Positive Association between the Triglyceride-Glucose Index and Hyperuricemia in Chinese Adults with Hypertension: An Insight from the China H-Type Hypertension Registry Study by Chao Yu, Tao Wang, Wei Zhou, Lingjuan Zhu, Xiao Huang, Huihui Bao, Xiaoshu Cheng

“…The TyG index had significant correlations between male patients and hyperuricemia (OR = 2.01) by subgroup analysis. Conclusion. Positive associations were found between the TyG index and serum uric acid and between the TyG index and hyperuricemia in adults with hypertension. …”
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Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus by Yan Yang, Chao Yuan, Shu-qun Shen, Xue-er Wang, Qing-hua Mei, Wen-qing Jiang, Qin Huang

“…N-Methyl-D-aspartate (NMDA) receptors are a subgroup of the glutamate receptor family, whose NR2A subunit was found on neuronal cells (anti-NR2A) in NPSLE patients with different types of epilepsy. …”
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Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study by Yuan-Zhuo Du, Jia-Qing Yang, Ji-Ming Yao, Chi-Teng Zhang, Yi-Fu Liu

“…Multivariable logistic regression models were used to quantify the relationship between NHR and kidney stone occurrence. Subgroup analyses were conducted to explore variations in effect.ResultsA total of 2,351 participants (9.93%) were diagnosed with kidney stones, and their mean age was 47.20 ± 0.26 years. …”
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Continuation of Aspirin Therapy before Cataract Surgery with Different Incisions: Safe or Not? by Qingjian Li, Yiwen Qian, Yu Zhang, Gaoyuan Sun, Xian Zhou, Zhiliang Wang

“…Although corneal edema was greater in clear corneal incision cases than that of scleral tunnel incision cases (22.5% versus 12.0%, p=0.009), subconjunctival hemorrhage was greater in scleral tunnel incision cases (14.9% versus 6.6%, p=0.011). Subgroup analyses revealed that patients of scleral tunnel incision who continued taking aspirin had a higher incidence of subconjunctival hemorrhage compared with those who discontinued (25.5% versus 10.9%, p=0.038), but no same conclusion in clear corneal incision cases (8.8% versus 5.0%, p=0.483). …”
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Relationship between systemic immune-inflammation index and depression among individuals with and without cardiovascular disease by Dan Liu, Chaojie He, Xinguo Luo

“…We also performed sensitivity analyses and subgroup analysis. Results The total prevalence of depressive symptoms was 8.73% among the 29,479 participants analyzed. …”
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Relationship of METS-IR with cardiometabolic multimorbidity in China: a nationwide longitudinal cohort study by Chunyan Zhou, Yanyu Zhang, Xiaoyi Liu, Chenyu He, Shiyang Li, Shiyang Li

“…We used multiple cox proportional hazards regression and restricted cubic splines (RCS) analysis to evaluate the association between METS-IR and CMM. Subgroup analyses and interaction tests were also performed.ResultsDuring a median 109 (108–109) months of follow-up, 745 (10.7%) participants were diagnosed with new-onset CMM. …”
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The Effect of Autologous Dendritic Cell Immunotherapy on Kidney Function and Endothelial Dysfunction of Patients with Diabetic Kidney Disease (DKD): An Open Label Clinical Trial by Martina Lily Yana, Enda Cindylosa Sitepu, Jonny, Linda Chiuman, I Nyoman Ehrich Lister, Terawan Agus Putranto

“…Although there were no significant changes in ICAM, VCAM, and VEGF, subgroup analysis revealed a decrease in VCAM in macroalbuminuria patients and an increase in those with good glycemic control, suggesting differing endothelial responses. …”
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The predictive role of tertiary lymphoid structures in the prognosis and response to immunotherapy of lung cancer patients: a systematic review and meta-analysis by Xin Liu, Wu Lv, Danxue Huang, Hongxia Cui

“…Interestingly, in the Asia subgroup, the association between TLS and survival was especially significant, whereas there was no significant difference in Europe. …”
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Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease by Luiz Felipe Vasconcellos, João Santos Pereira, Marcelo Adachi, Denise Greca, Manuela Cruz, Ana Lara Malak, Helenice Charchat-Fichman, Mariana Spitz

“…The MTA scale correlated with Stroop test and Fazekas scale with figure memory test, digit span, and Stroop test according to the subgroup evaluated. Visual scales by MRI in MCI should be evaluated by cognitive domain and might be more useful in more severely impaired MCI or dementia patients.…”
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Polymorphism in the Vesicular Monoamine Transporter 2 Gene Decreases the Risk of Parkinson’s Disease in Han Chinese Men by Xinglong Yang, Pingrong Xu, Quanzhen Zhao, Ran An, Hua Jia, Zhuolin Liu, Yanming Xu

“…None of the observed haplotypes showed a significant association with PD. Subgroup analysis by gender and age at onset revealed a significant association between the A allele of rs363371 and PD in Han Chinese males relative to healthy controls (OR 0.799, 95%  CI 0.665 to 0.959, P=0.016), and this association remained significant after adjusting for age (OR 0.785, 95%  CI 0.652 to 0.945, P=0.011). …”
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Association between right atrial area measured by echocardiography and prognosis among pulmonary arterial hypertension: a systematic review and meta-analysis by Ke Liu, Chunhua Zhang, Bingyu Chen, Mingfeng Li, Peican Zhang

“…Similarly, the risk of the composite endpoint also significantly increased by 53% for every 5-unit increase in RAA/RAAI (HR 1.53, 95% CI 1.23 to 1.89, p<0.001). Subgroup analyses in which the patients were stratified by RAA and RAAI were consistent with the main results.Conclusion The meta-analysis suggested that enlarged RAA/RAAI were associated with increased risk of poor prognosis in patients with PAH.…”
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Global, regional, and national burdens: An overlapping meta-analysis on Staphylococcus aureus and its drug-resistant strains by Shuaibu Suleiman Adeiza, Md. Aminul Islam, Aminu Shittu

“…Data analysis included parsing of study-level statistical power, assessment of primary study overlap, pooling of meta-analysis results, subgroup and temporal analysis. Results: Totally 41 studies (64 meta-analyses) were selected by the inclusion criteria. …”
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Association between metabolic dysfunction associated steatotic liver disease and gallstones in the US population using propensity score matching by Yingying Zhang, Jingjing Zhang, Dan Yu, Fan Tu, Jun Liu, Bing Han, Binghua Li, Yihang Yuan, Chaobo Chen, Mingli Zhou

“…This association remained robust across crude and adjusted analyses, with subgroup and sensitivity analyses further supporting the findings. …”
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The effect of healthy eating index-2015 in the associations of biological aging and non-alcoholic fatty liver disease: an interaction and mediation analysis by Xiang Zhang, Zhijie Ding, Yong Yan, Weiming Yang, Xiaoming Ai, Yongping Zhou

“…Weighted multivariable logistic regression analysis, restricted cubic spline (RCS), and subgroup analysis were performed to analyze the association of BA and HEI-2015 with prevalence of NAFLD and the mediation effect of HEI-2015 was also discussed. …”
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Association between sleep patterns and depression in older adults: a cross-sectional study using data from the National Health and Nutrition Examination Survey 2007–2014 by Yi Niu, Yuqin Sun, Yijie Xie, Shun Yu

“…Logistic multiple linear regression was used to assess the association of sleep factors and sleep patterns with the risk of depressive symptoms.Conduct subgroup analyses to ensure robustness of findings. …”
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Use and impact of social prescribing: a mixed-methods feasibility study protocol by Uy Hoang, Harshana Liyanage, Simon de Lusignan, Victoria Tzortziou Brown, Filipa Ferreira, Ivelina Yonova, Lucy Moore, Anant Jani

“…Introduction Social prescribing aims to address social determinants of health, which account for 80%–90% of health outcomes, but the evidence base behind it is limited due to a lack of data linkingsocial prescribing activity and outcomes.Methods and analysis The objective of the quantitative component of this feasibility studyisto identify the characteristics of individuals who receive social prescriptions and describe the use and estimate the impact of social prescribing; the latter will be done on a homeless subgroup. We will use the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) primary care sentinel network, whose general practicescover a population of over 4 000 000 patients. …”
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Sulfur Hexafluoride (SF6) versus Perfluoropropane (C3F8) in the Intraoperative Management of Macular Holes: A Systematic Review and Meta-Analysis by Idan Hecht, Michael Mimouni, Eytan Z. Blumenthal, Yoreh Barak

“…Similar rates of closure between SF6 and C3F8 were reported in eight out of nine studies, regardless of subgroup analyses. All studies reporting visual outcomes showed similar results when comparing SF6 to C3F8 at one to six months of follow-up. …”
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Efficacy and Safety of New Oral Anticoagulants versus Warfarin in the Resolution of Atrial Fibrillation with Left Atrial/Left Atrial Appendage Thrombus: A Systematic Review and Met... by Guan-lian Mo, Jing Wen, Yu-yu Ye, Yong-qi Lu, Tian-ming Gan, Ying-jie Yang, Jin-yi Li

“…Meta-analysis showed that NOACs had a significantly higher thrombolysis rate than VKAs (78.0% vs. 63.5%, odds ratio (OR) = 2.32, 95% confidence interval (CI) 1.71 to 3.15, p < 0.0001). Subgroup analysis revealed rivaroxaban to be more effective than VKAs, whereas there was no significant difference between dabigatran and apixaban. …”
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Emotional impact on healthcare providers involved in medical assistance in dying (MAiD): a systematic review and qualitative meta-synthesis by Alexander Simpson, Alireza Bagheri, Saumil Yogendra Dholakia

“…English language literature restriction and absence of subgroup analyses limit the generalisability of results.…”
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Comparative efficacy and safety of neoadjuvant radiotherapy for patients with borderline resectable, and locally advanced pancreatic ductal adenocarcinoma: a systematic review and... by Xin Wang, Dan Cao, Qingfeng Wang, Qiancheng Hu, Wanrui Lv

“…The quality of evidence will be evaluated using the version of Cochrane tool and Grades of Recommendation, Assessment, Development and Evaluation. Subgroup analysis and sensitivity analysis will be conducted in the present NMA.Ethics and dissemination This study will synthesise the evidence regarding dose schedule of neoadjuvant radiotherapy in patients with BRPC and LAPC. …”
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