Excess mortality and associated community risk factors related to hurricane Maria in Puerto Rico by Kristen N Cowan, Diego E Zavala, Erick Suarez, José A Lopez-Rodriguez, Omar Alvarez

“…Results: In the 6 months following Maria there were increases in mortality risk for cardiovascular disease, Alzheimer’s, diabetes, sepsis, chronic respiratory disease, hypertension and all-cause mortality. …”
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LIPS and PaO2/FiO2 Combined Plasma Biomarkers Predict Onset of Acute Respiratory Distress Syndrome in Patients of High Risks in SICU: A Prospective Exploratory Study by Ziyuan Shen, Zhongnan Yin, Senhao Wei, Zhukai Cong, Feng Zhao, Hua Zhang, Xi Zhu

“…Univariate analysis found 15 risk factors showed differences between ARDS and non-ARDS, namely, interleukin 6, interleukin 8 (IL-8), angiopoietin Ⅱ, LIPS, APACHEⅡ, SOFA, PaO2/FiO2, age, sex, shock, sepsis, acute abdomen, pulmonary contusion, pneumonia, hepatic dysfunction. …”
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Factors Associated with Maternal Near Miss among Women Admitted in West Arsi Zone Public Hospitals, Ethiopia: Unmatched Case-Control Study by Fikadu Nugusu Dessalegn, Feleke Hailemichael Astawesegn, Nana Chea Hankalo

“…The major maternal near-miss morbidities were severe obstetric hemorrhage (32.5%), pregnancy-induced hypertensive disorders (31.3%), and obstructed labor (26.3%), followed by 6.3% and 3.8% of severe anemia and pregnancy-induced sepsis, respectively. The odds of maternal near miss were statistically significantly associated with women’s lack of formal education [AOR=2.24, 95% CI: (1.17, 4.31)]. …”
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Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women by Katja Graf, José Martin Murrieta-Coxca, Tobias Vogt, Sophie Besser, Daria Geilen, Tim Kaden, Tim Kaden, Anne-Katrin Bothe, Diana Maria Morales-Prieto, Behnam Amiri, Behnam Amiri, Stephan Schaller, Ligaya Kaufmann, Martin Raasch, Ramy M. Ammar, Ramy M. Ammar, Christian Maass, Christian Maass

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Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning... by Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma

“…Abstract Background Bloodstream infection (BSI) is a systemic infection that predisposes individuals to sepsis and multiple organ dysfunction syndrome. Early identification of infectious agents and determination of drug-resistant phenotypes can help patients with BSI receive timely, effective, and targeted treatment and improve their survival. …”
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Navigating complex arterial reconstruction in living donor liver transplantation: the role of the splenic artery as a viable conduit by Hosam Hamed, Mohamed Elshobary, Tarek Salah, Ahmad M. Sultan, El-sayed Abou El-Magd, Ahmed M. Elsabbagh, Ahmed Shehta, Mohamed Abdulrazek, Waleed Elsarraf, Mohamed A. Elmorshedi, Mostafa Abdelkhalek, Usama Shiha, Hassan Magdy Abd El Razek, Mohamed Abdel Wahab

“…Mortality in this cohort was 30%, one of them was due to thrombosis of the conduit and the other two died from sepsis-related complications. With a median follow-up of 43 months, this technique was associated with a 70% survival rate. …”
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Poor Glycemic Control in Carbapenem-Resistant Klebsiella pneumoniae Infections: Impact on Epidemiological Features, Mortality Risks, and Polymyxin Resistance by Wang Q, Yan T, Ma C, Teng X, Shen C, Wang N, Yu K, Chu W, Zhou Q, Liu Z

“…Logistic regression analysis identified age, glycosylated hemoglobin (HbA1c) ≥ 7%, CKD, tumor, mechanical ventilation, and sepsis as independent risk factors for death associated with CRKP infection. …”
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Early- and Late-Onset Preeclampsia: A Comprehensive Cohort Study of Laboratory and Clinical Findings according to the New ISHHP Criteria by Anna Wójtowicz, Małgorzata Zembala-Szczerba, Dorota Babczyk, Monika Kołodziejczyk-Pietruszka, Olga Lewaczyńska, Hubert Huras

“…Children born to women with EOP had lower Apgar scores (p<0.001) and higher rates of intraventricular hemorrhage (p<0.0001), respiratory disorders requiring mechanical ventilation (p<0.0001), and early (p=0.0004) and late sepsis (p=0.002). EOP differed from LOP in terms of maternal and perinatal adverse outcomes. …”
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Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review by Tingting Wang, Xin Huang, Shujun Sun, Yafeng Wang, Linlin Han, Tao Zhang, Tianhao Zhang, Xiangdong Chen

“…Key findings highlight neuroinflammation, oxidative stress, mitochondrial dysfunction, neurotransmitter imbalances, microvascular changes, and white matter lesions as central to PND pathophysiology, with particular parallels to encephalocele- and sepsis-associated cognitive impairments. Among these, neuroinflammation, mediated by pathways such as the NLRP3 inflammasome and blood–brain barrier disruption, emerges as a pivotal driver, triggering cascades that exacerbate neuronal injury. …”
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Synthesis and characteristics of Fe/Ni/Cr oxide nanoparticles/PLA hybrid composite coatings on Mg–Zn–Ca alloy by Prakash Kumar, Aditya Kudva S, AnilKumar T, Ramesh S, M.R. Ramesh, Ashwini Prabhu, Gajanan Anne

“…Coleus amboinicus is known for its various medicinal properties, including immunoregulatory effects, antimicrobial activity, anti-inflammatory properties, and potential use in treating sepsis and other ailments. The extracted FeNiCr was used the develop composite coatings on Mg–4Zn–1Ca alloy. …”
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Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review by Suélia de Siqueira Rodrigues Fleury Rosa, Mário Fabrício Fleury Rosa, Marcos Augusto Moutinho Fonseca, Glécia Virgolino da Silva Luz, Carlos Federico Domínguez Avila, Aldira Guimarães Duarte Domínguez, Aldene Guimarães Duarte Dantas, Von Braun Richter

“…Patients with such diseases often have higher sepsis, infection, and complication rates, since they have revascularization inhibition and low growth factor expression. …”
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Qualitative comparison of decalcifiers for mouse bone cryosections for subsequent biophotonic analysis by Shibarjun Mandal, Ramya Motganhalli Ravikumar, Astrid Tannert, Annett Urbanek, Rustam R. Guliev, Max Naumann, Sina M. Coldewey, Uta Dahmen, Lina Carvalho, Luís Bastião Silva, Ute Neugebauer

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Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy by Ya Qiu, Yan Ma, Min Jiang, Sulei Li, Jibin Zhang, Haixu Chen, Mengqi Xu, Shan Gao, Lei Tian, Bo Tao, Yabin Wang, Dong Han, Feng Cao

“…Endotoxemia in sepsis remains a problem due to a lack of effective strategies. …”
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Biometrías fetales y variables maternas como predictores de desviaciones de la condición trófica al nacer by Disney Borrego Gutierrez, Elizabeth Alvarez Guerra González, Nélida Liduvina Sarasa Muñoz, Danay Vázquez Rivero, Celidanay Ramírez Mesa, Calixto Orozco Muñoz

“…Las gestantes de peso adecuado preponderaron en cada condición al nacer, los recién nacidos pequeños se relacionaron con los trastornos hipertensivos durante el embarazo, la sepsis vaginal y la diabetes mellitus mientras que los recién nacidos grandes predominaron en madres con la glucemia alterada y anemia. …”
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Rapid and sensitive detection of Haemophilus influenzae using multiple cross displacement amplification combined with CRISPR-Cas12a-based biosensing system by Xinbei Jia, Wenjian Xu, Fei Xiao, Nan Jia, Xiaolan Huang, Yiqin Zhang, Juan Zhou, Yi Wang, Jun Tai

“…Haemophilus influenzae (H. influenzae, Hi) is an opportunistic bacterium that colonizes the upper respiratory tract of humans and frequently causes meningitis, pneumonia, sepsis, and other severe infections in children. Early and accurate detection of H. influenzae is essential for effective diagnosis and treatment. …”
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Phenotypic and genetic extended spectrum beta lactamase profiles of bacterial isolates from ICU in tertiary level hospital in Kenya [version 2; peer review: 2 approved] by Edwin O. Magomere, Lucy Muchiri, Leon Otieno, Frank G. Onyambu, Ali Kassim, Job Mwale, Brian Maina

“…Their vulnerable immunity predisposes them to developing bacteria-associated sepsis, deteriorating their already fragile health. …”
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Correction: HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

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Effect of Prolonged-Release Pirfenidone on Renal Function in Septic Acute Kidney Injury Patients: A Double-Blind Placebo-Controlled Clinical Trial by Jonathan S. Chávez-Iñiguez, Jorge L. Poo, Miguel Ibarra-Estrada, Leonel García-Benavides, Guillermo Navarro-Blackaller, Cynthia Cervantes-Sánchez, Eduardo Nungaray-Pacheco, Ramón Medina-González, Juan Armendariz-Borunda, Guillermo García-García

“…This study was a double-blind randomized clinical trial in sAKI patients with nephrology consultation at the Civil Hospital of Guadalajara, in addition to the usual treatment of AKI associated with sepsis; patients were randomized to receive either PR-PFD at 1,200 mg/day (group A) or 600 mg/day (group B) or a matched placebo for 7 consecutive days. …”
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Altered CD73-Adenosine Signaling Linked to Infection in Patients undergoing hemodialysis by Xiang F, Zhang Z, Nie Y, Cao X, Li Y, Chen X, Gong S, Zou J, Teng J, Ding X, Shen B

“…In addition, a 5/6 nephrectomy (5/6 Nx) rat model and cecal ligation and puncture (CLP) were used to verify the effect of chronic kidney disease (CKD) and sepsis on CD73-adenosine signaling.Results: Decreased CD73+ T cells were independently associated with increased infection risk over one and three years. …”
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Outcome of Newborns with Tracheoesophageal Fistula: An Experience from a Rapidly Developing Country: Room for Improvement by Amal Al-Naimi, Sara G. Hamad, Abdalla Zarroug

“…Immediate postoperative complications were encountered in eleven patients (33%) and included anastomosis leak in 12%, air leak in 6%, sepsis in 6%, chylothorax in 3%, vocal cord palsy and fistula recurrence (combined) in 3%, and failure of TEF closure in 3% of the patients. …”
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