In Vivo Evaluation of the Combined Anticancer Effects of Cisplatin and SAHA in Nonsmall Cell Lung Carcinoma Using [18F]FAHA and [18F]FDG PET/CT Imaging by Skye Hsin-Hsien Yeh, Ming Hsien Lin, I. I. Leo Garcia Flores, Uday Mukhopadhyay, Danial Young, Kazuma Ogawa, Jeong-Hwan Jeong, William Tong, Juri G. Gelovani, Nobuyoshi Fukumitsu

“…In conclusion, [18F] FAHA enables quantitative visualization of HDAC activity/expression in vivo, thus, may represent a clinically useful, noninvasive tool for the management of patients who may benefit from synergistic anticancer therapy.…”
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Enhancing immunotherapy efficacy with synergistic low-dose radiation in metastatic melanoma: current insights and prospects by Zahid Rafiq, Mingyo Kang, Hampartsoum B. Barsoumian, Gohar S. Manzar, Yun Hu, Carola Leuschner, Ailing Huang, Fatemeh Masrorpour, Weiqin Lu, Nahum Puebla-Osorio, James W. Welsh

“…LDRT has emerged as a potent tool for stimulating the immune system, triggering systemic antitumor effects by remodeling the tumor microenvironment. …”
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Project “BUSSARD” − a holistic development of high-efficiency solar cells covering innovative front-end, metallization and interconnection approaches by Lorenz Andreas, Schube Jörg, Nikitina Veronika, Mack Sebastian, Schweigert Sebastian, Buddgard Jonas, Albrecht Jonas, Pospischil Maximilian, Kraft Achim, Wolf Andreas, Hermle Martin, Clement Florian

“…We demonstrate the feasibility on small-scale and full-format modules and analyze the I–V results as well as cell-to-module (CTM) loss analysis using the simulation tool SmartCalc®. The results are compared to TOPCon modules interconnected via SmartWire Connection Technology (SWCT) and electrically conductive adhesive (ECA).…”
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Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis by Gabriel Romero Liguori, Qihui Zhou, Tácia Tavares Aquinas Liguori, Guilherme Garcia Barros, Philipp Till Kühn, Luiz Felipe Pinho Moreira, Patrick van Rijn, Martin C. Harmsen

“…These data suggest that nanotopography may be a novel tool for inhibiting fibrosis.…”
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Delay between Onset of Symptoms and Seeking Physician Intervention Increases Risk of Diabetic Foot Complications: Results of a Cross-Sectional Population-Based Survey by Norina A. Gavan, Ioan A. Veresiu, Etta J. Vinik, Aaron I. Vinik, Bogdan Florea, Cosmina I. Bondor

“…We present a post hoc analysis of 17,530 questionnaires collected as part of the 2012 screening for neuropathy using Norfolk Quality of Life tool in patients with diabetes in Romania, to assess the impact on foot complications of time between the onset of symptoms of diabetes/its complications and the physician visit. …”
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Research progress on the application of bedside lung ultrasound in ICU nursing (床旁肺部超声在ICU护理中应用的研究进展) by TAN Huiting (谭慧婷), WANG Fengying (王凤英), LI Fangfang (李芳芳), GUO Yanyun (郭艳云), XUE Chao (薛超)

“…With the development of critical care medicine, bedside lung ultrasound, as an effective auxiliary diagnostic tool, has been widely used in intensive care unit nursing. …”
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Metabolomics Reveals Distinct Metabolites between Lonicera japonica and Lonicera macranthoides Based on GC-MS by Rui-ying Liu, Jing Deng, Xiu-Lian Lin, Ya-mei Li, Yan Lin, Bo-hou Xia, Li-mei Lin

“…Consequently, this study presented an effective tool for quality evaluation of LJ and LM and laid a foundation for further studies of the metabolic mechanisms and high-quality manufacturing of them.…”
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Harmonizing the past: EEG-based brain network unveil modality-specific mechanisms of nostalgia by Hu Shuxiang, Hu Shuxiang, Liu Ying, Liu Ying, Yue Qizong, Yue Qizong, Zhao Huan, Zhao Huan, Zheng Maoping, Zheng Maoping

“…Further research is needed to explore the potential of nostalgia as an adjunctive therapeutic tool.…”
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Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography by Pierre-Maxime Lévêque, Pierre Zéboulon, Emmanuelle Brasnu, Christophe Baudouin, Antoine Labbé

“…OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.…”
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Simultaneous production during biogas upgrading: Foundational insights from numerical simulation of dual-reflux pressure swing adsorption by Mohd Hardyianto Vai Bahrun, Awang Bono, Norasikin Othman, Muhammad Abbas Ahmad Zaini

“…In this study, a numerical simulation model of a non-isothermal DR-PSA was established using the Aspen Adsorption simulation tool to evaluate the dynamics of the system for binary separation of biogas feed mixture containing 45 mol% CO2 + 55 mol% CH4, using a CO2-selective silica gel as the solid adsorbent. …”
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Revisiting the Metabolism of Donepezil in Rats Using Non-Targeted Metabolomics and Molecular Networking by Eun-Ji Park, Eui-Hyeon Kim, Ki-Young Kim, Ji-Hyeon Jeon, Im-Sook Song, So-Young Park, Kwang-Hyeon Liu

“…This study indicates that a MN approach combined with a metabolomics approach is a reliable tool to identify unknown metabolites of drugs and drug candidates.…”
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Multiplex one-step RT‒qPCR assays for simultaneous detection of AMDV, MEV and CDV by Zhi Cao, Hang Xu, Xinru Zhao, Ke Zhang, Dehua Yin, Shuai Ma, Wenling Li, Siyu Li, Jianwei Ren, Jianxin Wen

“…Conclusions In conclusion, multiplex RT‒qPCR exhibited high specificity, sensitivity, and reproducibility, indicating that this method can be used as a reliable and specific tool for the differential detection and quantification of AMDV, MEV and CDV.…”
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B-phosphatidylethanol testing to identify hazardous alcohol use in primary health care—a game changer and a challenge for general practitioners: a qualitative study by Åsa Steensland, Anna Segernäs, Mårten Larsson, Andrea Johansson Capusan, Lisa Kastbom

“…Four categories underpinned this theme: Comprehending the context, describing the challenges in the GP-patient interaction when hazardous alcohol use or AUD was suspected; Getting the pieces in place, illustrating the struggle of integrating PEth testing into clinical practice and how it diminished the role of alcohol history taking; The challenges and facilitators of the conversation, comprising both the difficulties in informing about PEth testing and the positive impact on the interaction, and Considerations based on the PEth test results, emphasising the consequences of elevated PEth test results and their influence on physicians’ motivation to using PEth.Conclusions PEth is an important tool in the identification of hazardous alcohol use. …”
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Development of an Augmented Reality-Based Practicum E-Module Integrated with Local Wisdom of Salak Fruit by Heni Mulyani Pohan, Adi Syaputra, Fatma Suryani Harahap, Dinda Yunita, Rabiyatul Adawiyah Siregar, Anouar Ben Mabrouk

“…The integration of augmented reality (AR) technology into education has gained attention as an innovative tool to enhance students' learning experiences, particularly for abstract concepts such as chemical bonding. …”
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Sensitivity, Specificity, Predictive Values, and Accuracy of Three Diagnostic Tests to Predict Inferior Alveolar Nerve Blockade Failure in Symptomatic Irreversible Pulpitis by Daniel Chavarría-Bolaños, Laura Rodríguez-Wong, Danny Noguera-González, Vicente Esparza-Villalpando, Mauricio Montero-Aguilar, Amaury Pozos-Guillén

“…None of the analyzed tests demonstrated a high enough accuracy to be considered a reliable diagnostic tool for the prediction of anesthetic failure.…”
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Evaluation of parent and youth experiences in advisory groups as part of a mental healthcare clinical trial: protocol for a mixed-method study by Maria-Jose Santana, Gina Dimitropoulos, Suneeta Monga, Isabelle J Gagnon, Bruce Wright, Jananee Rasiah, Katrina Hurley, Antonia Stang, Amanda Newton, Stephen Freedman, Jennifer Thull-Freedman, Kassi Prisnie, Yazid N Al Hamarneh, Ellen Louise Lipman, Yaron Finkelstein, Robert Porter, Mohamed Eltorki, Lee Macdonald, Gareth Hopkin, Matthew Prebeg, Margaret Steele, Ahmed Mater, Laurence Katz, Brian Greenfield, Laurie Plotnick

“…Engagement will be evaluated using the participant and project questionnaires of the Public and Patient Engagement Evaluation Tool (PPEET), followed sequentially by semi-structured interviews. …”
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Health State Utility Values in Children and Adolescents with Disabilities: A Systematic Review by Lucy Kanya, PhD, Nana Anokye, PhD, Ahmad Hecham Alani, PharmD, Nandini Jayakumar, MSc, Jennifer M. Ryan, PhD

“…Studies quality was assessed using a novel tool derived from 3 validated checklists. Results: Of the 3541 screened articles, 31 met inclusion criteria. …”
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TraxVBF: A hybrid transformer-xLSTM framework for EMG signal processing and assistive technology development in rehabilitation by Seyyed Ali Zendehbad, Athena Sharifi Razavi, Marzieh Allami Sanjani, Zahra Sedaghat, Saleh Lashkari

“…These results indicate that TraxVBF may be a useful tool to improve motor learning and rehabilitation, and longer term clinical trials and multi-sensory biofeedback are needed.…”
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Patient preferences for drug therapy in inflammatory arthritis: protocol for a living systematic review and evidence map to inform clinical practice guidelines by Rachelle Buchbinder, Peter Tugwell, Pablo Alonso-Coello, Mickael Hiligsmann, Nick Bansback, Laurie Proulx, Dawn P Richards, Wojtek Wiercioch, Glen Hazlewood, Samuel Whittle, Jordi Pardo Pardo, Marie Falahee, Holger Schünemann, Robby Nieuwlaat, Pakeezah Saadat, Simon Kuper

“…Risk of bias will be assessed using the GRADE risk of bias tool. An evidence map will be generated to summarise included studies and their assessments of each trade-off. …”
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Combining interictal intracranial EEG and fMRI to compute a dynamic resting-state index for surgical outcome validation by Varina L. Boerwinkle, Kristin M. Gunnarsdottir, Bethany L. Sussman, Sarah N. Wyckoff, Emilio G. Cediel, Belfin Robinson, William R. Reuther, Aryan Kodali, Sridevi V. Sarma

“…We developed a novel seizure onset network characterization tool that combines dynamic biomarkers of resting-state intracranial stereoelectroencephalography (rs-iEEG) and resting-state functional magnetic resonance imaging (rs-fMRI), vetted against surgical outcomes. …”
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