Image-based robotic (ROSA® knee system) total knee arthroplasty with inverse kinematic alignment compared to conventional total knee arthroplasty by Henriëtte M. Eijking, Isobel M. Dorling, Emil H. van Haaren, Roel Hendrickx, Thijs Nijenhuis, Martijn G.M. Schotanus, Lee Bouwman, Jasper Most, Bert Boonen

“…Secondary outcomes include clinical metrics (leg alignment, implant and patient survival), surgical parameters (adverse events, surgery duration, blood loss, hospital stay length, medication use), patient-reported outcomes (symptoms, quality of life, pain), mobility and physical activity measurements, metabolic syndrome, cost-efficacy, and gait and continuous glucose monitoring. …”
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The potential impact of exercise on affect and neuroinflammation in older adults living with fibromyalgia: a scoping review by Taylor L. Taylor, Fitzgerald Dodds, McKenna Tharpe, Emily L. Zumbro, Michael Hankes, Raymond Jones, Deanna Rumble, Lisa Antoine, Kristen Allen-Watts, Andrew Sims, Reshu Chandra, Burel R. Goodin, Jarred Younger, Thomas W. Buford, Thomas W. Buford

“…Older adults living with FM experience longer pain symptom durations that can negatively impact their quality of life. Affect and neuroinflammation are potential factors that can exacerbate pain symptoms. …”
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Effect of photobiomodulation as preventive treatment of diabetic foot ulcer: randomised, controlled, double-blind, clinical trial protocol by Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori, Roselene Lourenço, Silvana Torres Perez, Cinthya Cosme Gutierrez Duran, Alexandre Rocha Santos Padilha, Tainá Caroline dos Santos Malavazzi

“…Assessments will be performed at the beginning of the study, after 30 days (clinical examination) and after 60 days (clinical examination, assessment of peripheral neuropathy (PN) and peripheral artery disease (PAD), blood and urine examinations and quality of life).Ethics and dissemination This protocol received approval from the Human Research Ethics Committee of Nove de Julho University and the Mandaqui Hospital Complex (certificate number: 66098522.0.3001.5511; final approval date: 22 June 2023). …”
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Application of humanistic care for patients with abdominal aortic aneurysm (人文关怀护理在腹主动脉瘤患者中的应用) by WANG Qianqian (王倩倩), QI Jiaxin (齐加新), JIANG Zhenzhen (蒋真真)

“…Conclusion Humanistic care nursing and psychological counseling is implemented in AAA patients, which realizes the perfect combination of psychosomatic nursing, provides patients with satisfactory humanistic medical experience, increases patients’ treatment compliance and treatment effect, improves patients’ quality of life, and promotes patients’ early recovery and community integration. …”
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Association between cardiovascular health and osteoporotic fractures: a national population-based study by Jun Ou, Tingting Wang, Ridan Lei, Mengting Sun, Xiaorui Ruan, Jianhui Wei, Jiabi Qin

“…Abstract Osteoporotic fractures are a major public health concern, particularly among the aging population, as they significantly contribute to morbidity, mortality, and reduced quality of life. While cardiovascular health (CVH) has traditionally been linked to cardiovascular disease outcomes, emerging evidence suggests it may also influence bone health. …”
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Causal relationship between 412 gut microbiota, 1,400 blood metabolites, and diabetic nephropathy: a randomized Mendelian study by Bo-Ning Cao, Cai-Yan Zhang, Zhen Wang, Yao-Xian Wang, Yao-Xian Wang

“…The results suggest that probiotic therapy may play a significant role in preventing diabetic nephropathy and improving the quality of life and survival rates of affected patients. …”
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Feasibility study of an experimental social space-oriented rehabilitation concept for people with intellectual and/or multiple disabilities: a study protocol by Kathrin Förster, Judith Gartmann, Andrea Boekel, Thilo Busche, Christoph Egen

“…Changes in individual participation, quality of life and rehabilitation goals will be assessed using a before-and-after comparison with questionnaires. …”
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A model based cost-utility analysis of Embedding referral to structured self-management education into standard practice (Embedding) compared to usual care for people with type 2 d... by Melanie J Davies, Alan Brennan, Danielle H Bodicoat, Daniel John Pollard, Anju Keetharuth, Michelle Hadjiconstantinou, Agnieszka Glab, Joesph P Mensa, Alison Northern

“…This is associated with a mean per patient incremental quality-adjusted life-year (QALY) estimate of 0.006, producing an incremental cost-effectiveness ratio of £8311 per QALY gained. …”
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Fighting Alzheimer’s with Movement: The Role of Physical Activity in Disease Management by Agnieszka Kosińska, Magdalena Balwierz, Karolina Kalinowska, Urszula Świrk, Jan Karczmarz, Joanna Orzechowska, Marika Gutowska, Michał Orzechowski, Aleksandra Paprocka, Paulina Fijałek

“…Evidence suggests that regular exercise helps improve cognitive function, slow disease progression, and enhance overall quality of life. This highlights the effectiveness of physical activity as a valuable, non-pharmacological approach to managing Alzheimer's. …”
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Effectiveness of Cognitive Behavioral Therapy Provided Through a Web Application for Subthreshold Depression, Subthreshold Insomnia, and Subthreshold Panic: Open-Labeled 6-Arm Rand... by Kayoko Taguchi, Mirai Miyoshi, Yoichi Seki, Shiori Baba, Eiji Shimizu

“…Some symptoms are present, causing significant difficulty in functioning and negatively impacting quality of life. Despite the attention given to subthreshold symptoms and the interventions for subthreshold symptoms being efficient in preventing the transition to psychiatric disease in primary care, reports on specific interventions are insufficient. …”
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Is longer really better? Results of a retrospective real-life cohort study evaluating the benefit of adding a weekly educational session to a traditional 8-week home-based pulmonar... by Cécile Chenivesse, Olivier Le Rouzic, Jean-Marie Grosbois, Sarah Gephine, Sophie Peres

“…A subgroup of participants received one additional supervised home session per week, including education and motivational support for daily physical activities and walking.Outcomes Health-related quality of life, dyspnoea, anxiety and depressive symptoms, fatigue and exercise tolerance were assessed at baseline (M0), at the end of PR (M2), and 14 months (M14) after M0.Results Baseline characteristics and assessments were similar between groups with an exception for long-term oxygen therapy (Gr1: 69.8% vs Gr2 53.0%, p<0.001) and noninvasive ventilation (Gr1: 38.6% vs Gr2: 29.8%, p=0.015). …”
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Should Endovascular Repair Be Reimbursed for Low Risk Abdominal Aortic Aneurysm Patients? Evidence from Ontario, Canada by Jean-Eric Tarride, Gord Blackhouse, Guy De Rose, James M. Bowen, Hamid Reza Nakhai-Pour, Daria O'Reilly, Feng Xie, Teresa Novick, Robert Hopkins, Ron Goeree

“…One-year health-related quality of life was lower in the EVAR patients compared to OSR patients. …”
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Lung cancer and risk of cardiovascular mortality by Chengshi Wang, Zhu Wang, Jing Yang, Songbo Zhang, Purong Zhang, Ye Yang

“…Clinical characteristics significantly modified cardiovascular mortality.ConclusionsIntegrating cardiovascular disease monitoring and proactive management into lung cancer treatment protocols is essential to the improvement of overall survival and quality of life for lung cancer patients, particularly those who were young or with advanced tumor stage.…”
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Preservative-free IOP-lowering medications: potential advantages by I.B. Alekseev, I.A. Koroleva

“…Elimination or minimization of adverse reactions accompanying long-term glaucoma therapy is an important resource to improve treatment compliance and, therefore, to prevent vision loss and to maintain the quality of life. Hence, glaucoma patients may benefit from the avoidance of the addit ional risk of ocular surface disorders resulting from preservative exposure.…”
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Patient-Reported Outcomes in Children Undergoing the Modified Green Procedure for Treating Sprengel’s Deformity: Results from a Multicentric Study by Giovanni Trisolino, Paola Zarantonello, Marco Todisco, Giovanni Luigi Di Gennaro, Grazia Chiara Menozzi, Philipp Scheider, Alessandro Depaoli, Diego Antonioli, Gino Rocca, Sebastian Farr

“…Several dedicated questionnaires such as QuickDASH, the Shoulder Pain Index and the Shoulder Disability Index (SPADI) and finally the UCLA Shoulder Scale were submitted to assess the quality of life of the subjects and the ability to practice certain activities, including work and sports. …”
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How Reliable Is Endoscopic Scoring of Postoperative Recurrence in Crohn Disease?: A Systematic Review and Meta-Analysis by Eline M. L. van der Does de Willebois, MD, Vittoria Bellato, MD, Marjolijn Duijvestein, MD, PhD, Susan van Dieren, MD, PhD, Silvio Danese, MD, PhD, Pierpaolo Sileri, MD, PhD, Christianne J. Buskens, MD, PhD, Andrea Vignali, MD, PhD, Willem A. Bemelman, MD, PhD

“…This study demonstrates a major variation in ER rates after ICR for CD, suggesting a high likelihood of inadequate diagnosis of disease recurrence, with potentially impact on quality of life and health care consumption. Therefore, there is an important need to improve endoscopic scoring of recurrent disease.…”
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Mental Health Assessment of the Population: Study Protocol of the MAP Research Program in Ukraine (MAP-U) and in Zurich (MAP-Z) by Viktoriia Yasenok, Eileen Neumann, Alessia Raineri, Julia Kopp, Seraina Rüegger, Tala Ballouz, Marco Kaufmann, Andrii Loboda, Vladyslav Smiianov, Andreas M. Baumer, Andreas M. Baumer, Erich Seifritz, Heiko Fabian Königstein, Anja Frei, Viktor Von Wyl, Viktor Von Wyl, Susi Kriemler, Andriana Kostenko, Milo A. Puhan

“…Secondary endpoints include participants’ health-related quality of life (EQ-5D-5L and EQ-VAS), experiences of somatic distress syndrome (PHQ-15), social isolation, social integration, and mental wellbeing (SWEMWBS).ResultsBaseline assessment starts in March 2024 with follow-ups occurring every 3 months for at least 2 years.ConclusionMAP will generate reliable, comparable, and high-quality epidemiological data to inform public mental health and healthcare policies in the Ukrainian population.ISRCTN Registryhttps://www.isrctn.com/ISRCTN17240415.…”
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The proof is in the pudding: patient engagement in studying cannabidiol in mild cognitive impairment by Antonia Keck, Julia-Sophia Scheuermann, Petra Scheerbaum, Elmar Graessel, Kirsten R. Müller-Vahl

“…Participants prioritized improvement in cognitive abilities (87.5%), followed by quality of life (63.6%), daily activities (55.7%), sleep (55.7%), pain (52.3%), mood (52.3%), behavior (48.9%), and anxiety (43.2%). …”
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Internal Facilitation by Health Assistants for the “WHO Lay Health Worker Dementia Care” in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Early diagnosis and tailored care are essential for managing these symptoms, improving quality of life, and reducing caregiver burden. Dementia affects a substantial portion of older people globally, especially in low- and middle-income countries like Uganda, where rural healthcare systems face challenges in dementia care access. …”
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Increasing the uptake of long-acting reversible contraception in general practice: the Australian Contraceptive ChOice pRoject (ACCORd) cluster randomised controlled trial longitud... by Danielle Mazza, Angela Taft, Kevin McGeechan, Kathleen Mcnamee, Natalie Amos, Kirsten I Black, Cathy J Watson, Marion Haas, Jeffrey F Peipert, Jayne Lucke

“…Based on the original ACCORd Study tools, the online survey will address long-term outcomes including contraceptive continuation rates and reproductive history, any unintended pregnancies, satisfaction and concerns with their current contraceptive method, and an assessment of quality of life. We will analyse data using binary regression models with generalised estimating equations and robust standard errors to account for clustering.Discussion Demonstration of sustained use, effectiveness at reducing unwanted pregnancies and cost-effectiveness of this strategy among this cohort of Australian primary care patients, will strengthen the policy and programme urgency of addressing wider dissemination of these strategies and replicating the study elsewhere.Ethics and dissemination The ACCORd Study received approval from the Monash University Human Research Ethics Committee: CF16/188-201000080. …”
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