Uncovering potential causal genes for undiagnosed congenital anomalies using an in-house pipeline for trio-based whole-genome sequencing by Jeong-Min Kim, Hye-Won Cho, Dong Mun Shin, Oc-Hee Kim, Jihyun Kim, Hyeji Lee, Gang-Hee Lee, Joon-Yong An, Misun Yang, Heui Seung Jo, Ja-Hyun Jang, Yun Sil Chang, Hyun-Young Park, Mi-Hyun Park

“…Conclusions Taken together, the in-house pipeline established in this study provides a highly valuable diagnostic tool for the identification of potential candidate variants in patients with CA. …”
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Visual Mapping of Operating Theater Team Dynamics and Communication for Reflexive Feedback and Surgical Practice Optimization by Surya Surendran, MA, Candice Bonaconsa, MSc, Vrinda Nampoothiri, PharmD, Oluchi Mbamalu, PhD, Anu George, PGDip, Swetha Mallick, MCh, Sudheer OV, MCh, Alison Holmes, MD, Marc Mendelson, PhD, Sanjeev Singh, PhD, Gabriel Birgand, PhD, Esmita Charani, PhD

“…Data were gathered from adult gastrointestinal surgical teams at a tertiary hospital in India using observations, sociograms (communication mapping tool), and focus group discussions (FGDs). Our methods aimed to map team communication, roles and responsibilities in infection-related practices, and door openings. …”
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Beyond averaging: A transformer approach to decoding event related brain potentials by Philipp Zelger, Manuel Arnold, Sonja Rossi, Josef Seebacher, Franz Muigg, Simone Graf, Antonio Rodríguez-Sánchez

“…The attention maps above all showed a focus on the time window around 150 to 200 ms, where the average based analysis did not indicate relevant potentials.Employing these attention maps, we were able to gain new perspectives on the ERPs, discovering the attention maps potential as a tool for delving deeper into the analysis of event-related potentials.…”
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Evaluation of ChatGPT-4 for the detection of surgical site infections from electronic health records after colorectal surgery: A pilot diagnostic accuracy study by Josep M. Badia, Daniel Casanova-Portoles, Estela Membrilla, Carles Rubiés, Miquel Pujol, Joan Sancho

“…It appears to be a useful tool for initial screenings and for reducing manual review workload. …”
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Azospirillum brasilense and organomineral fertilizer co-inoculated with Bradyrhizobium japonicumon oxidative stress in soybean by Fernanda Barros, Reginaldo de Camargo, Regina Maria Lana, Miguel Henrique Franco, Mayara Cristiana Stanger, Vanderley José Pereira, Ernane Lemes

“…The use of organomineral fertilizers is a promising crop management tool made from the mixing of an organic source and mineral fertilizers. …”
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Chemical Fingerprint Analysis for Discovering Markers and Identifying Saussurea involucrata by HPLC Coupled with OPLS-DA by Qingdong Ma, Xiaoxiang Chen, Ke Zhang, Dahong Yao, Lu Yang, Hangyu Wang, Santai Bulemasi, Jian Huang, Jinhui Wang

“…Collectively, the chromatographic fingerprint of S. involucrata can be an effective and integrated method for the identification of authentic herbs from adulterant species or related plants, and discrimination of its different haplotypes provides an objective and reliable tool for quality control.…”
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Developing a machine learning model for predicting varicocelectomy outcomes: a pilot study by Coşkun Kaya, Mehmet Erhan Aydın, Özer Çelik, Aykut Aykaç, Mustafa Sungur

“…ML models could be identified as a new prediction tool for selecting the patients who will benefit from varicocelectomy. …”
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Development and validation of a prediction model for all-cause mortality in maintenance dialysis patients: a multicenter retrospective cohort study by Jingcan Wu, Xuehong Li, Hong Zhang, Lin Lin, Man Li, Gangyi Chen, Cheng Wang

“…Variables were selected by LASSO-Cox regression, and the model was constructed by Cox regression, which was presented in the form of nomogram and web-based tool. The discrimination and accuracy of the prediction model were assessed using C-indexes and calibration curves, while the clinical value was assessed by decision curve analysis (DCA).Results The best predictors of 1-, 3-, and 5-year all-cause mortality contained nine independent factors, including age, body mass index (BMI), diabetes mellitus (DM), cardiovascular disease (CVD), cancer, urine volume, hemoglobin (HGB), albumin (ALB), and pleural effusion (PE). …”
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Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro by Jianeng Li, Changle Zhao, Lei Liu, Shuqing Zheng, Deshou Wang, Changwei Shao, Jing Wei

“…This study provides a foundation for generating genome-edited sperm for germ-line transmission in this species and offers a valuable tool for investigating fish spermatogenesis in vitro.…”
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Structural Response Prediction of Floating Offshore Wind Turbines Based on Force-to-Motion Transfer Functions and State-Space Models by Jie Xu, Changjie Li, Wei Jiang, Fei Lin, Shi Liu, Hongchao Lu, Hongbo Wang

“…It represents a promising tool for enhancing the development and evaluation of offshore wind energy systems.…”
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Empowering recovery: a remote spirometry system and mobile app for monitoring and promoting pulmonary rehabilitation in patients with rib fracture by Ling-wei Kuo, Chih-Yuan Fu, Chien-An Liao, Chien-Hung Liao, Chi-Tung Cheng, Tai-Horng Young, Shih-Ching Kang, Szu-An Chen, Yu-San Tee

“…However, the device improves pulmonary function more in patients in a younger age group. This tool may be effective as a real-time, continuous pulmonary function monitoring system for patients with multiple rib fractures.Level of evidence Level IV.…”
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Moving from monitoring to real-time interventions for air quality: are low-cost sensor networks ready to support urban digital twins? by Nicole Hannah Cowell, Nicole Hannah Cowell, Lee Chapman, David Topping, Philip James, Daniel Bell, Thomas Bannan, Ettore Murabito, James Evans, Mark Birkin

“…Urban digital twins are the next logical step on this journey and these are becoming increasingly popular as a tool, at least conceptually, to better interpret this data as well as better understand the consequences of management interventions. …”
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Associations between serum total bilirubin and overactive bladder from the National Health and Nutrition Examination Survey by Bo Jiang, Bo Jiang, Bo Jiang, Cunbao Ling, Binbin Dong, Binbin Dong, Xiaoming Lu, Xiaoming Lu, Yadong Liu, Yadong Liu, Yadong Liu

“…Bilirubin could potentially serve as an intervention or risk assessment tool for OAB in future studies.…”
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Development and validation of an integrated model for the diagnosis of liver cirrhosis with portal vein thrombosis combined with endoscopic characters and blood biochemistry data:... by Jie Yang, Xu Zhang, Jia Chen, Xianghong Hou, Minghong Shi, Longlong Yin, Longchun Hua, Cheng Wang, Xiaolong Han, Shuyan Zhao, Guolan Kang, Ping Mai, Rui Jiang, Hongwei Tian

“…The validation got an AUC of 0.890 (95% CI, 0.831–0.934), A nomogram tool was finally established for application.Conclusion Blood test combined endoscopic characters could preliminarily predict the liver cirrhosis with portal vein thrombosis for cirrhotic patients undergoing endoscopic examination.…”
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Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study by Gaoyang Li, Shrikant S. Kolan, Franco Grimolizzi, Joseph Sexton, Giulia Malachin, Guro Goll, Tore K. Kvien, Tore K. Kvien, Nina Paulshus Sundlisæter, Manuela Zucknick, Siri Lillegraven, Espen A. Haavardsholm, Espen A. Haavardsholm, Bjørn Steen Skålhegg

“…A simplified model using RAID score alone demonstrated comparable performance to the full-feature model.ConclusionThese findings highlight the potential utility of baseline RAID score-based model as an effective tool for early identification of patients at risk of non-remission in clinical practise.…”
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Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis by Xiaotong Yu, Xiaotong Yu, Chen Huang, Chen Huang, Yan Song, Yan Song, Chun Zhang, Chun Zhang, Debo You, Debo You, XuRan Dong, XuRan Dong, DeFu Wu, DeFu Wu, Alan Keith Meeker, Hao Feng, Yuqing Wang, Yuqing Wang

“…As TSA-based mIHC/IF and its associated imaging systems and analytic software progress, it will become the most promising tool for describing the variety of the whole tissue for a better understanding of pathological or physiological behavior.…”
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Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT by Hao-Nan Zhu, Yi-Fan Guo, YingMin Lin, Zhi-Chao Sun, Xi Zhu, YuanZhe Li

“…Conclusion: CT-based radiomics can capture subtle changes in the thoracic vertebral bone marrow before breast cancer bone metastasis, offering a predictive tool for early detection of bone metastasis in breast cancer.…”
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Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness by Patricia Nabisubi, Stephen Kanyerezi, Grace Kebirungi, Ivan Sserwadda, Mike Nsubuga, Grace Kisitu, Patricia Ntege Nahirya, Bonny Mulindwa, George P. Akabwai, Sylvia Nantongo, Adeodata Kekitiinwa, Edgar Kigozi, Nsubuga Moses Luutu, Fred Ashaba Katabazi, Leymon Kalema, Andrew Katabalwa, Daudi Jjingo, Gerald Mboowa

“…While traditional diagnostic approaches focus on specific pathogens, shotgun metagenomic sequencing offers a comprehensive tool to explore the microbial landscape underlying NMFI in this vulnerable population ensuring effective management. …”
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Clinical features and outcomes of pseudolithiasis induced by ceftriaxone in Chinese children: a single-center observational study by Chen Jin, Chen Jin, Wen-Li Xiu, Wen-Li Xiu, Yao Liu, Yao Liu, Xi-Wei Hao, Qian Dong, Qian Dong

“…Overall, the findings demonstrate that ultrasound is an effective tool for monitoring the development of PL in children receiving CTX and that discontinuation of CTX could be an effective treatment for PL.…”
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Intraoperative Hyperspectral Imaging Predicts Early Allograft Dysfunction and Overall Survival in Liver Transplantation by Andri Lederer, MD, Antonia Alina Geisler, MD, Robert Sucher, MD, Daniel Seehofer, MD, Hans-Michael Hau, MD, Uwe Scheuermann, PD, Sebastian Rademacher, MD

“…HSI is a promising, noninvasive tool, offering real-time, detailed graft perfusion assessment during LT. …”
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