Indicators of free radical oxidation in neutrophils of patients with primary and recurrent soft tissue sarcomas by I. A. Goroshinskaya, I. V. Kaplieva, E. M. Frantsiyants, L. N. Vashchenko, T. O. Lapteva, T. V. Ausheva, L. A. Nemashkalova, P. S. Kachesova, Yu. Yu. Kozel

“…The comparison groups (donors) consisted of 12 men and 17 women divided into the same age subgroups: ≤ 45 years and > 45 years.Results. In donors, there was a multiple decrease in the SOD/TPA ratio with age, especially in women, and in men this was accompanied by an age-related decrease in GPx activity. …”
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The effect of anterior disc displacement with polycystic ovarian syndrome on adolescent condylar bone remodeling by Jiali Sun, Chuyao Wang, Jieyun Zhao, Xin Nie, Chuan Lu, Xiang Ye, Dongmei He

“…Each group was divided into 2 subgroups according to ADD observation (A1, B1, C1) and DR (A2, B2, C2). …”
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Effects of exercise dose based on the ACSM recommendations on depression in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials by Yang Fang, Yang Fang, Bai Xiaoling, Li Huan, Li Huan, Guan Yaping, Zhang Binying, Wang Man, Wu Juan, Liu Xinyu

“…No notable disparities were noted in the effects of exercise duration or patient age on depression outcomes between the subgroups (p = 0.86, p = 0.48).ConclusionExercise interventions that exhibit high adherence to the ACSM guidelines prove to be more efficacious in alleviating depression among hemodialysis patients as compared to those with low or uncertain adherence levels.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/#myprospero…”
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The incidence of outpatient care within 24 months from SARS-CoV-2 infection in the general population: a multicenter population-based cohort study by Federico Banchelli, Carlo Gagliotti, Angela De Paoli, Rossella Buttazzi, Elena Narne, Enrico Ricchizzi, Silvia Pierobon, Ugo Fedeli, Gisella Pitter, Elisa Fabbri, Michele Tonon, Elisa Gentilotti, Maurizia Rolli, Evelina Tacconelli, Maria Luisa Moro, Francesca Russo, Elena Berti

“…The increased demand for resources can last up to two years after infection in particular subgroups of patients such as subjects admitted to hospital during the acute phase due to the severe presentation of the disease.…”
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A novel gene signature for predicting outcome in colorectal cancer patients based on tumor cell-endothelial cell interaction via single-cell sequencing and machine learning by Lina Pang, Qingxia Sun, Wenyue Wang, Mingjie Song, Ying Wu, Xin Shi, Xiaonan Shi

“…Results: Our analysis revealed two distinct cell subgroups, Malignant Cluster01 tumor cells, and Tip-like endothelial cells, showing significant interaction and closely associated with colorectal cancer prognosis. …”
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Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infe... by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…Based on whether patients had chronic HBV, iCCA was divided into two subgroups: HBV-positive (n = 50 patients, including 9 with cirrhosis) vs. …”
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Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease by Guoqing Zhang, Hongyan Luo, Xiaohua Lu, Yonghua Liu, Mei Wang, Bo Li, Haixia Lu, Yali Zheng

“…Also, we mapped the ROC curves.Meanwhile, in order to determine the underlying mechanism and relevant biological features of CKD, we conducted differential analysis between high and low risk subgroups in CKD. Moreover,we employed ssGSEA algorithm to evaluate the infiltration abundance of immune cells and calculated the correlation among the immune cells with the key genes. …”
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Postoperative mortality in New Zealand following general anaesthetic: demographic patterns and temporal trends by James Stanley, Sarah Jackson, Jason K Gurney, Melissa McLeod, Doug Campbell, Luke Boyle, Elizabeth Dennett, Jonathan Koea, Dick Ongley, Diana Sarfati

“…Objectives In this manuscript, we describe broad trends in postoperative mortality in New Zealand (a country with universal healthcare) for acute and elective/waiting list procedures conducted between 2005 and 2017.Design, participants and setting We use high-quality national-level hospitalisation data to compare the risk of postoperative mortality between demographic subgroups after adjusting for key patient-level confounders and mediators. …”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

“…Serum samples will be taken before and 28 days after the booster, with additional sampling for exploratory endpoints in subgroups. Adverse events are solicited for the first three days following vaccination and recorded throughout the study period. …”
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Predictive models for the implementation of targeted reproductive management in multiparous cows on automatic milking systems by Fergus P. Hannon, Martin J. Green, Luke O'Grady, Chris Hudson, Anneke Gouw, Laura V. Randall

“…Though the performance described is comparable with previously reported models, their utility for the implementation of TRM is limited by poor classification accuracy within key subgroups. Of note within this study is the failure of the addition of auxiliary data sources to increase the accuracy of prediction over models built using AMS data alone. …”
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The impact of biological and psychosocial factors on the formation of mental disorders in patients who have experienced COVID-19 and exposed to the stressors of the SARS-COV-2 pand... by N.O. Maruta, V.Y. Fedchenko, I.O. Yavdak, T.V. Panko

“…The obtained data of a comprehensive study made it possible to distinguish among patients with first diagnosed mental disorders 3 subgroups with characteristic differences in the course and conditions of treatment of the experienced coronavirus disease COVID-19, the structure and significance of the stressors of the SARS-COV-2 pandemic, which the patients encountered, initial psychopathological manifestations. …”
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Fetal growth and risk of stillbirth: a population-based case-control study. by Radek Bukowski, Nellie I Hansen, Marian Willinger, Uma M Reddy, Corette B Parker, Halit Pinar, Robert M Silver, Donald J Dudley, Barbara J Stoll, George R Saade, Matthew A Koch, Carol J Rowland Hogue, Michael W Varner, Deborah L Conway, Donald Coustan, Robert L Goldenberg, Eunice Kennedy Shriver National Institute of Child Health and Human Development Stillbirth Collaborative Research Network

“…Data were weighted to account for the sampling design and differential participation rates in various subgroups. Among 527 singleton stillbirths and 1,821 singleton live births studied, stillbirth was associated with SGA based on population, ultrasound, and individualized norms (odds ratio [OR] [95% CI]: 3.0 [2.2 to 4.0]; 4.7 [3.7 to 5.9]; 4.6 [3.6 to 5.9], respectively). …”
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Domestic violence victimisation and its association with mental distress: a cross-sectional study of the Yangon Region, Myanmar by Johanne Sundby, Espen Bjertness, Lars Lien, Win Thuzar Aye, Hein Stigum, Berit Schei

“…Objectives To estimate the prevalence of domestic violence, with subgroups of physical, sexual and emotional violence, among men and women and to assess the association between any lifetime domestic violence (DV) and mental distress among ever-married men and women.Design We conducted a cross-sectional study from October to November 2016 using a multistage sampling design. …”
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Just-In-Time Adaptive Interventions to Promote Behavioral Health: Protocol for a Systematic Review by Lauren M Henry, Morkeh Blay-Tofey, Clara E Haeffner, Cassandra N Raymond, Elizabeth Tandilashvili, Nancy Terry, Miryam Kiderman, Olivia Metcalf, Melissa A Brotman, Silvia Lopez-Guzman

“…We will conduct meta-analyses for the distal and proximal outcomes conditional upon sufficient homogeneity in subgroups. Moderation (conditional upon sufficient heterogeneity of outcomes) and mediation (ie, whether changes in proximal outcomes mediate the relation between JITAIs and distal outcomes) will be conducted as appropriate. …”
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Effects of High‐Fructose Corn Syrup Addition to Broiler Diets on Performance, Carcass Yield, Visceral Weights, Gut pH and Some Blood Parameters by Gökhan Şen, Mehmet Demirci, Şevket Evci, Ali Şenol, Mehmet Akif Karsli

“…Methods A total of 120 Ross 308 chicks at the age of 0 day were divided into three main groups with four subgroups each. The groups consisted of a control (CON), low‐HFCS and high‐HFCS groups. …”
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Evaluation of indirect indices in the insulin resistance assessment in patients with different body mass index by Lejla Čano Dedić, Arzija Pašalić, Emsel Papić, Emir Begagić, Sabina Šečić Selimović, Mario Gazibarić, Sabina Šegalo

“…Results: Significant differences between the subgroups were found in the mean values for HOMA-IR, TyG, TyG-BMI, and METS- IR, while the control group had the highest mean values for the indirect indices QUICKI and MCAi (p < 0.001). …”
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The Validation of a Novel, Sex-Specific LDL-Cholesterol Equation and the Friedewald, Sampson-NIH, and Extended-Martin–Hopkins Equations Against Direct Measurement in Korean Adults... by Hyun Suk Yang, Soo-Nyung Kim, Seungho Lee, Mina Hur

“…The validation metrics included Bland–Altman analysis for mean absolute percentage error (MAPE) and agreement of the categorization based on the NCEP ATP-III guidelines, assessed by sex and lipid subgroups. <b>Results:</b> The derived SSLE equation was as follows: for TG < 200 mg/dL, LDLc = 0.963 × TC − 0.881 × HDLc − 0.111 × TG + 0.982 × Sex − 6.958; for TG ≥ 200 mg/dL, LDLc = 0.884 × TC − 0.646 × HDLc − 0.126 × TG + 3.742 × Sex − 3.214 (male = 1, female = 0). …”
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Use of Imaging Modalities in Real Life: Impact on Visual Acuity Outcomes of Ranibizumab Treatment for Neovascular Age-Related Macular Degeneration in Germany by Joachim Wachtlin, Georg Spital, Steffen Schmitz-Valckenberg, Sandra Liakopoulos, Jessica Vögeler, Bettina Müller, Focke Ziemssen, Ocean study group

“…Over the remaining study course, this combination was used infrequently (range: 7.6% to 13.4%) and continually decreased over time; most patients received only OCT examinations (range: 48.9% to 52.5%; median: 3 within 12 months and 4 within 24 months). Subgroups according to the number of OCT examinations (≤4, rarely OCT examined; 5–8, moderately OCT examined; ≥8, well monitored) were associated with different treatment frequencies and outcomes: Rarely OCT-examined patients had received a median of 4 injections (range: 1–19) at 24 months; well-monitored patients had received a median of 8 injections (range: 1–21) at 24 months. …”
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Cardiovascular health in breast cancer patients: insight on BRCA1/2 mutations impact by Panagiotis Mallios, Mehdi Dehghan Manshadi, Laila Hubbert, Tajeri Aydin, Claudia Maes, Johanna Rantala, Annelie Liljegren, Narsis A. Kiani, Elham Hedayati

“…Analyses focused on single and multiple CVD events, comparing inpatient and outpatient settings across subgroups. Results The cohort included 438 BRCA-BC and 32,626 Sporadic-BC patients. …”
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Incidence Rate of Type 2 Diabetes Mellitus after Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of 170,139 Women by Zhuyu Li, Yunjiu Cheng, Dongyu Wang, Haitian Chen, Hanqing Chen, Wai-kit Ming, Zilian Wang

“…Data from selected studies were extracted, and meta-analysis was performed using the random-effects model. Subgroups analyses were based on the sample size of gestational diabetes, geographic region, maternal age, body-mass index, diagnostic criteria, and duration of follow-up. …”
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