Disparities in time to treatment initiation of invasive lung cancer among Black and White patients in Tennessee. by Lohuwa Mamudu, Saanie Sulley, Paul H Atandoh, Joanne L Reyes, Raquibul A K M Bashar, Martin Whiteside, Archana J McEligot, Hadii M Mamudu, Faustine Williams

“…Black patients aged <45 years (adjusted hazard ratio [aHR] = 1.40; 95% confidence interval [CI] = 1.01-1.94) and married White patients (aHR = 1.13; 95% CI = 1.07-1.18) had the highest increased risk of late treatment among their respective racial subgroups. In the general sample, patients with private health insurance had (aHR = 1.08; 95% CI = 1.01-1.16) higher risk of late treatment beyond 2.7 weeks compared to self-pay/uninsured patients. …”
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Nonalcoholic Fatty Liver Disease as a Potential Risk Factor for Cardiovascular Disease in Patients with Type 2 Diabetes: A Prospective Cohort Study by Mohammad Dehghani Firouzabadi, Amirhossein Poopak, Ali Sheikhy, Fatemeh Dehghani Firouzabadi, Fatemeh Moosaie, Soghra Rabizadeh, Sara Momtazmanesh, Manouchehr Nakhjavani, Alireza Esteghamati

“…Cox regression analysis was used to assess the association between NAFLD, liver enzyme level, aspartate aminotransferase to platelet ratio index (APRI), and the incidence risk of CVD and its subgroups (i.e., myocardial infarction, chronic heart disease, coronary artery bypass grafting, and percutaneous coronary intervention). …”
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Infective agents and polymyalgia rheumatica: key discussion points emerging from a narrative review of published literature by Ciro Manzo, Marco Isetta, Alberto Castagna

“…Secondly, we compared data of PMR-only patients with PMR and overlapping GCA to seek any commonalities or differences regarding the type of infectious agent in these two subgroups. Material and Methods We performed a non-systematic literature search on Embase and Medline (COVID interface) with the following search terms: “polymyalgia rheumatica” AND “infections” OR “infectious agents”, both MESH headings and free-text (in each language they were written). …”
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A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies by Reza Panahizadeh, Padideh Panahi, Vahid Asghariazar, Shima Makaremi, Ghasem Noorkhajavi, Elham Safarzadeh

“…ICIs like pembrolizumab and nivolumab have shown significant survival benefits in specific GC subgroups. Cancer vaccines and CAR-T cell therapies demonstrate potential, while mAbs targeting HER2 and VEGFR pathways enhance outcomes in combination regimens. …”
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Genome wide identification of MATE and ALMT gene family in lentil (Lens culinaris Medikus) and expression profiling under Al stress condition by Ankita Tripathi, Dharmendra Singh, Jyotika Bhati, Deepti Singh, Jyoti Taunk, Jawaher Alkahtani, Abdulrahman Al-Hashimi, Madan Pal Singh

“…Method and results In this study, 90 MATE and 14 ALMT genes were identified and clustered into four (MATE) and five (ALMT) subfamilies/clades with smaller subgroups. All the MATE and ALMT genes were unevenly dispersed across lentil chromosomes. …”
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Centroid-AME: An open-source software for estimating avian migration trajectories using population centroids movement in the annual cycle by Shi Feng, Alice C. Hughes, Qinmin Yang, Leyi Li, Chao Li

“…We apply an unsupervised Mean-Shift clustering algorithm to extract dense clusters of observations and identify subgroups of the species population. The centroids are then grouped using a shortest path with the lowest cost and migration trajectories are estimated by fitting them respectively. …”
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The associations between dietary advanced glycation-end products intake and self-reported infertility in U.S. women: data from the NHANES 2013–2018 by Lingxia Tong, Xiaohui Zhang, Jingsi Chen, Huanying He, Wenzhuo Zhang, Zhongxiao Wan, Hong Zhang

“…Compared to the lowest tertile, total dietary AGEs (P-trend = 0.089) and CML (P-trend = 0.032) in the upper tertile were positively correlated with female infertility, and the corresponding odds radios (ORs) (95% confidence interval (CI)) were 1.44 (1.01, 2.06) and 1.64 (1.10, 2.45) respectively. Subgroups analysis found that in participants with overweight and obese, each 1-SD increment in dietary AGEs, CML and MG-H1 level was associated with 18% (95% CI: 1-38%), 21% (95% CI: 1-46%), and 16% (95% CI: 0-36%) elevated risk of infertility. …”
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Patients with Liver Cirrhosis as Frequent Attenders of Emergency Departments by Chen-Ju Chuang, Yi-Fang Wu, Kai-Hsiang Wu, Yi-Chuan Chen

“…Most studies regarding frequent attenders of EDs examine general patients without classifying certain subgroups. This study aimed to investigate patients with liver cirrhosis who present repeatedly to the ED. …”
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Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis by Nicola Bizzaro, Franco Franceschini, Maria Infantino, Carlo Selmi, Gian Domenico Sebastiani, Francesca Motta, Davide Giavarina, Boaz Palterer

“…The study of RF isotypes has further attempted to improve diagnostic accuracy and identify specific subgroups of patients. The main objective of this study is to provide an analysis of the literature on the role of RF isotypes in the diagnosis and prognosis of rheumatoid arthritis (RA).Methods We performed a systematic literature review and meta-analysis on the role of RF isotypes in RA (only in English, from PubMed, search terms: “rheumatoid factor isotypes”, “diagnosis”, “prognosis” and “rheumatoid arthritis”, last search 31 July 2022, two independent assessment of quality and biases, results included in tables and in the meta-analysis).Results Thirty-six articles were examined (7517 patients). …”
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Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder by He Y, He Y, Cheng B

“…This research aims to explore bacterial lipopolysaccharide (LPS)- and immune-related (BLI) molecular subgroups in ASD to enhance understanding of the disorder.Methods: We analyzed 89 control samples and 157 ASD samples from the GEO database, identifying BLI signatures using least absolute shrinkage and selection operator regression (LASSO) and logistic regression machine learning algorithms. …”
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PATIENTS' CHRONOTYPE INFLUENCE IN TREATMENT EFFICIENCY OF PLACENTA CRYERXTRACT CHANGES IN MAXILLOFACIAL PHLEGMONS by K. Lokes, M. Pérez Sayáns, V. Lychman, D. Steblovskyi, I. Boiko, D. Avetikov

“…These patients were divided into three clinical groups, each comprising 30 individuals, further categorized into two subgroups based on circadian rhythms. Analyzing the obtained data, it can be asserted that the most significant changes in markers of lipid peroxidation in patients with superficial phlegmons of maxillofacial localization were experienced in both experimental groups when used against the background of treatment according to standard protocols of intravenous injections of the cryopreserved placenta without and in combination with local injection of the cryopreserved placenta as part of "Levomekol" ointment, in contrast to the control group. …”
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Curvilinear association between Framingham Steatosis Index and chronic kidney disease: a nationwide cross-sectional study by Chunqi Jiang, Bo Wang, Jun Wang, Yinuo Qu, Xin Zhang, Xin Zhang

“…In the stratified curve analysis, the results were essentially consistent with the overall findings, except for the subgroups with BMI &gt; 30 and age &gt; 50.ConclusionWe found a curvilinear relationship between FSI and CKD.…”
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Predictors of frequency of CF care in the US Cystic Fibrosis Foundation Patient Registry. by Alexandra C Hinton, Edmund H Sears, Jonathan B Zuckerman, Sara Lopez-Pintado

“…Comprehensive analysis of patient-level predictors of visit frequency is needed to optimize protocols for stable pwCF and identify subgroups at high risk of gaps and poor outcomes, promoting equitable treatment for all pwCF.…”
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Higher Life’s Crucial 9 protects against infertility among U.S. women aged 18–45 years by Shaoqun Huang, Shuqin Duan, Seok Choi, Hongyang Gong

“…Interaction analyses were conducted on subgroups to validate the findings.ResultsThere was a significant negative association between LC9 and infertility. …”
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Policies, programmes and research on adolescent and youth sexual and reproductive health in South Sudan: a systematic scoping review by Neha S Singh, Jessica Crawford, Chirrilo Madut, Chol Bak, Zack Wol

“…Vulnerable populations were excluded from research, policies and programmes, including very young adolescents, LGBTQ youth and youth with disabilities.Conclusions Quality research has been done on AYSRH in South Sudan; however, there are many key areas that have not been addressed such as maternal mortality and morbidities, safe abortion and tailored interventions for specific subgroups. While some policies and programmes were identified that address AYSRH, robust programme evaluation processes or evidence of follow-through or implementation of government strategies are lacking.…”
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Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors-γ2 with Type 2 Diabetes Mellitus and Its Interaction with... by Habiba Al-Safar, Ahmed Hassoun, Shaikha Almazrouei, Wala Kamal, Bachar Afandi, Naushad Rais

“…Genotyping for rs10885409 (TCF7L2) and rs1801282 (PPAR-γ2 P12A) variants was accomplished with a TaqMan assay. The subgroups were constituted according to obesity status. …”
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Association of Red Blood Cell Distribution Width With Carotid–Femoral Pulse Wave Velocity in a Southern Chinese Population by Xing Yu, Yali Huang, Yunyun Su, Liangdi Xie

“…Participants were stratified into four subgroups based on RDW quartiles: Q1 (RDW ≤ 12.80%), Q2 (12.80% < RDW ≤ 13.40%), Q3 (13.40% < RDW ≤ 14.10%), and Q4 (RDW > 14.10%). …”
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Assessment of Zinc Alpha-2 Glycoprotein Level in Gestational Diabetes Woman in Respect to Glycemic Status with and without Treatment by Bara Nahdh Saleem, Manal Khalid Abdulridha, Hind Abdalkhaliq Showman, Manal Sabbar

“…Significant variation in ZAG levels was observed among subgroups of treated GDM pregnant women (p<0.01). The metformin group exhibited the lowest level of ZAG. …”
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Access to Diagnostics and Treatment for People With Metastatic EGFR-Positive NSCLC: Lessons From Project PRIORITY by Jill Feldman, MA, Ivy Elkins, MBA, Zofia Piotrowska, MD, Bellinda L. King-Kallimanis, PhD, Tendai Chihuri, MD, Carly Johnson, BS, Alecia Clary, PhD, Teri Kennedy, MA, Upal Basu Roy, PhD, MPH

“…Descriptive statistics were used and included subgroups based on residency and cancer stage. Results: Of the 425 participants, most were female (67%), under 60 years old (53%), and resided in the United States (74%). …”
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Cost-Effectiveness of the Prenatal Detection of Congenital Heart Diseases: A Systematic Literature Review by Darío Londoño Trujillo, Paula A. Castro García, Kristian K. Rojas López, Karen J. Moreno-Medina, María T. Dominguez Torres, Rodolfo J. Dennis Verano, Nestor F. Sandoval Reyes

“…**Discussion:** While recent cost-effectiveness analyses demonstrated improved methodological quality, there was a lack of homogeneity due to differences in comparators and population subgroups analyzed. Despite this heterogeneity, fetal ultrasonography screening was consistently identified as a cost-effective strategy, with its cost-effectiveness heavily influenced by the expertise of the interpreting physician. …”
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