The association between neutrophil to high-density lipoprotein cholesterol ratio and gallstones: a cross-sectional study by Yinkang Wang, Xingchen Shang, Yinchao Zhang, Yu Zhang, Wei Shen, Qian Wu, Wenyi Du

“…Data were analyzed using a variety of statistical techniques, such as univariate analysis, multivariate analysis, and subgroup analysis. In addition, a receiver operating characteristic curve (ROC) was used to determine the predictive power of the index for the risk of gallstone prevalence. …”
Get full text

Investigating the optimal maximum diameter of benign thyroid nodules for thermal ablation on the basis of complete disappearance rate by Shi-Liang Cao, Wan-Ying Shi, Zhen-Long Zhao, Ying Wei, Na Yu, Jie Wu, Li-Li Peng, Yan Li, Ming-An Yu

“…Restricted cubic spline indicated that an MD of 25.0 mm was the optimal threshold of BTNs for TA, which was confirmed by subgroup logistic regression analysis. Compared with BTNs with MD ≤ 25.0 mm, those with MD > 25.0 mm had a greater complication rate (6.5% vs. 2.4%, p = 0.012).Conclusions The MD of BTNs was negatively correlated with complete disappearance after TA; an MD > 25.0 mm indicated a reduced likelihood of complete disappearance compared with an MD ≤ 25.0 mm. …”
Get full text

The influence of baseline platelet on mortality risk in stroke and cancer patients: a cross-sectional analysis of the NHANES database by Yuqi Pei, Wei Ouyang, Peiyun Qi, Zhongjie Yan, Yaoru Li, Xiangjian Zhang, Cong Zhang, Lili Cui

“…Mortality in higher-platelet group (> 209 × 109/L, n = 57) was decreased than lower-platelet group (≤ 209 × 109/L, n = 56) (Model 1 HR 0.43, 95% CI 0.24—0.77, p = 0.005) (Model 2 HR 0.58, 95% CI 0.35—0.96, p = 0.03). Subgroup analyses showed no significant interaction between platelet and age, sex, BMI, WBC and neutrophil. …”
Get full text

Sick leave and disability pension in patients with chronic hepatitis C compared with a matched general population: a nationwide register study by Matti Sällberg, Katharina Büsch, Fredrik Hansson, Michelle Holton, Martin Lagging, Johan Westin, Jan Kövamees, Jonas Söderholm

“…The secondary outcome was workdays lost per subgroup of patients with chronic HCV.Results In 2012, 14% of the HCV patients had ≥1 registered sick leave episode compared with 10% in the matched comparator cohort. …”
Get full text

Impact of Peracetic Acid on the Dynamic Cyclic Fatigue of Heat-Treated Nickel-Titanium Rotary Endodontic Instrument by Suhad Jabbar Hamed Al-Nasrawi, Zuha Ayad Jaber, Nibrass Talib Al-Quraine, Abtesam Imhemed Aljdaimi, Sattar Jabbar Abdul-Zahra Al-Hmedat, Saleh Zidan, Julfikar Haider

“…Each type was divided into three subgroups (n = 6 for each file type): (1) untreated instruments; (2) files immersed in 0.002% PAA; and (3) files immersed in 0.35% PAA. …”
Get full text

Persistent lipoprotein(a) exposure and its association with clinical outcomes after acute myocardial infarction: a longitudinal cohort study by Zhenwei Wang, Junnan Tang, Qian Shi, Lijuan Fang, Naifeng Liu, Jinying Zhang

“…Multivariate Cox regression, subgroup analysis and sensitivity analysis assessed the association between Lp(a) trajectories and major adverse cardiovascular and cerebrovascular events (MACCE), cardiovascular death, non-fatal MI, non-fatal stroke, unplanned revascularization, and all-cause death.Results Over a median 50-month follow-up, 343 (35.70%) patients encountered MACCE, and 210 (18.70%) died, including 126 (11.20%) from cardiovascular causes. …”
Get full text

Arthroscopic all-inside wrapping repair of lateral meniscus bucket-handle tears: clinical and imaging outcomes by Kun-Hui Chen, Hsuan-Hsiao Ma, Alisan Fu, Hsin-Yi Wang, Hsiao-Li Ma, En-Rung Chiang

“…MRI evaluations at 6 months postoperatively revealed complete healing in 64.7% (22/34; 95% CI: 47.9–79.5%), partial healing in 23.5% (8/34), and failure to heal in 12.5% (4/34, including the two re-tear cases). Subgroup analyses indicated no significant difference in the IKDC scores between patients with complete healing and those with partial healing on MRI (85.5 ± 7.9 vs. 82.3 ± 8.5; p = 0.53). …”
Get full text

Association Between the Albumin-Bilirubin (ALBI) Score and All-cause Mortality Risk in Intensive Care Unit Patients with Heart Failure by Jiuyi Wang, Kai Wang, Guibo Feng, Xin Tian

“…This relationship was consistently observed across most subgroups, except for using or not using inotropes or vasopressors, different ages, different creatinine levels. …”
Get full text

Comparison of pediatric injury patterns before and during the COVID-19 pandemic in Korea: a retrospective study by Geom Pil Nam, Woo Sung Choi, Jin-Seong Cho, Yong Su Lim, Jae-Hyug Woo, Jae Ho Jang, Jea Yeon Choi

“…We analyzed the injury patterns of pediatric patients aged 0 to 15 years. Subgroup analysis was conducted by age group in children aged 7 to 15 years, 1 to 6 years, and <1 year. …”
Get full text

Analysis of antimicrobial resistance and clinical features of Staphylococcus aureus-infected bone and joint infections in children by Xingguang Chen, Ting Zhuang, Chengda Zou, Yao Liu, Qian Sun, Mengxia Li, Wen Zheng, Chaochen Zhao, Xiaodong Wang

“…However, patients with positive X-ray findings were more likely to have MRSA infections (p = 0.033). Subgroup analysis revealed that children older than 48 months with positive X-ray results were more likely to have MRSA (p = 0.048). …”
Get full text

Comparing the Prognostic Value of PTEN and Akt Expression with the Mitotic Activity Index in Adjuvant Chemotherapy-Treated Node-Negative Breast Cancer patients aged <55 years by Emiel A. M. Janssen, Håvard Søiland, Ivar Skaland, Einar Gudlaugson, Kjell H. Kjellevold, Arne Nysted, Jon-Arne Søreide, Jan P. A. Baak

“…Patients with combined MAI < 3 & PTEN-positivity had 100% survival. The small subgroup of MAI < 3 patients that died were PTEN-negative.…”
Get full text

Can fecal calprotectin be used as a biomarker of non-alcoholic fatty liver disease in obese adolescents? by Büşra Tetik Dinçer, Ayşe Merve Usta, Alev Kural, Nazlı Helvacı, Ahmet Uçar, Nafiye Urgancı

“…Obese adolescents were divided into two subgroups: obese adolescents (n = 11) and Obese + NAFLD group (n = 20). …”
Get full text

The double-edged sword of statins in intracerebral hemorrhage patients: a systematic review and meta-analysis by Zheng Li, Wen-qi Xu, Jiao-qi Wang, Jia-hui Yang, Xiao-hua Shi, Cheng-bing Wang, Zhong-xin Xu, Jin-lan Jiang

“…Our meta-analysis showed that statins significantly reduced overall mortality in patients with ICH (OR: 0.61; 95% CI: 0.51–0.73; I2 = 87%; p &lt; 0.01). Subgroup analyses further demonstrated lower mortality in ICH patients treated with statins compared to those not treated, including in the propensity score matching (PSM) group (OR: 0.59; 95% CI: 0.48–0.74; I2 = 90%; p &lt; 0.01), the prospective cohort study (PCS) group (OR: 0.56; 95% CI: 0.40–0.77; I2 = 89%, p &lt; 0.01), and the retrospective cohort study (RCS) group (OR: 0.64; 95% CI: 0.51–0.81; I2 = 87%, p &lt; 0.01).ConclusionOur meta-analysis of 30 studies suggests that statin use may be associated with improved mortality and functional outcomes in patients with intracerebral hemorrhage (ICH).Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42023493063.…”
Get full text

Major and minor perineural invasion in salivary gland cancer by Fei Liu, Yinglin Chu, Qizhe Zheng, Yunshuang Hu, Yiyi Wang, Lu Qin, Shuaikun Fu, Suping Wang

“…In the Cox model for locoregional control, patients with minor and major nerve PNI exhibited HRs of 1.64 [95% CI: 1.17-2.78] and 1.65 [95% CI: 1.03-2.90], respectively, when compared to those without PNI. Subgroup analyses revealed that the incorporation of chemotherapy into radiotherapy did not significantly modify the risk of mortality or locoregional recurrence in comparison to patients treated with radiotherapy alone, irrespective of PNI classification.ConclusionBoth minor and major nerve PNI exerting comparable influences on prognosis, the adjunctive use of chemotherapy in combination with RT did not yield improvements in overall survival or locoregional control, irrespective of PNI status.…”
Get full text

Steroid use for established bronchopulmonary dysplasia: study protocol for a systematic review and meta-analysis by Roy K Philip, Joanna Seliga-Siwecka, Eduardo Villamor, Maria Pierro, Niazy Al Assaf, Sabina Strashun, Roberto Chioma, Kinga Zielińska, Krzysztof Włodarczyk

“…We will account for the expected heterogeneity by using a random-effects model. We will perform subgroup analysis based on the a priori determined covariate of interest.Ethics and dissemination Systematic reviews are exempted from approval by an ethics committee. …”
Get full text

Extracellular volume fraction and native T1 mapping in diabetic cardiomyopathy: a comprehensive meta-analysis by Ahmed Marey, Ali Alabdullah, Hossam Ghorab, Fatima Ali, Jawdat Abdulla, Akhil Narang, Muhammad Umair

“…Meta-regression assessed the correlation between ECV and HbA1C. Sensitivity and subgroup analyses were performed to explore heterogeneity. …”
Get full text

Prevalence of diabetic retinopathy and its associated factors among adults in East African countries: A systematic review and meta-analysis. by Habtamu Wagnew Abuhay, Tigabu Kidie Tesfie, Meron Asmamaw Alemayehu, Muluken Chanie Agimas, Getaneh Awoke Yismaw, Gebrie Getu Alemu, Nebiyu Mekonnen Derseh, Bantie Getnet Yirsaw

“…Potential heterogeneity was tested using the I-squared statistic. Subgroup analysis, sensitivity analysis, and meta-regression analysis were also performed. …”
Get full text

Association between metabolic score for visceral fat index and BMI-adjusted skeletal muscle mass index in American adults by Yifan Zhou, Xiangjie Su, Haitao Tan, Jun Xiao

“…The final adjusted model from the weighted multivariable linear regression indicated that METS-VF was negatively associated with SMI, with a coefficient of β = -0.13 (95% CI: -0.14, -0.12; P < 0.001). Subgroup analyses further demonstrated that this negative association was consistent across different populations. …”
Get full text

Association between Chinese visceral adiposity index and risk of new-onset hypertension in middle-aged and older adults with prediabetes: evidence from a large national cohort stud... by Lanlan Li, Lanlan Li, Linqiang Xi, Qianhui Wang

“…The area under the receiver operating characteristic (ROC) curve (AUC) demonstrated that CVAI exhibited superior performance in discriminating individuals at heightened risk of hypertension compared to other obesity-related indices (p &lt; 0.001). A subgroup analysis revealed that age may modulate the relationship between CVAI and new-onset hypertension, with a more pronounced interaction observed among participants below 60 years of age (P for interaction: 0.026).ConclusionElevated CVAI levels were significantly associated with an increased risk of developing hypertension. …”
Get full text

Web-based interventions for pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis protocol by Ping Xu, Wei Zhang, Xiaojuan Wang, Dan Dan Chen, Pingping Guo, Yin Jin, Zhenzhen Xiang, Minna Mao, Qiong Zheng, Suwen Feng

“…The overall meta-analyses for each of the interested outcomes will be performed if the outcome data are sufficient and provides similar effect measures, as well as subgroup analyses for glycaemic control indicators based on the different types of intervention format, interactivity and technology. …”
Get full text