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The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration
Published 2024-11-01“…Introduction: Follicular delivery is one of the targeted drug delivery methods aiming to target the hair follicles. …”
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82
Interfacing exogenous stents with human coronary artery by self-assembled coating: designs, functionalities and applications
Published 2024-05-01“…Moreover, we discuss the potential of self-assembled coatings for future development, including intelligent targeted drug delivery, bionic stent coatings, and 3D printed stent coatings. …”
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83
Brain neurons internalise polymeric micron-sized capsules: Insights from in vitro and in vivo studies
Published 2025-04-01“…Nanoengineered encapsulation presents a promising strategy for targeted drug delivery to specific regions in the body. While polyelectrolyte-based biodegradable microcapsules can achieve highly localised drug release in tissues and cell cultures, delivering drugs to intracellular sites in the brain remains a significant challenge. …”
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84
A computational role of blood nanofluid induced by a stenosed artery with porous medium and thermophoretic particle deposition effects
Published 2025-02-01“…This investigation is motivated by the potential of the Casson nanofluids, which exhibit exceptional thermal properties, offering promising applications in medical treatments such as targeted drug delivery and hyperthermia therapy. The present work focuses on understanding the flow behavior of the Casson nanofluids through the stenosed artery under the influence of porosity, thermal radiation, thermophoretic particle diffusion and Stefen blowing. …”
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85
Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience
Published 2025-01-01“…It is a form of targeted drug delivery, which is applicable to treat neuroendocrine tumors. …”
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86
Highly Stable Antitumor Silver-Lipid Nanoparticles Optimized for Targeted Therapy
Published 2025-02-01“…To enhance bioavailability, minimize adverse effects and enable targeted drug delivery AgNPs may be encapsulated in liposomes. …”
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87
Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing
Published 2025-01-01“…These findings reflect the dynamic landscape of HA-based nanoparticle research in cancer therapy, emphasizing advancements in targeted drug delivery, therapeutic efficacy, and multimodal diagnostic approaches to improve overall patient outcomes.…”
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88
Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles
Published 2013-01-01“…During these therapeutic processes, NPrCAP was also expected to provide melanoma-targeted drug delivery system.…”
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89
Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits
Published 2016-01-01“…Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. …”
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90
Microneedling: An Innovative Technique for Gingival Depigmentation
Published 2024-12-01“…Conventionally, collagen induction has been used in the treatment of facial scars and skin rejuvenation, but it is being switched to dental procedures as a new technique for depigmentation, target drug delivery devices, collection of diagnostic fluids, etc.…”
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91
A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy
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92
Interfacial Engineering of Biocompatible Nanocapsules for Near‐Infrared‐Triggered Drug Release and Photothermal Therapy
Published 2025-01-01“…The phase change material core nanocapsules demonstrate great photothermal‐controlled drug release performance and exhibit excellent tumor‐targeting drug delivery performance both in vitro and in vivo via the binding of hyaluronic acid shell on the nanocapsule surface with corresponding receptors on the tumor cell membrane. …”
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93
Double-targeted liposomes coated with matrix metallopeptidase-2-responsive polypeptide nanogel for chemotherapy and enhanced immunotherapy against cervical cancer
Published 2025-02-01“…This study underscores the potential of DPCLG as an advanced, dual-targeting drug delivery system for comprehensive cancer therapy.…”
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94
Epitope-imprinted biomaterials with tailor-made molecular targeting for biomedical applications
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95
Global research trends and emerging hotspots in nano-drug delivery systems for lung cancer: a comprehensive bibliometric analysis (1998–2024)
Published 2025-01-01“…Key research areas encompass “active targeting”, “drug delivery optimization”, “overcoming drug resistance”, “nanocarriers”, and “pulmonary drug delivery”. …”
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96
In vivo imaging and pharmacokinetics of percutaneously injected ultrasound and X-ray imageable thermosensitive hydrogel loaded with doxorubicin versus free drug in swine.
Published 2024-01-01“…Intratumoral injections often lack visibility, leading to unpredictable outcomes such as incomplete tumor coverage, off-target drug delivery and systemic toxicities. This study investigated an ultrasound (US) and x-ray imageable thermosensitive hydrogel based on poloxamer 407 (POL) percutaneously delivered in a healthy swine model. …”
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Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment
Published 2025-01-01“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
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98
Preparation of oat galactolipid and anti-liver cancer effects of oat galactolipid–modified curcumin-loaded liver targeting vesicle
Published 2025-01-01“…IntroductionThe mortality rate for liver cancer is extremely high but clinical treatments have not made much progress, so it is necessary to develop anticancer agents with lower toxicities and more effective liver-targeting drug delivery systems (LTDDSs). At present, LTDDSs mediated by the asialoglycoprotein receptor (ASGPR) show excellent effects at improving the liver-targeting and antitumor effects of drugs. …”
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