Bloodstream Infection Etiology among Children and Adults by Svetlana I. Kolesnichenko, Alyona V. Lavrinenko, Lyudmila L. Akhmaltdinova

“…Every year in the world, sepsis occurs in 31.5 million people, and the number of deaths reaches 5.3 million per year. …”
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Dynamic Monitoring of sTREM-1 and Other Biomarkers in Acute Cholangitis by Jiahui Jiang, Xiaolei Wang, Tongtong Cheng, Mingyue Han, Xinxin Wu, Haitong Wan, DaojunYu

“…Background. Sepsis is a common complication of acute cholangitis (AC), which is associated with a high mortality rate. …”
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Role of Complement in Multiorgan Failure by Daniel Rittirsch, Heinz Redl, Markus Huber-Lang

“…Multiorgan failure (MOF) represents the leading cause of death in patients with sepsis and systemic inflammatory response syndrome (SIRS) following severe trauma. …”
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The Risk Factors for Mortality among Septic Trauma Patients: A Retrospective Cohort Study Using the National Trauma Data Bank by Nadim Kattouf, Mohamad Assaf, Saadeddine Haidar, Rana Bachir, Mazen El Sayed, Ralph BouChebl

“…In trauma patients, the development of sepsis as a hospital complication is significantly associated with morbidity and mortality. …”
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Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Mean Platelet Volume-to-Platelet Count Ratio as Biomarkers in Critically Ill and Inj... by Dragan Djordjevic, Goran Rondovic, Maja Surbatovic, Ivan Stanojevic, Ivo Udovicic, Tamara Andjelic, Snjezana Zeba, Snezana Milosavljevic, Nikola Stankovic, Dzihan Abazovic, Jasna Jevdjic, Danilo Vojvodic

“…There was no significant difference of investigated biomarkers between survivors and nonsurvivors in trauma patients with and without sepsis except for PLR in the trauma without sepsis subgroup (significantly higher in nonsurvivors, AUC/ROC of 0.719). …”
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Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice by Ayana N. Martin, Martha Alexander-Miller, Barbara K. Yoza, Vidula Vachharajani, Charles E. McCall

“…Whether SIRT1 inhibition during sepsis treatment concomitantly reverses innate and T cell antigen-specific immune tolerance is unknown. …”
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Morbidity and Mortality in Preterm Infants following Antacid Use: A Retrospective Audit by Natasha Singh, Aparna Dhayade, Abdel-Latif Mohamed, Tejasvi Vasant Chaudhari

“…Information regarding late onset sepsis, NEC, mortality, ranitidine/omeprazole use, and other neonatal/hospital factors was collected for each neonate. …”
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MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling by Shengfeng Zhang, Qingniao Zhou, Youcheng Li, Yunli Zhang, Yinmei Wu

“…Gut barrier dysfunction with alterant mucosal permeability during sepsis is a challenge problem in clinical practice. …”
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Hemovigilance data: An effective approach for evaluating bacterial protection systems for platelet transfusions by Meshari I. Alabdullatif

“…MATERIALS AND METHODS: HV data with definite transfusion-associated bacterial sepsis in PCs were obtained from Australia, Canada, the United Kingdom (U. …”
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Bedside hyperspectral imaging for the evaluation of microcirculatory alterations in perioperative intensive care medicine: a study protocol for an observational clinical pilot stud... by Thilo Hackert, Thomas Bruckner, Maximilian Dietrich, Sebastian Marx, Felix Nickel, Beat Peter Müller-Stich, Markus A Weigand, Florian Uhle, Thorsten Brenner, Karsten Schmidt

“…We aim to evaluate the effectiveness of HSI for bedside monitoring of skin microcirculation and the association of HSI parameters with organ dysfunction in patients with sepsis and major abdominal surgery.Methods and analysis Three independent groups will be assessed and separately analysed within a clinical prospective observational study: (1) 25 patients with sepsis or septic shock (according to sepsis-3 criteria), (2) 25 patients undergoing pancreatic surgery and (3) 25 healthy controls. …”
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Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review by Deepak Sharma, Ankur Patel, Priyanka Soni, Pradeep Sharma, Basudev Gupta

“…The novelty of the case report is that this is the first case report of neonatal sepsis caused by Empedobacter brevis.…”
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Why do we use transpulmonary thermodilution and pulmonary artery catheter in severe shock patients? by Xavier Monnet, Christopher Lai, Daniel De Backer

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Neuropsychiatric Lupus and Lupus Nephritis Successfully Treated with Combined IVIG and Rituximab: An Alternative to Standard of Care by Mohamed M. Cheikh, Abdullah K. Bahakim, Moayad K. Aljabri, Saad M. Alharthi, Sanad M. Alharthi, Abdullah K. Alsaeedi, Saad F. Alqahtani

“…There is a paucity of evidence to support the co-management of SLE with major organ involvement and sepsis. We describe the clinical response of a 35-year-old male diagnosed with SLE; then, he developed severe sepsis and a flare of SLE with major organ involvement including lupus nephritis (LN), myocarditis, and neuropsychiatric systemic lupus erythematosus (NPSLE). …”
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Sinonasal Melioidosis in a Returned Traveller Presenting with Nasal Cellulitis and Sinusitis by Rebecca Sin Mei Lim, Sam Flatman, Markus C. Dahm

“…We illustrate a case involving a 51-year-old man who presented to a tertiary hospital with sepsis secondary to an abscess of the nasal vestibule and pustular eruptions of the nasal mucosa. …”
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Risk Factors for Hospital-Acquired Infection in a Neonatology Service by Hilda María Delgado Acosta, Sadis Suárez del Villar Seuret, Mabel Vega Galindo

“…Infants whose mothers had presented vaginal sepsis had a higher risk for infection (62, 3%, OR = 5.9). …”
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mTOR Modulates the Endoplasmic Reticulum Stress-Induced CD4+ T Cell Apoptosis Mediated by ROS in Septic Immunosuppression by Hao Wang, Jianwei Chen, Guangxu Bai, Wen Han, Ran Guo, Na Cui

“…Introduction. When sepsis attacks the body, the excessive reactive oxygen species (ROS) production can result to endoplasmic reticulum stress (ERS) and eventually cause lymphocyte apoptosis. …”
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Urinary I-FABP, L-FABP, TFF-3, and SAA Can Diagnose and Predict the Disease Course in Necrotizing Enterocolitis at the Early Stage of Disease by Stepan Coufal, Alena Kokesova, Helena Tlaskalova-Hogenova, Barbora Frybova, Jiri Snajdauf, Michal Rygl, Miloslav Kverka

“…Next, we compared their levels with the type of the disease (NEC or sepsis) and its severity. Already at the time of NEC suspicion, infants who developed NEC had significantly higher levels of all tested biomarkers than controls and higher levels of I-FABP and L-FABP than those who will later develop sepsis. …”
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Morbidity and mortality patterns of preterm low birthweight neonates admitted to referral hospitals in the Amhara region of Ethiopia: retrospective follow-up study by Yalemtsehay Dagnaw Genie, Belete Fenta Kebede, Mulualem Silesh Zerihun, Desalew Tilahun Beyene

“…Hypothermia, sepsis, respiratory distress, jaundice and congenital anomalies were the common morbidities. …”
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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

“…The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung injury, as indicated by alleviated lung pathological changes and infiltration of proteins and leukocytes. …”
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Impact of Inappropriate Empiric Antimicrobial Therapy on Mortality of Septic Patients with Bacteremia: A Retrospective Study by Saoraya Lueangarun, Amorn Leelarasamee

“…Case record forms of patients diagnosed as sepsis, severe sepsis, or septic shock with positive hemoculture during 2009 were retrieved from the medical wards, Siriraj Hospital. …”
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