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  1. 1541

    Estimating the global health impact of gender-based violence and violence against children: a systematic review and meta-analysis protocol by Joht Singh Chandan, Emmanuela Gakidou, Jaidev Kaur Chandan, Nicholas Metheny, Mariam Khalil, Cory N Spencer, María Jose Baeza, Alexandra Debure, Molly Herbert, Teresa Jewell, Rachel Qian Hui Lim, Sonica Minhas

    Published 2022-06-01
    “…Where possible, variations in associations by subgroup, that is, age, sex or gender, will be explored.Ethics and dissemination Formal ethical approval is not required. …”
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  2. 1542

    SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study by Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum

    Published 2024-12-01
    “…Risk of severe SARS-CoV-2 outcomes was also reduced. Subgroup analyses showed a consistent association between antibody levels and infection risk, by immune status and age. …”
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  3. 1543

    Sleep as a mediator between chronic diseases and depression: a NHANES study (2005–2018) by Ming Tan, Ming Tan, Haihong Zhao, Haihong Zhao, Ruya Nie, Ruya Nie, Pingping Deng, Pingping Deng, Cuixiao Wang

    Published 2025-01-01
    “…Logistic regression, subgroup analysis, restricted cubic spline (RCS) analysis, and mediation analysis were employed to explore the relationship between common chronic diseases and depression, and the mediating role of sleep.ResultsThe adjusted model indicated that stroke (OR = 1.712, 95% CI: 1.399, 2.103), heart disease (OR = 1.419, 95% CI: 1.262, 1.598), diabetes (OR = 1.243, 95% CI: 1.116, 1.386), and hypertension (OR = 1.249, 95% CI: 1.160, 1.346) were associated with an increased probability of depression. …”
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  4. 1544

    Clinical outcomes after immune checkpoint inhibitor-associated acute kidney injury: a cohort study by Vin-Cent Wu, Ting-Ya Yang, Min-Hsiang Chuang, Hong-Min Lin, Heng-Chih Pan, Yun Chou, Jui-Yi Chen

    Published 2025-02-01
    “…After matching, the ICPi-AKI group exhibited a higher risk of all-cause mortality (HR=1.27; 95% CI 1.02 to 1.61), MAKE (HR=3.83; 95% CI 1.72 to 8.40), MACE (HR=1.35; 95% CI 1.03 to 1.75)) compared with the non-ICPi-AKI group. Subgroup analyses confirmed these findings across various patient’s characteristics.Conclusion Individuals with ICPi-AKI are associated with an increased risk of all-cause mortality, MAKE and MACE. …”
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  5. 1545

    Association between the atherogenic index of plasma and non-alcoholic fatty liver disease in Korean pregnant women: secondary analysis of a prospective cohort study by Rong Shuai, Yuxing He, Dongqian Yang, Yingying Zhang, Li Zhang

    Published 2025-01-01
    “…Logistic regression models were used to estimate the relationship between AIP and NAFLD. Subgroup and sensitivity analyses were conducted to explore the stability of this relationship. …”
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  6. 1546

    Eye health risks associated with unclean fuel: a meta-analysis and systematic review by Shi-Hang Chen, Yuan Tang, Song Xue, Song Xue

    Published 2025-01-01
    “…However, no correlation was found between UCF exposure and glaucoma or elevated intraocular pressure [OR 0.96, 95% CI (0.84, 1.10), n = 2]. Subgroup analysis revealed that UCF cooking had an impact on nuclear cataracts [OR 1.98, 95% CI (1.67, 2.33), n = 4]. …”
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  7. 1547

    The effect of exercise intervention on inhibitory function in obese and overweight children and adolescents: a systematic review and meta-analysis by Aona Chen, Chenggen Guo, Shuhua Qu

    Published 2025-01-01
    “…The meta-analysis showed that post-intervention improvements in inhibitory function were significantly greater in the experimental group compared to the control group (SMD = -0.65, 95% CI = -1.01 to -0.29, p < 0.01), indicating a medium effect size. Subgroup analyses indicated that open motor skills (SMD = -0.73, 95% CI = -1.20 to -0.27, p < 0.01), moderate intensity (SMD = -0.80, 95% CI = -1.37 to -0.23, p < 0.01), and long-term regular exercise (SMD = -1.04, 95% CI = -1.47 to -0.62, p < 0.01) were significantly more effective than controls in improving inhibitory function. …”
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  8. 1548

    The role of aging and various surface preparation methods in the repair of nanohybrid composites by Ayşenur Altuğ Yıldırım, Mine Betül Üçtaşlı

    Published 2025-01-01
    “…Results The µSBS values of the non-aged group were higher than those of the 10,000 and 50,000 thermal cycle groups, with no significant differences within the non-aged subgroup (p > 0.05). In the aged groups, significant differences were observed between adhesive application modes and surface treatments. …”
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  9. 1549

    Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis by Bin You, Bin You, Bin You, Bin You, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen

    Published 2025-02-01
    “…RCS analysis confirmed a linear association between both blood manganese and selenium levels and hepatic steatosis prevalence. Subgroup analyses did not reveal statistically significant interactions by age, sex, or obesity status, although associations appeared stronger in younger adolescents.ConclusionElevated blood manganese and selenium levels are associated with a higher prevalence of hepatic steatosis in adolescents. …”
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  10. 1550

    Triglyceride to high density lipoprotein cholesterol ratio and major adverse cardiovascular events in ACS patients undergoing PCI by Shangxun Zhou, Miaohan Qiu, Kexin Wang, Jing Li, Yi Li, Yaling Han

    Published 2024-12-01
    “…Patients in the high quartile TG/HDL-C category demonstrated significantly higher risks for MACE compared to those in the low quartile category, with hazard ratio (HR) [95%confidence interval (CI)] of 1.46 (1.17–1.83); conversely, they showed significantly lower risks for all-cause bleeding compared to their counterparts in the low quartile group, with HR (95%CI) of 0.72 (0.65–0.81). The structure of subgroup analyses remained robust and consistent, with gender being the sole factor interacting with TG/HDL-C specifically in relation to MACE events (P for interaction = 0.037). …”
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  11. 1551

    Association of uveitis with pediatric autoimmune diseases based on a TriNetX study by Alan Y. Hsu, Hou-Ting Kuo, Chun-Ju Lin, Chang-Ching Wei, Ning-Yi Hsia, James Cheng-Chung Wei, Yu-Hsun Wang, You-Ling Li, Chun-Ting Lai, Huan-Sheng Chen, Yi-Yu Tsai

    Published 2024-12-01
    “…Autoimmune patients who had used immunosuppressant medications had increased uveitis risk compared to those who had never used immunosuppressants. Our subgroup analysis also demonstrated a significantly increased uveitis risk associated with specific autoimmune conditions. …”
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  12. 1552

    Burden of early neonatal mortality in Sub-Saharan Africa. A systematic review and meta-analysis. by Natnael Moges, Anteneh Mengist Dessie, Denekew Tenaw Anley, Melkamu Aderajew Zemene, Natnael Atnafu Gebeyehu, Getachew Asmare Adella, Gizachew Ambaw Kassie, Misganaw Asmamaw Mengstie, Mohammed Abdu Seid, Endeshaw Chekol Abebe, Molalegn Mesele Gesese, Yenealem Solomon Kebede, Sefineh Fenta Feleke, Tadesse Asmamaw Dejenie, Natnael Amare Tesfa, Wubet Alebachew Bayih, Ermias Sisay Chanie, Berihun Bantie

    Published 2024-01-01
    “…The Der Simonian and Laird random-effect model was used to calculate the combined magnitude of early neonatal mortality. Besides, subgroup analysis, sensitivity analysis, and meta regression were carried out to identify the source of heterogeneity.…”
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  13. 1553

    A comparison of disseminated intravascular coagulation scoring systems and their performance to predict mortality in sepsis patients: A systematic review and meta-analysis. by Girum Tesfaye Kiya, Gemeda Abebe, Zeleke Mekonnen, Edosa Tadasa, Gedion Milkias, Elsah Tegene Asefa

    Published 2025-01-01
    “…A random-effect meta-analysis was performed with a 95% confidence interval (CI). Subgroup analysis was conducted in view of geographic region and sepsis stages. the protocol was submitted to the Prospective Register for Systematic Reviews (PROSPERO) with an identifier (CRD42023409614).…”
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  14. 1554

    A systematic review and meta-analysis of randomized controlled trials for physical activity among colorectal cancer survivors: directions for future research by Jiayu Mao, Xiaoke Qiu, Yi Zhang, Can Wang, Xueli Yang, Qiuping Li

    Published 2025-01-01
    “…In the meta-analysis, nine of these studies involving 684 participants were included, and results showed that PA interventions have a positive effect on increasing total PA levels in CRC survivors (Z = 2.79, p = 0.005). Results of subgroup analysis revealed that supervised PA interventions (Z = 2.82, p = 0.005) and PA interventions with multiple intervention components (Z = 3.06, p = 0.002) effectively increased total PA levels for CRC survivors. …”
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  15. 1555

    Rituximab-associated adverse events in nephrotic syndrome: A systematic review and meta-analysis by Zixian Yu, Meijin Huang, Yunlong Qin, Xiayin Li, Yueru Zhao, Yuwei Wang, Yumeng Zhang, Anjing Wang, Mei Han, Jin Zhao, Shiren Sun

    Published 2025-01-01
    “…The pooled rate of infusion reactions was 32 % (95 % CI = [19 %, 45 %]) in RCTs and 8 % (95 % CI = [3 %, 13 %]) in retrospective studies. Subgroup analyses demonstrated a lower risk of hematological events in adult NS patients (OR = 0.21, 95 % CI [0.09, 0.51]) and the 1000 mg RTX intervention (OR = 0.21, 95 % CI [0.09, 0.51]). …”
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  16. 1556

    Efficacy of traditional Chinese medicine Cordyceps sinensis as an adjunctive treatment in patients with renal dysfunction: a systematic-review and meta-analysis by Fenfang Wu, Chunhua Xu, Xinlei Si, Fei He, Kang Xu, Yu Zhang, Shan Lin

    Published 2025-01-01
    “…Additionally, area under the curve (AUC) of the summary receiver operating characteristic (SROC) was calculated as 0.88 (95% CI: 0.85–0.90) reflecting prognostic accuracy. Subsequently, subgroup analysis indicated that the clinical efficacy of C. sinensis in northern Chinese patients with RD was superior to that of southern. …”
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  17. 1557

    The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

    Published 2024-12-01
    “…Stepwise multivariate logistic regression was used to identify the related risk factors, and subgroup analyses were performed. A total of 1270 MHD subjects (687 males and 583 females) were included, with an average age of 60 (49.0, 71.0) years. …”
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  18. 1558

    Triglyceride glucose index–body mass index as a predictor of coronary artery disease severity in patients with H-type hypertension across different glucose metabolic states by Lian Wang, Zijin Li, Rui Qiu, Li Luo, Xisheng Yan

    Published 2025-01-01
    “…Results The TyG-BMI was significantly associated with the severity of multi-vessel CAD in hypertensive patients (Odds ratio [OR] 1.043, 95% CI 1.032–1.053). In the diabetic subgroup, after adjusting for risk factors, the risk of multi-vessel CAD in the T3 groups was 3.836-fold (95% CI 1.763–8.347; P = 0.001) higher than in the T1 group, with a non-linear dose–response relationship (P for non-linearity = 0.017). …”
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  19. 1559

    Food taboo practices and associated factors among pregnant women in Sub-Sahara Africa: a systematic review and meta-analysis by Aysheshim Kassahun Belew, Berhanu Mengistu, Ayenew Molla Lakew, Esmeal Ali Muhammad

    Published 2025-02-01
    “…The pooled proportion of food taboo practices reported by the 58 studies was 41% (95% CI: 34, 48%). In the subgroup analysis, the pooled proportion of food taboo practices for studies conducted in urban areas was 40% (95% CI: 32, 48%), while it was 43% (95% CI: 32, 56%) among rural residents. …”
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  20. 1560

    Impact of pubertal timing on growth progression and final height in subjects affected by RASopathies by Federica Tamburrino, Laura Mazzanti, Dino Gibertoni, Concetta Schiavariello, Annamaria Perri, Eleonora Orlandini, Cesare Rossi, Marco Tartaglia, Marcello Lanari, Emanuela Scarano

    Published 2025-01-01
    “…This study aimed to evaluate the timing and progression of puberty and its impact on growth and final height in patients with RASopathies.Subjects and methodsA retrospective longitudinal study was conducted involving 103 patients with molecularly confirmed RASopathies. A subgroup of 40 patients who had completed pubertal development was analyzed. …”
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