The INFLUENCE 3.0 model: Updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy by M.C. Van Maaren, T.A. Hueting, D.J.P. van Uden, M. van Hezewijk, L. de Munck, M.A.M. Mureau, P.A. Seegers, Q.J.M. Voorham, M.K. Schmidt, G.S. Sonke, C.G.M. Groothuis-Oudshoorn, S. Siesling

“…Methods: Women, surgically treated for nonmetastatic breast cancer, diagnosed between 2012 and 2016, were selected from the Netherlands Cancer Registry. Cox regression with restricted cubic splines was compared to Random Survival Forest (RSF) to predict five-year LRR and CBC risks. …”
Get full text

Prospective Analysis of Confocal Laser Endomicroscopy for Assessment of the Resection Bed for Bladder Tumor by Ben-Max de Ruiter, Jan E. Freund, C. Dilara Savci-Heijink, Jons W. van Hattum, Marinka J. Remmelink, Theo M. de Reijke, Joyce Baard, Guido M. Kamphuis, D. Martijn de Bruin, Jorg R. Oddens

Get full text

Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality by Noor A. M. Bakker, Hannah Garner, Ewald van Dyk, Elisa Champanhet, Chris Klaver, Maxime Duijst, Leonie Voorwerk, Iris Nederlof, Rosie Voorthuis, Marte C. Liefaard, Marja Nieuwland, Iris de Rink, Onno B. Bleijerveld, Hendrika M. Oosterkamp, Lodewyk F. A. Wessels, Marleen Kok, Karin E. de Visser

Get full text

Development of a virtual surgical plan for reverse shoulder arthroplasty as a treatment for complex proximal humerus fracture in an elderly patient by Roelof J. van Luit, MD, Jessie Rijntjes, MSc, Edsko Hekman, MSc, Lonneke Govaert, MD, Freek Hollman, PhD, Femke F. Schröder, PhD, Egbert J.D. Veen, PhD

Get full text

Multi-omics analysis reveals distinct gene regulatory mechanisms between primary and organoid-derived human hepatocytes by Haoyu Wu, Annie S. P. Yang, Suzan Stelloo, Floris J. M. Roos, René H. M. te Morsche, Anne H. Verkerk, Maria V. Luna-Velez, Laura Wingens, Johannes H. W. de Wilt, Robert W. Sauerwein, Klaas W. Mulder, Simon J. van Heeringen, Monique M. A. Verstegen, Luc J. W. van der Laan, Hendrik Marks, Richárd Bártfai

Get full text

Young TPI: empowering animal-free science among the next- generation of scientists by Marta G. Valverde, Marta G. Valverde, Fatima Zohra Abarkan, Fatima Zohra Abarkan, Rebecca Van Eijden, Rebecca Van Eijden, Julia M. L. Menon, Julia M. L. Menon, Nikolas Gaio, Nikolas Gaio, Aarti Ramchandran, Aarti Ramchandran, Victoria C. De Leeuw, Victoria C. De Leeuw

“…Grounded on three pillars - collaboration, awareness-raising, and networking - Young TPI has evolved into a premier youth network in the Netherlands. Boasting over 270 members spanning Dutch 49 institutions, including biotechnology startups and pharmaceutical companies and universities, Young TPI harnesses the diverse expertise of its members to propel a sustainable, future-proof transition and to promote a continuous dialogue with a wide range of stakeholders. …”
Get full text

Development of the Dutch translational knowledge agenda for inherited metabolic diseases by I. J. Hieltjes, J. H. van derLee, M. C. Groenendijk, G. vanHaaften, P. M. vanHasselt, R. J. Lunsing, G. J. J. vanProoijen, E. M. deRuiter, F. J. vanSpronsen, N. M. Verhoeven‐Duif, A. deVreugd, M. Wagenmakers, H. Zweers, H. Dekker, H. R. Waterham, C. D. vanKarnebeek, R. J. A. Wanders, R. A. Wevers

Get full text

Correction: Kuklane et al. A Database of Static Thermal Insulation and Evaporative Resistance Values of Dutch Firefighter Clothing Items and Ensembles. <i>Biology</i> 2022, <i>11</... by Kalev Kuklane, Jakob Eggeling, Maurice Kemmeren, Ronald Heus

Get full text

The Mechanism of RNA Interference and the Transposon Silencing in Caenorhabditis elegans by Marcel Tijsterman, Rena Ketting, Sylvia Fischer, Femke Simmer, Titia Sijen, Kristy Okihara, Bas Tops, Nadine Vastenhouw, Ronald Plasterk

Get full text

Multicenter Evaluation of Morbidity and Predictors of Response to Imiquimod Treatment for Penile Intraepithelial Neoplasia by Ofir Avitan, Laura Elst, Manon Vreeburg, Tynisha Rafael, Katja Jordanova, Niels Graafland, Kees Hendricksen, Bas W.G. van Rhijn, Henk G. van der Poel, Maarten Albersen, Oscar Brouwer

“…Methods: We conducted a collaborative retrospective study involving patients diagnosed with PeIN and treated with IQ between 2010 and 2022 in two high-volume centers in the Netherlands and Belgium. Eligible patients had a confirmed diagnosis of PeIN and a minimum of 6-mo follow-up. …”
Get full text

Bilateral Renal Tumour as Indicator for Birt-Hogg-Dubé Syndrome by P. C. Johannesma, R. J. A. van Moorselaar, S. Horenblas, L. E. van der Kolk, E. Thunnissen, J. H. T. M. van Waesberghe, F. H. Menko, P. E. Postmus

Get full text

Evaluation of a national multidisciplinary meeting for non-tuberculous mycobacterial disease by A. Lemson, T.A. Koster, N. Carpaij, C. Magis-Escurra, M. Boeree, R. Stemkens, R.E. Aarnoutse, A. van Laarhoven, R. van Crevel, J. van Ingen, W. Hoefsloot

Get full text

Immunotherapy in metastatic renal cell carcinoma: Insights from a Dutch nationwide cohort by Hilin Yildirim, Anke Richters, Adriaan D. Bins, Arnoud W. Postema, Maureen J.B. Aarts, Martijn G.H. van Oijen, Patricia J. Zondervan, Katja K.H. Aben

“…We evaluated IO uptake in both first-line and later-line treatment in routine clinical practice in the Netherlands. Patients diagnosed with synchronous mRCC between 2018 and 2022 were identified from the population-based Netherlands Cancer Registry (n = 2621). …”
Get full text

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression by Marcelo Sobral-Leite, Simon P. Castillo, Shiva Vonk, Hendrik A. Messal, Xenia Melillo, Noomie Lam, Brandi de Bruijn, Yeman B. Hagos, Myrna van den Bos, Joyce Sanders, Mathilde Almekinders, Lindy L. Visser, Emma J. Groen, Petra Kristel, Caner Ercan, Leyla Azarang, Jacco van Rheenen, E. Shelley Hwang, Yinyin Yuan, Grand Challenge PRECISION Consortium, Renee Menezes, Esther H. Lips, Jelle Wesseling

Get full text

Remediating cognitive inflexibility in obsessive compulsive disorder and anorexia nervosa neither moderates nor mediates treatment effects: an exploratory study by Boris van Passel, Boris van Passel, Unna N. Danner, Unna N. Danner, Alexandra E. Dingemans, Theo G. Broekman, Lot C. Sternheim, Lot C. Sternheim, Eni S. Becker, Annemarie A. van Elburg, Annemarie A. van Elburg, Eric F. van Furth, Eric F. van Furth, Gert-Jan Hendriks, Gert-Jan Hendriks, Gert-Jan Hendriks, Daniëlle C. Cath, Daniëlle C. Cath

Get full text

Positive associations between mean ambient temperature and involuntary admissions to psychiatric facilities by Noah L. Joore, Marte Z. van der Horst, Eric O. Noorthoorn, Jurriaan F.M. Strous, Fleur J. Vruwink, Sinan Guloksuz, Peter C. Siegmund, Jurjen J. Luykx

“…Methods Involuntary admissions data from 23 psychiatric institutions in the Netherlands were linked to meteorological data from their respective weather stations. …”
Get full text

Investigating the impact of acceptance and commitment therapy for mental healthcare professionals: the effect on patients´ self-stigmatization, a pilot study by Kim L. Helmus, Kim L. Helmus, Kim L. Helmus, Marilon van Doorn, Marilon van Doorn, Mariken B. de Koning, Mariken B. de Koning, Mariken B. de Koning, Inez Myin-Germeys, Frederike N. Schirmbeck, Frederike N. Schirmbeck, Therese A. M. J. van Amelsvoort, Dorien H. Nieman, Dorien H. Nieman, Monique W. M. Jaspers, Monique W. M. Jaspers, Arne Popma, Arne Popma, Lieuwe de Haan, Lieuwe de Haan

Get full text

Transoral robotic surgery for chronic lymphocytic leukaemia in the lingual tonsils: A case report by Lisa W. Lekanne dit Deprez, Alexandra G.L. Toppenberg, Wouter L. Lodder, Robert E. Plaat, Bas Franken, Leonora Q. Schwandt

Get full text

Microbial solutions must be deployed against climate catastrophe by Raquel Peixoto, Christian R. Voolstra, Lisa Y. Stein, Philip Hugenholtz, Joana Falcao Salles, Shady A. Amin, Max Häggblom, Ann Gregory, Thulani P. Makhalanyane, Fengping Wang, Nadège Adoukè Agbodjato, Yinzhao Wang, Nianzhi Jiao, Jay T. Lennon, Antonio Ventosa, Patrik M. Bavoil, Virginia Miller, Jack A. Gilbert

Get full text

Endoscopic vacuum therapy in the upper gastrointestinal tract by Kirsten Boonstra, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Lisanne M. D. Pattynama, Yasmijn J. van Herwaarden, Wietse J. Eshuis, Wietse J. Eshuis, Roos E. Pouw, Roos E. Pouw, Roos E. Pouw

Get full text