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A comprehensive review of challenges and opportunities for stem cell research in India
Published 2025-01-01“…India is emerging as a prominent hub for the development of stem cell therapy (SCT), and it is important to assess the current state of stem cell research in India and the potential for advancement to promote stem cell-based therapy. …”
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82
Impacts of stem cells from different sources on wound healing rate in diabetic foot ulcers: a systematic review and meta-analysis
Published 2025-01-01“…These findings indicated that stem cell therapy might influence the progression of DFU.…”
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83
Understanding the multifaceted nature of peptide hydrogels in biomedical research
Published 2024-03-01“…In this review, we will present the recent advancements that have occurred in the field of peptide-based hydrogels concerning its biomedical applications especially delivery of targeted delivery, wound healing, tissue engineering, stem cell therapy, etc.…”
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84
Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches
Published 2019-01-01“…Safe and predictable pharmaceutical means to increase bone formation have been elusive. Stem cell therapy of osteoporosis, as a therapeutic strategy, offers the promise of an increase in osteoblast differentiation and thus reversing the shift towards bone resorption in osteoporosis. …”
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85
Cavernous Nerve Injury Resulted Erectile Dysfunction and Regeneration
Published 2021-01-01“…In addition, such as neuromodulatory proteins, proimmune ligands, gene therapy, stem cell therapy, and the current cutting-edge low-energy shock wave therapy have shown advantages in basic research and limited clinical studies. …”
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86
The effect of the Wnt pathway on the osteogenic differentiation of periodontal ligament stem cells in different environments
Published 2025-01-01“…Periodontal ligament stem cells (PDLSCs) are considered a promising source for stem cell therapy due to their high osteogenic differentiation capability. …”
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87
Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions
Published 2025-01-01“…This review discusses the muscle microenvironment's changes contributing to these conditions, recent therapeutic approaches like lifestyle modifications, small molecules, and nutritional interventions, and emerging strategies such as gene editing, stem cell therapy, and gut microbiome modulation. We also address the challenges and opportunities of multimodal interventions, aiming to provide insights into the pathogenesis and molecular mechanisms of sarcopenia and cachexia, ultimately aiding in innovative strategy development and improved treatments.…”
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88
The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness
Published 2011-01-01“…Therapeutic trials have been performed mainly in the former type including stem cell therapy, retinal transplantation, and development of ocular prosthetics. …”
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89
Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis?
Published 2019-01-01“…A cure is not available at this time, and the disease leads to death within 3–5 years, mainly due to respiratory failure. Stem cell therapy is arising as a new promising approach for the treatment of neurodegenerative disorders. …”
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90
Phases I–III Clinical Trials Using Adult Stem Cells
Published 2010-01-01“…First randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease. …”
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91
Neuroprotective Effects of Stem Cells in Ischemic Stroke
Published 2017-01-01“…However, it is still lacking of efficient agents. Stem cell therapy, with its vigorous advantages, has attracted researchers around the world. …”
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92
Procedural Treatments for Knee Osteoarthritis: A Review of Current Injectable Therapies
Published 2020-01-01“…Small studies have examined prolotherapy and stem cell therapy and demonstrate some benefits. Trials involving genicular nerve block procedures have been successful. …”
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93
Optical and MRI Multimodal Tracing of Stem Cells In Vivo
Published 2023-01-01“…Stem cell therapy has shown great clinical potential in oncology, injury, inflammation, and cardiovascular disease. …”
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94
In Vivo Bioluminescence Imaging of Transplanted Mesenchymal Stem Cells as a Potential Source for Pancreatic Regeneration
Published 2014-10-01“…Stem cell therapy has been studied intensively as a promising therapeutic strategy toward a cure for diabetes. …”
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95
Stem Cells in the Treatment of Neuropathic Pain: Research Progress of Mechanism
Published 2020-01-01“…In this review, we briefly introduce the neuropathic pain, the current treatment strategy, and the development of stem cell therapy, and we collected the experimental and clinical trial articles of many kinds of stem cells in the treatment of neuropathic pain from the past ten years. …”
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96
Mesenchymal Stem Cells Ameliorate Hyperglycemia in Type I Diabetic Developing Male Rats
Published 2022-01-01“…One of the most promising treatments for diabetes mellitus (DM) is stem cell therapy. This study is aimed at elucidating the antidiabetic effect of mesenchymal stem cells (MSCs) on streptozotocin- (STZ-) induced DM in developing male rats. …”
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97
Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine
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98
Functional Multipotency of Stem Cells: What Do We Need from Them in the Heart?
Published 2012-01-01“…Randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease, and several efficacy phase III trials with clinical endpoints are on their way. …”
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99
Stem Cells for Cardiac Repair: Status, Mechanisms, and New Strategies
Published 2011-01-01“…But many clinical trials have shown that the stem cell therapy of heart failure is modest or not effective. …”
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100
The biological and functional restoration of spinal cord injury
Published 2024-12-01“…Restoration of the anatomical structure and microenvironment of the damaged region can be obtained by molecular drug modulation, neuroprotection, neuroregeneration, stem cell therapy, and biomaterial‐based tissue engineering. …”
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