Clinical diagnostic performance of droplet digital PCR for pathogen detection in patients with Escherichia coli bloodstream infection: a prospective observational study by Hiroki Kitagawa, Masato Kojima, Kayoko Tadera, Shuta Kogasaki, Keitaro Omori, Toshihito Nomura, Norifumi Shigemoto, Eiso Hiyama, Hiroki Ohge

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Assessment of urine CCL2 as a potential diagnostic biomarker for acute kidney injury and septic acute kidney injury in intensive care unit patients by Yuan Peng, Qin Wang, Fang Jin, Tao Tao, Qihong Qin

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Massively Parallel Screening of Toll/Interleukin‐1 Receptor (TIR)‐Derived Peptides Reveals Multiple Toll‐Like Receptors (TLRs)‐Targeting Immunomodulatory Peptides by Yun Lim, Tae Kyeom Kang, Meong Il Kim, Dohyeon Kim, Ji Yul Kim, Sang Hoon Jung, Keunwan Park, Wook‐Bin Lee, Moon‐Hyeong Seo

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A New Approach to Non-Invasive Microcirculation Monitoring: Quantifying Capillary Refill Time Using Oximetric Pulse Waves by Yuxiang Xia, Xinrui Wang, Zhe Guo, Xuesong Wang, Zhong Wang

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Establishment and Validation of a Machine‐Learning Prediction Nomogram Based on Lymphocyte Subtyping for Intra‐Abdominal Candidiasis in Septic Patients by Jiahui Zhang, Wei Cheng, Dongkai Li, Guoyu Zhao, Xianli Lei, Na Cui

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Long-term impact of molecular epidemiology shifts of methicillin-resistant Staphylococcus aureus on severity and mortality of bloodstream infection by Norihito Kaku, Masaki Ishige, Go Yasutake, Daisuke Sasaki, Kenji Ota, Fujiko Mitsumoto-Kaseida, Kosuke Kosai, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

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Predicting early diagnosis of intensive care unit-acquired weakness in septic patients using critical ultrasound and biological markers by Ling Lei, Liang He, Tongjuan Zou, Jun Qiu, Yi Li, Ran Zhou, Yao Qin, Wanhong Yin

Subjects: “…Sepsis…”
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Protective Effect of Shenfu Injection against Sepsis-induced Acute Lung Injury by Suppressing Inflammation and Apoptosis Through the Regulation of the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Pathway by Li-Juan Cao, Hai-Tang Xie, Zhong-Xia Chu, Yue Ma, Ming-Ming Wang, Shi Zhuang

“…Objective: Sepsis-induced acute lung injury (ALI) is a clinically critical condition with a high mortality rate. …”
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C5a/C5aR regulates Th1/Th2 imbalance in sepsis-associated lung injury by promoting neutrophil activation to increase PAD4 expression by Zhenbing Lu, Ling Zhu, Changlin Yi, Bi Su, Renying Wang

Subjects: “…Sepsis-associated lung injury…”
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Integration of Mendelian Randomization to explore the genetic influences of pediatric sepsis: a focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2 by Liuzhao Zhang, Quanwang Chu, Shuyue Jiang, Bo Shao

Subjects: “…Pediatric sepsis…”
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Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and apoptosis by Zang Binbin, Wang Lihui

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Antibiotic Prescription Practice and Resistance Patterns of Bacterial Isolates from a Neonatal Intensive Care Unit: A Retrospective Study from Jordan by Mariam Alameri, Lobna Gharaibeh, Mervat Alsous, Aseel Yaghi, Asma’a Tanash, Saqr Sa’id, Hanan Sartawi

Subjects: “…neonatal sepsis…”
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Meropenem Continuous Infusion in a Septic Patient with Periprosthetic Infection and End-Stage Renal Disease Undergoing Prolonged Intermittent Renal Replacement Therapy by Assiya Kadralinova, Maiya Konkayeva, Serik Dzhandayev, Aidos Konkayev

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Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study by Marie-Angélique Cazalis, Marie-Angélique Cazalis, Louis Kreitmann, Louis Kreitmann, Guillaume Monneret, Guillaume Monneret, Alexandre Pachot, Alexandre Pachot, Karen Brengel-Pesce, Karen Brengel-Pesce, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos

Subjects: “…sepsis…”
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Intestine-derived fibroblast growth factor 19 alleviates lipopolysaccharide-induced liver injury by regulating bile acid homeostasis and directly improving oxidative stress by Xiaomeng Tang, Jingjing Ning, Yilin Zhao, Shuyun Feng, Lujing Shao, Tiantian Liu, Huijie Miao, Yucai Zhang, Chunxia Wang

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Severe soft tissue injuries in multiple trauma patients—a challenge we can meet? A matched-pair analysis from the TraumaRegister DGU® by Nora Kirsten, Georg Maximilian Franke, Rolf Lefering, Tim Klüter, Matthias Weuster, Michael Müller, Sebastian Lippross, Andreas Seekamp, TraumaRegister DGU®, Stefanie Fitschen-Oestern

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Retrospective analysis of 300 microbial cell-free DNA sequencing results in routine blood stream infection diagnostics by Claudio Neidhöfer, Claudio Neidhöfer, Niklas Klein, Niklas Klein, Aylin Yürüktümen, Tessa Hattenhauer, Rebekka Mispelbaum, Christian Bode, Tobias A. W. Holderried, Achim Hoerauf, Marijo Parčina

Subjects: “…sepsis…”
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Investigation of the connection between triglyceride-glucose (TyG) index and the risk of acute kidney injury in septic patients - a retrospective analysis utilizing the MIMIC-IV da... by Pirun Zhang, Wenli Zhang, Yan Han, Tong Yang, Jiayi Zhong, Yun Han, Fang Lai

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Editorial: Infections in the intensive care unit, volume II by Lihui Wang, Bin Lin, Bin Lin, Zhongheng Zhang, Zhongheng Zhang, Yuetian Yu, Yuetian Yu

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Portal Hypertension Unmasked—Cavernous Transformation of the Portal Vein Following Portal Vein Thrombosis in a 9‐Year‐Old Female: A Case Report by Areej Motasim Khalil Seedahmed, Khalid Alshibli Dafalla Gasmalla, Hajer Yousuf Mohammed Ahmed, Sakina Eltahir Omer Mohammed, Yousif Omer Elgaili Yousif

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