High-dependency unit care after carotid endarterectomy for asymptomatic stenosis by Beatriz Guimarães, Andreia Coelho, Marina Dias-Neto, Ricardo Castro-Ferreira, João Peixoto, Luís Fernandes, Roberto Boal, Marta Machado, Francisco Basílio, Patrícia Carvalho, Armando Mansilha, Alexandra Canedo

“…The remaining variables also did not reach statistical significance. CONCLUSIONS: In this analysis, the risk for CO development was consistently increased in patients who developed high MAP intra-operatively, highlighting the need for scrupulous BP management to reduce potential complications. …”
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Seroprevalence of dengue, Zika, and chikungunya in São Sebastião, Brazil (2020–2021): a population-based survey by Tayane Nobre, Andre Luiz Dutra Fenner, Emerson Luiz Lima Araújo, Wildo Navegantes de Araújo, Emmanuel Roux, Pascal Handschumacher, Helen Gurgel, Bruno Dallago, Mariana Hecht, Luciana Hagström, Walter Massa Ramalho, Nadjar Nitz

“…Participants who tested positive for IgM and/or IgG were classified as soropositive. Statistical analyses included tests for normality, associations, mean comparisons, and correlations. …”
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Comparison of bioabsorbable screw versus metallic screw fixation for tibial tubercle fractures in adolescents: a retrospective cohort study by Tian Chen, Yuwei Wen, Danjiang Zhu, Wei Feng, Baojian Song, Qiang Wang

“…Knee joint function was evaluated using the Lysholm and Tegner scores. Statistical analysis was performed to identify differences between the variables of the two groups. …”
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An updated systematic review with meta-analysis and meta-regression of the factors associated with human visceral leishmaniasis in the Americas by Anna Gabryela Sousa Duarte, Guilherme Loureiro Werneck, Sarah de Farias Lelis, Thays Santos Mendonça, Daniela Dias Vasconcelos, Tiago Silveira Gontijo, Álisson Oliveira dos Santos, Lucas Edel Donato, Vinícius Silva Belo

“…Future research should be conducted with greater statistical power and using molecular diagnostic techniques, preferably involving cohort studies in diverse Latin American countries. …”
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Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up by Fabrizio Giansanti, Cristina Nicolosi, Giuseppe Ruben Barbera, Giulio Vicini, Flavia Lucarelli, Edoardo Traniello Gradassi, Vittoria Murro, Gianni Virgili, Daniela Bacherini

“…The mean BCVA improved at each follow-up time point: it was 0.24 ± 0.16 LogMAR at 1 month, 0.18 ± 0.15 LogMAR at 6 months, and 0.09 ± 0.11 LogMAR at the last follow-up. There was a statistically significant improvement between BCVA at 1 month and BCVA at 6 months and between BCVA at 6 months and BCVA at the last follow-up (<i>p</i> < 0.001). …”
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UGT2B15 single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans by Jin-Woo Park, Jin-Woo Park, Jin-Woo Park, Jong-Min Kim, Young Yoon Bang, Kyoung-Ah Kim, Sungwook Yu, Ji-Young Park

“…Pharmacokinetic parameters were analyzed using non-compartmental methods, and statistical comparisons were conducted between the genotype groups.ResultsUGT2B15 c.253G&gt;T significantly affected free DAB pharmacokinetics, with a lower Tmax and oral clearance in TT genotype (n = 28, p &lt; 0.05). …”
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Comparative safety of transvenous and leadless pacemakers in patients with cardiovascular diseases: A meta-analysis study by Cedric Mhasseb, Mayassa Kiwan, Marie-Elie Merhi, Nicolas Moussallem, Jana Moussalli, Maroun Abou Zeid, Sarah Abou Daher, Ghassan Nabbout, Sami Azar, Amjad Kanaan, Frederic Harb

“…A comprehensive and systematic search was conducted across PubMed, Embase, Cochrane Library, Web of Science and ClinicalTrials.gov, spanning from inception until just before the final analysis. SPSS was used for statistical analysis. Relative risks (RR) and odds ratio (OR) were used to evaluate the outcomes with a 95 % confidence interval (CI). …”
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Effect of a Vibration System on Pain Reduction during Injection of Dental Anesthesia in Children: A Randomized Clinical Trial by Muhanad AlHareky, Jehan AlHumaid, Sumit Bedi, Maha El Tantawi, Mazin AlGahtani, Yousef AlYousef

“…The results showed a statistically significant reduction in pain after the injection for the test group compared with control using VAS scale (mean = 6.68 (1.09) and 8.42 (0.50); p=0.001) and FLACC scale (mean = 5.92 (1.05) and 8.16 (0.54); p=0.002), but not when using SEM scale (mean 3.22 (0.42) and 4.24 (2.74);p=0.08). …”
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Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety by Víctor Mayoral, Rafael Galvez, Marta Ferrándiz, Xoán Miguéns Vázquez, Carlos Cordero-García, Antonio Alcántara Montero, Concepción Pérez, María Pérez-Páramo

“…The risk of bias was evaluated using the Cochrane Review Manager tool. Statistical analysis was performed using Review Manager 5.4.1 software, calculating effect sizes and conducting sensitivity analysis based on medication dosage.ResultsA total of 14 studies with 3,346 patients were analyzed. …”
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Human Papillomavirus Prevalence in Oral and Oropharyngeal Rinse and Gargle Specimens of Dental Patients and of an HIV-Positive Cohort from Pretoria, South Africa by Neil H. Wood, Koketso S. Makua, Ramokone L. Lebelo, Nina Redzic, Ina Benoy, Olivier M. Vanderveken, Johannes Bogers

“…Specimens were analysed for HPV DNA on 3 separate PCR/qPCR platforms. Statistical analyses were performed for associations between the study group and categorical variables, HPV status, and data from the questionnaires. …”
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MRI to digital medicine diagnosis: integrating deep learning into clinical decision-making for lumbar degenerative diseases by Baoyi Ke, Wenyu Ma, Junbo Xuan, Junbo Xuan, Yinghao Liang, Liguang Zhou, Wenyong Jiang, Jing Lin, Guixiang Li

“…Additionally, the testing time of the deep learning program was significantly shorter than that of manual identification, and the differences were statistically significant (P &lt; 0.05).ConclusionsDeep learning technology based on the PP-YOLOv2 algorithm can be used to identify normal intervertebral discs, lumbar disc herniation, and lumbar spondylolisthesis from lumbar MRI images. …”
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Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer by Angelica Nogueira Rodrigues, Andreza Karine de Barros Almeida Souto, Diocésio Alves Pinto de Andrade, Larissa Müller Gomes, Sandra Satie Koide, Renata de Godoy e Silva, Bruno Batista de Souza, Juliana Doblas Massaro, Andréia Cristina de Melo, Andrea Morais Borges, Camila Giro, Carlos Augusto Vasconcelos de Andrade, Cesar Martins da Costa, Daniel Luiz Gimenes, Eduardo Caminha Bandeira de Mello, Fernanda Cesar de Oliveira, Frederico Müller de Toledo Lima, Gabriel Lima Lopes, Gustavo de Oliveira Bretas, Gustavo Guerra Jacob, Herika Lucia da Costa Silva, Juliana Ferrari Notaro, Lara Ladislau Alves, Marcos Veloso Moitinho, Mirian Cristina da Silva, Roberto Abramoff, Thais Amaral da Cunha Rauber, Rodrigo Dienstmann, Fernanda Christtanini Koyama

“…We assessed the performance of the in-house test (GS Focus HRD) using Cohen’s kappa statistic to measure agreement with the gold standard assay (MyChoice® HRD Plus CDx) in HRD status classification, along with other accuracy metrics.ResultsIn total, 41 samples were analyzed (20 HRD-positive, 19 HRD-negative, and 2 inconclusive results with the MyChoice® HRD Plus CDx assay). …”
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Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa [version 2; peer review: 2 approved,... by Robert J Wilkinson, Francisco Lakay, Nicki Tiffin, Joel A Dave, Catherine Riou, Peter Raubenheimer, Anna K Coussens, Tsaone Tamuhla, Melissa J Blumenthal, Maleeka Abrahams

“…Here we demonstrate the feasibility of this approach, recognising that the findings presented here are preliminary and require further validation once we have a sufficient sample size to improve statistical significance of findings. We implemented a genotyped population cohort with virtual follow up data in a resource-constrained African environment, demonstrating feasibility for scale up and novel health discoveries through nested case-control studies.…”
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Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA by Po-Ku Chen, Joung-Liang Lan, Yi-Ming Chen, Hsin-Hua Chen, Shih-Hsin Chang, Chia-Min Chung, Nurul H. Rutt, Ti-Myen Tan, Raja Nurashirin Raja Mamat, Nur Diana Anuar, Jonathan M. Blackburn, Der-Yuan Chen

“…Next, we executed statistically powered autoantibody profiling analysis of 50 samples in Cohort-2 (24 ADAb-positive and 26 ADAb-negative patients). …”
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Psychoeducation of higher education seekers with using of the resource-oriented model of stress resiliency in war conditions by V.V. Ogorenko, A.E. Nikolenko, T.Y. Shusterman, V.O. Kokashynskyi, A.B. Khotimska, M.H. Koren

“…The first stage involved a statistical analysis of resiliency modalities and their average scores in both groups. …”
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Snacking Behaviour and Its Determinants among College-Going Students in Coastal South India by Prasanna Mithra, Bhaskaran Unnikrishnan, Rekha Thapar, Nithin Kumar, Sharana Hegde, Anjali Mangaldas Kamat, Vaman Kulkarni, Ramesh Holla, B. B. Darshan, Kanchan Tanuj, Vasudev Guddattu, Avinash Kumar

“…Data were collected using a pretested pro forma that was coded and analyzed using Statistical Package for Social Sciences (SPSS) version 11.5. …”
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Effectiveness of nurse-led care in patients with rheumatoid arthritis: a systematic review and meta-analysis by Dan Liu, Li Liu, Lin Yang, Ting Wen, Peng Xiang, Guifang Pi

“…When comparing other secondary outcomes (pain, satisfaction, quality of life, fatigue, stiffness, physical function and psychological status), the effectiveness of NLC for RA patients was similar to that of the control group, with no statistically significant differences.Conclusions NLC proves highly effective in managing RA patients, surpassing usual care and equating to rheumatologist-led care in primary and some secondary outcomes. …”
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Association between different modalities of opioid use disorder-related care delivery and opioid use disorder-related patient outcomes: A retrospective cohort study by Nahiyan Bin Noor, George Pro, Mahip Acharya, Hari Eswaran, Corey J. Hayes

“…Receiving OUD-related care primarily through audiovisual visits, compared to in-person care, was associated with a slight increase in the odds of receiving MOUD. No statistically significant differences were found between the care delivery modalities and the other outcomes we examined. …”
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Construction of an Index System of the Biosafety Incident Response Capability for Nursing Staff: A Delphi Study by Chao Wu, Mengyi Hu, Xinyan Zhang, Mimi Fu, Lu Li, Qiang Xu, Xiaolan Guo, Hongjuan Lang

“…The Kendall's harmony coefficients of the two rounds of expert consultation were 0.301–0.384 and 0.401–0.424, respectively, with statistical significance (p < 0.05). Conclusion The index system of the biosafety incident response competence for nursing staff is scientific and reliable. …”
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Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis by Bin You, Bin You, Bin You, Bin You, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen

“…Subgroup analyses did not reveal statistically significant interactions by age, sex, or obesity status, although associations appeared stronger in younger adolescents.ConclusionElevated blood manganese and selenium levels are associated with a higher prevalence of hepatic steatosis in adolescents. …”
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