Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy by Fermín E. González, Alexey Chernobrovkin, Cristián Pereda, Tamara García-Salum, Andrés Tittarelli, Mercedes N. López, Flavio Salazar-Onfray, Roman A. Zubarev

“…Autologous dendritic cells (DCs) loaded with cancer cell-derived lysates have become a promising tool in cancer immunotherapy. During the last decade, we demonstrated that vaccination of advanced melanoma patients with autologous tumor antigen presenting cells (TAPCells) loaded with an allogeneic heat shock- (HS-) conditioned melanoma cell-derived lysate (called TRIMEL) is able to induce an antitumor immune response associated with a prolonged patient survival. …”
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Improving Road Semantic Segmentation Using Generative Adversarial Network by Arnick Abdollahi, Biswajeet Pradhan, Gaurav Sharma, Khairul Nizam Abdul Maulud, Abdullah Alamri

“…Road network extraction from remotely sensed imagery has become a powerful tool for updating geospatial databases, owing to the success of convolutional neural network (CNN) based deep learning semantic segmentation techniques combined with the high-resolution imagery that modern remote sensing provides. …”
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Rating pome fruit quality traits using deep learning and image processing by Nhan H. Nguyen, Joseph Michaud, Rene Mogollon, Huiting Zhang, Heidi Hargarten, Rachel Leisso, Carolina A. Torres, Loren Honaas, Stephen Ficklin

“…Moreover, while these visual assessments are critical empirical data, they are often coarse‐grained and lack consistent objective criteria. Granny, is a tool designed for rating fruit using machine‐learning and image‐processing to address rater bias and improve resolution. …”
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LEA Gene Expression Assessment in Advanced Mutant Rice Genotypes under Drought Stress by Zarifth Shafika Kamarudin, Mohd Rafii Yusop, Mohd Razi Ismail, Mahmud Tengku Muda Mohamed, Abdul Rahim Harun, Oladosu Yusuff, Usman Magaji, Arolu Fatai

“…Hence, LEA genes could be served as a potential tool for drought tolerance determination in rice. …”
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Epilepsy Diagnosis from EEG Signals Using Continuous Wavelet Transform-Based Depthwise Convolutional Neural Network Model by Fırat Dişli, Mehmet Gedikpınar, Hüseyin Fırat, Abdulkadir Şengür, Hanifi Güldemir, Deepika Koundal

“…The developed model and image concatenation method offer a novel methodology for epilepsy diagnosis that can be extended to different datasets, potentially providing a valuable tool to support neurologists globally.…”
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Problem-based learning in developing students’ communicative skills and creativity in teaching English for specific purposes by Jolita Šliogerienė, Irena Darginavičienė, Jelena Suchanova, Dalia Gulbinskienė, Viktorija Jakučionytė

“…Despite some negative attitudes on the part of some students, problem-based learning remains a valuable tool in English for specific purposes education, supporting the development of language and professional skills. …”
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Diagnostic efficiency of exome-based sequencing in pediatric patients with epilepsy by Huafang Zou, Huafang Zou, Qian Zhang, Jianxiang Liao, Jianxiang Liao, Dongfang Zou, Zhanqi Hu, Bing Li, Li Chen, Jialun Wen, Xia Zhao, Victor Wei Zhang, Dezhi Cao, Dezhi Cao

“…Next-generation sequencing (NGS) has emerged as a robust diagnostic tool for this condition. This study aims to evaluate the detection efficiencies of different exome-based sequencing techniques.MethodsExome-based epilepsy panel tests, clinical exome sequencing (CES), and whole exome sequencing (WES) were conducted on 259 pediatric patients diagnosed with epilepsy. …”
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Integrated Care for People Living With Rare Disease: A Scoping Review on Primary Care Models in Organization for Economic Cooperation and Development Countries by Nada Vidic, Anna McGlynn, Fatemeh Abdi, Chun Wah Michael Tam, Reginald Michael Crampton, Kean-Seng Lim, Elizabeth Emma Palmer, Natalie Taylor, Ben Harris-Roxas

“…Methods: This scoping review used Joanna Briggs Institute and PRISMA methods with a Consolidated Framework for Implementation Research based data extraction tool to find how integrated rare-disease-care is delivered, enablers and barriers to the same, in primary care settings in contemporary literature in OECD countries. …”
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Exploring the Transformative Potential of Learning Analytics in Medical Education: A Systematic Review by EHSAN TOOFANINEJAD, SHANE DAWSON, SOMAYE SOHRABI, MASOMEH KALANTARION

“…Introduction: Learning Analytics (LA) has emerged as a potent tool in medical education, offering data-driven insights and personalized support to learners. …”
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Large-Scale Screening in General Population Children for Celiac Disease with a Multiplex Electrochemiluminescence (ECL) Assay by Ling He, Xiaofan Jia, Yong Gu, Dongmei Miao, Kathleen Waugh, Cristy Geno, Edwin Liu, Marian Rewers, Liping Yu

“…It also provides a high efficient tool with its unique advantage of multiplexing measurements to screen for multiple autoimmune diseases simultaneously in general population.…”
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A concise practical clinical guide to identifying spasticity in neurological shoulder dysfunction by Damon Hoad, Stephen Ashford, Stephen Ashford, Ganesh Bavikatte, Rachel Farrell, Rachel Farrell, Adrian Robertson, Jörg Wissel, Jörg Wissel

“…During an in-person meeting in March 2023, a consensus-building process was used to discuss four topics: a checklist/tool to identify shoulder involvement in upper limb spasticity, measurements/scales for assessing shoulder spasticity, ‘red flags’ for other conditions affecting the shoulder, and assessment limitations and practicalities.ResultsWhere there was full agreement on a topic, recommendations to overcome challenges for initial and ongoing assessment of shoulder spasticity and goal-setting were developed, and categorized as Posture, Purposeful activity and Pain (‘the three Ps’). …”
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Lipid Biomarkers in Urban Soils of the Alluvial Area near Sava River, Belgrade, Serbia by Gordana Dević, Sandra Bulatović, Jelena Avdalović, Nenad Marić, Jelena Milić, Mila Ilić, Tatjana Šolević Knudsen

“…The methodology developed in this study was proven to be efficient for the assessment of the environmental quality of the soil in an urban part of New Belgrade, but it can also be a useful tool for soil monitoring and for a pollution assessment in other (sub)urban areas.…”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Neural crest-derived mesenchymal stem cells (MSCs) from human oral tissues possess immunomodulatory and regenerative properties and are emerging as a potential therapeutic tool to treat diverse diseases, such as multiple sclerosis, myocardial infarction, and connective tissue damages. …”
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Comparative Analysis of Freeze-Dried <i>Pleurotus ostreatus</i> Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds by Gréta Törős, Áron Béni, Ferenc Peles, Gabriella Gulyás, József Prokisch

“…<i>Pleurotus ostreatus</i> (oyster mushroom) holds excellent promise worldwide, bringing several opportunities and augmenting the tool sets used in the biotechnology field, the food industry, and medicine. …”
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Application of a new composite genetic marker semen-specific methylation-microhaplotype in the analysis of semen–vaginal fluid mixtures by Dan Wen, Hao Xing, Xuan Tang, Yue Wang, Bowei Jiang, Jienan Li, Ying Liu, Lagabaiyila Zha

“…This preliminary study suggests that this new composite genetic marker has great potential as a supplementary tool to commonly used genetic markers (STR, etc.) for analysing semen–vaginal fluid mixtures.…”
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Evaluation of the quality of standing trees using an Arbotom acoustic stress tomograph by Michajlová Katarína, Gejdoš Miloš, Gergeľ Tomáš, Gretsch Dominik

“…Acoustic equipment utilizing excited stress acoustic waves has emerged as a valuable tool for evaluating the internal structure of standing trees. …”
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How to build a framework to establish a patient research partner network in rheumatology research: a report of a 2-year implementation project by Maarten de Wit, Oliver Distler, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Muriel Elhai, Rucsandra Dobrota, Adrian Ciurea, Caroline Ospelt, Raphael Micheroli, Dania Diem, Stefan Dudli, Kristina Buerki, Stacey Grealis, Melpomeni Toitou, Silke Ludwig, Chantal Britt, Florian Klett, Isabelle Steeb, Tanja Maletic, Andreas Eisenring, Penelope Jane Timpert-Argust, Eva Camarillo-Retamosa

“…The initiative was qualitatively assessed via an online questionnaire developed by each six researchers and PRPs.Results Communicating our initiative at laboratory open days and to patient associations has enabled to create a network of 66 PRPs. A match-making tool was introduced to allocate interested PRPs with a project request. …”
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Evaluation of the diagnostic efficiency of fluorescence in situ hybridization for pulmonary tuberculosis: a systematic review and meta-analysis by Yu-Qi Hu, Yu-Qi Hu, Kang Liu, Kang Liu, Le-Qing Lai, Le-Qing Lai, Yi-Ru He, Yi-Ru He, Li-Ping Hong, Li-Ping Hong, Chu-Qian Jiang, Chu-Qian Jiang, Si-Min Liu, Si-Min Liu, Ming-Zhu Cao

“…We hope this study will find a new and effective tool for the early diagnosis of PTB.…”
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Is acupuncture effective for knee osteoarthritis? A protocol for a systematic review and meta-analysis by Jing-Wen Yang, Jian-Feng Tu, Myeong Soo Lee, Chuan-Yang Liu, Ling-Yu Qi, Fang-Ting Yu, Shi-Yan Yan, Jin-Ling Li, Lu-Lu Lin, Xiao-Wan Hao, Xin-Tong Su, Li-Qiong Wang

“…Risk of bias will be assessed using the Cochrane Collaboration’s tool for assessing risk of bias. Article selection, data extraction and risk of bias assessment will be performed in duplicate by two independent reviewers. …”
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Prediction of mortality risk in patients with severe community-acquired pneumonia in the intensive care unit using machine learning by Jingjing Pan, Tao Guo, Haobo Kong, Wei Bu, Min Shao, Zhi Geng

“…The web calculator based on the LightGBM model can provide clinicians with a prognostic evaluation tool.…”
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