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421
Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immun...
Published 2021-01-01“…We made the following findings: (1) LIUS upregulates proinflammatory IGs and downregulates metastasis genes in cancer cells, and LIUS upregulates adaptive immunity pathways but inhibits danger-sensing and inflammation pathways and promote tolerogenic differentiation in bone marrow (BM) cells. (2) LIUS upregulates IGs encoded for proteins localized in the cytoplasm, extracellular space, and others, but downregulates IG proteins localized in nuclear and plasma membranes, and LIUS downregulates phosphatases. (3) LIUS-modulated IGs act partially via several important pathways of reactive oxygen species (ROS), reverse signaling of immune checkpoint receptors B7-H4 and BTNL2, inflammatory cytokines, and static or oscillatory shear stress and heat generation, among which ROS is a dominant mechanism. (4) LIUS upregulates trained immunity enzymes in lymphoma cells and downregulates trained immunity enzymes and presumably establishes trained tolerance in BM cells. (5) LIUS modulates chromatin long-range interactions to differentially regulate IGs expression in cancer cells and noncancer cells. …”
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422
Modeling of a cracked and repaired Al 2024T3 aircraft plate: effect of the composite patch shape on the repair performance
Published 2019-10-01“…The obtained results show that in the first case, the patch shape have no effect on the SIF, the sharp edges (obtuse, right and acute) of oblique shapes generate high shear stresses, in the second case, the reduced surfaces lead to significant mass gain with the same SIF values. and to an increase in the maximum shear stresses, in the latter case the patches shapes lead to a reduction of the SIF and the shear stresses.…”
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423
Modeling of a cracked and repaired Al 2024T3 aircraft plate: effect of the composite patch shape on the repair performance
Published 2019-07-01“…The obtained results show that in the first case, the patch shape have no effect on the SIF, the sharp edges (obtuse, right and acute) of oblique shapes generate high shear stresses, in the second case, the reduced surfaces lead to significant mass gain with the same SIF values. and to an increase in the maximum shear stresses, in the latter case the patches shapes lead to a reduction of the SIF and the shear stresses.…”
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424
Peristaltic Flow of a Magneto-Micropolar Fluid: Effect of Induced Magnetic Field
Published 2008-01-01“…Expressions for the shear stresses are also obtained. The effects of pertinent parameters on the pressure rise per wavelength are investigated by means of numerical integrations, also we study the effect of these parameters on the axial pressure gradient, axial-induced magnetic field, as well as current distribution across the channel and the nonsymmetric shear stresses. …”
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425
Simulation of Pulsatile Flow of Blood in Stenosed Coronary Artery Bypass with Graft
Published 2006-01-01“…Distributions ofvelocity, pressure and wall shear stresses are determined undervarious conditions. …”
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426
Static and dynamic behaviors of laminated composite plates resting on elastic foundation
Published 2022-02-01“…Among the advantages of this new theory it takes into consideration the shearing effect in the calculation of deformation without the need for shear correction factors and giving rise to a variation of the shear stresses along the thickness and satisfying the zero shear stresses condition in faces of the plate. …”
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427
Determination of the critical plane orientation depending on the fatigue curves for bending and torsion
Published 2017-06-01“…The paper also contains a verification of the effectiveness of the proposed model by analyzing scatter bands and the value of the ratio of normal to shear stresses.…”
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428
Determination of the critical plane orientation depending on the fatigue curves for bending and torsion
Published 2017-07-01“…The paper also contains a verification of the effectiveness of the proposed model by analyzing scatter bands and the value of the ratio of normal to shear stresses.…”
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429
Physical and mathematical model of working process of the Hartmann–Sprenger tube
Published 2022-03-01“…The proof of the influence of viscosity and shear stresses on the occurrence of transfer of kinetic energy from the incident flow to the flow entering the dead-end cavity is given. …”
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430
Effect of branchings on blood flow in the system of human coronary arteries
Published 2011-11-01“…The magnitude ofwall shear stresses rises at the bifurcation.…”
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431
On Flows of Bingham-Type Fluids with Threshold Slippage
Published 2017-01-01“…We investigate a mathematical model describing 3D steady-state flows of Bingham-type fluids in a bounded domain under threshold-slip boundary conditions, which state that flows can slip over solid surfaces when the shear stresses reach a certain critical value. Using a variational inequalities approach, we suggest the weak formulation to this problem. …”
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432
Influence of control parameters on the crack paths in the aluminum alloy 2024 under bending
Published 2015-09-01“…Tests with controlled energy parameter amplitude allow observing crack growth depending on maximum shearing stress surface. Tests with controlled bending moment amplitude allowed observing two types of crack paths.…”
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433
Influence of control parameters on the crack paths in the aluminum alloy 2024 under bending
Published 2015-10-01“…Tests with controlled energy parameter amplitude allow observing crack growth depending on maximum shearing stress surface. Tests with controlled bending moment amplitude allowed observing two types of crack paths…”
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434
Investigation on parametric representation of proportional and nonproportional multiaxial fatigue responses
Published 2016-06-01“…Parametric representations for both normal and shear stresses and strains were obtained by plotting them in polar figures. …”
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435
Analysis of the Composite Transmission of Magnetorheological Fluids and Shape Memory Alloy
Published 2015-01-01“…The magnetorheological effect of magnetorheological fluid reduce under a high temperature condition,which causes so many problems like the uncontrollability of the variation of shearing stress,and even failure of the transmission device.Based on the rheological property of magnetorheological fluid and the temperature characteristics of shape memory alloy,a composite transmission device of magnetorheological fluid and shape memory alloy is designed,which rely on magnetorheological fluid to transfer torque under a lower temperatures condition,shape memory alloy spring assisted power transmission when the magnetorheological performance reduce under a high temperature condition.The performance of drive force transmission device is analyzed,and the formula of power transmission of transmission device is derived.The study results show that the composite transmission device can work at the external magnetic field and the temperature control,the torque can maintain continuous,controllable under a high temperature condition,the stability and efficiency of transmission device are improved.…”
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436
Investigation on parametric representation of proportional and nonproportional multiaxial fatigue responses
Published 2016-07-01“…Parametric representations for both normal and shear stresses and strains were obtained by plotting them in polar figures. …”
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437
Study of stress-strain state of wheelset of freight car during braking
Published 2019-12-01“…It is shown that the maximum shear stresses are observed at a point located at a depth of 4,5–5,3 mm below the surface of the wheel. …”
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438
IMPACT OF HARDENING ON J INTEGRAL AT THE SLIGHTLY CURVED ELASTICITY-PLASTICITY CRACK TIP UNDER QUASI-STATIC LOADS
Published 2016-01-01“…J integral of elastic-plastic curved crack in hardened material under quasi-static loads has been mainly studied,and curved crack tip J integral has been calculated as a practical application of a second order perturbation method and theorem of surname KA,where the effects of quasi-static applied stresses and quasi-static normal and shear stresses on the boundaries of plasticity area are synthetically taken into considerations. …”
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439
Numerical simulations of irreversibility for nonlinearly radiative and chemically reactive flow of Maxwell fluid
Published 2025-01-01“…Also, unsteadiness in the flow, porosity and magnetic effects enhance the shearing stress on the surface leading to greater surface friction while solar radiation and surface heating due to nonlinearity in radiative force favour the heat transferable rate leading to an improvement in convection rate. …”
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440
A Novel Approach to Design Chitosan-Polyester Materials for Biomedical Applications
Published 2012-01-01“…Grafting of polyester moieties onto chitosan chains was found to occur under employed pressures and shear stresses. The prepared polymer blends have demonstrated an amphiphilic behavior with a propensity to disperse in organic solvents that widens possibilities to transform them into promising materials for various biomedical applications.…”
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