Showing 2,241 - 2,260 results of 10,378 for search '"sequencing"', query time: 0.11s Refine Results
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    Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR by Sang-Yu Lu, Ying-Chao Chen, Jia-Lin Feng, Qin-Yi Zhou, Jing Chen, Chen-Fang Zhu, Miao-Miao Guo, Man-Man Zhang, Qian-Yue Zhang, Meng Lu, Liu Yang, Jing Wu, Shuang-Xia Zhao, Huai-Dong Song, Xiao-Ping Ye

    Published 2022-01-01
    “…Conclusion. ddPCR has higher sensitivity than Sanger sequencing and we propose ddPCR as a supplement to Sanger sequencing in molecular testing of BRAF using FNAB samples.…”
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  6. 2246
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    RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis by Rebecca P. Duncan, Gina R. Lewin, Daniel M. Cornforth, Frances L. Diggle, Ananya Kapur, Dina A. Moustafa, Yasmin Hilliam, Jennifer M. Bomberger, Marvin Whiteley, Joanna B. Goldberg

    Published 2025-01-01
    “…In addition, while samples sequenced with different sequencing pipelines showed significantly more variance in expression profiles than between labs, gene expression was still highly reproducible between sequencing pipelines. …”
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  8. 2248

    Adaptive evolution of SARS-CoV-2 during a persistent infection for 521 days in an immunocompromised patient by Hanno Schmidt, Lea Schick, Jürgen Podlech, Angélique Renzaho, Bettina Lieb, Stefan Diederich, Thomas Hankeln, Bodo Plachter, Oliver Kriege

    Published 2025-01-01
    “…Virus samples from five time points were submitted to whole genome sequencing. Between the first detection of SARS-CoV-2 infection and its clearance, the patient’s virus population acquired 34 amino acid substitutions and 8 deletions in coding regions. …”
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  9. 2249

    AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples by Hyeonseong Jeon, Junhak Ahn, Byunggook Na, Soona Hong, Lee Sael, Sun Kim, Sungroh Yoon, Daehyun Baek

    Published 2023-08-01
    “…In this study, we constructed a substantially extended set of actual positive variants originating from a wide range of tumor purities and sequencing depths, as well as actual negative variants derived from sequencer-specific sequencing errors. …”
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  10. 2250

    Integrated Network Pharmacology and Gut Microbiota Study on the Mechanism of Huangqin Decoction in Treatment Diabetic Enteritis by Xiaomin Xu, Cheng Fang, Fang Lu, Shumin Liu

    Published 2022-01-01
    “…Using network pharmacology and gut microbiota sequencing to investigate the probable mechanism of Huangqin decoction in the treatment of Diabetic enteritis (DE). …”
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  11. 2251

    Challenges and considerations of genetic testing in von Willebrand disease by Omid Seidizadeh, Luciano Baronciani, Flora Peyvandi

    Published 2025-01-01
    “…With the introduction of next-generation sequencing, genetic analysis of the VWF has become more practical than it was in the past, when Sanger sequencing was used. …”
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  12. 2252

    Sekwencjonowanie genomu/eksomu człowieka - aspekt bioetyczny by Andrzej Kochański

    Published 2014-03-01
    “…The technological breakdown in molecular genetics relies on the change of perspective from the analysis of a single gene to the whole genome sequencing (WGS) or whole-exome sequencing (WES). The exome is defined as a coding part of the genome consisting of the coding parts (exons) of all genes. …”
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    Think twice: how single-cell suspensions from solid tissues for single-cell transcriptomics are well prepared by Meng-Meng Qu, Yan-Mei Jiao, Haijuan Wang

    Published 2025-01-01
    “…Due to its technological advantages, single-cell sequencing has become an increasingly utilized tool to unravel the heterogeneity and complexity of individuals. …”
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    Epigenetic Application of ATAC-Seq Based on Tn5 Transposase Purification Technology by Wangchun Li, U Tim Wu, Yu Cheng, Yanhao Huang, Lipeng Mao, Menghan Sun, Congling Qiu, Lin Zhou, Lijuan Gao

    Published 2022-01-01
    “…Assays of transposase accessible chromatin sequencing (ATAC-seq) is an efficient assay to investigate chromatin accessibility, which depends on the activity of a robust Tn5 transposase to fragment the genome while cutting in the sequencing adapters. …”
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  17. 2257

    COVID-19 Whole-Genome Resequencing with Redundant Tiling PCR and Subtract-Based Amplicon Normalization Successfully Characterized SARS-CoV-2 Variants in Clinical Specimens by Tatsuki Sugi, Mizanur Rahman, Rummana Rahim, Abu Hasan, Naoko Kawai, Kyoko Hayashida, Junya Yamagishi

    Published 2022-01-01
    “…With an increasing number of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) sequences gathered worldwide, we recognize that deletion mutants and nucleotide substitutions that may affect whole-genome sequencing are accumulating. …”
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  18. 2258

    De Novo Assembly of the Pea (Pisum sativum L.) Nodule Transcriptome by Vladimir A. Zhukov, Alexander I. Zhernakov, Olga A. Kulaeva, Nikita I. Ershov, Alexey Y. Borisov, Igor A. Tikhonovich

    Published 2015-01-01
    “…The large size and complexity of the garden pea (Pisum sativum L.) genome hamper its sequencing and the discovery of pea gene resources. …”
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  19. 2259

    Establishment of performance parameters for the Qubit™ 1X dsDNA HS Assay for use in forensic genetics casework by Adele Lauren Kaleigh Naidoo, Donna-Lee Pamela Martin, Laura Jane Heathfield

    Published 2025-07-01
    “…Next generation sequencing is being more regularly used in forensic casework, particularly for post-mortem genetic analyses in sudden unexpected death cases. …”
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  20. 2260

    A generative adversarial network for multiple reads reconstruction in DNA storage by Xiaodong Zheng, Ranze Xie, Xiangyu Yao, Yanqing Su, Ling Chu, Peng Xu, Wenbin Liu

    Published 2024-12-01
    “…Specially this situation is even more serious in the 3rd generation of sequencing technologies. Different from previous error-correction and multiple sequence alignment methods, we first transform the multiple reads into a noisy mage, and then construct a conditional generative adversarial network to produce a “smooth” image which refers to the consensus sequence. …”
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