Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis by Célia Alecki, Javeria Rizwan, Phuong Le, Suleima Jacob-Tomas, Mario Fernandez Comaduran, Morgane Verbrugghe, Jia Ming Stella Xu, Sandra Minotti, James Lynch, Jeetayu Biswas, Tad Wu, Heather D. Durham, Gene W. Yeo, Maria Vera

“…Stress-mediated HSPA8 mRNA localization to the dendrites is impaired by depleting fused in sarcoma—an amyotrophic lateral sclerosis-related protein—in cultured spinal cord mouse motor neurons or by expressing a pathogenic variant of heterogenous nuclear ribonucleoprotein A2/B1 in neurons derived from human induced pluripotent stem cells. …”
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The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression by Tian Yi Kang, Hua Rong Yang, Jie Zhang, Dan Li, Jie Lin, Li Wang, XiaoPing Xu

“…Here, we have utilized a whole mouse genome oligo microarray (4*44K) to analyze gene expression level of female BALB/c mice (implanted with EMT-6 sarcoma cells) after treatment with low, medium, and high-dose CA (5 mg/kg, 10 mg/kg, and 20 mg/kg), docetaxel, interferon, and normal saline separately at 6 time points (3rd, 6th, 9th, 12th, 15th, and 18th days after administration). …”
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A Disentangled Representation-Based Multimodal Fusion Framework Integrating Pathomics and Radiomics for KRAS Mutation Detection in Colorectal Cancer by Zhilong Lv, Rui Yan, Yuexiao Lin, Lin Gao, Fa Zhang, Ying Wang

“…Kirsten rat sarcoma viral oncogene homolog (namely KRAS) is a key biomarker for prognostic analysis and targeted therapy of colorectal cancer. …”
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Liposarcoma in the Inguinal Canal: Challenges in Preoperative Diagnosis and Importance of Routine Pathological Examination of “Hernia Sacs” by Christopher A. Febres-Aldana, Jin Min, Marc Rafols, Irvin Willis, John Alexis

“…Liposarcoma is the most common histologic subtype of soft tissue sarcoma in the retroperitoneum. The distinction of primary cord liposarcomas, which arise in and are confined to the inguinal canal, from inguinoscrotal extension of a retroperitoneal tumor is mandatory. …”
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Pathogenicity role of human herpesvirus-8 in patients with acute myeloid leukemia by Zahraa Ali Abdullah, Luma Amer Yasir, Ruqaya Munther J. Ewadh, Shakir H. Mohammed Al. Alwany

“…BACKGROUND: Certain hematologic cancers, including Kaposi’s sarcoma (KS), have been associated with the pathogenicity of human herpesvirus-8 (HHV-8). …”
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An Analysis of Biopsies for Suspected Skin Cancer at a Tertiary Care Dermatology Clinic in the Western Cape Province of South Africa by Johann de Wet, Minette Steyn, Henry F. Jordaan, Rhodine Smith, Saskya Claasens, Willem I. Visser

“…The most commonly occurring malignancies were basal cell carcinoma (BCC) (54.8%), squamous cell carcinoma (SCC) (18.9%), squamous cell carcinoma in-situ (SCCI) (8.0%), Kaposi’s sarcoma (KS) (6.7%), malignant melanoma (MM) (6.1%), and keratoacanthoma (KA) (4.6%). …”
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TMEM147 Correlates with Immune Infiltration and Serve as a Potential Prognostic Biomarker in Hepatocellular Carcinoma by Sheng Cheng, Jutang Li, Ming Xu, Qun Bao, Jiaoxiang Wu, Peng Sun, Bo Han

“…Mechanistic studies revealed that high TMEM147 expression was linked to the B lymphocyte, antigen response, IL6 signaling pathway, cell cycle, Kirsten rat sarcoma viral oncogene homolog (KRAS) signaling pathway, and myelocytomatosis oncogene (MYC) targets. …”
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Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma by Annika L. Gustafson, Annika L. Gustafson, Annika L. Gustafson, Adam D. Durbin, Kristin B. Artinger, Heide L. Ford, Heide L. Ford, Heide L. Ford

“…Rhabdomyosarcoma is a soft-tissue sarcoma that occurs most frequently in pediatric patients and has poor survival rates in patients with recurrent or metastatic disease. …”
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Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment by Fangling Li, Chengjing Liu, Wenyi Gu, Qianhe Xu, Dongmei Li, Dongdong Cao, Zhiyong Liu

“…Abstract Kaposi's sarcoma-associated herpesvirus (KSHV) infection can cause a variety of tumors and is one of the leading causes of death in acquired immune deficiency syndrome (AIDS) patients. …”
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Diagnostic and Surgical Challenges in Recurrent Dermatofibrosarcoma Protuberans: A Case Report by Yogesh Manek, Swati Deshpande, Darshana Tote, Suhas Jajoo, Bhagyesh Sapkale

“…Dermatofibrosarcoma Protuberans (DFSP) is a low-grade cutaneous soft-tissue sarcoma that originates in the dermis and infiltrates deeper structures. …”
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Prognostic Factors of Liposarcoma in Head and Neck by Shuo DING, Zhigang HUANG, Jugao FANG, Yang ZHANG, Lizhen HOU, Wei GUO, Gaofei YIN, Qi ZHONG

“…However, myxoid pleomorphic liposarcoma, pleomorphic fat sarcoma, and high Ki67 levels are indicators of poor prognosis. …”
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Long-term survival with pemetrexed-based chemotherapy in a patient with metastatic lung adenocarcinoma of unclear primary origin harboring MTHFR C677T(T/T) mutation: a case report by Yuan Yu, Yuan Yu, Yuan Yu, Nan-Jing Li, Nan-Jing Li, Nan-Jing Li, Nan-Jing Li, Jin Wang, Jin Wang, Jin Wang, Jin Wang

“…Sequential gene tests showed kirsten rat sarcoma viral oncogene homolog (KRAS) G13D mutation and epidermal growth factor receptor (EGFR) 19ins. …”
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Genetic Characteristics of the Rat Fibroblast Cell Line Rat-1 by Thomas Liehr, Stefanie Kankel, Eva Miriam Buhl, Sarah K. Schröder-Lange, Ralf Weiskirchen

“…Interestingly, the chromosomal imbalances found in Rat-1 cells resemble those found in human epithelioid sarcoma or liposarcoma. Additionally, we analyzed the transcriptome of Rat-1 cells through mRNA sequencing (mRNA-Seq) using next-generation sequencing (NGS). …”
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Utility of a New Artificial Dermis as a Successful Tool in Face and Scalp Reconstruction for Skin Cancer: Analysis of the Efficacy, Safety, and Aesthetic Outcomes by Fedele Lembo, Liberato Roberto Cecchino, Domenico Parisi, Aurelio Portincasa

“…The malignant tumors excised were basal cell carcinoma (68.75%), squamous cell carcinoma (18.75%), malignant melanoma (6.25%), and sarcoma (6.25%). The mean operating time was 41 minutes for the first operation (25–55) and 34 for the second (25–48). …”
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Challenges in the Diagnosis and Treatment of Aneurysmal Bone Cyst in Patients with Unusual Features by Ziyad M. Mohaidat, Salah R. Al-gharaibeh, Osama N. Aljararhih, Murad T. Nusairat, Ali A. Al-omari

“…This retrospective study involved medical record review of primary ABC patients with one or more of the following features: unusual clinical presentation with a mass or a pathological fracture especially at an unusual age, rare locations, radiological findings suggesting other diagnoses especially sarcoma, and a nondiagnostic histopathology of biopsy samples. …”
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Next generation sequencing uncovers multiple miRNAs associated molecular targets in gallbladder cancer patients by Rahul Saxena, Baskar Chakrapani, M. P. Sarath Krishnan, Amit Gupta, Sweety Gupta, Jayanta Das, Subash C. Gupta, Anissa A. Mirza, Shalinee Rao, Bela Goyal

“…Panther analysis revealed the insulin-like growth factor (IGF)-mitogen activated protein kinases (MAPK) cascade, p38 MAPK pathway, p53 pathway, and FAS (a subgroup of the tumor necrosis factor receptor) signaling pathway as highly enriched among dysregulated miRNAs. Kirsten rat sarcoma virus (KRAS), AR, and interferon gamma (IFN-γ) pathways were identified among the key pathways potentially amenable to targeted therapy. …”
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ENDOPROSTHESIS OF THE SHOULDER JOINT IN METASTATIC LESIONS OF THE PROXIMAL HUMERUS DURING IMMUNOSUPPRESSIVE THERAPY by M. V. Ivanova, V. Yu. Karpenko, A. V. Bukharov, V. A. Derzhavin

“…Morphologically most common are: osteosarcoma (55-63%), chondrosarcoma (17–25%) and Ewing’s sarcoma family of tumors (8–15%). Metastatic lesions of long bones occurs 2-4 times more common than primary tumors and often are diagnosed with breast cancer in 65–73%, of prostate cancer in 56–68% and lung cancer in 30–36% of patients. …”
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A Primary Pulmonary Glomus Tumor: A Case Report and Review of the Literature by Yasushi Ariizumi, Hirotaka Koizumi, Masahiro Hoshikawa, Takuo Shinmyo, Kouji Ando, Atsushi Mochizuki, Ayako Tateishi, Masatomo Doi, Mieko Funatsu, Ichirou Maeda, Masayuki Takagi

“…A 43-year-old female had undergone resection of a right lung tumor following a clinical diagnosis of carcinoid, sclerosing hemangioma, or other sarcoma. Histologically, the tumor comprised uniform small round to oval cells with centrally located nucleus, a clear cytoplasm, and apparent cell borders. …”
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Improvement in Automated Diagnosis of Soft Tissues Tumors Using Machine Learning by El Arbi Abdellaoui Alaoui, Stéphane Cédric Koumetio Tekouabou, Sri Hartini, Zuherman Rustam, Hassan Silkan, Said Agoujil

“…Soft Tissue Tumors (STT) are a form of sarcoma found in tissues that connect, support, and surround body structures. …”
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The safety and efficacy of immune checkpoint blockade in children, adolescents, and young adults: A systematic review and meta-analysis by Pedro C.A. Reis, João Evangelista Ponte Conrado, Mariana Macambira Noronha, Luís Felipe Leite da Silva, Erick Figueiredo Saldanha, Jonathan Metts

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