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Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01“…Also, using mammalian cells that exclusively or predominately express IP3R1, to which Bok binds strongly, and a fluorescent Ca2+-sensitive dye or a genetically-encoded Ca2+ sensor, we explored how endogenous and exogenous Bok controls the Ca2+ mobilizing function of IP3R1, and whether Bok phosphorylation at Ser-8, or replacement of Ser-8 with a phosphomimetic amino acid, is regulatory. …”
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6402
Assessing the acute effect of compression socks on improving arterial compliance in young volunteers
Published 2025-01-01“…Mean arterial blood pressures (MAPs) were measured at the upper arms and ankles on both sides. Sensor cuffs were attached over socks to estimate pressures exerted on arterial walls by the socks in the condition of wearing socks. …”
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6403
Cyberinfrastructure for machine learning applications in agriculture: experiences, analysis, and vision
Published 2025-01-01“…The dataset includes 1 terabyte (TB) of multimodal data, comprising Unmanned Aerial System (UAS) imagery (RGB and multispectral), as well as soil and weather sensor data. The two primary crops studied were corn and soybean, which are the state's most widely cultivated crops. …”
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6404
IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3
Published 2025-02-01“…BackgroundCyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. The production of this pathway, interferon-β (IFNβ), could suppress the growth of tumor cells, yet it is unclear whether ferroptosis is involved in IFNβ-induced cell death.MethodsThe effects of IFNβ on ferroptosis were analyzed in HT1080, 4T1, HCT116 and 786-O cells. …”
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6405
Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats
Published 2018-01-01“…Recent studies have indicated that autophagy and myocardial energy depletion play a major role in myocardial dysfunction during sepsis, a mechanistic target of rapamycin (mTOR) as a master sensor of energy status and autophagy mediator; however, there are little data describing its role during sepsis in the heart. …”
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6406
Comparing Soil pH Mapping from Multi-Temporal PlanetScope and Sentinel-2 Data Across Land Use Types
Published 2025-01-01“…Our findings demonstrate that sensor selection, land use, temporal phases, and modeling resolution significantly impact outputs. …”
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6407
Effect of Situational Interactive Respiratory Training System on Patients with Respiratory Dysfunction after Stroke
Published 2021-12-01“…Then, the patient faced the screen and aligns his mouth with the pressure sensor of the training system to perform lip-respiratory breathing. …”
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6408
App-Based Ecological Momentary Assessment of Problematic Smartphone Use During Examination Weeks in University Students: 6-Week Observational Study
Published 2025-02-01“…Data collected from the Big4+ app, including self-reports on mood, sleep, and appetite, as well as passive sensor data (GPS location, acceleration, and steps) were used to evaluate overall health. …”
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6409
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Impact of the initiation of isCGM soon after type 1 diabetes mellitus diagnosis in adults on glycemic indices and fear of hypoglycemia: a randomized controlled trial
Published 2025-01-01“…Data on glycemic indices and fear of hypoglycemia (FoH) in newly diagnosed T1DM patients are limited.AimTo assess the impact of initiating intermittently scanned CGM (isCGM) within 1–6 months of diagnosis on glycemic control and FoH in adults with T1DM.Subjects and methodsAfter wearing a blinded sensor for 14 days, participants were randomized (1:1) to either isCGM (intervention) or self-monitoring blood glucose (SMBG) with glucometers and blinded CGM (control). …”
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6412
Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD
Published 2025-02-01“…Discovery proteomics identified caveolin-1, a sensor of cellular cholesterol accumulation, as a key promoter of ABCA1 endolysosomal trafficking. …”
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6413
A Miniaturized Low-Weight 2.4 GHz Circularly Polarized Antenna Using 3D Printing Technology
Published 2024-01-01“…This proposed antenna with a lightweight of 1.7 g can maintain a stable landing from the air, which can be deployed from air vehicles and to build an outdoor sensor network.…”
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6414
Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
Published 2025-01-01“…Conclusion We discovered that the hepatic vascular niche acts as a delicate sensor to even short-term nutritional alterations during the development of MASLD/MASH. …”
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6415
Isoacid supplementation influences feed sorting, chewing behaviors, and enteric methane emissions differentially in mid-lactation dairy cows depending on dietary forage level
Published 2025-02-01“…Enteric CH4 and chewing activity (rumination and eating time) were measured using the GreenFeed system and sensor-based ear tag system, respectively. The particle size of each diet and ort from individual cows was measured using the Penn State Particle Separator, and a sorting index was calculated. …”
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6416
Estudio volumétrico de las canteras romanas de Rodadero de los Lobos – cortijo Piquín (sierra de Córdoba) mediante UAV LiDAR
Published 2025-01-01“…La prospección mediante el sensor LiDAR ha permitido la captura de datos de la superficie del terreno, hasta este momento inéditos, debido a lo escarpado del mismo y la frondosidad de la vegetación, que dificultan la prospección superficial. …”
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6417
Development of an Alternative Protocol to Study Muscle Fatigue
Published 2025-01-01“…When measuring real-time in vivo muscle fatigue with electromyography (<b>EMG</b>), data collection can be compromised by premature sensor removal or environmental noise; therefore, the objective of this study was to develop a postmortem in vivo methodology to induce muscle fatigue and measure it using EMG. …”
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6418
Accuracy of noninvasive total haemoglobin measurement for detecting anaemia in infants: a cross-sectional study in a well-child care clinic, Khon Kaen, Thailand
Published 2024-12-01“…Spectrophotometric haemoglobin (SpHb) was measured using Masimo Rad-67 with Rainbow DCI-mini Sensor. These values were compared with conventional laboratory analysis (HbLab) performed on the same day.Primary and secondary outcome Differences between Hb values using the two methods were analysed using the Bland–Altman method. …”
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Perfluorooctanoic acid induces abnormal heart development via aryl hydrocarbon receptor-mediated oxidative stress and apoptosis in zebrafish larvae
Published 2024-12-01“…The aryl hydrocarbon receptor (AHR) is a critical environmental sensor capable of inducing oxidative stress and cell apoptosis. …”
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