Association between the triglyceride-glucose index and liver fibrosis in adults with metabolism-related fatty liver disease in the United States: a cross-sectional study of NHANES... by Yuou Ying, Yuan Ji, Ruyi Ju, Jinhan Chen, Mingxian Chen

“…Elevated TyG levels showed a positive correlation with significant fibrosis, with an odds ratio (OR) exceeding 1 when the TyG index was above 8.054. Subgroup analyses stratified by sex, age, and body mass index (BMI) revealed differences after adjusting for confounders. …”
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Correlations among PPAR𝜸, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Valerio Pazienza, Francesca Tavano, Giorgia Benegiamo, Manlio Vinciguerra, Francesca Paola Burbaci, Massimiliano Copetti, Fabio Francesco di Mola, Angelo Andriulli, Pierluigi di Sebastiano

“…Furthermore, high levels of DNMT3B expression were significantly associated with a lower mortality in the whole population (HR=0.485; 95%CI=0.262–0.895, 𝑃=0.02) and in the subgroup of patients without perineural invasion (HR=0.314; 95%CI=0.130–0.758; 𝑃=0.01), while such association was not observed in patients with tumor invasion into perineural structures (𝑃=0.70). …”
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Efficacy of combined colorectal cancer treatment in senile patients by P. V. Tsarkov, D. R. Markaryan, V. M. Nekoval

“…In group of patients with III and IV stages of CRC who received postoperative adjuvant therapy, the tendency to higher total survival was noted, however only cancer-specific survival scores had statistically significant differences in this subgroup. Conclusions. Multidisciplinary approach to CRC treatment provides achievement of satisfactory postoperative mortality in senile patients (4.9% versus predicted 13.2%) along with satisfactory total and cancer-specific 5-year survival rate. …”
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Predicting 28-day all-cause mortality in patients admitted to intensive care units with pre-existing chronic heart failure using the stress hyperglycemia ratio: a machine learning-... by Xiao-han Li, Xing-long Yang, Bin-bin Dong, Qi Liu

“…SHR was independently associated with 28-day all-cause mortality, with an unadjusted hazard ratio (HR) of 1.45 (P < 0.001) and an adjusted HR of 1.43 (P < 0.001). Subgroup analysis found that none of the potential risk factors, such as demographics, comorbidities, and drugs, affected the relationship (P for interaction > 0.05). …”
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Retrospective Analysis Comparing Lung-RADS v2022 and British Thoracic Society Guidelines for Differentiating Lung Metastases from Primary Lung Cancer by Loredana Gabriela Stana, Alexandru Ovidiu Mederle, Claudiu Avram, Felix Bratosin, Paula Irina Barata

“…Statistical analyses compared the sensitivity and specificity of Lung-RADS and BTS guidelines in distinguishing metastases from primary lung cancer. Subgroup analyses were conducted based on nodule characteristics. …”
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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…We assessed the incidence of ROP at any stage, severe ROP, adverse events and mortality. Subgroup analyses were performed for each prophylactic agent. …”
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Isolation and Genomic Characterization of a Novel Porcine Reproductive and Respiratory Syndrome Virus 1 from Severely Diseased Piglets in China in 2024 by Shuai Yang, Meng Cui, Chen Li, Ming Qiu, Xiaoyang Zhu, Yanhan Lin, Yifan Meng, Yuejia Qiu, Wenhao Qi, Hong Lin, Wanglong Zheng, Jianzhong Zhu, Kewei Fan, Nanhua Chen

“…Furthermore, a genome-based phylogenetic tree supported that the AHEU2024-2671-like isolates form a novel subgroup within subtype 1. Overall, this study not only supported the idea that PRRSV-1 is rapidly evolving in Chinese swine herds, but also pulled the alarm that novel PRRSV-1 isolates with potentially increased pathogenicity might already exist in China, although they are still rarely detected among Chinese pigs.…”
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Patient education materials for non-specific low back pain and sciatica: a protocol for a systematic review and meta-analysis by Kris Aubrey-Bassler, Amanda Hall, Michelle Swab, Bradley Furlong, Andrea Pike, Holly Etchegary, Georgia Darmonkow

“…Likewise, analyses of short-term (less than 6 months) and long-term (6 months or greater) follow-up will be performed separately. Subgroup analyses will be performed on non-specific low back pain, sciatica and mixed populations.Ethics and dissemination Ethical approval is not required for this review. …”
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The complex relationships among self-acceptance, perceived social support, drug use stereotype threat, and subthreshold depression in people with substance use disorder: exploring... by Yongqiu Li, Rufang Wang, Jun Liu, Zuoliang Li, Yinghua Zhou

“…Results exploring the buffering effect of perceived social support by subgroup showed that the buffering effect of perceived social support on subthreshold depression was most pronounced in the HIV-negative and and female groups. …”
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Efficacy and Safety of Transcutaneous Electrical Acupoint Stimulation for Postoperative Pain: A Meta-Analysis of Randomized Controlled Trials by Dan Wang, Hongshuo Shi, Zhenguo Yang, Wenbin Liu, Lu Qi, Chengda Dong, Guomin Si, Qi Guo

“…The current results suggested that application of TEAS showed obvious superiority in reducing VAS scores (SMD = −1.51, 95% CI = −2.20∼−0.82, I2 = 96%). Subgroup analysis was performed according to open surgery and minimally invasive surgery. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…The primary outcomes included hypertension, palpitations, and chest pain, with pooled effect estimate reported as proportions and odds ratios (ORs) with 95% confidence intervals (CIs). Sensitivity and subgroup analysis were performed to assess the robustness of the results and to identify sources of heterogeneity. …”
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Influence of TMPRSS6 genotype on iron status parameters in stable COPD patients by Trtica Marko, Novaković Ivana, Dopsaj Violeta, Milenković Branislava, Janković Jelena, Dimić-Janjić Sanja, Dopuđa-Pantić Vesna, Martinović Jelena, Jovičić Snežana

“…Statistical but not clinical difference in EPO levels was observed in a subgroup of patients. In addition to promoting erythropoiesis, EPO may regulate hepcidin levels and thus influence the development of iron deficiency and/or anaemia. …”
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Associations of dietary oxidative balance score with sarcopenia in adults: an NHANES-based cross-sectional study by Qiang Zhou, Shang Zhou, Zuo-xi Chen, Wu-jie Zhou, Jia Su, Yong Wang

“…The effect sizes and CIs to the left and right of the inflection point were 1.62 (95% CI: 1.09 to 2.41, P = 0.016) and 0.97 (95% CI: 0.95 to 0.98, P < 0.001), respectively. Subgroup analyses confirmed the stability of this relationship across various demographic and health-related variables. …”
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The Association between Serum Level of Vitamin D and Inflammatory Biomarkers in Hospitalized Adult Patients: A Cross-Sectional Study Based on Real-World Data by Xiaomin Zhang, Zhiqi Chen, Yi Xiang, Yiquan Zhou, Molian Tang, Jun Cai, Xinyi Xu, Hongyuan Cui, Yi Feng, Renying Xu

“…Each standard deviation (≈7.4 ng/mL) increase in vitamin D was associated with a decrease in WBC by 0.13 × 109/mL (95% CI: 0.2 × 109/mL, 0.06 × 109/mL) and 0.62 mg/L (95% CI: 0.88 mg/L, 0.37 mg/L) for CRP. Subgroup analysis and sensitivity analysis (excluding those whose eGFR <60 ml/min/1.73 m2, those whose daily calorie intake <1,000 kcal, and those who were recruited from Xin Hua hospital) generated similar results. …”
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Impact of acupuncture on mortality in patients with disabilities and newly diagnosed heart failure: a nationwide cohort study by Hyungsun Jun, Dasol Park, Jae-Uk Sul, Moon Joo Cheong, Haerim Kim, Inae Youn, Jungtae Leem, Jungtae Leem, Jungtae Leem

“…Higher acupuncture doses were associated with a greater reduction in mortality, with the highest dose group showing a 36% lower risk (adjusted HR 0.64, 95% CI 0.58–0.69) than those in the non-exposed group. The subgroup analysis showed a consistent reduction in mortality across most groups, particularly in women, older adults, higher-income individuals, and those with severe disabilities.ConclusionThis study suggests that acupuncture exposure is associated with reduced mortality in people with disabilities who are newly diagnosed with heart failure. …”
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Validity of the Systemic Lupus Erythematosus Disease Activity 2000-Glucocorticoid Index, its association with the Physician Global Assessment, and potential association with diseas... by Basma M. Medhat, Lobna A. Maged, Doaa A. Teleb, Sally S. Mohamed, Angie Y. Afifi, Dina M. T. Koptan, Walaa Abdelrahman, Dalia Dorgham, Eman Hany Elsebaie, Naglaa Afifi, Sahar A. Ahmed, Mervat E. Behairy, Hala Ramadan

“…The association’s strength between both the SLEDAI-2 KG and PGA and SLEDAI-2 K declined among low activity-patients (SLEDAI-2 K < 6) [(r = 0,4; p < 0.001) (r = 0.2; p = 0.02), respectively], and the SLEDAI-2 KG and PGA were not associated in this subgroup (r: 0.07, p = 0.4). The agreement’s strength between the SLEDAI-2 K and PISCOS-PGA was weak (kappa = 0.17, p < 0.001). …”
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Evaluating the overall renal outcomes of sodium-glucose cotransporter-2 (SGLT2) inhibitors in patients with chronic kidney disease (CKD) by Min-Jia Cao, Ting-Ting Liang, Li Xu, Fang-Hong Shi

“…Abstract Background Our meta-analysis fills gaps by assessing sodium-glucose cotransporter-2 (SGLT2) inhibitors’ renal outcomes in chronic kidney disease (CKD) patients including long-term effects and the subgroup analyses of estimated glomerular filtration rate (eGFR) values and follow-up times. …”
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Psoriasis increases the risk of Sjögren’s syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis by Zijian Kang, Yu Du, Ran Cui, Qian Wang, Miao Chen, Yu-Hsun Wang, James Cheng‐Chung Wei, Sheng-Ming Dai

“…Upon adjustment for multiple confounding factors, the risk of developing SS in the psoriasis group was 50% higher in the psoriasis group than the non-psoriasis group (hazard ratio [HR] 1.50, 95% confidence interval [CI] 1.42–1.58). Subgroup analyses confirmed the elevated risk of SS associated with psoriasis. …”
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Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database by Wenquan Ding, Rui La, Shenghao Wang, Zhiyuan He, Dinghua Jiang, Zhigang Zhang, Hao Ni, Wu Xu, Lixin Huang, Qian Wu, Qian Wu

“…This association was remarkably consistent across subgroups by age, sex, body mass index (BMI), alcohol consumption, hypertension, diabetes, and smoking status. …”
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A mediation analysis of meteorological factors on the association between ambient carbon monoxide and tuberculosis outpatients visits by Tianfeng He, Tianfeng He, Xujun Qian, Jing Huang, Guoxing Li, Xinbiao Guo

“…Similarly, the maximum cumulative lag effect of CO exposure was 1.781 (RR = 1.781, 95%CI: 1.157–2.742, lag 0–15 days). Subgroup analysis revealed a significant effect of CO exposure in males (RR = 1.090, 95%CI: 1.009–1.777, lag 0–3 days), females (RR = 1.101, 95%CI: 1.014–1.195, lag 0–3 days), younger individuals (RR = 1.097, 95%CI: 1.022–1.178, lag 0–2 days), and during the warm season (RR = 1.012, 95%CI: 1.002–1.022, lag 0–4 days). …”
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