The value of metagenomic next-generation sequencing in the diagnosis of fever of unknown origin by Lan Min Lai, Qing-gen Chen, Yang Liu, Rui Zhao, Mei Ling Cao, Lei Yuan

“…Metagenomic next-generation sequencing (mNGS) technology is a promising diagnostic tool for identifying pathogenic microbes of FUO caused by infection. …”
Get full text

Improving Visual Field Awareness among Collegiate Softball Athletes: A Randomized Trial by Diana R. Feldhacker, Whitney Lucas Molitor

“…Therefore, both Dynavision^TM D2 training and alternative vision training may be effective training methods to improve the visual field awareness and reaction time of an elite athletic population; however, the Dynavision^TM D2 may be a more effective tool. There was a statistically significant difference between Group A and Group B, with Group A experiencing more significant improvements than Group B in number of hits in quadrants 2 and 4 and rings 2 and 3 as well as speeds within quadrants 1 and 2 and ring 2 and 5. …”
Get full text

A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…This novel mouse model represents a powerful and practical tool to investigate the pathogenesis of T. brucei-mediated heart damage and supports the development of therapeutic options for T. brucei-associated cardiac disease. …”
Get full text

Therapeutic potential of adipose-derived stem cells for diabetic foot ulcers: a systematic review and meta-analysis by Mohamed A. Abu Elainein, Mohamad Mahmoud Whdan, Mahmoud Samir, Nada G. Hamam, Mohamed Mansour, Mohamed Abdel Mohsen Mohamed, Mahmoud Mostafa Snosy, Mahmoud Ayman Othman, Ahmed Sayed Sobieh, Mahmoud Gamal Saad, Mohamed A. Labna, Salma Allam

“…The Cochrane risk of bias (RoB 2) assessment tool was used to identify the risk of bias in our included studies. …”
Get full text

Deep learning-based algorithm for classifying high-resolution computed tomography features in coal workers’ pneumoconiosis by Hantian Dong, Biaokai Zhu, Xiaomei Kong, Xuesen Su, Ting Liu, Xinri Zhang

“…The classification of clinical imaging features from high-resolution computed tomography might become a powerful clinical tool for diagnosing pneumoconiosis in the future. …”
Get full text

A Nomogram Based on Laboratory Data, Inflammatory Bowel Disease Questionnaire and CT Enterography for Activity Evaluation in Crohn’s Disease by Zhang H, Shen Y, Cao B, Zheng X, Zhao D, Hu J, Wu X

“…Significant differences in AUC were observed between the two models (radiomic signature vs clinical, P = 0.026; radiomic signature vs IBDQ + clinical, P = 0.011; radiomic signature vs combined, P = 0.008; in the validation set).Conclusion: The nomogram, combined with laboratory data, IBDQ and rad-score, presents an accurate and reliable method for assessing CD activity.Clinical Impact: The nomogram enhances the potential for personalized treatment plans and better disease management, making it a valuable tool for clinical practice.Keywords: Crohn’s disease, laboratory data, quality of life, nomogram, CT enterography…”
Get full text

Interpreting machine learning models based on SHAP values in predicting suspended sediment concentration by Houda Lamane, Latifa Mouhir, Rachid Moussadek, Bouamar Baghdad, Ozgur Kisi, Ali El Bilali

“…Machine learning (ML) has become a powerful tool for predicting suspended sediment concentration (SSC). …”
Get full text

The associations between sedentary behavior and neck pain: a systematic review and meta-analysis by Yunchen Meng, Yaqi Xue, Sanjun Yang, Fang Wu, Yanyu Dong

“…The National Institute of Health (NIH) quality assessment tool was utilized to evaluate study quality. Odds ratios (ORs) and relative risks (RRs) with 95% confidence intervals (CIs) were used to assess the association between SB and NP. …”
Get full text

Reinforcement Learning-Based Generative Security Framework for Host Intrusion Detection by Yongsik Kim, Su-Youn Hong, Sungjin Park, Huy Kang Kim

“…A Host-based Intrusion Detection System (HIDS) is a highly effective tool for monitoring computer systems and detecting unusual or unauthorized activities. …”
Get full text

Prevalence of peripheral artery disease in young coronary artery disease patients by Medikonda Malla Reddy, N. Krishna Geetha, Kakumani Jagadeswar, I. Mariraj, K.I.S.N. Vaishnavi, Fahad Dadu, Gowri Shankar A.

“…ABI is a valuable diagnostic tool in young populations for detecting early signs of CHD, offering advantages over routine blood pressure measurements. …”
Get full text

Identifying community-driven priority questions in acoustic backscatter research by Vincent Lecours, Benjamin Misiuk, Benjamin Misiuk, Felix Butschek, Felix Butschek, Philippe Blondel, Giacomo Montereale-Gavazzi, Vanessa L. Lucieer, Chris McGonigle

“…IntroductionRemotely-sensed acoustic backscatter is an indispensable tool for seabed mapping, among other disciplines. …”
Get full text

Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…Conclusions The segmentation model serves as a valuable tool for the automated delineation of adnexal lesions. …”
Get full text

Evaluating the Effectiveness of InsightApp for Anxiety, Valued Action, and Psychological Resilience: Longitudinal Randomized Controlled Trial by Victoria Amo, Falk Lieder

“…InsightApp is a gamified EMI and research tool that incorporates elements from evidence-based therapeutic approaches. …”
Get full text

Increasing Access to Mental Health Supports for 18- to 25-Year-Old Indigenous Youth With the JoyPop Mobile Mental Health App: Study Protocol for a Randomized Controlled Trial by Angela MacIsaac, Teagan Neufeld, Ishaq Malik, Elaine Toombs, Janine V Olthuis, Fred Schmidt, Crystal Dunning, Kristine Stasiuk, Tina Bobinski, Arto Ohinmaa, Sherry H Stewart, Amanda S Newton, Aislin R Mushquash

“…Positive findings may support the integration of the app into mental health services as a waitlist management tool. Trial RegistrationClinicalTrials.gov NCT05991154; https://clinicaltrials.gov/study/NCT05991154 International Registered Report Identifier (IRRID)DERR1-10.2196/64745…”
Get full text

Health Services Availability and Readiness for Management of Hypertension and Diabetes in Primary Care Health Facilities in Ghana: a Cardiovascular Risk Management project by Thomas Hinneh, Bernard Mensah, Hosea Boakye, Oluwabunmi Ogungbe, Yvonne Commodore-Mensah

“…Methods: We adapted the World Health Organization (WHO) Service Availability and Readiness Assessment (SARA) tool to assess hypertension and diabetes management practices between June and July 2022 in four district hospitals in Ghana. …”
Get full text

Pharmacognostic analysis and antimalarial evaluation of quercetin in Ilex umbellulata bark using HPTLC, in vitro screening, molecular docking, and network pharmacology by James H. Zothantluanga, Dipak Chetia, Yasangam Umbon, T. C. Lalhriatpuii, Dhritiman Roy, Nidahun Lamare, Salem Lalvenhimi

“…With a mobile phase of toluene: ethyl acetate: formic acid (5:4:0.2 v/v), the validated TLC densitometric studies revealed the presence of 2.07 mg of quercetin (R f = 0.477 ± 0.005) in 100 mg of 80% MeOH bark extract of I. umbellulata. JazQSAR web tool previously developed by us predicts the IC50 of quercetin against Plasmodium falciparum as 3.88 ± 0.35 µM, which was not far from the practically observed value for quercetin. …”
Get full text

A Risk Management Approach to Global Pandemics of Infectious Disease and Anti-Microbial Resistance by Annie Sparrow, Meghan Smith-Torino, Samuel M. Shamamba, Bisimwa Chirakarhula, Maranatha A. Lwaboshi, Christine Stabell Benn, Konstantin Chumakov

“…Chlorine, our primary tool of public health, conquered cholera and transformed infection control in hospitals. …”
Get full text

Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…It has been successfully applied to the pharmacokinetic studies of PPIs and P-CABs, offering a valuable tool for clinical research and therapeutic drug monitoring.Keywords: acid-suppressing drugs, PPIs, P-CAB, UPLC-MS/MS…”
Get full text

Predictive value of the perivascular fat attenuation index for MACE in young people suspected of CAD by Yani Yu, Dongkai Shan, Xi Wang, Zinuan Liu, Guanhua Dou, Junjie Yang, Yuqi Liu, Yundai Chen

“…Conclusion The high perivascular FAI at the proximal segment of the RCA is significantly associated with an increased risk of long-term MACE and may be a potential tool for cardiovascular risk stratification in young people suspected of CAD.…”
Get full text

Optimization of SiC reinforced Al7039/Cu composites for enhanced thermal conductivity and hardness via response surface methodology by Fetene Teshome Teferi, Kishor Purushottam Kolhe, Assefa Asmare Tsegaw, Samuel Olawale Fatoba

“…The optimized Al7039/Cu/SiC composites exhibit significant enhancements over the base alloy, offering excellent properties suitable for demanding applications such as heat sinks, heat exchangers, mold tooling, and critical components in the automotive and aerospace sectors. …”
Get full text