Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation by Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang

“…Finally, we further demonstrated the results by RT-qPCR analysis, CCK-8 assay, wound healing assay, Transwell assay, etc.ResultsThrough the analysis of single-cell sequencing data in OS, we identified a highly specific subgroup, C2MKI67+ Osteoclast. The key signaling pathway APP and the top 1 transcription factor PPARG in this subgroup played essential roles in osteoclast proliferation and differentiation. …”
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Investigation of malaria vectors Anopheles in non-endemic areas of Thailand: in proximity to workplaces housing foreign migrant workers by Nurhadi Eko Firmansyah, Thaksaporn Thongseesuksai, Thidarut Boonmars, Porntip Laummaunwai

“…The remaining Anopheles mosquitoes are in the subgroup Cellia, comprised 437 (64.4%) Anopheles vagus, 39 (5.7%) Anopheles subpictus, and 2 (0.3%) Anopheles annularis. …”
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High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014) by Pingchuan Liu, Yuding Luo, Xing He, Jiali Zhang, Fanzhou Ren, Bingyang Zhang, Bo Zheng, Jian Wang

“…The RCS analysis found that the nonlinear association between BRI and unhealthy sleep patterns was not significant. Subgroup and sensitivity analyses indicated a consistently positive association between high BRI and unhealthy sleep patterns across most subgroups. …”
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Relationship between serum insulin-like growth factor 1 levels and ischaemic stroke: a systematic review and meta-analysis by Jinhui Li, Simiao Chen, Lan He, Yangni Li, Weinan Yang, Yishu Zhang, Lincheng Zhang, Yuyan Zhang

“…Review Manager V.5.2 was used to pool data and calculate the mean difference (MD) and its 95% CI. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were also performed in this meta-analysis.Results A total of 2277 patients were included in 17 studies. …”
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Smartphone applications for physical activity and sedentary behaviour change in people with cardiovascular disease: A systematic review and meta-analysis. by Kacie Patterson, Rachel Davey, Richard Keegan, Nicole Freene

“…Random effects model was used and the pooled mean difference between post scores were calculated. Subgroup analyses were conducted to examine differences based on diagnosis, sample size, age, intervention duration, activity tracker use, target behaviour, and self-report versus device-measured outcome.…”
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy by Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein

“…Hypothesis Cerebrospinal fluid‐specific OCBs are found in a subgroup of dogs with ASM‐resistant IE. Animals Eighty‐four dogs with IE were recruited from 3 referral centers and classified based on their response to ASM treatment (responsive, n = 56; resistant, n = 28). …”
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Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes by Rikke Andersen, Troels Holz Borch, Eva Ellebaek, Inge Marie Svane, Helle Westergren Hendel, Kasper Madsen

“…Nevertheless, progression is observed in a substantial subgroup of patients following an initial objective response to treatment with TILs. …”
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Long-term outcome and risk factors of reintervention after high intensity focused ultrasound ablation for uterine fibroids: a systematic review and meta-analysis by Yuya Dou, Lian Zhang, Yu Liu, Min He, Yanzhou Wang, Zhibiao Wang

“…A meta-analysis was applied to synthesize the reintervention rates for fibroids across various follow-up durations. Subgroup-analysis was conducted based on the year of surgery, sample size, guide methods, and non-perfusion volume ratio (NPVR). …”
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Early antibiotics administration reduces mortality in sepsis patients in tertiary care hospital by Suramath Isaranuwatchai, Jirawat Buppanharun, Thamonwan Thongbun, Kaewklao Thavornwattana, Monprach Harnphadungkit, Taweegrit Siripongboonsitti

“…However, subgroup analysis for the mortality rate at 90 days were not statistically significant. …”
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Association between body esteem and sugar-sweetened beverage intake among Chinese undergraduate students: a cross-sectional study by Jiawen Zhu, Yuanyuan Zhu, Zihe Zhao, Qianling Huang, Changju Liu, Zhi Zeng

“…Additionally, restricted cubic splines and subgroup analyses were implemented to further explore the associations.ResultsA total of 969 participants were included in the study, with 771 females (79.6%). …”
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Oxidative stress and retinopathy: evidence from epidemiological studies by Xiangliang Liu, Yu Chang, Yuguang Li, Yingrui Liu, Wei Song, Jin Lu, Naifei Chen, Jiuwei Cui

“…Restricted cubic spline (RCS) analysis explored the dose-response relationship between OBS and retinopathy. Subgroup analyses and interaction tests were conducted based on age, sex, race, BMI, education level, and diabetes status. …”
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Association between polycyclic aromatic hydrocarbons exposure and current asthma: a population-based study by Zhou Jin, Wen Sun, Guangfa Wang

“…In the fully adjusted model, log 3-Hydroxyfluorene, log 2-Hydroxyfluorene, and log 1-Hydroxypyrene remained significantly associated with current asthma. Subgroup analyses stratified by smoking status, gender, age, and body mass index (BMI) showed consistent associations between PAHs and current asthma, with some subgroups displaying stronger positive correlations. …”
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Exploring the significance of medical humanities in shaping internship performance: insights from curriculum categories by Chao Ting Chen, Anna Y.Q. Huang, Po-Hsun Hou, Ji-Yang Lin, His-Han Chen, Shiau-Shian Huang, Stephen J. H. Yang

“…Performance in basic sciences, clinical skills, MH, and internship rotations were investigated, including the subgroup analysis of MH curricula. Ten-fold cross-validation machine learning models (support vector machines, logistic regression, random forest) were performed to predict the internship grades. …”
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Swiss Orthopaedics Minimal Dataset: First Pilot Report of Reliability and Validity by Thorsten Jentzsch, Claudio Dora, Urs Müller, Mazda Farshad

“…The return rates of the SOMD were improvable (43% in 2016 and 31% in 2017). The subgroup of the test study population (n = 302) displayed a borderline acceptable criterion validity (correlation of the item of pain between SOMD and WOMAC hip: rho = 0.62, p<0.001). …”
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Beta-hydroxy-beta-methyl butyrate supplementation in critically ill patients: a systematic review and meta-analysis of randomized controlled trials by Yu Ren, Ya-Bei Gao, Da-Xing Yu, Hui-Bin Huang

“…To explore potential heterogeneity, we assessed study quality and performed subgroup analysis, sensitivity analysis, and quality of evidence.ResultsNine randomized controlled trials were included. …”
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The curvilinear relationship between Framingham Steatosis Index and depression: insights from a nationwide study by Chunqi Jiang, Bo Wang, Ning Wang, Jun Wang, Yinuo Qu, Guang Zhao, Xin Zhang, Xin Zhang

“…A recursive method was employed to identify inflection points. Subgroup analyses were conducted to examine differences in the association between FSI and depression within subgroups.ResultsOur research encompassed a total of 19,697 participants. …”
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Non-Completely Displaced Traumatic Rib Fractures: Potentially Less Crucial for Pulmonary Adverse Outcomes, Regardless of Classification by Hongrye Kim, Su Young Yoon, Jonghee Han, Junepill Seok, Wu Seong Kang

“…After excluding 280 patients with completely displaced RFX, we conducted a subgroup analysis with the remaining 341 patients. …”
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Association of pan-immune inflammation value and lung health in adults by Ya Lin, Xiao Lin, Chufan Ren, Lanlan Song, Chao Gu

“…The study incorporated subgroup analysis and interaction tests to examine associations within specific subpopulations. …”
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Association between transarterial chemoembolization refractoriness and prognosis in Chinese patients with hepatocellular carcinoma: a large retrospective cohort study by Qinxue Sun, Ziliang Wu, Xi Yin, Feng Li, Ri Liu

“…Furthermore, multivariate analysis identified TACE refractoriness as a significant predictor of poorer OS, yielding an adjusted hazard ratio (HR) of 5.96 (95% CI: 3.39-10.5, P &lt; 0.001). Subgroup analysis further demonstrated the robustness of these findings across subgroups, except in female patients (HR = 3.0, 95% CI: 0.72–12.52; P=0.131).ConclusionsCCI-defined TACE refractoriness is associated with reduced OS in patients with BCLC stage B HCC undergoing TACE.…”
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Relationship between triglyceride levels and different snoring states: a systematic review and meta-analysis by Fei-Fei Hou, Bei-Bei Wang, Ye Chen, Qiong Wang, Qiong Wu, Li-Na Yan

“…Moreover, we performed subgroup analysis according to snoring status and body mass index (BMI). …”
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