Exploring public support for novel tobacco and alcohol control policies in Great Britain 2021–2023: A population-based cross-sectional survey by Vera Helen Buss, Lion Shahab, Sharon Cox, Loren Kock, Melissa Oldham, Linda Bauld, Hazel Cheeseman, Garth Reid, Jamie Brown

“…This trend was apparent across all sociodemographic subgroups. With one exception, the policies included in this study were supported by more than half of the participants. …”
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Tackling ALT-positive neuroblastoma: is it time to redefine risk classification systems? A systematic review with IPD meta-analysis by Marta Avinent-Pérez, Frank Westermann, Samuel Navarro, Amparo López-Carrasco, Rosa Noguera

“…Patients were stratified into ALT-positive and TMM-negative subgroups. Overall and event-free survival probabilities were evaluated. …”
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Case report: 10-year follow-up of a patient with neuronal intranuclear inclusion disease and a literature review by Kenji Yoshida, Tomotsugu Kaga, Sachiko Hosoyama, Jun-ichi Niwa, Jun Sone, Naoki Mabuchi

“…In the literature review, we analyzed patients with NIID by classifying them into subgroups and found that high signals on fluid-attenuated inversion recovery (FLAIR) and DWI were related to dementia. …”
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Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancer by Wen Yin, Yanting Ao, Qian Jia, Chao Zhang, Liping Yuan, Sha Liu, Wanmeng Xiao, Gang Luo, Xiaomin Shi, Chen Xin, Maolin Chen, Muhan Lü, Zehui Yu

“…We identified two molecular subtypes and three genetic subtypes, two risk subgroups according to median risk values, constructed a prognostic model including thirteen genes (TIMP1, GDF15, UCN, KRT4, POU4F1, NXPH1, SIX2, NPC1L1, KLK12, IGFL1, FOXD1, ASPG, and CYP4F8), and validated the performance of each aspect of the model in an external database. …”
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Machine learning based identification of an amino acid metabolism related signature for predicting prognosis and immune microenvironment in pancreatic cancer by Xiaohong Liu, Xing Wang, Jie Ren, Yuan Fang, Minzhi Gu, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Jialu Bai, Decheng Jiang, Yuemeng Tang, Bo Ren, Lei You, Yupei Zhao

“…Subsequent GSEA was employed to unveil the enriched gene sets and signaling pathways within high- and low-risk subgroups. TMB and drug sensitivity analyses were carried out via Maftools and oncoPredict R packages. …”
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Long-term exposure to air pollution and lower respiratory infections in a large population-based adult cohort in Catalonia by Anna Alari, Otavio Ranzani, Carles Milà, Sergio Olmos, Xavier Basagaña, Payam Dadvand, Talita Duarte-Salles, Mark Nieuwenhuijsen, Cathryn Tonne

“…We assessed the influence of long-term air pollution exposure on hospital admission for lower respiratory infections and whether there are vulnerable subgroups. Methods: We used a populational cohort in Catalonia, Spain, comprising 3,817,820 adults residing in Catalonia as of January 1, 2015. …”
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Retrospective analysis of 300 microbial cell-free DNA sequencing results in routine blood stream infection diagnostics by Claudio Neidhöfer, Claudio Neidhöfer, Niklas Klein, Niklas Klein, Aylin Yürüktümen, Tessa Hattenhauer, Rebekka Mispelbaum, Christian Bode, Tobias A. W. Holderried, Achim Hoerauf, Marijo Parčina

“…Further, the specific patient subgroups that most benefit from this analysis must be worked out. …”
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Analysis of Inflammatory Mediator Profiles in Sepsis Patients Reveals That Extracellular Histones Are Strongly Elevated in Nonsurvivors by Tanja Eichhorn, Ingrid Linsberger, Lucia Lauková, Carla Tripisciano, Birgit Fendl, René Weiss, Franz König, Gerhard Valicek, Georg Miestinger, Christoph Hörmann, Viktoria Weber

“…Treatment strategies relying on a “one-fits-all” approach have failed to reduce mortality, suggesting that therapeutic targets differ between patient subgroups and highlighting the need for accurate analysis of the molecular cascades to assess the highly variable host response. …”
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Study protocol of the METAPANC trial - intensified treatment in patients with local operable but oligometastatic pancreatic cancer - multimodal surgical treatment versus chemothera... by Michael Ghadimi, Uwe Pelzer, Marc G. Besselink, Jens Siveke, Ralph Telgmann, Rickmer Braren, Hanneke Wilmink, Marie Crede, Alexander Koenig, Ute Koenig, Sven Thorsten Liffers, Kai Antweiler, Bas Uijterwijk, Hanna Seppanen, Arno Nordin, Pauli Puolakkainen, Olav F. Dajani, Knut Jørgen Labori, Mia Johansson, Svein Olav Bratlie, Tim Friede, Peter Jo

“…To identify patient subgroups that might benefit from multimodal surgical therapy, additional information on tumor genetics could supplement valid parameters. …”
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Vitamin D Supplementation and Hemoglobin Levels in Hypertensive Patients: A Randomized Controlled Trial by Jana B. Ernst, Andreas Tomaschitz, Martin R. Grübler, Martin Gaksch, Katharina Kienreich, Nicolas Verheyen, Winfried März, Stefan Pilz, Armin Zittermann

“…Likewise, vitamin D had no significant effect on Hb levels in the subgroups of anemic patients or in patients with initial 25OHD levels <30 nmol/L. …”
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Efficacy and safety of combined low‐dose rituximab regimen for chronic inflammatory demyelinating polyradiculoneuropathy by Ying Du, Qi Yan, Chuan Li, Wenping Zhu, Chao Zhao, Yunfeng Hao, Lin Li, Dan Yao, Xuan Zhou, Ying Li, Yuting Dang, Rong Zhang, Lin Han, Yuanyuan Wang, Tao Hou, Juan Li, Hailin Li, Panpan Jiang, Pei Wang, Fenying Chen, Tingge Zhu, Juntong Liu, Shuyu Liu, Lan Gao, Yingjun Zhao, Wei Zhang

“…Results Compared to conventional therapy cohort, combined rituximab cohort presented better improvements and higher proportion of favorable response in scales assessments at each visit, as well as significantly reduced corticosteroids dosage and deterioration occurrence during the follow‐up. Analyses of subgroups showed better improvements in both typical CIDP and CIDP variants in combined rituximab cohort than those in conventional therapy cohort, but had no differences between each other. …”
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Deconstructing the Monolith: An Educational Module for Understanding Disparities Within Asian American, Native Hawaiian, and Pacific Islander Populations by Karan D. Luthria, Dylan K. Kim, Samantha Xing, Mina Yuan, Jerry Zhou, Catherine A. Shu, Usha S. Krishnan

“…The 1-hour session involved a preworkshop evaluation; a PowerPoint presentation outlining the history of the Asian monolith bias, health disparities within AANHPI subgroups, and strategies for health care professionals and trainees to engage effectively with these communities; and a postworkshop evaluation. …”
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Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy by Michał Marchel, Agnieszka Madej-Pilarczyk, Agata Tymińska, Roman Steckiewicz, Janusz Kochanowski, Julia Wysińska, Ewa Ostrowska, Paweł Balsam, Marcin Grabowski, Grzegorz Opolski

“…The aim of the study was to characterize and compare the cardiac morphology and function in the two main genetic subgroups of EDMD with the use of echocardiography. …”
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Comprehensive analyses reveal the promising value of gasdermins as prognostic biomarkers and immunotherapeutic targets in head and neck squamous cell carcinoma by Huageng Huang, Jingjing Ge, Shunzhen Lu, Xinyi Deng, Ying Tian, He Huang, Zhao Wang, Yuyi Yao, Huangming Hong, Tongyu Lin

“…Additionally, the expression of GSDMs differed significantly between the clinicopathological subgroups of HNSC patients. Overall survival of HNSC patients benefited from increased GSDMC expression (HR = 0.67, P = 0.0053) and decreased GSDME expression (HR = 1.42, P = 0.0140). …”
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Association of extreme high temperature weather with non-accidental deaths among residents of Yichang city: a time-stratified case-crossover analysis by Xiaoyan MING, Yang HAN, Zhongcheng YANG, Zaoxia WANG, Shuguang XIE, Chuangang FAN

“…Stratified analysis showed that the effects of extreme high temperature events on non-accidental deaths persisted in different sex and age subgroups. For both male and female subgroups, the effect of P97.5-3 d was strongest at lag day 0, with ORs (95%CI) of 1.36 (1.21 – 1.54) for males and 1.24 (1.08 – 1.43) for females. …”
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Investigating the Efficacy of an Individualized Alpha/Delta Neurofeedback Protocol in the Treatment of Chronic Tinnitus by Dominik Güntensperger, Christian Thüring, Tobias Kleinjung, Patrick Neff, Martin Meyer

“…However, recent research also suggests that chronic tinnitus is a decidedly heterogeneous phenomenon, one that requires treatment of distinct subgroups or even on an individual level. Thus, the purpose of this study was to evaluate an individually adjusted alpha/delta neurofeedback protocol. …”
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Prevalence, risk and resilience factors of mental health conditions among female sex workers: a systematic review and meta-analysis by Olivia Kalinowski, Anastasiia Lotysh, Gizem Kaya, Franziska Kroehn-Liedtke, Lena Karoline Zerbe, Hristiana Mihaylova, Krisztina Sipos, Wulf Rössler, Meryam Schouler-Ocak

“…Future research should focus on under-researched regions and subgroups within this population to enhance understanding and support the development of comprehensive health services.Systematic review registrationPROSPERO, CRD42022312737, available from: https://www.crd.york.ac.uk/prospero/display_record.php?…”
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Impact of simulated gastric acid on the physical and mechanical properties of vacuum-formed retainers: an in vitro study by Huda M. Alkawari, Laila F. Baidas, Areen A. Alyahya, Renad A. Alotaibi, Eman I. Alshayea

“…Each specimen was immersed in distilled water, and then the specimens were divided into two subgroups: those with a pH of 4 and those with a pH of 1.2. …”
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The impact of Sudafed on spleen of albino mice by L. Alsaadi Yasmin, K. Abdul Ameer Bassam, Jasim Mohamad Ban, Kathum Omra Faiza

“…After the mentioned period, the mice of all subgroups were sacrificed and the spleens were removed, processed, sectioned and stained for histological analysis. …”
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Cost-effectiveness analysis of durvalumab with chemotherapy and maintenance durvalumab with or without olaparib for advanced endometrial cancer by Jiahao Zhang, Jianying Lei, Caicong You, Wu Fu, Bin Zheng, Hongfu Cai, Maobai Liu, Na Li

“…From a U.S. payer perspective, DOCT and DCT regimens are not cost-effective compared to CT for advanced or recurrent EC, including dMMR and pMMR subgroups, at a $150,000/QALY threshold.…”
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