Exposure to triphenyl phosphate during pregnancy: The role of gut-bile acids-liver axis on lipid metabolism in male offspring by Juntong Lin, Fuhui Yan, Longhui Liu, Ganzhong Liao, Yilei Xu, Qian Liu, Miaoliang Wu, Honghui Guo, Bai Zhi, Lianxian Guo, Xiaoshan Liu

“…Previously, we found that gestational and lactational TPhP exposure disturbed lipid metabolism and gut microbiota in offspring sex-dependently. In this study, we further explored the prenatal TPhP exposure on lipid metabolism in male offspring, and the role of gut-bile acids-liver axis in it. …”
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Childhood lung function is associated with adolescent-onset and persistent asthma by Hans Jacob L. Koefoed, Anhar Ullah, Jenny Hallberg, Simon Kebede Merid, Maura M. Kere, Lesley Lowe, Angela Simpson, Clare S. Murray, Ulrike Gehring, Roel Vermeulen, Inger Kull, Anna Bergström, Judith M. Vonk, Adnan Custovic, Erik Melén, Gerard H. Koppelman

“…A higher FEV1/FVC at age 8 years was associated with a lower odds for asthma persistence in adolescence (0.96 (0.93–0.99)). Sex by lung function interaction analysis was not significant. …”
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Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021Research in context by Yuzhe Pan, Qian Liu, Nan Zhang, Shuang Peng, Xinqi Li, Fuling Zhou

“…LMM analysis identified sex, age, year, SDI region, and leukemia subtype as significant QCI determinants. …”
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The association between short-term apparent temperature exposure and human coagulation: A time-series study from Beijing, 2014–2023 by Yi Zhang, Tiancheng Wang, Jiaqi Shi, Ying Ma, Nairui Yu, Xinyan Zhou, Pai Zheng, Zhangjian Chen, Guang Jia

“…Logistic regression analysis revealed that the risk of hypercoagulable state increased in both high and low temperature environments compared to moderate temperatures, with a significant increase observed under extreme heat conditions. Subgroup analyses by sex and age, sensitivity analyses, and the external validation indicated that the association between AT and coagulation was robust. …”
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Proton therapy versus conventional radiotherapy for the treatment of cavernous sinus benign meningioma, a randomized controlled phase III study protocol (COG-PROTON-01) by Paul Lesueur, Benedicte Clarisse, Justine Lequesne, Idlir Licaj, Loic Feuvret, Dinu Stefan, Damien Ricard, Georges Noel, Jacques Balosso, Marie Lange, Aurelie Capel, Isabelle Durand-Zaleski, Marie Castera, Berenice Legrand, Nicolas Goliot, Camille Hedou, Jean Michel Grellard, Samuel Valable

“…Eligible patients with low-grade cavernous sinus meningioma will be 1:1 randomised, with stratification on age, sex, MoCA score. Overall, the inclusion of 160 patients is planned (80 in each arm). …”
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Population genetics of Glossina fuscipes fuscipes from southern Chad by Ravel, Sophie, Mahamat, Mahamat Hissène, Ségard, Adeline, Argilés-Herrero, Rafael, Bouyer, Jérémy, Rayaisse, Jean-Baptiste, Solano, Philippe, Guihini Mollo, Brahim, Pèka, Mallaye, Darnas, Justin, Belem, Adrien Marie Gaston, Yoni, Wilfrid, Noûs, Camille, De Meeûs, Thierry

“…The trapping samples were characterized by a strong female biased sex-ratio, except in Timbéri and Dokoutou that had high tsetse densities. …”
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Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials by Zhaokai Jin, Yi Tang, Hua Huang, Lei Chen, Zhongyi Zhang, Tianyou Ma, Zhengming Wang, Hai Su, Haojing Zhou, Shuaijie Lv, Peijian Tong

“…Finally, 32 trials involving 2292 patients were included, the mean age of the enrolled patients was ~69.10 years, the sex ratio of males was (31.6%), and the longest follow‐up time was 2 years. …”
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The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Random... by Jarrod L. Thomas, Kirsty C. McGee, Anower Hossain, Gavin D. Perkins, Anthony C. Gordon, Duncan Young, Danny McAuley, Mervyn Singer, Ranjit Lall, Tina Kramaric, Janet M. Lord, Tony Whitehouse, Luis A. J. Mur, for the STRESS-L. collaborators

“…The individual-level models were adjusted for confounders, such as age, sex, noradrenaline dosage and patient (random effect). …”
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Long-term outcomes of robot-assisted versus minimally invasive esophagectomy in patients with thoracic esophageal cancer: a propensity score-matched study by Toru Sakurai, Akihiro Hoshino, Kenta Miyoshi, Erika Yamada, Masaya Enomoto, Junichi Mazaki, Hiroshi Kuwabara, Kenichi Iwasaki, Yoshihiro Ota, Shingo Tachibana, Yutaka Hayashi, Tetsuo Ishizaki, Yuichi Nagakawa

“…These variables included age, sex, body mass index, alcohol consumption, smoking history, American Society of Anesthesiologists stage, comorbidities, tumor location, histology, clinical TNM stage, and preoperative therapy. …”
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Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a... by Kagbadouno, Moise S, Séré, Modou, Ségard, Adeline, Camara, Abdoulaye Dansy, Camara, Mamadou, Bucheton, Bruno, Bart, Jean-Mathieu, Courtin, Fabrice, De Meeûs, Thierry, Ravel, Sophie

“…In variance with a significant impact of VCC on the apparent densities of flies captured in the traps deployed, the global population of G. p. gambiensis displayed no variation of the sex-ratio, no genetic signature of control, and behaved as a very large population occupying the entire zone. …”
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Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study by Xue Li, Youqing Wang, Huizhang Li, Le Wang, Juan Zhu, Chen Yang, Lingbin Du

“…Key factors identified for the prediction model and risk score system included age (hazard ratio [HR] 1.06, 95% CI 1.04‐1.08), sex (male: HR 3.41, 95% CI 2.44‐4.78), education level (medium: HR 0.84, 95% CI 0.61‐1.15; high: HR 0.37, 95% CI 0.17‐0.78), cirrhosis (HR 11.93, 95% CI 7.46‐19.09), diabetes (HR 1.59, 95% CI 1.08‐2.34), and hepatitis B surface antigen (HBsAg) status (positive: HR 3.84, 95% CI 2.38‐6.19; unknown: HR 1.04, 95% CI 0.73‐1.49). …”
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Predictive Factors and the Predictive Scoring System for Falls in Acute Care Inpatients: Retrospective Cohort Study by Chihiro Saito, Eiji Nakatani, Hatoko Sasaki, Naoko E Katsuki, Masaki Tago, Kiyoshi Harada

“…In the training dataset (n=9150), Cox regression analysis identified sex (male: HR 1.60, 95% CI 1.21‐2.13), age (65 to <80 years: HR 2.26, 95% CI 1.48‐3.44; ≥80 years: HR 2.50, 95% CI 1.60‐3.92 vs 20-<65 years), BMI (18.5 to <25 kg/m²: HR 1.36, 95% CI 0.94‐1.97; <18.5 kg/m²: HR 1.57, 95% CI 1.01‐2.44 vs ≥25 kg/m²), independence degree of daily living for older adults with disabilities (bedriddenness rank A: HR 1.81, 95% CI 1.26‐2.60; rank B: HR 2.03, 95% CI 1.31‐3.14; rank C: HR 1.23, 95% CI 0.83‐1.83 vs rank J), department (internal medicine: HR 1.23, 95% CI 0.92‐1.64; emergency department: HR 1.81, 95% CI 1.26‐2.60 vs department of surgery), and history of falls within 1 year (yes: HR 1.66, 95% CI 1.21‐2.27) as predictors of falls. …”
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Emerging malaria in Indonesia: An overview of Plasmodium knowlesi infections by Nisa Fauziah, Karomahul Malaya Jati, Fedri Ruluwedrata Rinawan, Naufal Fakhri Nugraha, Bachti Alisjahbana, Jontari Hutagalung

“…Conclusions: Two major Indonesian islands of Sumatra and Kalimantan, which reported malaria cases during the period studied, exhibit a potential risk for P. knowlesi infections that is influenced by factors beyond natural hosts and vectors, such as sex, age, and occupation. Routine PCR examinations for suspected P. knowlesi infections are crucial for developing effective strategies to identify and control this simian malaria parasite.…”
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Metabolic syndrome in type 1 diabetes: higher time above range and glycemic variability revealed by continuous glucose monitoring (CGM) by Yayu Fang, Wei Liu, Xiaoling Cai, Yu Zhu, Mingxia Zhang, Siqian Gong, Xiangqing Wang, Chu Lin, Rui Zhang, Sai Yin, Juan Li, Yongran Huo, Xiaodan Hu, Xiaoqi Xie, Linong Ji

“…And the Logistic regression analysis showed that TAR (OR 1.53, 95% CI 1.02–2.23, per 20% increase), SD ( OR 1.75, 95% CI 1.07–2.84, P = 0.025) and IQR (OR 1.50, 95% CI 1.03–2.19, P = 0.036) were positively associated with metabolic syndrome after adjusting for age, sex, diabetes duration, BMI and complication status. …”
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Contribution of integrase inhibitor use, body mass index, physical activity and caloric intake to weight gain in people living with HIV by Giovanni Guaraldi, Jovana Milic, Elena Bacchi, Federica Carli, Marianna Menozzi, Iacopo Franconi, Alessandro Raimondi, Giacomo Ciusa, Valentina Masi, Michela Belli, Stefano Guaraldi, Emanuele Aprile, Maria Mancini, Cristina Mussini, Jordan E. Lake, Kristine M. Erlandson

“…Groups were matched for sex, age, baseline BMI and follow-up duration. Significant WG was defined as an increase of ≥5% from 1st visit weight over follow-up. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…No significant differences were observed in age, sex, CGA, duration of symptoms, disease severity, overall 30-day-mortality, or reinfection between “induced” and “non-induced” residents. …”
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The Role of Human Agency in Global Urban Health by Kai Michael Gensitz, Catherine Woods, Tadhg MacIntyre, Claudio R. Nigg

“…Results As core SEC in the Global Urban Health concept, every individual brings certain biological (e.g., genes, age, sex, physiology), sociodemographic (e.g., cultural background, education level, socioeconomic status), psychosocial (e.g., motivations, attitudes, self-efficacy, intentions, emotions, stress), and behavioral (e.g., physical activity, diet, pro-environmental actions) factors with them. …”
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The First 24 h Hemodynamic Management in NICU after Revascularization Surgery in Moyamoya Disease by Jie Song, Yu Lei, Long Chen, Chao Gao, Wei Ni, Xing Wu, Gang Wu, Ying Mao, Jin Hu, Yuxiang Gu

“…What is more, a higher early postoperative Hb level also seemed to predict a worse long-term clinical outcome (favorable group 116.9±17.1 g/L vs. unfavorable group 123.7±13.0 g/L, p=0.03), but the difference disappeared after adjusting sex and age. Logistic regression analyses showed that a higher level of postoperative MAP (β=0.024, 95% CI (0.004, 0.044), and p=0.02) within the first 24 h in NICU might be the short-term risk factor. …”
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Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients by Katharina Bell, Vanessa M. Beutgen, Stefan Nickels, Katrin Lorenz, Yvonne Scheller, Hisham Elbaz, Tunde Peto, Katharina A. Ponto, Andreas Schulz, Philipp S. Wild, Thomas Münzel, Karl J. Lackner, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Franz H. Grus, Alexander K. Schuster

“…Optic nerves of RVO subjects and age- and sex-matched controls (n = 229) at baseline and their follow-up examination after 5 years were analyzed for glaucomatous alterations. …”
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QUIET WARRIOR – Rationale and design: An ancillary study to the Women's IschemiA TRial to Reduce Events in Nonobstructive CAD (WARRIOR) by Osama Dasa, Eileen Handberg, Damini Dey, Pinaki Sarder, Margaret C. Lo, Balaji K. Tamarappoo, Steven M. Smith, Leslee J. Shaw, C. Noel Bairey Merz, Carl J. Pepine

“…In many cases, coronary angiography does not reveal obstructive coronary artery disease (CAD) despite increased risk for major adverse cardiac events (MACE) compared with sex and age-matched asymptomatic cohorts. Objectives: The Women's IschemiA TRial to Reduce Events in Nonobstructive CAD (WARRIOR) evaluates intensive medical treatment for women with Ischemia with No Obstructive Coronary Arteries (INOCA). …”
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