Hipoalbuminemia y riesgo de muerte en pacientes críticos en una unidad polivalente by Giovanna Silvia Quispe Alarcón, Yanín Díaz Lara, Jorge Soneira Pérez, Sergio González García, Hedgar Berty Gutiérrez

“…Se ha asociado con la mortalidad hospitalaria en pacientes con complicaciones postquirúrgicas, pacientes con sepsis y trauma. Objetivo: Evaluar la asociación entre los niveles de hipoalbuminemia y el riesgo de mortalidad del paciente crítico en una unidad polivalente. …”
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Concordancia clínico-patológica en fallecidos en el Hospital Pediátrico de Cienfuegos (2000-2015) by Jorge Luis Capote Padrón, Yusimí García Mena, Ariel Efrén Uriarte Méndez, Alnilam Fernández González, Darian Polls Machado, Dunia María Chávez Amaro

“…<br /><strong>Resultados</strong>: las enfermedades infecciosas predominaron en todos los grupos de edades, y fueron las neumonías y la sepsis, las más frecuentes. El síndrome de disfunción múltiple de órganos fue la afección más descrita como causa directa de muerte, vinculado no solo a enfermedades infecciosas, pues también se manifestó como evento final. …”
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Carga económica de la enfermedad neumocócica en niños de edad preescolar en el Policlínico Cecilio Ruiz de Zárate Castellón. 2016 by Martha Marrero Araújo, Anai García Fariñas, Ana María Gálvez González

“…Los atendidos en el nivel primario después de un egreso hospitalario tuvieron un costo médico directo medio de 106,96 CUP; en los casos con otitis media aguda fue de 89,83 CUP y para aquellos egresados luego de una meningitis o sepsis fue de 152,63 CUP con el mayor valor de costo medio, mínimo y máximo debido a la prolongación de la atención posterior al egreso. …”
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Different Modulating Effects of Adenosine on Neonatal and Adult Polymorphonuclear Leukocytes by Pei-Chen Hou, Hong-Ren Yu, Ho-Chang Kuo, Lin Wang, Li-Yan Lin, Jiunn-Ming Sheen, Te-Yao Hsu, Chia-Yu Ou, Yi-Jyun Jheng, Kuender D. Yang, Wen-Hsin Cheng

“…Adenosine may not be a good strategy for the treatment of neonatal sepsis because of impaired phagocyte reactions and poor response.…”
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Norepinephrine Infusion and the Central Venous Waveform in a Porcine Model of Endotoxemic Hypotension with Resuscitation: A Large Animal Study by Zachary R. Bergman, Roy K. Kiberenge, Richard W. Bianco, Gregory J. Beilman, Colleen M. Brophy, Kyle M. Hocking, Bret D. Alvis, Eric S. Wise

“…Using a porcine model of distributive shock and fluid resuscitation, we sought to determine the influence of norepinephrine on f0 of the central venous waveform.Methods Eight pigs were anesthetized, catheterized and treated with norepinephrine after precipitation of endotoxemic hypotension, and subsequent fluid resuscitation to mimic sepsis physiology. Hemodynamic parameters and central venous waveforms were continually transduced throughout the protocol for post-hoc analysis. …”
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Using verbal and social autopsy approaches to understand why neonates die in rural settings: a case study of a remote rural district in Uganda by Peter Waiswa, Rornald Muhumuza Kananura, Dinah Amongin, Joseph Akuze, Jacquellyn Nambi Ssanyu, Felix Kizito

“…The primary causes of death were birth asphyxia (42.4%), low birth weight/prematurity (18.6%), other perinatal causes (12.8%) and neonatal sepsis (9.3%). Delays in getting appropriate care at the facility (delay 3) and delays in seeking care (delay 1) (51.2% and 44.2%, respectively) were linked to newborn mortality. …”
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Preoperative myosteatosis and perioperative serum chloride levels predict 180 day major complications after radical cystectomy by Wassapol Sornthai, Achiraya Teyateeti, Tawatchai Taweemonkongsap, Siros Jitpraphai, Varat Woranisarakul, Kantima Jongjitaree, Katunyou Mahamongkol, Nattaporn Wanvimolkul, Thitipat Hansomwong

“…Among the cohort, 30.7% of patients experienced major complications within 90 days, and 36.2% within 180 days. Sepsis was the most common major complication (19 of 241 complications, 7.9%). …”
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A real-world Pharmacovigilance study of brodalumab based on the FDA adverse event reporting system by Ke He, Kaidi Zhao, Tingyi Yin, Meng Liu, Jiashu Liu, Wenqian Du, Xinyi Liu, Baochen Cheng, Dewu Zhang, Yan Zheng

“…Additionally, we found potential adverse reactions not noted on the drug’s label that exhibited positive signals, including depression, increased blood pressure, peripheral swelling, gait disturbance, inability to walk, stress, myocardial infarction, sepsis, uveitis, nephrolithiasis, and interstitial lung disease. …”
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Association between diabetes mellitus and total hip arthroplasty outcomes: an observational study using the US National Inpatient Sample by Jasvinder A Singh, Sumanth Chandrupatla, Kranti Rumalla

“…Primary THA hospitlizations were analysed as the overall group and also stratified by the underlying primary diagnosis for THA.Outcome measures Outcome measures of interest were the length of hospital stay&gt;the median, total hospital charges&gt;the median, inpatient mortality, non-routine discharge, need for blood transfusion, prosthetic fracture, prosthetic dislocation and postprocedural infection, including periprosthetic joint infection, deep surgical site infection and postprocedural sepsis.Results Among 2 467 215 patients who underwent primary THA, the mean age was 68.7 years, 58.3% were female, 85.7% were white, 61.7% had Medicare payer and 20.4% had a Deyo-Charlson index (adjusted to exclude diabetes mellitus) of 2 or higher. 416 850 (17%) patients had diabetes. …”
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Usefulness of presepsin as a prognostic indicator for patients with trauma in the emergency department in Korea: a retrospective study by Si Woo Kim, Jung-Youn Kim, Young-Hoon Yoon, Sung Joon Park, Bo Sun Shim

“…Presepsin is a novel biomarker of inflammation that can predict a poor prognosis in patients with sepsis. This study aimed to determine whether presepsin could be used as a prognostic indicator in patients with polytrauma. …”
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Comparative Outcomes of Meropenem–Vaborbactam vs. Ceftazidime–Avibactam Among Adults Hospitalized with an Infectious Syndrome in the US, 2019–2021 by Marya D. Zilberberg, Brian H. Nathanson, Mark A. Redell, Kate Sulham, Andrew F. Shorr

“…CZA, we conducted a multicenter retrospective cohort study of all adult hospitalized patients with a serious infection (sepsis, urinary tract infection [UTI], complicated intraabdominal [cIAI] infection, or pneumonia) within the PINC AI Database, 2019–2021. …”
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The Efficacy of Parenteral Nutrition and Enteral Nutrition Supports in Traumatic Brain Injury: A Systemic Review and Network Meta-Analysis by Yan Qin, Maoxia Liu, Fengbao Guo, Du Chen, Peng Yang, Xionghui Chen, Feng Xu

“…In addition, the complications including pneumonia and sepsis have no statistical difference between EN and PN. …”
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Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy by Pei-Pei Liu, Xin-Yue Yu, Qing-Qing Pan, Jia-Jun Ren, Yu-Xuan Han, Kai Zhang, Yan Wang, Yin Huang, Tao Ban

“…Background/Objectives: Septic cardiomyopathy (SCM) is a severe cardiac complication of sepsis, characterized by cardiac dysfunction with limited effective treatments. …”
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The burden of group A Streptococcus (GAS) infections: The challenge continues in the twenty-first century by Aswin Thacharodi, Saqib Hassan, Avadh Vithlani, Tawfeeq Ahmed, Sanjana Kavish, Nicole-Mae Geli Blacknell, Ali Alqahtani, Arivalagan Pugazhendhi

“…GAS produces a variety of virulence factors and exotoxins that can lead to deadly infections such as necrotizing fasciitis, impetigo, cellulitis, pneumonia, empyema, streptococcal toxic shock syndrome, bacteremia, and puerperal sepsis. In addition, post-immune mediated disorders such as post-streptococcal glomerulonephritis, acute rheumatic fever, and rheumatic heart disease contribute to extremely high death rates in developing nations. …”
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Randomised trials in maternal and perinatal health in low and middle-income countries from 2010 to 2019: a systematic scoping review by Joshua P Vogel, Jack Williams, Tari Turner, Steve McDonald, Alexander John Eggleston, Annabel Richards, Elise Farrington, Wai Chung Tse, Ayeshini Sella Hewage

“…Within these trials, pre-existing medical conditions, embolism, obstructed labour and sepsis were all under-represented when compared with number of maternal deaths globally. …”
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Persistent Mortality Risk From Device-related Healthcare-associated Infection in Kidney Transplant Recipients Despite Multifaceted Interventions Action Calls for a Zero-tolerance P... by Maria Bethânia Peruzzo, MD, Luana Oliveira Calegari, MSc, Renato Demarchi Foresto, MD, PhD, Helio Tedesco-Silva, MD, PhD, José Medina Pestana, MD, PhD, Lúcio Requião-Moura, MD, PhD

“…Additional variables associated with increased risk of death included age (HR, 1.03; P < 0.001), baseline immunosuppression (HR based on mycophenolate versus others 0.74; P = 0.02), time since transplantation (HR, 1.003; P < 0.001), platelet count at ICU admission (HR, 0.998; P < 0.001), and sepsis as the reason for ICU admission (HR, 1.67; P < 0.001). …”
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Private sector delivery of care for maternal and newborn health: trends over a decade in the Indian state of Bihar by G. Anil Kumar, Sibin George, Moutushi Majumder, S. Siva Prasad Dora, Md Akbar, Tanmay Mahapatra, Rakhi Dandona

“…Birth asphyxia was the leading cause of death in 2016 (37.8%) and 2020–2021 (33.9%) followed by preterm delivery and neonatal pneumonia; a statistically significant reduction was seen in meningitis/sepsis between 2016 and 2020–2021 (77.8%; 95% CI = − 145.4 to − 10.1). …”
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Diabetes and Hemoglobin A1c as Risk Factors for Nosocomial Infections in Critically Ill Patients by Eirini Tsakiridou, Demosthenes Makris, Vasiliki Chatzipantazi, Odysseas Vlachos, Grigorios Xidopoulos, Olympia Charalampidou, Georgios Moraitis, Epameinondas Zakynthinos

“…Independent risk factors for BSI in ICU included BSI on admission 2.45 (1.14–5.29; P=0.022) and stroke on admission2.77 (1.12–6.88; P=0.029). Sepsis 3.34 (1.47–7.58; P=0.004) and parenteral feeding 6.29 (1.59–24.83; P=0.009) were independently associated with ICU mortality. …”
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Frequency and risk factors of retinopathy of prematurity: a 5-year single-center study in a Tertiary Care Hospital by Maaly Abdel Fattah, Anas AlKhabaz, Ibrahim Issa, Hadeel Alhemsi, Kassem AlSaad, Eyad AlMidani, Faisal Khan

“…Neonatal complications: Chronic lung diseases [(respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD)], sepsis, neonatal jaundice, patent ductus arteriosus (PDA), hydrocephalus, and intraventricular hemorrhage (IVH). …”
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In Vivo Evaluation of the Ameliorating Effects of Small-Volume Resuscitation with Four Different Fluids on Endotoxemia-Induced Kidney Injury by Yan-ling Wang, Jing-hui Chen, Qiong-fang Zhu, Gao-feng Yu, Chen-fang Luo, Gang-jian Luo, Shang-rong Li, Zi-qing Hei

“…Acute kidney injury associated with renal hypoperfusion is a frequent and severe complication during sepsis. Fluid resuscitation is the main therapy. However, heart failure is usually lethal for those patients receiving large volumes of fluids. …”
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