Targeting Cytokine-Mediated Inflammation in Brain Disorders: Developing New Treatment Strategies by Rahul Mallick, Sanjay Basak, Premanjali Chowdhury, Prasenjit Bhowmik, Ranjit K. Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

“…As research advances, the creation of personalized, cytokine-centered therapeutics has the potential to alter the therapy landscape for brain illnesses, giving patients hope for better results and a higher quality of life.…”
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Using Passive BCI for Personalization of Assistive Wearable Devices: A Proof-of-Concept Study by Asghar Mahmoudi, Morteza Khosrotabar, Klaus Gramann, Stephan Rinderknecht, Maziar A. Sharbafi

“…Assistive wearable devices can significantly enhance the quality of life for individuals with movement impairments, aid the rehabilitation process, and augment movement abilities of healthy users. …”
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Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives by Bryan Cleal, Yanbing Chen, Mandy Wäldchen, Hanne Ballhausen, Drew Cooper, Shane O'Donnell, Christine Knoll, Niklas Krug, Klemens Raile, Tebbe Ubben, Adrian Tappe, Dana Lewis, Ingrid Willaing, Timothy Skinner, Katarina Braune

“…ResultsParticipants consistently reported improvements in glycemia, physical health, sleep quality, emotional impact on everyday life, and quality of life. Knowledge of open-source AID systems was largely obtained through the #WeAreNotWaiting community, which was also the primary source of practical and emotional support. …”
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Physical Activity, Obesity, and Hypertension among Adults in a Rapidly Urbanised City by Qianqian Dun, Wanglin Xu, Maozhen Fu, Nengjian Wu, Justin B. Moore, Ting Yu, Xin Li, Yating Du, Biao Zhang, Qiaomai Wang, Yiting Duan, Ziqi Meng, Shuangshuang Tian, Yuliang Zou

“…Residents should be encouraged to engage in physical activities and maintain a healthy weight to improve their quality of life.…”
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Outcome measures after anterior cervical decompression and fusion surgery –non-respondents do not bias the results: A Finnish spine register (FinSpine) study by N. Klimko, N. Danner, H. Salo, A. Malmivaara, V. Leinonen, J. Huttunen

“…Outcomes were compared on neck and upper extremity pain, functional capacity, quality of life, sleep quality, return to work, regular use of pain medication, and opioid purchases 12 months after surgery. …”
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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

“…Questionnaires will be completed to assess pain and other aspects of health-related quality of life (HRQoL). Participants will be randomised to receive a 2-year course of TPTD injections 20 µg daily followed by a single intravenous infusion of 5 mg ZA, or to receive standard care, which will exclude the use of bone anabolic drugs. …”
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Effectiveness of mental health interventions for older adults in South Asia: A scoping review. by Hoimonty Mazumder, Farah Faizah, Easter Protiva Gain, Irfath Sharmin Eva, Kaniz Ferdouse Mou, Nobonita Saha, Farzana Rahman, Jyoti Das, A M Khairul Islam, Fazilatun Nesa, M Mahbub Hossain

“…Depression and anxiety were the most frequent mental health outcomes, followed by quality of life, cognitive function, self-esteem, physical performance, and many more.…”
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Effectiveness and safety of human placenta hydrolysate injection into subacromial space in patients with shoulder impingement syndrome: a single-blind, randomized trial by Du Hwan Kim, Myung Woo Park, Hyun Iee Shin, Byung Chan Lee, Don-Kyu Kim, Chul-Hyun Cho, Ye-Ji Kim

“…Conclusions Subacromial injections showed significant improvement in pain, functional level, and quality of life in patients with shoulder impingement syndrome. …”
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Efficacy and safety of left bundle branch area pacing versus biventricular pacing in heart failure patients with left bundle branch block: study protocol for a randomised controlle... by Lin Zhao, Liting Cheng, Junmeng Zhang, Zefeng Wang, Mengge Zhou, Zhuo Liang, Jieruo Chen, Yongquan Wu

“…The secondary outcomes are NT-proBNP, duration of the QRS complex, end systolic volume, end diastolic volume, the 6-minute walking test and quality of life (SF-36 scale), all causes of mortality, cardiovascular death, rehospitalisation rate of heart failure, other rehospitalisation rates, major complication rates, procedure costs and hospitalised dates.Ethics and dissemination This study has been approved by the Beijing Anzhen Hospital Medical Ethics Committee (No. ks201932). …”
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Effects of probiotics and its fermented milk on constipation: a systematic review by Jiaming Yan, Meiling Wu, Wei Zhao, Lai-Yu Kwok, Wenyi Zhang

“…Administration of probiotics significantly increased stool frequency (MD: 1.15 times/week; 95 % CI: 0.59 to 1.70; P < 0.000 1), improved bloating (MD: –0.48; 95 % CI: –0.89 to –0.07; P = 0.02), reduced abdominal pain (MD: –0.71; 95 % CI: –1.25 to –0.16; P = 0.01), and improved quality of life (MD: –0.73; 95 % CI: –1.37 to –0.10; P = 0.02). …”
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A data driven approach for soft tissue biomarker identification linked to Chiari-like malformation and syringomyelia by Jake Cumber, Jake Cumber, Emma Scales-Theobald, Emma Scales-Theobald, Clare Rusbridge, Clare Rusbridge, Clare Rusbridge, Kevin Wells, Kevin Wells

“…The associated neuro-disability in affected individuals compromises quality of life. CM is characterized by overcrowding of the brain and cervical spinal cord and is predisposed by skull-base shortening and miniaturization with brachycephalic toy dogs overwhelmingly represented. …”
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Effectiveness of the ARTHE-e app for exercise adherence in people with knee osteoarthritis: protocol for a randomised controlled trial by Bruno Pereira, Charlotte Lanhers, Emmanuel Coudeyre, Lech Dobija, Mathilde Pelletier-Visa, Alexis Bonhomme

“…The participants will undergo a comprehensive assessment, including the Exercise Adherence Rating Scale (EARS) at 2, 4 and 6 months, Knee Injury and Osteoarthritis Outcome Score, Evaluation of the Perception of Physical Activity, Tampa Scale of Kinesiophobia, European Quality of Life 5 Dimensions and 3 Lines and a Visual Analogue Scale rating of pain at baseline and 6 months. …”
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IBS as a diverse disease. A comprehensive review by Adrianna Dylik, Weronika Gryczyńska, Mikołaj Musiał, Łukasz Krawczak, Hanna Gulaczyk, Jan Spychalski, Mikołaj Kaczmarek, Wiktoria Grochowska, Maria Spychalska

“…The main problem is lower quality of life because of troublesome symptoms of the disease.                    …”
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Estimating rare disease prevalence and costs in the USA: a cohort study approach using the Healthcare Cost Institute claims data by Keith A Crandall, Christine M Cutillo, Ainslie Tisdale, Mahdi Baghbanzadeh, Reva L Stidd, Manpreet S Khural, Laurie J Hartman, Jeff Greenberg, Kevin B Zhang, Ali Rahnavard

“…Addressing these through improved data management in healthcare systems, increased research and education will lead to better diagnosis, care management and quality of life for patients with RD.Conclusion Data on patients with RD in the HCCI database were analysed for prevalence, costs, patient characteristics and treatment modification effects. …”
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How spinal GABAergic circuits modulate cerebral processing of postsurgical pain by Bruno Pradier, Daniel Segelcke, Nathalie Just, Mirjam Augustin, Nina Nagelmann, Cornelius Faber, Esther Pogatzki-Zahn

“…Post-surgical pain affects millions each year, hindering recovery and quality of life. Surgical procedures cause tissue damage and inflammation, leading to peripheral and central sensitization, resulting in pain at rest or mechanical and heat hyperalgesia. …”
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Nursing of a patient with oculomotor nerve paralysis treated with plum-blossom needle tapping therapy (梅花针叩刺法治疗1例动眼神经麻痹患者的护理体会) by LI Jinhuan (李金环), YIN Kexin (尹可欣), YANG Tingting (杨婷婷), CHEN Xiangping (陈香平), LIU Hongyan (刘红艳), JIA Zongcan (贾宗灿)

“…Oculomotor nerve palsy is a nerve condition that affects patient’s vision and quality of life. This article summarizes the nursing experience of a patient with mild oculomotor nerve paralysis treated with plum-blossom needle tapping therapy. …”
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Healthcare Utilization and Costs Among US Adolescents With Alopecia Areata by Markqayne Ray, Elyse Swallow, Kavita Gandhi, Christopher Carley, Vanja Sikirica, Travis Wang, Nicolae Done, James Signorovitch, Arash Mostaghimi

“…AA significantly affects quality of life, but evidence on the economic burden in adolescents is limited. …”
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Effects of a nurse-led peer support intervention for stroke survivors: protocol for a randomised controlled trial by Ying Wu, Janita Pak Chun Chau, Xiaojuan Wan, Limei Xu, Weijuan Gong

“…The secondary outcomes are psychosocial distress, social support, stigma towards disease, self-efficacy in managing chronic conditions and quality of life. Data will be collected at baseline, immediately after the intervention and 3 months after the intervention. …”
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Contribution of the Geodiversity knowledge to social, economic, and environmental health development by Cassio Silva, Edson Farias Mello, Gilberto Dias Calaes, Patricia Duringer Jacques, André Luiz Invernizzi

“…These include mining, where knowledge and proper utilization of essential mineral resources are crucial for human survival and quality of life; energy, which relies on petroleum, gas, coal, peat, and other minerals for nuclear energy generation, as well as for renewable energy sources like wind and solar power. …”
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Effect of endoscopic sinus surgery on eustachian tube function in adult patients with chronic rhinosinusitis by Mahmoud Atef Abdelghaffar Youssef, Nassim Talaat Nassim, MohamedNourEddin Bashir Alkeeb, Tareq Muhammad Algarf

“…Abstract Background Chronic rhinosinusitis (CRS) is a frequent chronic heterogeneous inflammatory disease of the upper airways and paranasal sinuses persistent for ≥ 12 weeks causing considerable healthcare expenses and reduction of patients’ quality of life due to severe tiredness and disappointment as well as diminished cognitive function. …”
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