PDK1/mTOR Signaling in Myeloid Cells Differentially Regulates the Early and Late Stages of Sepsis by Juan Du, Guoli Li, Mingxi Hua, Junyan Han, Yu Hao, Hui Zeng, Ang Li, Yaxian Kong

“…The cecal ligation and perforation (CLP) model is the gold standard for the polymicrobial sepsis. In the CLP mice, the myeloid cells play an important role in septic shock. …”
Get full text

Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy by Xuebiao Wei, Wenqiang Jiang, Zhonghua Wang, Yichen Li, Yuanwen Jing, Yongli Han, Linqiang Huang, Shenglong Chen

Subjects: “…Sepsis…”
Get full text

Knee Sepsis after Suprapatellar Nailing of an Open Tibia Fracture: Treatment with Acute Deformity and External Fixation by Chelsea E. Minoughan, Adam P. Schumaier, Frank R. Avilucea

“…The patient underwent suprapatellar intramedullary nailing and subsequently developed knee sepsis. Conclusion. This patient was managed with irrigation and debridements of the knee, fracture site, and intramedullary canal. …”
Get full text

Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner by Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

Subjects: “…Sepsis…”
Get full text

Harnessing artificial intelligence in sepsis care: advances in early detection, personalized treatment, and real-time monitoring by Fang Li, Shengguo Wang, Zhi Gao, Maofeng Qing, Shan Pan, Yingying Liu, Chengchen Hu

Subjects: Get full text

miR-16-5p aggravates sepsis-associated acute kidney injury by inducing apoptosis by Han Li, Junyan Duan, Tongtong Zhang, Yingjie Fu, Yue Xu, Hongjun Miao, Xuhua Ge

Subjects: Get full text

The S-S.M.A.R.T: A New Prognostic Tool for Patients with Suspected Sepsis in the Emergency Department by Ye Jin Kim, Jong Won Kim, Kyeong Ryong Lee, Dae Young Hong, Sang O Park, Young Hwan Lee, Sin Young Kim

“…Background. The sepsis screening tool is essential because it enables the rapid identification of high-risk patients and facilitates prompt treatment. …”
Get full text

A 41-Year-Old Patient with a Rare Cause of Severe Abdominal Sepsis Misdiagnosed as PID by Anastasia Mikuscheva, David Becker, Mark Thompson-Fawcett

Get full text

Staphylococcus aureus host cell invasion and virulence in sepsis is facilitated by the multiple repeats within FnBPA. by Andrew M Edwards, Jennifer R Potts, Elisabet Josefsson, Ruth C Massey

“…The relevance of these findings to pathogenesis was demonstrated using a murine sepsis model, which showed that multiple FnBRs were required for virulence. …”
Get full text

Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis by Praveen George, Mukta C. Srivastava, Jonathan Ludmir, Robert M. Reed, Semhar Z. Tewelde, Anuj Gupta, Michael T. McCurdy

“…Cardiac dysfunction is a common complication of sepsis in individuals with preexisting coronary disease and portends a poor prognosis when progressing to ischemic cardiogenic shock. …”
Get full text

Blockade of ICAM-1 Improves the Outcome of Polymicrobial Sepsis via Modulating Neutrophil Migration and Reversing Immunosuppression by Yan-jun Zhao, Wen-jing Yi, Xiao-jian Wan, Jun Wang, Tian-zhu Tao, Jin-bao Li, Jia-feng Wang, Xiao-ming Deng

“…Intercellular adhesion molecule-1 (ICAM-1) is a key adhesion molecule mediating neutrophil migration and infiltration during sepsis. But its role in the outcome of sepsis remains contradictory. …”
Get full text

The Resuscitation, Equilibrium and De-escalation (RED) strategy: a phased, personalized hemodynamic support in children with sepsis by Jaime Fernández-Sarmiento, Sushitra Ranjit, L. Nelson Sanchez-Pinto, Vinay M. Nadkarni, Roberto Jabornisky, Niranjan Kissoon

“…Cardiovascular involvement in sepsis entails both macro- and microcirculation abnormalities, with the main treatment objectives seeking to increase cardiac output and improve tissue perfusion, respectively. …”
Get full text

L-shaped association of body mass index with prognosis in individuals with sepsis: a multicenter cohort study by Kunping Cui, Xiangnan Teng, Wei liu, Xiaoxiao Zhao, Shanling Xu, Lang Bai

Subjects: Get full text

Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing by Yiqing Tong, Jianming Zhang, Yimu Fu, Xingxing He, Qiming Feng

“…Objective. Sepsis, a life-threatening clinical syndrome, is a leading cause of mortality after experiencing multiple traumas. …”
Get full text

Systemic inflammatory response index improves prognostic predictive value in intensive care unit patients with sepsis by Tuo Xu, Shuaiwei Song, Ke Zhu, Yin Yang, Chengyu Wu, Naixue Wang, Shu Lu

Subjects: “…Sepsis…”
Get full text

The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate by Dimitrios Velissaris, Vasilios Karamouzos, Nikolaos Ktenopoulos, Charalampos Pierrakos, Menelaos Karanikolas

“…Introduction. Sepsis and its consequences such as metabolic acidosis are resulting in increased mortality. …”
Get full text

Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis by Chiu-Li Yeh, Li-Han Su, Jin-Ming Wu, Po-Jen Yang, Po-Chu Lee, Po-Da Chen, Chun-Chieh Huang, Der-Yirng Hsieh, Hsueh-Ju Wang, Sung-Ling Yeh, Ming-Tsan Lin

“…Mice fed with a high-fat diet were then assigned to sham (SH) and sepsis with saline (SS) or GLN (SG) groups. The SH group was subjected to laparotomy, while the sepsis group underwent cecal ligation and puncture (CLP). …”
Get full text

Research on screening key proteins related to the pathogenesis of sepsis associated encephalopathy based on DIA proteomics technology by Wu Shuhui, Hu Hongjie, Lu Yuru, Zhu Wei

Subjects: “…sepsis associated encephalopathy…”
Get full text

Is <i>Punica granatum</i> Efficient Against Sepsis? A Comparative Study of Amifostine Versus Pomegranate by Kazim Sahin, Sena Sahin Aktura, Ilkay Bahceci, Tolga Mercantepe, Levent Tumkaya, Atilla Topcu, Filiz Mercantepe, Omer Faruk Duran, Huseyin Avni Uydu, Zihni Acar Yazici

Subjects: Get full text

SIRT5‐mediated HOXA5 desuccinylation inhibits ferroptosis to alleviate sepsis induced‐lung injury by Lei Wang, Heng Fan, Min Sun, Ji‐Hui Ye

Subjects: Get full text