Clostridium septicum Gas Gangrene in Colon Cancer: Importance of Early Diagnosis by Sowmya Nanjappa, Sweta Shah, Smitha Pabbathi

“…Tumor-induced mucosal ulceration allows for translocation of sporulated bacteria from the bowel into the bloodstream, leading to fulminant sepsis. C. septicum bacteremia can have a variable presentation and is associated with greater than 60% mortality rate. …”
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The Frequency Of Maternal Near Misses At Benazir Bhutto Hospital- Using The WHO Standard Tool, A Cross-Sectional Study by Humaira Masood, Tallat Farkhanda, Sadia Khan, Ismat Batool, Nighat Naheed, Hina Gul

“…The major causes of maternal near-miss (MNM) were postpartum haemorrhage n=25 ( 29.7 %), followed by hypertensive disorders n=23 (27.3%). At the same time, sepsis and hypertension were the main reasons for maternal death. …”
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Calciphylaxis: A Long Road to Cure with a Multidisciplinary and Multimodal Approach by Vasiliki Zoi, Dimitra Bacharaki, Aggeliki Sardeli, Minas Karagiannis, Sophia Lionaki

“…Calciphylaxis is a rare yet potentially fatal condition, resulting from ectopic calcification of the small arterioles of the dermis with resulting necrotic lesions infection, sepsis, and death. In hemodialysis patients, its prevalence ranges between 1 and 4%, while mortality amounts to 30–80%. …”
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Polyarticular Septic Arthritis Caused by Haemophilus influenzae Serotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature by Raheel Ahmed Ali, Sheldon L. Kaplan, Scott B. Rosenfeld

“…Haemophilus influenzae non-type b may cause serious invasive infections such as sepsis or septic arthritis in children with or without predisposing factors such as immunodeficiency or asplenia. …”
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Monitoring of perioperative tissue perfusion and impact on patient outcomes by Bin Li, Yuchen Dai, Wenlan Cai, Menghan Sun, Jie Sun

“…Central venous oxygen saturation offers a better systemic overview but may not always indicate good perfusion, especially in sepsis. Lactic acid levels closely correlate with tissue perfusion and outcomes, with dynamic changes being more indicative than single measurements. …”
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Staphylococcus aureus Infections in the Paediatric Intensive Care Unit: Illustrated Cases by Kam Lun Hon, Ronald C. M. Fung, Karen K. Y. Leung, Alexander K.C. Leung, Wun Fung Hui, Wing Lum Cheung

“…Staphylococcus aureus is known to be one of the most common gram-positive microorganisms and an important pathogen associated with sepsis and toxic shock. We present four anonymized consecutive cases in a paediatric intensive care unit (PICU) to illustrate the different clinical manifestations of staphylococcal infections, including local infection versus systemic infection, toxic shock versus septic shock, and osteomyelitis. …”
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TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms by René Huber, Rolf Bikker, Bastian Welz, Martin Christmann, Korbinian Brand

“…Otherwise, tolerance may also be a trigger of immune paralysis thus contributing to severe inflammatory diseases such as sepsis. An improved understanding of TNF tolerance will presumably facilitate the implementation of diagnostic or therapeutic approaches to more precisely assess and treat inflammation-related diseases.…”
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Cognitive Biases in the Era of COVID-19 : A Case of Clostridium sporogenes Bacteremia in a Patient with Small Bowel Obstruction by Marc J. Vecchio, Matthew Jankowich, Hassan Qadir, Melissa Gaitanis, Anupama Menon

“…Routine monitoring of prognostic inflammatory markers for COVID-19 created a unique challenge in the management of our patient who developed sepsis with respiratory symptoms. Upon review, bacteremia from Clostridium sporogenes was associated with high mortality rates and could produce similar elevations in the inflammatory markers observed in COVID-19 pneumonia. …”
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Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases by Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin

“…RAGE signaling and downstream pathways have been implicated in a wide spectrum of inflammatory-related pathologic conditions such as arteriosclerosis, Alzheimer's disease, arthritis, acute respiratory failure, and sepsis. Despite the significant progress in other RAGE studies, the functional importance of the receptor in clinical situations and inflammatory diseases still remains to be fully realized. …”
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The Effect of Conventional and Mini-Invasive Cardiopulmonary Bypass on Neutrophil Activation in Patients Undergoing Coronary Artery Bypass Grafting by Martina Kolackova, Jan Krejsek, Vladimir Svitek, Pavel Kunes, Jiri Mandak, Zdenka Holubcova, Vladimir Lonsky

“…Interleukin-10 (IL-10) is considered to be a cytokine with potent anti-inflammatory properties, which have been previously linked to increased incidence of sepsis. The level of IL-10 is elevated by cardiac surgery when cardiopulmonary bypass (CPB) and methylprednisolone are used. …”
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The Impact of Polyunsaturated Fatty Acid Supplementation on Inflammatory Markers in Preterm Infants – A Literature Review by Larysa Bielecka

“…Research consistently shows that PUFA supplementation lowers IL-6 levels, a cytokine considered a risk factor for sepsis in preterm infants. Conclusion Supplementation with polyunsaturated fatty acids holds potential for modulating inflammatory processes in preterm infants, with efficacy likely influenced by factors such as the specific type of fatty acid used, timing and form of administration, and individual variations in response.  …”
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Diagnostic Accuracy of Immunologic Biomarkers for Accurate Diagnosis of Bloodstream Infection in Patients with Malignancy: Procalcitonin in Comparison with C-Reactive Protein by Mansoureh Shokripour, Navid Omidifar, Kourosh Salami, Mohsen Moghadami, Babak Samizadeh

“…For PCT, the cutoff value of 1.17 ng/ml (bacteremia from nonbacteremia) had the highest NPV value of 91.5% in malignant patients, suspicion of sepsis.…”
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Hib Vaccines: Past, Present, and Future Perspectives by Adi Essam Zarei, Hussein A. Almehdar, Elrashdy M. Redwan

“…Haemophilus influenzae type b (Hib) causes many severe diseases, including epiglottitis, pneumonia, sepsis, and meningitis. In developed countries, the annual incidence of meningitis caused by bacteria is approximately 5–10 cases per population of 100,000. …”
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Cholesterol Prognostic Value in Severe Postoperative Patient´s Morbidity and Mortality by Daymara del Río Bazán, Maricela Morera Pérez, Georgia Díaz-Perera Fernández

“…<br /><strong>Results:</strong> the percentage of complications, sepsis, the APACHE scale and the length of stay were greater in patients with the presence of hypercholesterolemia. …”
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Bench Surgery for Urolithiasis in Renal Transplant: A Sensible Option!! by Abhiyutthan Singh Jadaon, Chandra Pal Singh

“…Urolithiasis in the to be transplanted kidney of donor is considered a relative contraindication due to the complications from stone in recipients like infection leading to sepsis, urinary tract obstruction, and also loss of allograft function. …”
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Surgery for chronic pyothorax after failed amplatzer closure of bronchopleural fistula by Yohann Vincent, Alessandra Lenzini, Amir Hanna, Nicolas Leymarie, Brendan Le Picault, Elie Fadel

“…Conclusion The utilisation of an Amplatzer device to close a broncho-pleural fistula can have adverse effects and potentially result in fatal sepsis in those cases where it is unsuccessful. The endoscopic treatment of BPF should be reserved for expert centers, considering the location, size, and stability of the fistula when choosing the treatment strategy. …”
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A Delayed Diagnosis of Hemorrhagic Shock in a Patient with Alcoholic Cirrhosis and Ascites on Bedside Ultrasound by Madeline Bach, Julian Choi, Rory A. Smith, Sarkis Arabian

“…Bedside ultrasound revealed moderate ascites and as there was no evidence of active bleeding, his shock was attributed to sepsis due to SBP. A bedside paracentesis was performed which revealed gross blood. …”
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A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease by Abdulrahman Ahmad, Ali Albaghli, Adel Michael, Khaled Refaat, Mohammad Omar, Ahmad Ibrahim, Bahaa Elmenshawy, Ashraf Maher, Rasha Alramah, Sami Mikhail, Mustafa Almahmid, Husain Alenezi, Yahya Elshebiney

“…Moreover, using biopsy as a diagnostic tool is controversial, due to the high risk of poor wound healing and sepsis. Radiological studies usually reveal extensive calcification of branching vessels such as penile arteries, eventually leading to gangrene formation in extremities and penis. …”
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Morbimortality in Patients Undergone an Operation for Intestinal Occlusion in General Surgery Service by Alexander Marchena Rodríguez, Reinaldo Jiménez Prendes, Julio César Sarmiento Sánchez

“…The more frequent complications were unbalance hydroelectrolític and sepsis. The principal fatal causes were: mesenteric thrombosis and disorders for hydroelectrolític unbalance, with predominance of the female sex and patients of 65 years and more. …”
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Characteristics of the obstetric patient in critical stage in Cienfuegos province. by Bárbara Lucía Cabezas Poblet, Yoel Valle, María Antonia Cabezas Poblet, Esteban Hernández Barrios, Rolando T. Espín González

“…The principal cause of admission at the ICU was hypovolemic shock, pre eclampsia - eclampsia and sepsis. The major amounts of patients were discharged alive. …”
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