Incidence Density Rate of Neonatal Mortality and Predictors in Sub-Saharan Africa: A Systematic Review and Meta-Analysis by Zebenay Workneh Bitew, Ayinalem Alemu, Ermias Getaneh Ayele, Desalegn Abebaw Jember, Michael Tamene Haile, Teshager Worku

“…Fixed and random effect models were used to compute pooled estimates. Subgroup and sensitivity analyses were performed. Results. …”
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Steroid-Refractory Acute GVHD: Predictors and Outcomes by Jason R. Westin, Rima M. Saliba, Marcos De Lima, Amin Alousi, Chitra Hosing, Muzaffar H. Qazilbash, Issa F. Khouri, Elizabeth J. Shpall, Paolo Anderlini, Gabriela Rondon, Borje S. Andersson, Richard Champlin, Daniel R. Couriel

“…We sought to identify a subgroup of patients less likely to benefit from initial therapy with corticosteroids as well as the impact of response on day 14 on outcome. …”
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Intrauterine metformin exposure and adiposity outcomes in children: a systematic review and meta-analysis by George Tomlinson, Jill Hamilton, Kellie E Murphy, Jennifer Fu, Najla Tabbara, Denice S Feig

“…When stratified by maternal diagnosis, no difference in BMI was found in the diabetes and obesity subgroups, while in the polycystic ovary syndrome subgroup metformin-exposed children were heavier than non-exposed peers (SMD 0.31; 95% CI: 0, 0.62; low certainty). …”
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Exploration of whether socioeconomic factors affect the results of priority setting partnerships: updating the top 10 research priorities for the management of Parkinson’s in an in... by Michael Lawton, Inga Liepelt-Scarfone, Rejko Krüger, Michele T Hu, Christine Lo, Charlotte Woodward, Francesca Bowring, Jessica Welch, Patricia Sulzer, Anne-Marie Hanff

“…Finding the best form of physiotherapy for PwP was the number one priority across the majority of analyses. HCP were the only subgroup not to place physiotherapy in the top 10. …”
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Green space is associated with new-onset stroke among Chinese middle-aged and older adults: data from China Health and Retirement Longitudinal Study (CHARLS) by Qiong Lu, Qiong Lu, Cheng Lian, Xinglin Chen, Xinglin Chen

“…Multivariate Cox regression models were constructed to investigate the association between green space and stroke risk. Subgroup analysis was also performed.ResultsA total of 13,696 participants with a mean age of 59.3 ± 9.3 years were included. …”
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The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus by Rujie Zheng, Wenjuan Song, Jie Lu, Mingyue Yuan, Xiaotong Sun, Chengzhi Lu

“…Dapagliflozin showed the greatest difference for reduction of aortic aneurysm incidence (HR, 95% CI 0.84, 0.80–0.95, p = 0.011). Subgroup analysis indicated that use of SGLT2i lower the risk of aortic aneurysm in some subgroups of T2DM patients. …”
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Exploring the association between pro-inflammatory diets and chronic liver diseases: evidence from the UK Biobank by Lili Pan, Lili Pan, Zhengrong Xu, Yining Li, Guoen Cai, Haibing Gao, Shenglong Lin

“…Competing risk analyses, which accounted for cirrhosis, liver cancer, and death, supported these findings. Subgroup analyses confirmed the robustness of the DII's association across various demographic and lifestyle factors. …”
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Diagnostic and prognostic values of tsRNAs in lung cancer: a meta-analysis by Cheng Tang, Su-Xia Sun, Chao Gu, Chao-Juan Li, Jin Xu, Ke-Lei Su, Dan-Dan Zhou, Kuai Yu, Qing-Ling Xiao, Xiao-Li Chen

“…Our results indicated that the combined DOR of total tsRNAs for LC diagnosis was 7.32; the AUC was 0.81. Subgroup analysis revealed that high levels of tsRNAs in serum had good diagnostic efficacy (DOR = 16.56, AUC = 0.88). …”
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A systematic review and meta-analysis of exercise-based intervention to prevent gestational diabetes in women with overweight or obesity by Teresa E. Santa Cruz, Cristina Sarasqueta, Juan Carlos Muruzábal, Eukene Ansuategui, Olga Sanz

“…Exercise did not reduce the risk of GDM: RR, 0.82 [95% CI, (0.58–1.17)] but subgroup analysis shows a significant benefit among patients adhering to the programs: RR, 0.56 [95% CI, (0.40–0.78)] and no effect among non-adherents: RR, 1.11 [95% CI, (0.82–1.50)]. …”
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Systematic review of the application of the Kidney Failure Risk Equation and Oxford classification in estimating prognosis in IgA Nephropathy by M. P. Toal, R. Fergie, M. P. Quinn, C. J. Hill, C. O’Neill, A. P. Maxwell

“…Both the KFRE and the IgAN Risk Prediction (IRP) tool (incorporating the OC) were highly accurate at predicting ESRD with a C-statistic of 0.90 and 0.91, respectively. Subgroup analysis demonstrated improved performance of IRP over KFRE in discrimination for individuals with preserved eGFR (> 60 ml/min/1.73 m2) at baseline. …”
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The Role of SGLT2 Inhibitors in Heart Failure: A Systematic Review and Meta-Analysis by Vasiliki Tsampasian, Ranu Baral, Rahul Chattopadhyay, Maciej Debski, Shruti S Joshi, Johannes Reinhold, Marc R Dweck, Pankaj Garg, Vassilios S Vassiliou

“…For the total population, SGLT2 inhibitors reduced the risk of all-cause mortality (HR: 0.83; 95% CI: 0.75–0.91; I2 0%), hospitalisation for HF (HR: 0.68; 95% CI: 0.61–0.75; I2: 0%), CV death (HR: 0.82; 95% CI: 0.74–0.92; I2: 0%), and hospitalisation for HF or CV death (HR: 0.72; 95% CI: 0.66–0.78; I2: 0%). Subgroup analyses of the total population according to the diabetes status showed that SGLT2 inhibitors significantly reduced the risk of hospitalisation for HF (HR: 0.68; 95% CI: 0.61, 0.75; I2: 0%), as well as the risk of hospitalisation for HF or CV death (HR: 0.72; 95% CI: 0.66, 078; I2: 0%) and CV death (HR: 0.82; 95% CI: 0.74, 0.91; I2: 0%). …”
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Biologic Therapies for Chronic Obstructive Pulmonary Disease: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials by Tyler Pitre, Daniel Lupas, Jasmine Mah, Matthew Stanbrook, Alina Blazer, Dena Zeraatkar, Terence Ho

“…Dupilumab probably has no meaningful effect on FEV1 compared to placebo (MD 0.07 [95% CI 0.02 to 0.13]) (moderate certainty). However, in the subgroup of patients with blood eosinophils ≥300/mcL, both tezepelumab (MD 0.15 [95% CI 0.05 to 0.26]) and dupilumab (MD 0.13 [95% CI 0.06 to 0.19]) probably improved FEV1 above the MCID.Conclusion Dupilumab is effective at improving patient-relevant outcomes in COPD with higher eosinophil levels. …”
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Significance of N-terminal pro-B-type natriuretic peptide levels in lung cancer by Sinem İnan, Semra Bilaçeroğlu, Burcu Uludağ Artun

“…When lung cancer and control groups were compared globally or as subgroups with comorbidities, NT-proBNP levels did not show meaningful differences. …”
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Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study by Lian-Zhen Huang, Ze-Bin Ni, Wei-Feng Huang, Li-Ping Sheng, Yan-Qing Wang, Jin-Yan Zhang

“…RCS model demonstrated a non-linear dose-response relationship between LE8 score and health factors score with MASLD, while a linear relationship was found between health behaviors score and MASLD. Subgroup analysis showed a consistent negative correlation between LE8 score and MASLD, and sensitivity analysis validated the reliability of these findings. …”
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Integrative analysis of anoikis-related prognostic signature to evaluate the immune landscape and predict therapeutic response in stomach adenocarcinoma by Ziyi Zhou, Lanlan Yang, Yuan Fang, Rongzhong Xu, Xi Wang, Yuli Wang, Zhihong Fang

“…The prognostic signature indicated that the low-risk subgroup had better outcomes and significant correlations with tumor microenvironment, immune landscape, immunotherapy response, and drug sensitivity. …”
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Association of Immune Nutrition Indices with the Risk of All-Cause Mortality and Cardiovascular Mortality in Patients with Heart Failure in the NHANES (1999–2018) by Feifei Zhang, Yuetao Xie, Litian Liu, Huiliang Liu, Ohua Feng, Yingxiao Li, Yi Dang

“…Weighted Cox proportional hazards models were employed to assess the independent association of different immune nutrition indices with mortality risk, alongside subgroup analyses and Kaplan–Meier survival curves. …”
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Efficacy of acupuncture for primary osteoporosis: a systematic review and meta-analysis of randomized controlled trials by Tianyi Ma, Tiantian Zhang, Le Zhang, Haoming Zhao, Ke Liu, Jianjun Kuang, Liang Ou

“…Data were synthesized using a random-effects meta-analysis model, and the observed heterogeneity was investigated using subgroup analyses. Study quality was appraised using the Cochrane RoB 2 tools, and the quality of the aggregated evidence was evaluated using the GRADE guidelines. …”
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Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World S... by Chia-Yi Lee, Hung-Chi Chen, Shun-Fa Yang, Yi-Jen Hsueh, Chin-Te Huang, Jing-Yang Huang, Ie-Bin Lian, Chao-Kai Chang

“…Moreover, the amplitude of astigmatism change was significantly lower in the topographic group (<i>p</i> = 0.002). In the subgroup analysis, UDVA and residual astigmatism were significantly better in the topographic group than in the manifest group (both <i>p</i> < 0.05). …”
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Prognostic impact of tumor size on cancer-specific survival for postoperative WHO grade II oligodendroglioma: a SEER-based study by Qin Lu, Yongyan Wu, Yonglin Xie, Shuxu Yang, Hongchuan Jin

“…The optimal cut-off value of tumor size was determined by X-tile analysis and verified by multivariate analyses. Subsequently, Subgroup analyses were performed based on tumor size.Result676 OG/II patients were enrolled in our study. …”
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Low Fifth-Minute Apgar Score Analysed According to Robson Ten Group Classification at a Tertiary Hospital in Nigeria by Olakunle Makinde, Benjamin O. Awotundun, Nkencho Osegi

“…Neonates were classified by the corresponding Robson group with subgroup modification of their mothers. Data was analyzed using IBM SPSS Statistics version 25. …”
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