Navigating regulatory challenges in molecularly tailored nanomedicine by Ajay Vikram Singh, Preeti Bhardwaj, Aditya Kumar Upadhyay, Anselmo Pagani, Jyoti Upadhyay, Jolly Bhadra, Veronica Tisato, Manali Thakur, Donato Gemmati, Rudresh Mishra, Paolo Zamboni

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Plastics pollution: pathways, impacts, and regulatory challenges in marine environments by Malika Bel Hassen, Amel Bellaaj Zouari, Moufida Abdennadher, Jean-Claude Assaf, Mantoura Nakad, Rami Abboud, Yosra Khammeri, Mohamed Banni, Alberto Panzeri, Leonardo Gomes, Wael Hamd

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Ethical and regulatory issues in the application of 3D printing in orthopaedics: A scoping review by Francis Akpa-Inyang, Antoine Rocher, Megan O'Connor, Leonard Marais

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Who moved my scan? Early adopter experiences with pre- and post-market healthcare AI regulation challenges by Aviad Raz, Yael Inbar, Netta Avnoon, Liat Bela Lifshitz-Milwidsky, Barkan Hofman, Asaf Honig, Ziv Paz

“…Yet, it also constitutes a regulatory challenge, since such potential for learning may essentially change the algorithm and introduce new biases. …”
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Surveying local CAR T-cell manufacturing processes to facilitate standardization and expand accessibility by Deven Gupta, Beth Shaz

“…Addressing barriers such as cost, infrastructure, and regulatory challenges through standardization efforts and international collaboration could enhance the reproducibility, scalability, and accessibility of CAR T-cell therapies globally.…”
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A TECHNOLOGY PLATFORM FOR TRANSLATION OF ATMPS (ADVANCED THERAPY MEDICINAL PRODUCTS): THE EXAMPLE OF HUMAN EYE AND SKIN

“…These include 1) choosing the stem cell type and assessing a platform of technologies possibly common to multiple products, 2) familiarity with GMP manufacturing, reagent validation, and supply chain management, 3) product delivery issues and the additional regulatory challenges, 4) the relationship between clinical trial design and preclinical studies, and 5) the market approval requirements, scalability, pathways, and partnerships needed. …”
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Simulation and Analysis of a Novel Isopropanol and Acetone Production via Propylene by Marco Vaccari, Federico Baglioni, Leonardo Zando, Leonardo Tognotti

“…These findings provide insights into sustainable chemical production while addressing economic and regulatory challenges.…”
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Biomimetic nanovaccines in cancer therapy: mechanisms, efficacy, and clinical translation by Dilinaer Wusiman, Yu Wang, Minghao Wang, Jie Wang, Ruicheng Wu, Zhouting Tuo, Zhipeng Wang, Qingxin Yu, Zhaohong An, William C. Cho, Dengxiong Li, Wuran Wei, Dechao Feng

“…The review also addresses the technical and regulatory challenges in developing biomimetic nanovaccines and offers insights into future innovations that could facilitate their clinical translation.…”
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Peer-to-peer energy transaction matching mechanism balancing privacy-preserving ard result verifiability by PI Bingfeng, JIN Cheqing, QIAN Weining, HUA Song, ZHANG Shenbin

“…However, data privacy breaches and transaction regulatory challenges have emerged as critical barriers to its growth. …”
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Nanotechnology in Cancer Treatment: Innovative Approaches to Overcoming Drug Resistance in Tumors by Kirolos Eskandar

“…Additionally, this review provides a comprehensive analysis of recent clinical trials, offering insights into the real-world effectiveness of nanotechnology-based treatments. Ethical, regulatory challenges, and nanotoxicity are discussed to ensure the safe translation of nanomedicine to clinical practice. …”
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Application of Blockchain in Corporate Governance: Adaptability, Challenges and Regulation in BRICS by S. Kanojia

“…This paper aims to explore the possibilities of adopting blockchain technology within the arrays of internal governance mechanisms while emphasizing on the redressal to legal and regulatory challenges. The paper also critically analyzes the implication and utility of this evolved technology in the corporate governance systems of BRICS nations.…”
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Exploring Regulatory Frameworks for Exosome Therapy: Insights and Perspectives by Qiushi Li, Yuxia Li, Jiaqing Shao, Jianhua Sun, Lan Hu, Xia Yun, Chen Liuqing, Likun Gong, Shuxia Wu

“…However, their advancement is hindered by complex technological and regulatory challenges. This review outlines key considerations in the manufacturing process, quality management, and nonclinical evaluation relevant to EV‐based drug development. …”
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Natural preservation strategies: The potential of bioactive compounds from fruit and vegetable waste to reduce postharvest losses by Konstantinos Papoutsis, Zahra Shams, Mahboobeh Yazdani, Faraz Muneer, Mahbubjon Rahmatov, Nikwan Shariatipour, Evelyn Elizabeth Villanueva-Gutierrez, Monalisa Sahoo

“…Future research integrating advanced -omics technologies is encouraged to unravel the molecular interactions of these bioactive compounds, facilitating the development of environmentally friendly, scalable postharvest treatments. Addressing regulatory challenges and ensuring industry adoption will be crucial in transitioning toward natural alternatives for food preservation, ultimately reducing postharvest losses and promoting sustainability in the fresh produce supply chain.…”
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Health Claims on Botanical Substances Prohibited Pending Commission Evaluation: Case C–386/23, Novel Nutriology [2025] ECLI:EU:C:2025:304 by Andrea Parziale

“…The judgment provides guidance for food business operators marketing botanical products and highlights ongoing regulatory challenges in balancing consumer protection with commercial interests. …”
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The Impact of Financial Analysis and Foreign Investments on the Romanian Economy: A Case Study on Italian Capital by Andreea-Roxana Crocnan

“…For example, for foreign capital companies, such as many Italian firms operating in Romania, financial analysis aids in navigating economic and regulatory challenges, managing risks, and optimizing resources. …”
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TRADE IN SERVICES AND EMPLOYMENT: HARNESSING OPPORTUNITIES AND ADDRESSING CHALLENGES by GEORGETA ILIE

“…The main conclusion is that, despite the economic, geopolitical, technological or regulatory challenges, the strength of the services sector, due to the diversity of services, the dependence on services of all economic activities, the favourable service regulations, as well as the resilience of service industries in recent years, will continue to sustain the growth of trade in services and, implicitly, employment, thereby ensuring improvements in quality of life and economic development in all countries.…”
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Engineering copper and copper-based materials for a post-antibiotic era by Yingxian Wang, Tongqiang Wen, Fuchao Mao, Fuchao Mao, Fuchao Mao, Fuchao Mao, Shaozhe Yang, Qingwei Zhang, Xiuhong Fu, Chongkai Zhai, Chongkai Zhai, Chongkai Zhai, Chongkai Zhai, Hewei Zhang, Hewei Zhang, Hewei Zhang, Hewei Zhang, Hewei Zhang

“…This review aims to inform future efforts in overcoming the current limitations of copper-based antimicrobials and supporting their potential future integration into applications across medicine, public health, environmental protection, and agricultural innovation, contingent upon resolving current translational and regulatory challenges.…”
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Navigating the manufacturing, testing and regulatory complexities of regulatory T cells for adoptive cell therapy by Larissa A. Pikor, Sindhu Arivazhagan, Michael Mendicino, Sarmitha Sathiamoorthy

“…Discussion topics include the importance of starting material selection, the availability of GMP quality reagents and material, isolation and characterization of regulatory T cells, cGMP manufacturing considerations and limitations, the complexity of testing, release and distribution of cell-based therapies, as well as the regulatory challenges associated with Treg therapy. Treg cell therapies can be fraught with technical challenges which are mirrored by a sponsor’s ability to meet regulatory requirements. …”
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Generative AI and the future of innovation management: A human centered perspective and an agenda for future research by Vincenzo Corvello

“…The paper also outlines future research directions, focusing on diversity in AI adoption, the customization of GenAI in innovation processes, and the ethical and regulatory challenges posed by its widespread use. By examining how individuals and organizations adapt and reconfigure GenAI to fit specific needs, this paper contributes to a deeper understanding of the reciprocal relationship between technology and human agency, offering insights into the transformative potential of GenAI in enhancing innovation.…”
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Critical Analysis of Technologies Enhancing Supply Chain Collaboration in the Food Industry: A Nigerian Survey by Ebenezer Akinbamini, Alix Vargas, Angela Traill, Andrés Boza, Llanos Cuenca

“…The findings demonstrate that while the technologies hold substantial potential to optimize supply chain performance, their acceptance is constrained by infrastructural deficiencies, regulatory challenges, under-developed trust-building mechanisms, and limited technical expertise. …”
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