Exosomal miR-122 derived from M2 macrophages induces osteogenic differentiation of bone marrow mesenchymal stem cells in the treatment of alcoholic osteonecrosis of the femoral hea... by Guoping Le, Riyou Wen, Huaixi Fang, Zhifa Huang, Yong Wang, Hanwen Luo

“…If not treated in time in clinical practice, it will seriously affect the quality of life of patients and even require hip replacement to treat alcoholic femoral head necrosis. …”
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Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…Secondary outcomes include Patient-Reported Outcome Measures (PROMs) using the Kujala score, International Knee Documentation Committee (IKDC) ‘Subjective Knee Form’, Tegner Activity score and EuroQol 5D-5 L for quality of life. Range of motion (ROM) is measured using the decline step-down test (DSDT). …”
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Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform? by Godsway Edem Kpene, Sylvester Yao Lokpo, Sandra A. Darfour-Oduro

“…While previous research in the Ho municipality has primarily examined risk factors, comorbidity, and quality of life of T2DM patients, this study specifically investigated mortality predictors among these patients. …”
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In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic... by Anders Bruun Mathiasen, Abbas Ali Qayyum, Erik Jørgensen, Steffen Helqvist, Annette Ekblond, Michael Ng, Kishore Bhakoo, Jens Kastrup

“…For safety, we followed symptoms, quality of life, and myocardial function for 6 months. …”
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Atopic dermatitis - the review by Joanna Wrona, Aleksandra Kaźmierczyk, Jędrzej Kęsik, Daria Madycka, Kacper Michta, Małgorzata Słaboń, Aleksandra Wójcik, Karol Stępniak, Wiktor Telega, Kinga Wnuczek

“…Innovative therapies and further research into AD pathogenesis hold promise for more effective disease control and improved quality of life for patients. …”
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Biopsy location and tumor-associated macrophages in predicting malignant glioma recurrence using an in-silico model by Pejman Shojaee, Edwin Weinholtz, Nadine S. Schaadt, Friedrich Feuerhake, Haralampos Hatzikirou

“…Abstract Predicting the biological behavior and time to recurrence (TTR) of high-grade diffuse gliomas (HGG) after maximum safe neurosurgical resection and combined radiation and chemotherapy plays a pivotal role in planning clinical follow-up, selecting potentially necessary second-line treatment and improving the quality of life for patients diagnosed with a malignant brain tumor. …”
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Effects of transcranial magnetic stimulation combined with extracorporeal shockwave therapy for poststroke spasticity: study protocol for a randomised controlled trial by Man Yang, Lu Liu, Peng-Yu Wang, Yang Zhu, Ling-Yi Liao, Qiu-Yi Peng, Yong Tao, Jin-Jing Liu, Xiang-Qin Fang, Shi-Hao Gao, Chang-Yue Gao

“…The secondary outcomes include the modified Tardieu scale for the degree of spasticity, the Fugl-Meyer assessment scale and range of motion (ROM) for motor function, the stroke-specific quality of life scale (SS-QOL) and modified Barthel index for activities of life, cortical excitability measured by TMS–surface electromyography (EMG), cerebral cortex oxygen concentrations measured by functional near-infrared spectroscopy (fNIRS) and Hmax/Mmax ratio measured by EMG.Ethics and dissemination This study protocol was approved by the Ethics Committee of the Army Medical Center of PLA (Approval No. 2024-04) on 24 January 2024. …”
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Rehabilitation diagnosis of patients with mine-explosive wounds of the lower leg based on the international classification of functioning, disability and health by O.E. Dorofieieva, K.S. Yarymbash, O.A. Glinyana, Yu.V. Syomych, I.T. Skrypchenko

“…Mine-blast injuries of the shin cause impairments at the structural level, but the majority of impairments in patients were found at the level of function, activity, and participation, which significantly affected their quality of life.…”
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Relationship Between Sedentary Lifestyle, Physical Activity and Stress in University Students and Their Life Habits: A Scoping Review with PRISMA Checklist (PRISMA-ScR) by Mariasole Antonietta Guerriero, Anna Dipace, Antonietta Monda, Antonella De Maria, Rita Polito, Giovanni Messina, Marcellino Monda, Marilena di Padova, Angelo Basta, Maria Ruberto, Emanuele Capasso, Fiorenzo Moscatelli, Pierpaolo Limone

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Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system by Jingrong Yang, Mengfan You, Jingxin Wang, Rongfei Sun, Lili Han, Xiaonan Liu, Kaibin Niu, Kaidi Xing, Juanping Sun, Wenge Su, Yifei Wang

“…BackgroundArrhythmias are prevalent cardiac disorders with significant impacts on patient quality of life and mortality. Amiodarone, a class III antiarrhythmic agent, is widely used to manage both atrial and ventricular arrhythmias due to its efficacy in prolonging the cardiac action potential and its multiple antiarrhythmic properties. …”
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Research progress on application of digital health interventions in patients with cutaneous ureterostomy (数字健康干预在输尿管皮肤造口患者中的应用进展) by JI Xuebi (吉学碧), WANG Jun (王俊), WANG Ping (王萍), YE Yingao (叶迎奥), WANG Haifeng (王海峰)

“…Concurrently, the accelerated advancement of mobile technology and information systems has led to the integration of digital health interventions, which significantly enhance the convenience for these patients, thereby elevating their quality of life and providing assistance. This paper reviews studies on concepts and related policies of digital health, and current status of clinical application of digital health interventions in patients with cutaneous ureterostomy. …”
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Mesalazine for People with Diverticular Disease: A Systematic Review of Randomized Controlled Trials by Andrea Iannone, Marinella Ruospo, Germaine Wong, Michele Barone, Mariabeatrice Principi, Alfredo Di Leo, Giovanni F. M. Strippoli

“…We estimated risk ratios (RR) for dichotomous outcomes (disease remission/recurrence, acute diverticulitis in symptomatic uncomplicated diverticular disease, need for surgery/hospitalization, all-cause/disease-related mortality, adverse events), mean differences (MD) or standardized MD (SMD) for continuous outcomes (quality of life, symptoms score, time to recurrence/remission), and their 95% confidence intervals (CI) using random-effects models. …”
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Classification of Epileptic Seizures by Simple Machine Learning Techniques: Application to Animals’ Electroencephalography Signals by Illia Pidvalnyi, Anna Kostenko, Oleksandr Sudakov, Dmytro Isaev, Oleksandr Maximyuk, Oleg Krishtal, Olena Iegorova, Ievgen Kabin, Zoya Dyka, Steffen Ortmann, Peter Langendorfer

“…Small electronic devices capable of doing that will improve the quality of life for epilepsy patients while also open new opportunities for pharmacological intervention. …”
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Curcumin ameliorates oxaliplatin-induced allodynia response and melanocortin downregulation in the spinal cord by Alma Nuril Aliya, Luke Wongso, Diah Ayu Wakita Trimanda, Risda Maulida, I Nengah Budi Sumartha, Samirah Samirah, Abdulloh Machin, Long Chiau Ming, Abdelhakim Bouyahya, Mahardian Rahmadi, Junaidi Khotib, Сhrismawan Ardianto

“…This effect limits the potential activity and decreases the cancer patient’s quality of life. Melanocortin and transient receptor potential ankyrin 1 (TRPA1) pathways are believed to be essential in recruiting an allodynia response. …”
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Therapeutic Efficacy of Ultrasound-Guided High-Voltage Long-Duration Pulsed Radiofrequency for Pudendal Neuralgia by Feng Ji, Shuzhuan Zhou, Caixia Li, Yongyan Zhang, Hua Xu

“…In conclusion, the ultrasound-guided high-voltage long-duration PRF approach not only reduced the pelvic pain caused by PN but also improved the quality of life by extending sitting time without nerve injury.…”
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Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China by Zixuan Hong, Ying Guo, Wenwen Cao, Chenglin Cao, Zhi Hu, Jing Yan, Ren Chen, Zhongliang Bai

“…To alleviate poor health and improve quality of life, pre-frail and frail older people need to adhere to their medication. …”
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Satisfaction, effectiveness, and usability of telerehabilitation for Parkinson's disease patients by Shohei Okusa, Hiroki Saegusa, Kazuya Miyakawa, Yuta Tsutsumi, Sae Ishida, Kyoko Nishikata, Tomonori Nukariya, Toshiki Tezuka, Yoshihiro Nihei, Yasuhiro Kitagawa, Shin-ichiro Kubo, Norihiro Suzuki, Jin Nakahara, Morinobu Seki

“…After 6 months, 91.1% expressed satisfaction with the telerehabilitation and 91.9% reported telerehabilitation had helped them develop an exercise routine, but the PDQ-39 showed no significant improvement in quality of life. The TUQ showed higher scores for Usefulness (76.1%), Ease of Use and Learnability (73.5%), Interface Quality (75.4%), and Satisfaction and Future Use (82.2%). …”
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Chronic lower back pain among occupational workers: effect of relaxation technique on quality of working life, pain and disability level with nurse-led intervention by Nabila ELSayed Sabola, Kamal Wifaq, Musaad M. Alruwaili, Rasha Kamal Mohamed Sweelam, Sabah Hassan El-Amrosy, Amal Yousef Abdelwahed

“…Recommendation Health education and awareness programs should be conducted to improve the quality of life for industrial workers with LBP. Additionally, occupational health nurses’ roles in the early detection and referral of LBP patients in diverse industrial settings should be strengthened.…”
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Feasibility, reliability, usability, and satisfaction of a digital medical device (ZEMY) for symptom management in patients treated for breast cancer: a single-arm interventional s... by Luis Teixeira, Christelle Levy, David Coeffic, Rim Ghorbal, Julien Dupin, Nazario Esposito, Olfa Derbel

“…The global patients’ quality of life remained stable during the study. Conclusions ZEMY provided satisfactory recommendations for the self-management of selected symptoms occurring during anti-cancer treatment and demonstrated good usability, but its feasibility was indemonstrable. …”
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Clinical course of spinal pain in adolescents: a feasibility study in a chiropractic setting by Steven J Kamper, Christopher G Maher, Mark J Hancock, Simon D French, Lise Hestbæk, Katherine A Pohlman, Michael S Swain, Laura RC Montgomery, Anika Young, Amber Beynon

“…Questionnaire measures included spinal pain, pain coping, quality of life, physical activity, clinical assessment findings and care delivered. …”
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