Performance of HPV E4 and p16INK4a biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study by David Jenkins, Mark H Stoler, Anne Hammer, Torben Steiniche, Lone Kjeld Petersen, Patti E Gravitt, Rikke Kamp Damgaard, Maurits NC de Koning, Wim GV Quint, John Doorbar, Johnny Kahlert

“…Women will be eligible if they have undergone active surveillance and have no previous record of hysterectomy, cone biopsy, and CIN2 or worse. Women will be randomly selected through the Danish Pathology Databank. …”
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Dietary omega-3 fatty acids affect the growth performance of broiler chickens reared at high stocking density by Shahgol Rahbari, Abdolreza Salehi, Seyed Davood Sharifi, Shirin Honarbakhsh

“…A total of 420 one-day-old broilers were used in 2 × 2 factorial arrangements with 2 levels of SD (low: 9 birds/ m2 and high: 17 birds/ m2) and 2 levels of omega-3 fatty acids (low and high omega-3; 0.057 and 0.5% of the diet, respectively) in a completely randomized design with 5 replicates for each treatment. …”
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Liraglutide Enhances the Activity of the ACE-2/Ang(1–7)/Mas Receptor Pathway in Lungs of Male Pups from Food-Restricted Mothers and Prevents the Reduction of SP-A by J. Fandiño, A. A. Vaz, L. Toba, M. Romaní-Pérez, L. González-Matías, F. Mallo, Y. Diz-Chaves

“…Sprague-Dawley pregnant rats were randomly assigned to 50% food restriction (MPFR) or ad libitum control (CT) groups at day of pregnancy 12 (GD12). …”
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Bladder mucosal smoothness predicts early recovery of urinary continence after laparoscopic radical prostatectomy by Le Yu, Ye Yan, Hongling Chu, Shaohui Deng, Jianfei Ye, Guoliang Wang, Yi Huang, Fan Zhang, Shudong Zhang

“…The total sample was randomly divided into a training set (n = 142) and a validation set (n = 61). …”
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The Effectiveness of Mindfulness-Based Stress Reduction Therapy on Disease signs and Symptoms and Psychological Distress in Women with Oral Lichen Planus by Fatemeh Sarebannezhad, Abdollah Omidi, Zahra Zanjani, Elaheh Ghasemzadeh Hoseini, Narges Gholizadeh

“…The sample comprised 36 women diagnosed with oral lichen planus, who were selected using purposive sampling and were then randomly assigned to either the control or experimental group. …”
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Characterizing avocado production systems for Ugandan exports: the need for consolidation and support for sustainable development by Peter Sseruwagi, Peter Sseruwagi, Edouard Lehmann, Paul Sigombe, Gabriel Ddamulira, Jan Willem Van Casteren, Pieterjan De Bauw

“…In this study, Hass avocado producers were randomly selected across Uganda. Field visits included farm and field surveys, GPS mapping of production areas, and soil sampling for wet-chemistry analysis. …”
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Pancreatic cancer mortality in South Africa: A case-control study by M L Nhleko, I Edoka, E Musenge

“…A matched case-control study with 1:1 matching was conducted using data collected by Statistics SA from 1997 to 2016. Controls were randomly selected to be as similar as possible to the cases, and matched by age, sex and year of death. …”
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Randomised, multicentre, placebo-controlled trial of fenofibrate for treatment of diabetic macular oedema with economic evaluation (FORTE study): study protocol for a randomised co... by Gerald Liew, Paul Mitchell, Bamini Gopinath, Helen Nguyen, Richard Kha

“…Participants will be randomly allocated in a 1:1 ratio to intervention and control groups. …”
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Influence of Regular Statin Intake on Prostate‐Specific Antigen Values, Prostate Cancer Incidence and Overall Survival in a Prospective Screening Trial (ERSPC Aarau) by Alkiviadis Papagiannakis, Maciej Kwiatkowski, Stephen F. Wyler, Ashkan Mortezavi, Lukas Manka, Marian S. Wettstein, Rainer Grobholz, Angelika Hammerer‐Lercher, Daniel Eberli, Lukas Werner Prause

“…Method N = 4,314 men from the Swiss section of the European Randomized Study of Screening for Prostate Cancer (ERSPC) were evaluated. …”
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Mechanistic insights into “Three Methods and Three Acupoints” Tuina therapy for improving spinal microcirculation and motor function in sciatic nerve injury model rats by Hanyu Zhang, Yingqi Zhang, Hourong Wang, Jiayue Liu, Jiawei Sun, Jinping Chen, Zhifeng Liu, Tianyuan Yu, Jian Shu

“…Methods: Thirty-six Sprague–Dawley rats were randomly assigned to four groups: normal, sham operation, model, and TMTP Tuina. …”
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Attenuating susceptibility to ascites in cold‐stressed broiler chickens fed canola meal‐based diets by supplementing arginine or guanidinoacetic acid, either alone or in combinatio... by Negin Delfani, Mohsen Daneshyar, Parviz Farhoomand, Sina Payvastegan, Younes Ali Alijoo, Gholamreza Najafi

“…Method A total of 450 one‐day‐old male broiler chicks were randomly allocated to 30 floor pens with 6 replications for each of the 5 treatments. …”
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Food safety practice and its associated factors among food handlers working in food and drinking establishments in Hargeisa, Somaliland by Mohamed Mussa Abdilahi, Jonah Kiruja, Abdisamad Shukri Ismail, Soheir H. Ahmed, Faisal Nooh, Ayanle Suleiman Ahmed, Abdiqathar Rashid Kulmie

“…Methods A community-based cross-sectional study was conducted from September 20 to October 20, 2024, involving 306 randomly selected food handlers in Hargeisa, Somaliland. …”
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Electroacupuncture Alleviates Neuropathic Pain and Negative Emotion in Mice by Regulating Gut Microbiota by Feng C, Pan H, Zhang Y, Ye Z, Zhou Y, Zou H, Wang K

“…Nevertheless, the relationship between the modulation of gut microbiota by EA and the amelioration of NP remains inadequately understood.Methods: Mice were randomly assigned to one of the three groups: the Control (Con) group, the EA group, and the Chronic Constrictive Injury (CCI) group (n = 12 each). …”
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PARP inhibitor‐based treatment in metastatic, castration‐resistant prostate cancer (mCRPC): A systematic review and meta‐analysis by Michela Roberto, Mattia Alberto Di Civita, Daniele Marinelli, Andrea Torchia, Nertila Cara, Giulia Maltese, Iolanda Speranza, Daniele Santini

“…Abstract Background We present a systematic review and meta‐analysis of randomized clinical trials (RCTs) with PARPi either as monotherapy or in combination with an androgen receptor‐targeted agent (ARTA) in first‐ and second‐line settings. …”
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Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…Relevant studies were selected based on established eligibility criteria, with clinical data carefully extracted for analysis. Eighteen randomized controlled trials involving a total of 1,077 participants were included in the analysis. …”
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Evaluation of topical 1% posaconazole therapy in refractory fungal keratitis by Murugesan Vanathi, Devendra K Yadav, Thirumurthy Velpandian, Nishat Hussain Ahmed, Manu Muraleekrishna, Abhijeet Beniwal, Neiwete Lomi, Noopur Gupta, Radhika Tandon, Maroof A Khan

“…Methods: Prospective longitudinal non-randomized open label dual-cohort study of 70 eyes of refractory fungal keratitis, 35 were recruited as posaconazole treatment (PCZ) group for topical 1% posaconazole therapy and compared to 35 eyes on conventional antifungal therapy. …”
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Goitre Prevalence and Urinary Iodine Concentration in School-Aged Children in the Ashanti Region of Ghana by Daniel Gyamfi, Yaw Amo Wiafe, Enoch Ofori Awuah, Evans Asamoah Adu, Emmanuel Kodie Boadi

“…This cross-sectional study was conducted among school-aged children (6–12 years) from randomly selected schools in the central and northern part of the Ashanti region, Kumasi Metropolis, and Ejura-Sekyedumase Municipality, respectively. …”
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Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning–Based Model Development and Validation Study by Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng, Hong-Shen Wang, Yi-Xin Kang, Shao-Bin Duan

“…MethodsA total of 4266 older patients (aged ≥ 65 years) with AKI admitted to the Second Xiangya Hospital of Central South University from January 1, 2015, to December 31, 2020, were included and randomly divided into a training set and an internal test set in a ratio of 7:3. …”
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Intensive Blood Pressure Control and Diabetes Mellitus Incidence for Patients with Impaired Fasting Glucose: A Secondary Analysis of SPRINT by Beiru Lin, Xiaochuan Liu, Sichen Yao, Zhigang Pan

“…We included participants with IFG at randomization, which was defined as fasting blood glucose (FBG) between 100 and 125 mg/dL. …”
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Effect of tDCS Synchronized FES on Lower Limb Motor and Balance Function of Traumatic Brain Injury Patients with Hemiplegia by LU Xiao, CHEN Hanbo, DING Lijuan, CHEN Xing, ZHENG Wenhua, WEI Ni, HE Linghui, LI Mengyun, LIU Chen, YAN Tiebin

“…ObjectiveTo observe the effect of transcranial direct current stimulation (tDCS) synchronized with normal walking pattern based on multi-channel functional electrical stimulation (FES) on lower limb motor and balance function in patients with traumatic brain injury hemiplegia.MethodsA total of 56 patients with TBI and hemiplegia were divided into synchronous group (<italic>n</italic>=21), FES group (<italic>n</italic>=20), and tDCS group (<italic>n</italic>=15) by using sealed-envelope randomization. The tDCS group was given head tDCS treatment and lower extremity sham FES treatment, the FES group was given head sham tDCS treatment and lower extremity FES treatment, and the synchronous group was given head tDCS treatment and lower extremity FES treatment. …”
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