Effect of gestational age on clinical features in necrotizing enterocolitis-associated intestinal perforation by Minming Chen, Wei Feng, Jinping Hou, Xiaohong Die, Zhenhua Guo, Yi Wang

“…Furthermore, GA, sepsis, coagulopathy, CHD, and diseased bowel segment are independent factors for poor prognosis of patients with NEC-IP.…”
Get full text

Hospital burden of pneumococcal disease in Spain (2016–2022): A retrospective study by Ruth Gil-Prieto, Valentín Hernandez-Barrera, Patricia Marín-García, Alba González-Escalada, Ángel Gil-de-Miguel

“…The case fatality rates for pneumococcal pneumonia, meningitis, and sepsis were 7.9%, 10.6%, and 19.8%, respectively. …”
Get full text

Prevalence and Management of Septic Shock among Children Admitted at the Kenyatta National Hospital, Longitudinal Survey by Varsha Vekaria-Hirani, Rashmi Kumar, Rachel N. Musoke, Ezekiel M. Wafula, Idris N. Chipkophe

“…Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have not been adopted in our setting. …”
Get full text

Skin and Soft Tissue Infections in Patients with Solid Tumours by Diamantis P. Kofteridis, Antonios Valachis, Eirini Koutsounaki, Sofia Maraki, Eleni Mavrogeni, Foteini N. Economidou, Dimitra Dimopoulou, Kostas Kalbakis, Vassilis Georgoulias, George Samonis

“…Five patients (7%) died due to sepsis. None was neutropenic. Severe sepsis on admission (𝑃=0.002) and prior blood transfusion (𝑃=0.043) were independent predictors of treatment failure. …”
Get full text

Therapeutic Drug Monitoring of Vancomycin in Hemodialysis Patients in a Hospital in North-East Romania by Aurelia Crețu, Luanda Irina Mititiuc, Iulia-Daniela Lungu, Mihaela Mihaila, Irina Dima, Adrian Covic, Cristina Mihaela Ghiciuc

“…Hemodialysis patients are very fragile patients and the presence of CVCs increases the risk of sepsis. We conducted a prospective study, evaluating the needs of changes in vancomycin dosing for treatment based on the use of the new 2020 vancomycin dosing guidelines, to increase drug safety (preventing subtherapeutic or supratherapeutic doses and offering therapeutic concentrations of the drug) in a particular group of patients with sepsis caused by catheter infections and being on intermittent hemodialysis. …”
Get full text

Effect of Negative Pressure Therapy on the Inflammatory Response of the Intestinal Microenvironment in a Porcine Septic Model by Kenneth C. Norbury, Mary Pat Moyer

“…In a swine model of ischemia/reperfusion injury coupled with sepsis, we have previously shown attenuation of secondary organ injury and decreased mortality with negative pressure therapy (NPT). …”
Get full text

Prognostic Value of the Red Blood Cell Distribution Width-to-Albumin Ratio in Critically Ill Older Patients with Acute Kidney Injury: A Retrospective Database Study by Lei Guo, Dezhun Chen, Bihuan Cheng, Yuqiang Gong, Benji Wang

“…The risk of AKI is complicated when RRT occurs; sepsis and septic shock increase with RA levels.…”
Get full text

Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β,... by André L. F. Sampaio, Jesmond Dalli, Vincenzo Brancaleone, Fulvio D'Acquisto, Mauro Perretti, Carmen Wheatley

“…NOS/•NO inhibitors are potential therapeutics for sepsis, yet they increase clinical mortality. However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory mediators during the immune response to sepsis. …”
Get full text

Profile of Candida bloodstream infections among blood culture-positive patients at a tertiary care hospital by S. Shreya, K. Sandhya Bhat

“…Automated blood cultures are the gold standard tools for the evaluation of suspected cases of sepsis. This study was done to document the proportion of candidemia, Candida profile, susceptibility to fluconazole, and associated risk factors among suspected cases of sepsis. …”
Get full text

Impact of rapid antibiotic susceptibility testing for Gram-negative bacteremia varies by pathogen type and resistance: a secondary analysis of the RAPIDS GN trial by Ritu Banerjee, Abhigya Giri, Lauren Komarow, Maria Souli, Sarah B. Doernberg, Robin Patel

“…This analysis of patients with sepsis previously enrolled in a randomized controlled clinical trial demonstrates that rapid susceptibility testing of bacteria from blood cultures had the greatest impact for patients with antibiotic-resistant infections. …”
Get full text

The maternal morbidity behavior during the puerperium. Cienfuegos, 2020 by Dayami Elizabet Díaz Hurtado, Yuliett Mora Pérez, Luciano Nuñez Almoguea, Yuliemi Basso Basso Mora

“…The postpartum women with maternal morbidity due to severe sepsis were 79 women (2.2%) and with non-serious morbidity 397 women (11.1%). …”
Get full text

Complement activated granulocytes can cause autologous tissue destruction in man by E. Löhde, H. Raude, M. Lück, E. Kraas, W. Lierse

“…Activation of polymorphonuclear granulocytes (PMNs) by C5a is thought to be important in the pathogenesis of multiple organ failure during sepsis and after trauma. In our experiment exposure of human PMNs to autologous zymosan activated plasma (ZAP) leads to a rapid increase in chemiluminescence. …”
Get full text

Risk Factor-Specific Mortality Analysis of the Outborn Newborns to Improve the Neonatal Mortality Rate: A Cross-Sectional Descriptive Study by Tapan K. Kundu, Abhilash Chatterjee, Mitali Bera, Aditi Chowdhury, Riya Guchhait

“…The causes of death were sepsis in 35.23%, perinatal asphyxia in 22.78%, and prematurity (<28 weeks) and ELBW (≤999 grams) in 16.73%. …”
Get full text

Balancing inflammation: the specific roles of serum amyloid A proteins in sterile and infectious diseasese by Tirthankar Mohanty, Katarina Miličević, Henri Göthert, Andreas Tillmann, Médea Padra, Praveen Papareddy, Heiko Herwald

“…SAA-/- mice carrying a deletion of the Saa1, Saa2, Saa3, and Saa4 serum amyloid A genes have better survival rates in sterile sepsis but are more prone to bacterial sepsis than their SAA+/+ counterparts, emphasizing their dual functionality in immune regulation. …”
Get full text

When Do Newborns Die? Timing and Cause-Specific Neonatal Death in Neonatal Intensive Care Unit at Referral Hospital in Gedeo Zone: A Prospective Cohort Study by Akine Eshete, Sileshi Abiy

“…We found that 34.0% and 64.3% of deaths occurred during the first and second weeks of neonatal life, respectively. Neonatal sepsis and low birth weight were the main causes of death and hospital admission. …”
Get full text

Behavior of Newborns Weighing less than 1 800 g by Betsy Rodríguez González, Jorge Luis Felpeto Fuentes

“…<strong><br />Conclusion:</strong> the incidence of low weight and ventilation was poor, a predominance of males, the weight group of 1 402 to 1 800 g, gestational age from 32 to 36 weeks and within the main causes of death were sepsis and intraventricular hemorrhage, and survival was obtained properly.…”
Get full text

Lemierre’s syndrome in a 16-year-old man associated with resolution of marked widespread ST elevation and a normal troponin level by Sylvia Amini, Salim Meghjee, Muhammad Rahim Khan

“…He was initially treated for sepsis, however, subsequent imaging and blood cultures confirmed the diagnosis of Lemierre’s syndrome (LS). …”
Get full text

Neonatal mortality outcome and trends: A 6-year retrospective analysis from a North Indian teaching college hospital by Ritu Rakholia, Mohd Maroof, Damini Kharkwal, Gurpreet Singh

“…Further targeted intervention to tackle preventable cause, such as perinatal asphyxia, sepsis, better antenatal care, and better management of preterm neonates on mission mode, is need of the hour as they continue to contribute significantly to neonatal mortality.…”
Get full text

Visfatin Amplifies Cardiac Inflammation and Aggravates Cardiac Injury via the NF-κB p65 Signaling Pathway in LPS-Treated Mice by Yewen Hu, Nan Wu, Weiping Du, Shuangshuang Wang, Jian Wang, Chaoxia Zhang, Xiaomin Chen, Caijie Shen

“…This study aims at determining the role of visfatin in sepsis-induced cardiac injury and identify its possible mechanisms. …”
Get full text

Prevalence and Temporal Distribution of Extrasystoles in Septic ICU Patients: The Feasibility of Predicting Fluid Responsiveness Using Extrasystoles by Johannes Enevoldsen, Cristhian Potes, Minnan Xu-Wilson, Simon T. Vistisen

“…The aim of this study was to estimate the availability of extrasystoles in intensive care unit patients diagnosed with sepsis. The study aim was not to validate the fluid responsiveness prediction ability of extrasystoles. …”
Get full text