuits. …”
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Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments by Amit Verma, Vikas Pandey, Catherine Sherry, Taylor Humphrey, Christopher James, Kailie Matteson, Jason T. Smith, Alena Rudkouskaya, Xavier Intes, Margarida Barroso

“…The study demonstrates that FLI is a powerful analytical tool to monitor the delivery of antibodydrugs both in cell cultures and in vivo live systems. …”
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Intelligent physiological signal infosecurity: Case study in photoplethysmography (PPG) signal by Chia‐Hung Lin, Jian‐Xing Wu, Neng‐Sheng Pai, Pi‐Yun Chen, Chien‐Ming Li, Ching Chou Pai

“…Abstract A wrist‐based photoplethysmography (PPG) tool offers a simple and non‐invasive approach for applications in vital sign monitoring and healthcare. …”
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Web-based interventions for pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis protocol by Ping Xu, Wei Zhang, Xiaojuan Wang, Dan Dan Chen, Pingping Guo, Yin Jin, Zhenzhen Xiang, Minna Mao, Qiong Zheng, Suwen Feng

“…The methodological quality of included studies will be assessed using the Effective Public Health Practice Project assessment tool. The overall meta-analyses for each of the interested outcomes will be performed if the outcome data are sufficient and provides similar effect measures, as well as subgroup analyses for glycaemic control indicators based on the different types of intervention format, interactivity and technology. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

“…The Cochrane Collaboration assessment tool was employed to evaluate the risk of bias in the included studies. …”
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Assessment of risk communication and community engagement interventions during the Marburg virus disease outbreak in Kagera region, Northwestern Tanzania by Mololo Noah Mwanjala, Emmanuel Mnkeni, Mikidadi Issanudia Mtalika, Marcelina Mponela, Atuganile Musyani, George Mrema, Amour Seleman, Catherine Gitige, Kokuhabwa Mukurasi, Gloria Macha, Hussein Mohamed, Pius Horumpende, Leopord Sibomana Leonard, Jonathan Mcharo, Wangeci Gatei, Salum Manyatta

“…Data were collected using a structured questionnaire developed using the WHO COVID-19 RCCE Rapid Quantitative Assessment Tool. Descriptive analysis was conducted using Microsoft Excel 2021. …”
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Identification and validation of diagnostic genes IFI44 and IRF9 in insomnia-associated autoimmune uveitis by Chao Wu, Hui Feng, Meng Tian, Baorui Chu, Xianyang Liu, Shuhao Zeng, Yakun Wang, Hong Wang, Shengping Hou, Qingfeng Liang

“…We investigated insomnia-associated genes that may contribute to AU pathogenesis and sought to identify potential biomarkers for insomnia-associated AU.MethodsMicroarray data related to insomnia and AU were downloaded from the Gene Expression Omnibus (GEO) database and analyzed. The GEO2R tool was used to identify differentially expressed genes (DEGs) that were common between insomnia and AU. …”
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