Gene Expression Signatures of Peripheral Blood Mononuclear Cells during the Early Post-Transplant Period in Patients Developing Cardiac Allograft Vasculopathy by Khurram Shahzad, Martin Cadeiras, Sarfaraz Memon, Barry Zeeberg, Tod Klingler, Anshu Sinha, Esteban G. Tabak, Sreevalsa Unniachan, Mario C. Deng

“…Our pilot data suggest that GEP of PBMC may become a valuable tool in the evaluation of patients at risk of CAV. …”
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The influence of weather and urban environment characteristics on upper respiratory tract infections: a systematic review by Henna Hyrkäs-Palmu, Henna Hyrkäs-Palmu, Timo T. Hugg, Timo T. Hugg, Jouni J. K. Jaakkola, Jouni J. K. Jaakkola, Tiina M. Ikäheimo, Tiina M. Ikäheimo, Tiina M. Ikäheimo

“…The quality of the studies was assessed using the AXIS appraisal tool, and the results analyzed by narrative synthesis.ResultsTwenty-one eligible studies focusing on COVID-19 and influenza transmissions, were included in the review. …”
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The Presence of Two Distinct Lineages of the Foot-And-Mouth Disease Virus Type A in Russia in 2013–2014 Has Significant Implications for the Epidemiology of the Virus in the Region... by Victor V. Nikiforov, Sergey A. Noskov, Alexander V. Sprygin, Mohammad Abed Alhussen, Anastasia S. Krylova, Taisia V. Erofeeva, Svetlana N. Fomina, Svetlana R. Kremenchugskaya, Fedor I. Korennoy, Maxim V. Patrushev, Ilya A. Chvala, Tamara K. Mayorova, Stepan V. Toshchakov

“…Molecular surveillance of FMD epidemiology is a fundamental tool for advancing our understanding of virus biology, monitoring virus evolution, and guiding vaccine design. …”
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A novel high-resolution eco-functional vegetation mapping of coastal dunes by Michele Innangi, Mirko Di Febbraro, Marco Balsi, Ginevra Colonna, Michele Finizio, Federica Pontieri, Maria Laura Carranza

“…This approach offers a valuable tool for ecosystem monitoring, supporting conservation management amid rising environmental pressures.…”
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A new approach for hemodynamics of varicoceles: blood flow patterns based on contrast-enhanced ultrasound by Penglin Zou, Gaoxiang Fan, Zheng Li, Yuchen Tao, Chao Jia, Hongmei Liang, Ruhui Tian, Qiusheng Shi, Jianlin Hu, Rong Wu

“…Contrast-enhanced ultrasound (CEUS), a powerful tool for hemodynamic analysis, remains unexplored for VC. …”
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Predicting CMEs Using ELEvoHI With STEREO‐HI Beacon Data by Maike Bauer, Tanja Amerstorfer, Jürgen Hinterreiter, Andreas J. Weiss, Jackie A. Davies, Christian Möstl, Ute V. Amerstorfer, Martin A. Reiss, Richard A. Harrison

“…Additionally, we introduce a Python tool for downloading and preparing STEREO‐HI data, as well as tracking CMEs. …”
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Papillary Urothelial Neoplasia with Low Malignant Potential (PUNLMP) in a 9-year-old Child: A Case Report and Review of Literature by Abbas Al Bazzal, Amarelle Chamoun, Zeinab Karaki, Ibrahim Ballout, Bachar Al Al, Linda Chamma, Hussein Issa, Mohamad Moussa, Hiba Hamdar

“…Ultrasound is the first line imaging tool for assessing bladder lesions, followed by cross-sectional imaging examinations such as computed tomography or magnetic resonance imaging if the diagnosis is uncertain. …”
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Navigating complex choices through legitimation: Narrative strategies in risk-reduction mastectomy decision-making among unaffected women with genetic risk for breast cancer in Swi... by Maria Caiata-Zufferey, Reka Schweighoffer, Monica Aceti, Carla Pedrazzani, Maria C. Katapodi, Souria Aissaoui, Mekdes Alemu, Murat Aykut, Fulvia Brugnoletti, Rachel Bunger, Nicole Bürki, Pierre O. Chappuis, Muriel Fluri, Rossella Graffeo, Karl Heinimann, Ashley Machen, Christian Monnerat, Olivia Pagani, Manuela Rabaglio, Eveline Schönau, Simon Wieser, Ursina Zürrer-Härdi

“…The discussion provides insights into the legitimation process as a heuristic tool for exploring crucial choices in uncertainty and offers implications for healthcare providers assisting individuals in complex decision-making processes.…”
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An Explainable Artificial Intelligence Model for the Classification of Breast Cancer by Tarek Khater, Abir Hussain, Riyad Bendardaf, Iman M. Talaat, Hissam Tawfik, Sam Ansari, Soliman Mahmoud

“…Therefore, artificial intelligence has revolutionized healthcare and can serve as a promising tool for early diagnosis. The present study aims to develop a machine-learning model to classify breast cancer and to provide explanations for the model results. …”
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Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review by Adriana Sánchez-García, René Rodríguez-Gutiérrez, Leonardo Mancillas-Adame, Victoria González-Nava, Alejandro Díaz González-Colmenero, Ricardo Cesar Solis, Neri Alejandro Álvarez-Villalobos, José Gerardo González-González

“…Diagnostic accuracy measures (sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratios) were extracted independently and in duplicate. The QUADAS-2 tool was used to assess the risk of bias of independent studies. …”
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Optimization of UAE-NADES green extraction of bioactive compounds from chickpea (Cicer arietinum L.) sprouts using simplex lattice mixture design methodology by Waseem Khalid, Hyrije Koraqi, Imed E Benmebarek, Andrés Moreno, Tawfiq Alsulami, Robert Mugabi, Gulzar Ahmad Nayik

“…In the present study, a statistical tool called the simplex lattice mixture design method was used to create a new formulation of Natural Deep Eutectic Solvent (NADES), which is derived from a combination of three compounds (citric acid, glycerol, and water) to extract bioactive compounds from chickpea (Cicer arietinum L.) sprouts. …”
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Efficacy and Safety of a Combination of Enteral and Parenteral Nutrition Support in the Postoperative Period for Patients with Gastrointestinal Cancer: A Systematic Review and Meta... by Meixiang Cai, Bo Yang, Yaping Zheng, Lei Ding

“…The Cochrane Risk of Bias Assessment tool was used to assess the quality of the RCTs. …”
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Efficiency enhancement in main path extraction in mRNA vaccine field: A novel approach leveraging intermediate patents, with shielding origin and terminus patent edges by Ting Zhang, Zhongquan Jian, Juan Chen, Dongzi Xu, Xiaoyi Yang, Yan Lu, Shu Yan, Lizi Pan, Qingqiang Wu, Zhaolian Ouyang

“…Main path analysis (MPA) is particularly effective for mapping out development trajectories within complex and interconnected networks, which serves as a powerful tool for identifying key nodes and innovations. This study introduces a novel approach to extracting main paths from a patent citation network in the mRNA vaccine field. …”
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STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation by Yu Qian Wong, Hongyan Xu, Qiang Wu, Xinyu Liu, Chengchen Lufei, Xiu Qin Xu, Xin-Yuan Fu

“…Taken together, the findings of this study indicated that InSTAT3 KO and InSTAT3 CA ESCs could provide a new tool to clarify the direct targets of STAT3 and its role in ESC maintenance, which will facilitate the elaboration of the mechanisms whereby STAT3 maintains ESC pluripotency and regulates ESC differentiation during mammalian embryogenesis.…”
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Investigation of corrosion and water absorption of biomass natural coir fiber/hBN reinforced epoxy hybrid composites using different optimisation approaches by Ramraji Kirubakaran, Shenbaga Velu Pitchumani, Sanju Tom, R. Ashwin Nagaraj, P. Salin, Harish Kumar Natchimuthu, Venkatachalam Gopalan, G. Vinayagamurthy

“…The study uses a Box-Behnken Design (BBD-L15), a statistical experimental design tool that facilitates the effective investigation of many input parameters and their interactions, to comprehensively investigate these impacts. …”
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Estimation Model of Global Ionospheric Irregularities: An Artificial Intelligence Approach by Penghao Tian, Bingkun Yu, Hailun Ye, Xianghui Xue, Jianfei Wu, Tingdi Chen

“…Deep learning is a powerful tool for mining latent features from data, which can theoretically avoid assumptions constraining physical methods. …”
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Impact of the Relationship between Extensor Pollicis Brevis Entrapment Test and Ultrasound Wrist Findings and Functional Outcomes in De Quervain's Disease by Vijayaraja Elangovan, Lokesh K Sekaran, Harisudhan Raviraja, Dheepan Kumar, Ganesan G Ram

“…The extensor pollicis brevis (EPB) entrapment test has emerged as a valuable diagnostic tool. Integrating clinical assessment with ultrasound examination improves diagnostic efficacy, highlighting the importance of evaluating functional outcomes. …”
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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

“…Conclusions: Our results demonstrate that a reproducible NGS-based workflow translates into a reliable tool for the clinical stratification of patients with UM.…”
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SECTM1 acts as an immune-related biomarker of poor prognosis and promotes cancer progression by modulating M2 macrophage polarization in esophageal squamous cell carcinoma by Pengzhou Kong, Pengzhou Kong, Pengzhou Kong, Ye Jiao, Ye Jiao, Meng Sun, Meng Sun, Zhinan Zhou, Zhinan Zhou, Yingying Zhang, Yingying Zhang, Xin Yang, Xin Yang, Jing Ren, Jing Ren, Mengyuan Yang, Mengyuan Yang, Yanyan Dong, Yanyan Dong, Yanyan Dong, Bin Song

“…In a Conclusion, our study established a prognostic prediction model based on immune-related gene signature, which provided a reliable prognostic tool for ESCC and identified SECTM1 as a potential biomarker in ESCC.…”
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Explainable AutoML models for predicting the strength of high-performance concrete using Optuna, SHAP and ensemble learning by Muhammad Salman Khan, Tianbo Peng, Tianbo Peng, Muhammad Adeel Khan, Asad Khan, Mahmood Ahmad, Mahmood Ahmad, Kamran Aziz, Mohanad Muayad Sabri Sabri, N. S. Abd EL-Gawaad

“…This approach provides civil engineers with a robust and interpretable tool for optimizing HPC properties, reducing experimentation costs, and supporting enhanced decision-making in structural design, risk assessment, and other applications.…”
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