improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati... by Paul Leighton, Georgette Eaton, Georgie Nicholls, Kacper Sumera, Marishona Ortega, Jessica Hodgson, Michael Baliousis, Aloysius Niroshan Siriwardena, Despina Laparidou, Bill Lord, Sarah Redsell, Gregory Adam Whitley, Tatiana Bujor

“…A five-stage approach will be adopted; 1) Developing an Initial Programme Theory (IPT): develop an IPT with key stakeholder input and evidence from informal searching; 2) Searching and screening: conduct a thorough search of relevant research databases and other literature sources and perform screening in duplicate; 3) Relevance and rigour assessment: assess documents for relevance and rigour in duplicate; 4) Extracting and organising data: code relevant data into conceptual “buckets” using qualitative data analysis software; and 5) Synthesis and Programme Theory (PT) refinement: utilise a realist logic of analysis to generate context-mechanism-outcome configurations (CMOCs) within and across conceptual “buckets”, test and refine the IPT into a realist PT. …”
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Effect of Rifaximin and a Multi-Strain Probiotic on the Intestinal Microbiome and Cardiovascular Risk Indicators in Patients with Coronary Heart Disease by E. A. Kashukh, E. A. Poluektova, A. V. Kudryavtseva, G. S. Krasnov, V. I. Kazey, P. D. Sobolev, P. V. Gremyakova, V. T. Ivashkin

“…The results were analysed using the IBM SPSS 22.0 statistical data processing software.Results. An additional administration of the probiotic (Bifidobacterium bifidum no less than 1x109 CFU; Bifidobacterium longum no less than 1x109 CFU; Bifidobacterium infantis no less than 1x109 CFU; Lactobacillus rhamnosus no less than 1x109 CFU) is found to have no effect on the lipid profile and the platelet aggregation rate. …”
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Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Inter... by Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

“…ObjectiveThis study aims to test the accuracy and validity of a new software in comparison to the gold-standard electrocardiogram (ECG)-based heart rate measurement. …”
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Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives by Sileshi Dubale, Rashed Edris Usure, Yesuneh Tefera Mekasha, Gemmechu Hasen, Firdos Hafiz, Dereje Kebebe, Sultan Suleman

“…The quantitative data were analyzed using Statistical Package for the Social Sciences (SPSS) software version 26, with outputs presented in text, table, and figure form.ResultsThe archival review of the study found that Ethiopia’s THM legislative and regulatory framework is still in a developmental phase, particularly when compared with countries that have more established systems. …”
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Right ventricular myocardial work: proof-of-concept for the assessment of pressure-strain loops of patients with pre-capillary pulmonary hypertension by Bárbara Lacerda Teixeira, Francisco Albuquerque, Raquel Santos, André Ferreira, Ricardo Carvalheiro, João Reis, Luis Almeida Morais, Tânia Mano, Pedro Rio, Ana Teresa Timoteo, Rui Cruz Ferreira, Ana Galrinho

“…In both groups, patients underwent same day RHC and echocardiographic assessment. Dedicated software for left ventricle myocardial work was used for the RV. …”
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Association Between SHBG Levels and Hypertensive Disorders of Pregnancy: A Systematic Review and Meta‐Analysis by Ajay Malvi, Muhammed Shabil, Mahalaqua Nazli Khatib, Roopashree R, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Prasad, Pranchal Rajput, Rukshar Syed, Kamal Kundra, Vinamra Mittal, Amit Kumar, Pancham Cajla, Ganesh Bushi, Rachana Mehta, Zaid Khan, Prakasini Satapathy, Shilpa Gaidhane, Renu Sah

“…Results were pooled using a random‐effects meta‐analysis in R software (V 4.4), with the I2 statistic assessing heterogeneity. …”
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Peripheral blood biomarkers as differential diagnostic markers of disease severity in neonates with hyperbilirubinemia by Dereje Mengesha Berta, Negesse Cherie, Berhanu Woldu, Aregawi Yalew, Elias Chane, Amare Mekuaninnit, Mebratu Tamir, Zufan Yiheyis, Abiy Ayele Angelo, Zewudu Mulatie, Adamu Kassie, Bisrat Birke Teketelew

“…The data were entered into Epi-data (4.6.0) and analyzed by STATA (14) software. The summary statistics were used. The Kruskal Wallis H tests were utilized to compare median differences between groups. …”
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Life cycle assessment and life cycle cost of tofu production and its extended recycling scenario by S. Hartini, A.N. Fatliana, N.U. Handayani, P.A. Wicaksono, B.S. Ramadan, T. Matsumoto

“…Environmental cost was determined using the eco-cost 2023 method, and environmental and economic impacts were examined with SimaPro software version 9.4.FINDINGS: Life cycle assessment analysis revealed eutrophication, carbon footprint, and freshwater ecotoxicity to be the categories with the most significant impact for each process. …”
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Coronavirus Disease 2019-Related Multisystem Inflammatory Syndrome in Children: A Systematic Review and Meta-Analysis by Ji-Gan Wang, Zhi-Juan Zhong, Meng Li, Jun Fu, Yu-Heng Su, You-Min Ping, Zi-Ji Xu, Hao Li, Yan-Hao Chen, Yu-Li Huang

“…High-quality articles were selected for analysis on the basis of their quality standard scores. Using R3.6.3 software, meta-analyses of random- or fixed-effects models were used to determine the prevalence of comorbidities. …”
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COSMIC’s Large-scale Search for Technosignatures during the VLA Sky Survey: Survey Description and First Results by C. D. Tremblay, J. Sofair, L. Steffes, T. Myburgh, D. Czech, P. B. Demorest, R. A. Donnachie, A. W. Pollak, M. Ruzindana, Siemion A. P. V., S. S. Varghese, S. Z. Sheikh

“…In our first paper, we described the system design and software pipelines. In this paper, we describe a postprocessing pipeline to identify persistent sources of interference, filter out false positives, and search for signals not immediately identifiable as anthropogenic radio frequency interference during the VLA Sky Survey. …”
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Mapping the Distribution and Population Status of <i>Alosa immaculata</i> and <i>Alosa tanaica</i> (Teleostei, Clupeidae) in the Bulgarian Black Sea Area by Desislava Rozdina, Yana Stoyanova, Georgi Terziyski, Slavi Studenkov, Boris Karakushev, Venceslav Delov, Konstantin Mihaylov, Dimitar Kozhuharov, Yordan Kutsarov, Nikolay Kolev, Nikolay Nedyalkov, Nikolay Natchev

“…Analysis of the suitability of the occupied habitat of both species was carried out using the MAXENT v 3.4.0 software application. The status of the populations was studied based on the parameters abundance (ind.…”
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SEED (Stoke Disease Early Detection Application) - Rancang Bangun Aplikasi Mobile Berbasis Android untuk Mendiagnosis Gejala Dini Penyakit Stroke Menggunakan K-Nearest Neighbor (K-... by Dedin Anike Putra, Muhammad Dimas Setiawan Sanapiah, Azifatul Istna Hanifah, Tri Afirianto

“…Metode prototyping merupakan salah satu jenis software development lifecycle (SDLC) dalam pengembangan perangkat lunak. …”
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Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis... by Wenji Pu, Wenji Pu, Wenji Pu, Wenqi Chen, Haiman Jing, Jishi Li, Yong Jiang, Shasha Li, Weijie Wen, Zhiyuan Xu, Jing Jin

“…Finally, RevMan 5.4 software was utilized to conduct the meta-analysis for determining the 95% confidence interval (CI) and pooled risk ratio (RR). …”
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A pulsed carbon dioxide laser-induced breakdown analysis for chemical profile of tsunami-affected soil by R. Mitaphonna, N. Idris, M. Ramli, N. Ismail, K. Kurihara, K. Lahna

“…Data is stored for processing with SpectraView software and compared with the National Institute of Standards and Technology database for identification.FINDINGS: The utilization of a pulsed carbon dioxide laser for analysis revealed its superior ability to identify a wider array of elements with high intensity-to-background ratios, particularly excelling in the detection of zinc, chromium, copper, cobalt, and nickel compared to the neodymium-doped yttrium aluminum garnet laser. …”
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Construction of Recombinant Inbred Lines and Indentification of QTL for Grain Number Traits of Gaozhou Wild Rice by Xing HUO, Yongmei YU, Shuqing QIU, Dilin LIU, Le KONG, Wuge LIU, Feng WANG

“…QTL analysis was conducted by using QTL IciMapping software with the combination of phenotypic data and SNP marker information.…”
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Nucleotide variation in Foxp3 gene and prognosis of bladder cancer: a case-control study by Qin Li, Yan Zhang, Yan Zhang, Min Su, Yaping Song, Yanyun Wang, Bin Zhou, Lin Zhang

“…SPSS and online SNPstats software were used to determine the disparities between groups.ResultsFor the rs3761548 C/A polymorphism, patients with the CA/AA genotype showed a notable decrease in the case group (22.1% versus 34.8%, P = 0.003, OR = 0.61, 95%CI = 0.44-0.85), and the heterozygous CA genotype presented a distinctly lower risk for BC (P = 0.0003, OR = 0.43, 95%CI = 0.26-0.70). …”
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Multimodal data deep learning method for predicting symptomatic pneumonitis caused by lung cancer radiotherapy combined with immunotherapy by Mingyu Yang, Jianli Ma, Chengcheng Zhang, Liming Zhang, Jianyu Xu, Shilong Liu, Jian Li, Jiabin Han, Songliu Hu

“…The region of interest (ROI) in the lung parenchyma was outlined separately from the tumor volume, and standard radiomic features were obtained through the use of 3D Slicer software. In addition, the images were cropped to a uniform size of 224x224 pixels. …”
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Identification of the optimal candidates to benefit from surgery and chemotherapy among elderly female breast cancer patients with bone metastases by Yuchen Hu, Junfeng Tang, Xiaofeng Liu, Yusheng Sun, Baojun Gong, Qing Gao

“…Elderly female breast cancer patients with bone metastases from the Surveillance, Epidemiology, and End Results (SEER) database were included in this study and categorized into a training cohort and a validation cohort using R software. To identify independent predictors of OS in this population, both univariate and multivariate Cox regression analyses were conducted. …”
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A qualitative study of stigma in patients with low anterior resection syndrome of rectal cancer (直肠癌低位前切除综合征患者病耻感的质性研究) by WEN Ruizhen (温瑞珍), CHEN Piao (陈飘), LI Yalan (李亚兰), CAO Aifang (曹爱芳), WANG Miaolan (王淼兰), ZHENG XiaoXuan (郑筱暄), PENG Hui (彭慧)

“…The descriptive qualitative study was used to conduct face-to-face semi-constructive interviews with patients, and the recording materials were processed by Nvivo12. 0 software. Results The stigma of patients with LARS can be summarized into three themes. …”
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Standardization of the Agar Plate Method for Bacteriophage Production by Su Jin Jo, Young Min Lee, Kevin Cho, Seon Young Park, Hyemin Kwon, Sib Sankar Giri, Sung Bin Lee, Won Joon Jung, Jae Hong Park, Mae Hyun Hwang, Da Sol Park, Eun Jae Park, Sang Wha Kim, Jin Woo Jun, Sang Guen Kim, Ji Hyung Kim, Se Chang Park

“…Regression models developed with Minitab software established correlations between plaque size and phage production, optimizing production while minimizing resistance development. …”
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