Rare Case Studies of Bilateral and Symmetric Sacroiliac Disease by Stephen Soloway, Alyxandra M. Soloway, Tyler G. Chin, Timothy Lieske

“…We present three rare conditions presenting with bilateral and symmetric SIJ disease, none of which is ankylosing spondylitis, Crohn’s colitis, ulcerative colitis, psoriatic arthritis, and reactive arthritis (Reiter syndrome); there are reports of concurrent SIJ disease in rheumatoid arthritis and SLE. Conclusion. The authors believe that SIJ disease is overlooked, is underdiagnosed, and can lead to incorrect treatment. …”
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Patellar Tendon Rupture after Lateral Release without Predisposing Systemic Disease or Steroid Use by S. De Giorgi, A. Notarnicola, G. Vicenti, B. Moretti

“…Nevertheless, in case of systemic diseases (LES, rheumatoid arthritis, and chronic renal insufficiency) that can weaken collagen structures, bilateral patellar tendon ruptures are described. …”
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Paraneoplastic Autoimmunity Associated with Testicular Myeloid Sarcoma and Chronic Myelomonocytic Leukemia by Jeffrey W. Craig, Richard J. Lin

“…Review of the literature identified the association between hematological malignancies, including chronic myelomonocytic leukemia, and paraneoplastic autoimmune phenomena with features similar to polymyalgia rheumatica and rheumatoid arthritis. Importantly, rheumatologic symptoms related to these disease entities may be easily dismissed as vague or unrelated complaints or treated as purely rheumatologic conditions, thus delaying the formal diagnoses. …”
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Granulomatous Hepatitis Secondary to Histoplasma Infection after Treatment with Infliximab by L. Barrera, J. Álvarez, M. Tapias, V. Idrovo, R. López

“…We present a case of a female patient with rheumatoid arthritis who received treatment with Infliximab during one and a half year; she developed granulomatous hepatitis secondary to Histoplasma infection. …”
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Leflunomide induced drug reaction with eosinophilia and systemic symptoms: A lesser known entity by Deepak Vashisht, Madhab Durga Tripathy, Sunmeet Sandhu, Rohit Kothari, Surbhi Vashisht, Arun Hegde

“…A 56-year-old lady, a known case of rheumatoid arthritis on treatment, developed diffuse exanthematous rash over body with fever and hepatic dysfunction, a month after administration of leflunomide. …”
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Clinical Insights into Tubercular Tenosynovitis: A Series of Eight Compound Palmar Ganglion Cases by Esa Gokulakrishnan, Prem K Kothimbakkam, Bharath Vadivelkumar, Vijayashankar Murugesan

“…Chronic flexor tenosynovitis of the wrist is often associated with tuberculosis in developing countries as opposed to rheumatoid arthritis in developed countries. A case series of compound palmar ganglion (eight cases) mimicking flexor tenosynovitis, for which magnetic resonance imaging (MRI) revealed conclusive evidence of cystic swelling and melon seed bodies. …”
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Th17 Cells in Immunity and Autoimmunity by Simone Kennedy Bedoya, Brandon Lam, Kenneth Lau, Joseph Larkin

“…However, strong evidence also implicates the Th17 lineage in several autoimmune disorders including multiple sclerosis, psoriasis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and asthma. …”
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Pseudoseptic Arthritis: A Case Series and Review of the Literature by Brian P. Oppermann, Jonida K. Cote, Stephanie J. Morris, Thomas Harrington

“…Pseudoseptic arthritis has been previously described in the literature in a variety of settings including rheumatoid arthritis and microcrystalline disease. Despite pseudoseptic arthritis being a described entity, there is little published data on this topic with no published reports since 1992. …”
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Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine by Vijay Kumar

“…However, further research has indicated sex/gender-based immune differences, which further increase higher incidences of various autoimmune diseases (AIDs), such as systemic lupus erythematosus (SLE), myasthenia gravis, and rheumatoid arthritis (RA) in females. On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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JC Virus PCR Detection Is Not Infallible: A Fulminant Case of Progressive Multifocal Leukoencephalopathy with False-Negative Cerebrospinal Fluid Studies despite Progressive Clinica... by Mohamed-Ali Babi, William Pendlebury, Steven Braff, Waqar Waheed

“…We describe a case with a false-negative PCR-based analysis for JC virus in cerebrospinal fluid (CSF) in a patient with clinical and radiological findings suggestive of progressive multifocal leukoencephalopathy (PML) who was on chronic immunosuppressive therapy for rheumatoid arthritis. Our patient developed rapidly progressive global decline with clinical and radiographic findings suggestive of PML, but JC virus PCR in CSF was negative. …”
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The effects of magnesium supplementation in autoimmune rheumatic diseases by Aaron Lerner, Jozélio Freire de Carvalho, Carina Benzvi, Motti Haimi

“…Only one study fulfilled the inclusion criteria and demonstrated that 300 mg/day of oral magnesium reduced insulin resistance in rheumatoid arthritis patients. The lack of studies on this subject shows that additional studies are required to understand the causal relationship between magnesium supplementation and disease treatment.…”
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High-Methionine Diet Attenuates Severity of Arthritis and Modulates IGF-I Related Gene Expressions in an Adjuvant Arthritis Rats Model by Mingxin Li, Lidong Zhai, Wanfu Wei

“…Rheumatoid arthritis, a synthesized form of adjuvant arthritis exhibited throughout many animal species, inhibits liver function and circulation of IGF-I and contributes to the degradation of skeletal muscle mass. …”
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QSAR modeling of benzoquinone derivatives as 5-lipoxygenase inhibitors by T.K. Shameera Ahamed, Vijisha K. Rajan, K. Muraleedharan

“…The inhibitors of 5-LOX control the overproduction of pro-inflammatory mediators known as leukotrienes (LTs) and thus have therapeutic relevance in the treatment of various diseases like asthma, rheumatoid arthritis, inflammatory bowel disease and certain types of cancers. …”
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Histoplasmosis Presenting as Granulomatous Hepatitis: Case Report and Review of the Literature by Nancy A. Rihana, Manasa Kandula, Ana Velez, Kumud Dahal, Edward B. O’Neill

“…We report a rare case of histoplasmosis that presented as persistent fever and abnormal liver function tests in a 66-year-old female with rheumatoid arthritis, receiving infliximab. Conclusion. Emphasizing histoplasmosis as a major cause of acute granulomatous hepatitis and fever of unknown origin in cell mediated immunodeficient population, this case highlights the need for high index of suspicion and the importance of prompt diagnosis since any delay of treatment can be life threatening in this population.…”
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Pyoderma Gangrenosum following Pacemaker Implantation: A Case Report and Review of Literature by Noura Ayoubi, Zaydi Javeed, Raymond Cutro, Brooke T. Baldwin

“…A 76-year-old male with a history of rheumatoid arthritis presented to the cardiology team with symptomatic bradycardia. …”
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Clinical utility of anti-cyclic citrullinated peptid and rheumatoid factor in chronic hepatitis B virus infection by Gokhan Sargin, Altay Kandemir

“…Methods: Ninety-seven patients with chronic HBV infection, 35 patients with rheumatoid arthritis (RA), and 30 healthy controls were included in the study. …”
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COVID-19: An Emerging Culprit of Inflammatory Arthritis by Muhammad Shariq Mukarram, Muhammad Ishaq Ghauri, Sehrish Sethar, Nasir Afsar, Amir Riaz, Khizra Ishaq

“…The musculoskeletal manifestations in these patients phenotypically resembled rheumatoid arthritis. These patients were treated successfully with low-dose glucocorticoids and disease-modifying antirheumatic drugs (DMARDs).…”
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Vascular cytoprotection, autoimmune disease, and premature atherosclerosis by Justin C Mason

“…Systemic inflammatory diseases including rheumatoid arthritis and systemic lupus erythematosus are associated with endothelial dysfunction, increased aortic stiffness, and accelerated atherogenesis. …”
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Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis by Qinghua Fang, Jiaxin Ou, Kutty Selva Nandakumar

“…Rheumatoid arthritis is a systemic, polygenic, and multifactorial syndrome characterized by erosive polyarthritis, damage to joint architecture, and presence of autoantibodies against several self-structures in the serum and synovial fluid. …”
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The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases by César Pacheco-Tena, Susana Aideé González-Chávez

“…Here, we review the pathogenesis of rheumatic diseases such as systemic lupus erythematous, rheumatoid arthritis, spondyloarthritis including ankylosing spondylitis, psoriasis, and Crohn’s disease and provide realistic approaches based on the logic of the danger model. …”
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