Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…Adebrelimab, as a novel PD-L1 antibody, has not yet been proven for its efficacy and safety in adenocarcinoma of the esophagogastric junction. …”
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The Impact of Family Conflicts on Socio-Economic Prosperity: A Case Study of Muko Sub-County Rubanda District. by Akankwasa, Winfred

“…., the results of the study have revealed that some conciliators do not know the law related to inheritance and succession, that is why we recommend them to learn that law and other rules and regulation in force in the country; the findings of the study have proven that some conciliators are biased, so we recommend them to be impartial in order to mediate parts on family based conflicts fairly and the study concluded that it has been revealed by the findings that family based conflicts have a negative impact on economic prosperity of families where dealing with these conflicts bring about spending and consumes time that could be devoted in generating income activities. …”
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Role of Social Factors in Social Economic Status of Families in Kabale Municipality Kabale District. by Atukunda, Brian

“…., the results of the study have revealed that some conciliators do not know the law related to inheritance and succession, that is why we recommend them to learn that law and other rules and regulation in force in the country; the findings of the study have proven that some conciliators are biased, so we recommend them to be impartial in order to mediate parts on family based conflicts caused by alcohol up take fairly and the study concluded that it has been revealed by the findings that social factors have a negative impact on economic prosperity of families where dealing with these alcoholic beverages bring about spending and consumes time that could be devoted in generating income activities. …”
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Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote... by Viviana De Caro, Giada Tranchida, Cecilia La Mantia, Bartolomeo Megna, Giuseppe Angellotti, Giulia Di Prima

“…<b>Results</b>: PEG-based nanocomposites emerged as optimal and, following HXA insertion, the resulting powders revealed adequate bulk properties, making them useful as a pharmaceutical intermediate to produce ≈59 mm³ mini-tablets, compliant with the post-extraction socket. Moreover, they were proven ex vivo to be able to promote RSV and GA accumulation into the buccal tissue over time. …”
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A Prospective Randomized Trial Comparing 2 Different Paclitaxel-Coated Balloons in De Novo Coronary Artery Disease by Eun-Seok Shin, MD, PhD, Yongwhi Park, MD, PhD, Jong-Young Lee, MD, PhD, Ae-Young Her, MD, PhD, Min-Ku Chon, MD, PhD, Sunwon Kim, MD, PhD, Seung-Woon Rha, MD, PhD, Gyu Chul Oh, MD, PhD, Deok-Kyu Cho, MD, PhD, Bitna Kim, MS, Jang-Whan Bae, MD, PhD

“…Conclusions: The Genoss PCB, formulated with shellac and vitamin E as excipients, demonstrated angiographic outcomes comparable to a clinically proven PCB in the treatment of de novo CAD. (Compare the Safety and Efficacy of Genoss® DCB and SeQuent® Please NEO in Coronary De Novo Lesions; NCT05096442)…”
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Impact of irradiation conditions on therapy of Lewis lung carcinoma in mice using glucose-ethylenediamine carbon dots by Pavlo Lishchuk, Halyna Kuznietsova, Taisa Dovbynchuk, Nataliia Dziubenko, Liudmyla Garmanchuk, Sergei Alekseev, Mykola Isaiev, Nataliya Pozdnyakova, Artem Pastukhov, Nataliya Krisanova, Tatiana Borisova, Vladimir Lysenko, Valeriy Skryshevsky

“…In this study the nanoparticles with previously proven photoacoustic imaging properties, i.e. glucose-ethylenediamine carbon dots (GE-NPs), were tested for photoacoustic cancer therapy. …”
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Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial -... by Keiichi Fukuda, Satoshi Yasuda, Hiroyuki Tsutsui, Toyoaki Murohara, Kohtaro Abe, Koichiro Tatsumi, Junji Kishimoto, Yu Taniguchi, Yuichi Tamura, Koji Todaka, Shun Minatsuki, Kazuya Hosokawa, Yuko Kobayakawa, Takumi Inami, Nobutaka Ikeda

“…Edoxaban, the latest DOAC, also has proven efficacy and safety for those diseases in two large clinical trials; the ENGAGE-AF trial and HOKUSAI-VTE trial. …”
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Psychometric properties of the Arabic emotional and behavioral reaction to intrusions questionnaire among sample of Arabic speaking adults by Emmanuelle Awad, Diana Malaeb, Amthal Alhuwailah, Mai Helmy, Muna Barakat, Rabih Hallit, Sami El Khatib, Mohamad Rahal, Syed Arman Rabbani, Reem Alzayer, Nada H. Farrag, Rita El Hajjar, Jinan Mallouh, Souheil Hallit, Feten Fekih-Romdhane, Sahar Obeid, Rita ElHagar

“…Conclusion This study suggests that our Arabic translation of the EBRIQ is psychometrically proven to be reliable for use in Lebanon, United Arab Emirates, Egypt, Jordan, and Kuwait. …”
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Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study by David H Brewster, Victoria Cairnduff, Eila Watson, Amy Downing, Adam W Glaser, Penny Wright, William Cross, Conan Donnelly, Anna Gavin, Carol Rivas, Richard Wagland, Peter Selby, Luke Hounsome, Therese Kearney, Rebecca Mottram, Majorie Allen, Oonagh McSorley, Hugh Butcher, Paul Kind, James W H Catto, Dyfed Huws, Emma McNair, Lauren Matheson, Johana Nayoan, Mike Horton, Jessica Corner, Julia Verne

“…A comprehensive patient-reported outcome measure has been developed using generic and specific instruments with proven psychometric properties and relevance in national and international studies. …”
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A perspective on the current state of smartphone-based mobile applications for scar assessment by Peter Moortgat, Jill Meirte, Mieke Anthonissen, Koen Maertens, Thibau Demarbaix, Ulrike Van Daele

“…While only two scar-specific smartphone tools currently exist, applications, such as skin hydration and color measurement show promise for future integration. These tools have proven effective in assessing general skin characteristics but require further investigation of validity and reliability in a specific scar population. …”
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Improvement of crop production in controlled environment agriculture through breeding by Krishna Bhattarai, Andrew B. Ogden, Sudeep Pandey, Germán V. Sandoya, Ainong Shi, Amol N. Nankar, Murukarthick Jayakodi, Heqiang Huo, Tao Jiang, Pasquale Tripodi, Chris Dardick

“…Because of high energy and other production costs in CEA, only a limited number of food crops have proven themselves to be profitable to produce. One factor contributing to this situation may be a lack of optimized cultivars. …”
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Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies by Yuqing Zhang, Gordon Guyatt, Lin Wang, Hao Wen, Liming Lu, Gabriel Rada, Lai Wang, Shuqi Ge, Yu Dong, Camila Ávila, Xiaorong Tang, Neng-Gui Xu, Zhao Zeng, Camilo Vergara, Rouhao Chen, Xiaojing Wei, Wen Luo, Jing chun Zeng, Chun-Zhi Tang

“…Objective To provide a route map regarding systematic reviews (SRs) of acupuncture therapies that will meet two goals: (1) to identify areas in which more or better evidence is required and (2) to identify acupuncture applications that, although proven effective, remain underused in practice, and thus warrant more effective knowledge dissemination.Eligibility criteria We included SRs that conducted meta-analyses (MAs) of randomised controlled trials (RCTs) for this overview.Information sources We searched for SRs without language restrictions from January 2015 to November 2020 in four Chinese electronic databases and Epistemonikos database. …”
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Effect of botanical powders and the assassin bug, Alloeocranum biannulipes Mont. and Sign. (Hemiptera: Reduviidae) against Dinoderus porcellus Lesne (Coleoptera: Bostrichidae) infe... by Kitherian SAHAYARAJ, Antonio SINZOGAN, Manuele TAMO, Joelle TOFFA, Yêyinou Laura Estelle LOKO, Armand VODOUNNON, Innocent DJEGBE

“…(Euphorbiaceae)) leaf powders have proven to be efficient in the control of this pest. …”
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Biofilmed-PGPR: Next-Generation Bioinoculant for Plant Growth Promotion in Rice under Changing Climate by Jeberlin Prabina Bright, Hemant S. Maheshwari, Sugitha Thangappan, Kahkashan Perveen, Najat A. Bukhari, Debasis Mitra, Riyaz Sayyed, Andrea Mastinu

“…Analysis of the methanolic extract of the cyanobacterial- bacterial biofilm (CBB) showed the activity of antioxidants, such as 2-methoxy phenol and pentadecane, which are proven to improve plant-microbe interactions and plant growth, respectively. …”
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Shrimp White Spot Viral Infections Are Attenuated by Organic Acids by Regulating the Expression of HO-1 Oxygenase and β-1,3-Glucan-Binding Protein by Ioan Pet, Igori Balta, Nicolae Corcionivoschi, Tiberiu Iancu, Ducu Stef, Lavinia Stef, Iuliana Cretescu

“…The peritrophic membrane (PM) was proven essential to ensure Aq efficacy, as the infected and treated PM deficient shrimp (PM−) had a mortality rate of 27.8%, compared to only 9.34% mortality in the infected shrimp at 2% Aq and in the presence of PM (PM+). …”
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Noninvasive prenatal diagnosis (NIPD) of non-syndromic hearing loss (NSHL) for singleton and twin pregnancies in the first trimester by Huanyun Li, Shaojun Li, Zhenhua Zhao, Lingrong Kong, Xinyu Fu, Jingqi Zhu, Jun Feng, Weiqin Tang, Di Wu, Xiangdong Kong

“…Abstract Background Noninvasive prenatal diagnosis (NIPD) has been proven feasible for non-syndromic hearing loss (NSHL) in singleton pregnancies. …”
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Causal associations of ambient particulate matter 10 and Alzheimer’s disease: result from a two-sample multivariable Mendelian randomization study by Zehan Huang, Guodong He, Shuo Sun, Yingqing Feng, Yuqing Huang

“…However, the relationship between PM10 and risk of AD has not been proven to be causal. Thus we used two-sample multivariable Mendelian randomization (MR) to examine this relationship. …”
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Tools to improve discharge equity: Protocol for the pilot TIDE trial by Kirsten Austad, Cecilia Thai, Alegna Zavatti, Nhi Nguyen, Diana Bautista-Hurtado, Patrick Kenney, Noelia Lugo, Joo H. Lee, Howard Lanney, Ziming Xuan, Erika G. Cordova-Ramos, Mari-Lynn Drainoni, Brian Jack

“…The Tools to Improve Discharge Equity (TIDE) intervention leverages communication practices proven effective in addressing communication barriers to create language concordant discharge tools from hospital discharge paperwork. …”
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Vestibular Infant Screening-Rehabilitation (VIS-REHAB): protocol for a randomised controlled trial on Vestibular Rehabilitation Therapy (VRT) in vestibular-impaired children by Ruth Van Hecke, Leen Maes, Ingeborg Dhooge, Marieke Fontaine, Cleo Dhondt, Frederic Acke, Lena Van den Bossche, Helen Van Hoecke, Els De Leenheer

“…Although VRT is sufficiently proven and standardised in adults, there remains a lack of research examining its efficacy in children. …”
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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

“…Abstract Introduction Diesel exhaust particles (DEP) have been proven to aggravate asthma pathogenesis. We previously demonstrated that concurrent exposure to house dust mite (HDM) and DEP in mice increases both eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) and also results in higher levels of neutrophil-recruiting chemokines and neutrophil extracellular trap (NET) formation compared to sole HDM, sole DEP or saline exposure. …”
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